[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Istinye University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":647},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,82,0,25,[9,48,76,103,125,152,180,207,232,256,281,304,332,354,376,402,430,452,474,506,527,550,573,593,614],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100652595","dns-face-to-face-and-telerehabilitation-100652595",false,"NCT07775560","DNS: Face-to-face and Telerehabilitation","Dynamic Neuromuscular Stabilization Exercises: A Comparative Study of Their Effectiveness Via Face-to-Face and Telerehabilitation Delivery","Inclusion Criteria:\n\n* Aged between 18 and 35 years.\n* Not engaged in regular physical activity within the past 6 months.\n* No history of musculoskeletal disorders or chronic diseases.\n* Able to participate consistently in the exercise program.\n\nFor the Tele-DNS (TDNS) group: access to reliable internet and appropriate technical equipment for the duration of the intervention.\n\nExclusion Criteria:\n\n* Diagnosis or history of neurological, cardiovascular, respiratory, or metabolic diseases.\n* History of spinal or extremity surgery.\n* Pregnancy.\n* Presence of postural deformities or any orthopedic conditions that may affect balance.",true,"ALL","18 Years","35 Years",{"count":22,"type":23},34,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study aims to compare the effects of Dynamic Neuromuscular Stabilization (DNS) exercises delivered face-to-face (YDNS) and via tele-rehabilitation (TDNS) on respiratory function, balance, posture, core endurance, and deep stabilization system performance in healthy adults. A total of 34 participants will be randomly assigned to YDNS or TDNS groups and complete an identical 6-week DNS exercise program (3 sessions per week). Assessments will be conducted at baseline and post-intervention, including pulmonary function, Y-Balance Test, posture analysis, McGill's core stability tests, deep stabilization assessment, and patient satisfaction. All evaluations will be performed face-to-face by certified physiotherapists.",[29],"Healthy",[31,32,33,34],"core stabilization","balance","posture","respiratory parameters","RECRUITING","2026-08-19",{"date":38,"type":39},"2026-08-20","ACTUAL",{"date":41,"type":39},"2026-03-30",{"date":43,"type":23},"2026-12-30",{"name":45,"class":46},"Istinye University","OTHER",1,{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":12,"sex":18,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":24,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":47},"100613031","effects-of-blood-flow-restriction-aerobic-exercise-on-inflammation-hypoxia-exercise-capacity-and-lung-function-in-copd-100613031","NCT07261293","Effects of Blood Flow Restriction Aerobic Exercise on Inflammation, Hypoxia, Exercise Capacity, and Lung Function in COPD","Effects of Blood Flow Restriction Aerobic Exercise on Systemic Inflammation, Hypoxia, Exercise Capacity, and Pulmonary Functions in Patients With Chronic Obstructive Pulmonary Disease: A Prospective Randomized Controlled Trial","BFR-COPD","Inclusion Criteria:\n\n* Individuals aged between 40 and 80 years\n* Clinically stable patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD) according to GOLD 2024 criteria with post-bronchodilator FEV₁\u002FFVC \\\u003C 0.70\n* Stable clinical condition (no acute exacerbation within the past 4 weeks)\n* Individuals clinically evaluated and approved as suitable for pulmonary rehabilitation (PR) participation by a cardiology specialist\n* Functional capacity sufficient to participate in PR (e.g., 6-Minute Walk Test ≥150 m)\n* No contraindications to blood flow restriction (BFR) training (e.g., no peripheral vascular disease, no active thrombosis)\n* Ability to understand and follow instructions (adequate auditory and cognitive function)\n\nExclusion Criteria:\n\n* Acute exacerbation of COPD, hospitalization, or systemic corticosteroid treatment within the past 4 weeks\n* Severe cardiovascular disease (uncontrolled hypertension \\>180\u002F110 mmHg, myocardial infarction within the past 6 months, unstable angina, congestive heart failure NYHA Class III-IV)\n* Neurological or orthopedic conditions significantly limiting lower-extremity function (e.g., hemiplegia, amputation, severe osteoarthritis, knee prosthesis)\n* Severe renal impairment (GFR \\\u003C30 mL\u002Fmin\u002F1.73 m²) or severe hepatic failure\n* History of lower-extremity surgery within the past 3 months\n* Active malignancy or systemic infection\n* Anemia or chronic inflammatory\u002Fautoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease)\n* History of venous thromboembolism\n* Peripheral arterial disease\n* Physician-diagnosed sarcopenia\n* Psychiatric disorders (major depression, dementia, psychotic disorders) limiting adherence to the study protocol","40 Years","80 Years",{"count":22,"type":23},[26],"Purpose:\n\nThis study aims to compare the effects of the classical pulmonary rehabilitation (PR) program and blood flow restriction (BFR) applied during low-intensity aerobic exercise within PR on systemic inflammation, hypoxemia, exercise capacity, pulmonary function, respiratory muscle strength, and quality-of-life parameters in individuals with COPD.\n\nMethods:\n\nThis randomized controlled study will include 34 individuals with COPD, allocated into a BFR aerobic group and a control group. Both groups will receive core PR components, including diaphragmatic breathing, pursed-lip breathing, respiratory muscle training, and peripheral muscle strengthening. The BFR group will perform low-intensity aerobic exercise with blood flow restriction, while the control group will perform moderate-intensity aerobic exercise without BFR in accordance with standard PR protocols. All sessions will be supervised by a physiotherapist, twice per week, for eight weeks. Systemic inflammation markers, arterial blood gases, pulmonary function, exercise capacity, quality of life, and symptom scores will be assessed before PR, after the 8th session, and at the end of the program. Data will be analyzed using SPSS 26.0.\n\nExpected Contribution:\n\nThis study aims to provide evidence-based insights into the physiological and clinical effects of low-intensity BFR aerobic exercise within PR and to determine its potential advantages compared with classical PR. Additionally, it seeks to clarify whether low-intensity BFR aerobic exercise may serve as a better-tolerated alternative for COPD patients who experience exercise intolerance during moderate-intensity aerobic training.",[62],"COPD (Chronic Obstructive Pulmonary Disease)",[64,65,66,67],"COPD","BFR","Aerobic exercise","Exercise capacity","2026-08-13",{"date":70,"type":39},"2026-08-17",{"date":72,"type":39},"2025-12-01",{"date":74,"type":23},"2026-12-15",{"name":45,"class":46},{"id":77,"slug":78,"hasResults":12,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":24,"phases":86,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":47},"100652203","motivational-interviews-based-on-the-five-step-5a-model-on-obesity-risk-100652203","NCT07769736","Motivational Interviews Based on the Five-Step (5A) Model on Obesity Risk","The Effect of Structured Motivational Interviews Based on the Five-Step (5A) Model on Behavioral Change in Individuals at High Risk of Obesity in Family Medicine: A Mixed-Methods Randomized Controlled Trial Study Protocol","Inclusion Criteria:\n\n* Aged:18-64 years,\n* Body Mass Index (BMI): 25.0-35.0 kg\u002Fm² (Overweight or Class I Obesity)\n* Literate,\n* Voluntary agreement to participate.\n\nExclusion Criteria:\n\n* Body Mass Index (BMI): \\>35.0 kg\u002Fm²,\n* Active involvement in a concurrent weight loss program,\n* Current use of anti-obesity medication,\n* Severe psychiatric or cognitive disorders,\n* Pregnancy,\n* Missing more than one motivational interview session,\n* Orthopedic conditions precluding physical activity.","64 Years",{"count":85,"type":23},60,[26],"The goal of this clinical trial is to learn if a structured motivational interviewing program based on the Five-Step (5A) model works to promote healthy lifestyle behaviors in individuals at high risk of obesity. It will also learn about the effects on anthropometric measurements and physical activity levels. The main questions it aims to answer are:\n\n* Does this structured program promote healthy lifestyle behaviors in individuals at high risk of obesity?\n* To what extent does it increase participants' intrinsic motivation and readiness for behavioral change?\n\nParticipants will:\n\n* Attend structured interview sessions throughout the designated process\n* Visit the clinic at regular intervals for follow-up and evaluations\n* Record their lifestyle changes, physical activity levels, and experiences throughout the process",[89],"Obesity & Overweight",[91,92,93],"Obesity","Motivational Interviewing","Behavior Change","NOT_YET_RECRUITING","2026-08-12",{"date":97,"type":39},"2026-08-18",{"date":99,"type":23},"2026-09",{"date":101,"type":23},"2026-11",{"name":45,"class":46},{"id":104,"slug":105,"hasResults":12,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":12,"sex":18,"minAge":110,"maxAge":4,"enrollmentInfo":111,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":114,"conditions":115,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":4},"100651794","diastolic-shock-index-for-predicting-postspinal-hypotension-100651794","NCT07765342","Diastolic Shock Index for Predicting Postspinal Hypotension","Comparison of the Diagnostic Performance of the Diastolic Shock Index and Other Shock Indices in Predicting Postspinal Hypotension","Inclusion Criteria:\n\n* Age 50 years or older\n* Scheduled for elective unilateral inguinal hernia surgery\n* Scheduled to undergo surgery under spinal anesthesia\n* American Society of Anesthesiologists physical status I-III\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Emergency surgery\n* Bilateral inguinal hernia surgery\n* Contraindication to spinal anesthesia\n* Failure of spinal anesthesia or conversion to general anesthesia due to failed spinal block\n* Requirement for additional general anesthesia or deep sedation during surgery\n* Operation duration exceeding 120 minutes\n* Atrial fibrillation, atrial flutter, frequent ventricular ectopy, or other arrhythmias preventing reliable heart rate assessment\n* Presence of a permanent cardiac pacemaker\n* Severe valvular heart disease\n* New York Heart Association class III-IV heart failure\n* Preoperative use of vasopressor or inotropic therapy\n* Severe hepatic failure or end-stage renal disease\n* Neurological disease that may significantly affect autonomic nervous system function\n* Preoperative hemodynamic instability, defined as systolic arterial pressure \\\u003C90 mmHg or \\>180 mmHg, or heart rate \\\u003C50 or \\>120 beats\u002Fmin\n* Missing study data or inability to obtain records in accordance with the study protocol","50 Years",{"count":112,"type":23},85,"OBSERVATIONAL","This prospective observational study aims to evaluate the diagnostic performance of the preoperative Diastolic Shock Index in predicting postspinal hypotension and to compare its performance with other shock indices, including the Shock Index, Modified Shock Index, and Age Shock Index. The study will include patients aged 50 years and older undergoing elective unilateral inguinal hernia surgery under spinal anesthesia. Hemodynamic parameters will be recorded before and after spinal anesthesia as part of routine clinical monitoring. The primary outcome is the development of postspinal hypotension. Secondary outcomes include vasopressor requirement, total ephedrine dose, lowest intraoperative mean arterial pressure, and the diagnostic performance of the evaluated shock indices using receiver operating characteristic curve analysis. No additional intervention beyond routine anesthetic and perioperative care will be performed for study purposes.",[116],"Postspinal Hypotension","2026-08-11",{"date":119,"type":39},"2026-08-14",{"date":121,"type":23},"2026-08-21",{"date":123,"type":23},"2027-03-07",{"name":45,"class":46},{"id":126,"slug":127,"hasResults":12,"nctId":128,"briefTitle":129,"officialTitle":130,"acronym":131,"eligibilityCriteria":132,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":133,"enrollmentInfo":134,"targetDuration":136,"studyType":113,"phases":4,"briefSummary":137,"conditions":138,"keywords":140,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":47},"100644701","fear-avoidance-beliefs-and-physical-function-in-patients-with-lumbar-disc-herniation-100644701","NCT07674407","Fear-Avoidance Beliefs and Physical Function in Patients With Lumbar Disc Herniation","The Relationship Between Fear-Avoidance Beliefs and Trunk Muscle Endurance, Balance, and Functional Impairment in Patients With Lumbar Disc Herniation","FAB-LDH","Inclusion Criteria:\n\n* Aged between 18 and 65 years\n* Clinically and\u002For radiologically diagnosed with lumbar disc herniation\n* Presence of low back pain for at least 3 months\n* Sufficient cognitive capacity to understand and perform the assessment procedures\n* Ability to walk independently\n* Willingness to participate voluntarily and provide written informed consent\n\nExclusion Criteria:\n\n* History of lumbar spine surgery\n* History of neurological disorders, such as stroke or Parkinson's disease\n* Vestibular disorders or severe balance impairment\n* History of orthopedic injury or surgery affecting the lower extremities\n* Presence of rheumatological disease\n* Pregnancy\n* Severe pain or an acute inflammatory condition that prevents completion of the assessment procedures","65 Years",{"count":135,"type":23},65,"1 Day","Lumbar disc herniation is one of the most common causes of low back pain and is associated with substantial functional limitations and reduced quality of life, particularly among working-age individuals. Displacement of disc material toward the spinal canal may result in mechanical compression and inflammation of the nerve roots, leading to pain, restricted movement, and reduced functional performance.\n\nThe course of low back pain cannot be explained solely by biomechanical and anatomical factors. Psychosocial factors also play an important role in symptom persistence and functional outcomes. Within this context, the fear-avoidance model provides an important theoretical framework, suggesting that individuals may develop fear of movement and avoid physical activities because they believe these activities may increase pain or cause further injury. Over time, avoidance behaviors may contribute to physical deconditioning, reduced muscle function, and increased functional impairment.\n\nThe Fear-Avoidance Beliefs Questionnaire is commonly used to assess individuals' beliefs regarding the relationship between pain, physical activity, and work-related activities. Higher levels of fear-avoidance beliefs have been associated with greater pain severity, increased disability, and poorer physical performance in individuals with low back pain.\n\nTrunk muscle endurance plays a key role in maintaining spinal stability. Adequate endurance of the paraspinal and abdominal muscles supports mechanical stability of the spine and contributes to the safe performance of functional movements. The Biering-Sørensen Test and plank test are commonly used to assess trunk muscle endurance in clinical and research settings. The Biering-Sørensen Test evaluates the endurance of the trunk extensor muscles, whereas plank-based tests assess the endurance of the anterior and lateral trunk musculature.\n\nFunctional impairment in individuals with low back pain can be evaluated using the Oswestry Disability Index, a self-reported questionnaire that assesses limitations experienced during activities of daily living. Functional mobility and performance may also be evaluated using the Timed Up and Go test, which involves standing up from a chair, walking a short distance, turning, returning to the chair, and sitting down. This test reflects mobility, dynamic balance, and functional performance during daily activities.\n\nPostural control and balance may also be affected in individuals with low back pain. Reduced static balance performance can negatively influence functional activities and mobility. The Single-Leg Stance Test is a practical clinical measure used to assess postural stability and static balance.\n\nAlthough previous studies have examined associations between psychosocial factors and functional status in individuals with low back pain, studies evaluating the relationship between fear-avoidance beliefs, trunk muscle endurance, balance, and functional performance together remain limited. Identifying these relationships may contribute to the development of more comprehensive rehabilitation programs for individuals with lumbar disc herniation.",[139],"Disc Herniation",[141,142,32,143,144],"fear-avoidance beliefs","trunk muscle endurance","functional impairment","low back pain","2026-08-10",{"date":117,"type":39},{"date":148,"type":39},"2026-06-30",{"date":150,"type":23},"2026-10-30",{"name":45,"class":46},{"id":153,"slug":154,"hasResults":12,"nctId":155,"briefTitle":156,"officialTitle":157,"acronym":4,"eligibilityCriteria":158,"healthyVolunteers":12,"sex":18,"minAge":133,"maxAge":159,"enrollmentInfo":160,"targetDuration":4,"studyType":24,"phases":162,"briefSummary":163,"conditions":164,"keywords":167,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":174,"lastUpdatePostDateStruct":175,"startDateStruct":176,"completionDateStruct":177,"leadSponsor":179,"locationsCount":4},"100651673","high-amplitude-functional-exercises-in-older-adults-with-mild-cognitive-impairment-100651673","NCT07762235","High-Amplitude Functional Exercises in Older Adults With Mild Cognitive Impairment","Effects of Dual-Task-Based High-Amplitude Functional Exercises on Balance and Functional Mobility in Older Adults With Mild Cognitive Impairment","Inclusion Criteria:\n\n* Living independently\u002Factively in a nursing home.\n* Diagnosis of Mild Cognitive Impairment (MCI) based on a standardized screening test, with a Montreal Cognitive Assessment (MoCA) score of 18-25.\n* Ability to walk independently for at least 10 meters without an assistive device or with only a cane\u002Fsingle-point support.\n* Sufficient vision and hearing capacity to follow dual-task instructions and exercise directions, which may be corrected with glasses or hearing aids.\n* Stable medical condition that does not prevent participation in the exercise program throughout the study.\n\nExclusion Criteria:\n\n* Diagnosis of dementia or severe cognitive impairment based on cognitive screening (MoCA \\\u003C17).\n* Neurological conditions that primarily affect balance, such as Parkinson's disease, residual effects of stroke, multiple sclerosis, or cerebellar ataxia.\n* Severe osteoarthritis, active inflammatory joint disease, or a history of major orthopedic surgery within the previous 6 months that could limit exercise performance.\n* Uncontrolled hypertension, heart failure (NYHA Class III-IV), or cardiopulmonary instability causing symptoms during exercise.\n* Advanced vestibular pathology or severe loss of proprioception in the lower extremities that could be the primary cause of balance impairment.","85 Years",{"count":161,"type":23},36,[26],"This study will investigate the effects of dual-task-based high-amplitude functional exercises on balance and functional mobility in older adults with mild cognitive impairment. A total of 36 participants aged 65 years and older will be randomly assigned to either a high-amplitude functional exercise group or a traditional balance and mobility exercise group. Both groups will participate in exercise sessions four times per week for four weeks, with each session lasting 60 minutes. The effects of the exercise programs will be evaluated by assessing balance, functional mobility, dual-task performance, walking performance, fear of falling, and independence in daily activities before and after the intervention.",[165,166],"Mild Cognitive Impairment (MCI)","Exercises",[168,169,170,171,172,173],"Mild Cognitive Impairment","Older Adults","High-Amplitude Functional Exercises","Dual-Task Training","Functional Mobility","Dual-Task Cost","2026-08-09",{"date":68,"type":39},{"date":38,"type":23},{"date":178,"type":23},"2027-04-05",{"name":45,"class":46},{"id":181,"slug":182,"hasResults":12,"nctId":183,"briefTitle":184,"officialTitle":185,"acronym":4,"eligibilityCriteria":186,"healthyVolunteers":12,"sex":18,"minAge":187,"maxAge":19,"enrollmentInfo":188,"targetDuration":4,"studyType":24,"phases":189,"briefSummary":190,"conditions":191,"keywords":193,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":202,"startDateStruct":203,"completionDateStruct":204,"leadSponsor":206,"locationsCount":4},"100651514","bspts-and-core-stabilization-exercises-in-adolescents-with-idiopathic-scoliosis-100651514","NCT07761260","BSPTS and Core Stabilization Exercises in Adolescents With Idiopathic Scoliosis","Effects of Core Stabilization Exercises Combined With Barcelona Scoliosis Physical Therapy School Exercises on Trunk Rotation Angle and Core Muscle Endurance in Individuals With Adolescent Idiopathic Scoliosis: A Randomized Controlled Study","Inclusion Criteria:\n\n* Diagnosis of adolescent idiopathic scoliosis.\n* Cobb angle between 10° and 40°.\n* Risser sign between 0 and 3.\n* Ability to understand and perform the exercise instructions.\n* Willingness to participate in the study and provision of informed consent.\n\nExclusion Criteria:\n\n* Scoliosis associated with congenital, neuromuscular, or syndromic conditions.\n* Previous spinal surgery.\n* Presence of significant lower-extremity deformity or neurological disorder affecting balance or exercise performance.\n* Current participation in another scoliosis-specific exercise program.\n* Severe cardiopulmonary or systemic disease contraindicating exercise.\n* Inability to complete the assessment procedures or exercise program.","10 Years",{"count":161,"type":23},[26],"This study aims to investigate the short-term effects of adding core stabilization exercises to Barcelona Scoliosis Physical Therapy School (BSPTS) exercises in adolescents with idiopathic scoliosis. Participants will be randomly assigned to either a BSPTS exercise group or a BSPTS plus core stabilization exercise group. Both groups will participate in supervised exercise sessions twice a week for 6 weeks. The study will evaluate changes in trunk rotation angle and core muscle endurance as the primary outcomes, as well as dynamic balance, spinal appearance perception, postural awareness, and scoliosis-related quality of life.",[192],"Scoliosis Idiopathic Adolescent",[194,195,196,197,198,199,200],"Adolescent Idiopathic Scoliosis","Barcelona Scoliosis Physical Therapy School","Core Stabilization Exercises","Trunk Rotation Angle","Core Muscle Endurance","Dynamic Balance","Postural Awareness","2026-08-08",{"date":95,"type":39},{"date":38,"type":23},{"date":205,"type":23},"2027-03-25",{"name":45,"class":46},{"id":208,"slug":209,"hasResults":12,"nctId":210,"briefTitle":211,"officialTitle":212,"acronym":4,"eligibilityCriteria":213,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":110,"enrollmentInfo":214,"targetDuration":4,"studyType":24,"phases":216,"briefSummary":217,"conditions":218,"keywords":220,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":226,"startDateStruct":227,"completionDateStruct":229,"leadSponsor":231,"locationsCount":4},"100651470","dual-task-neuromuscular-warm-up-exercises-in-chronic-low-back-pain-100651470","NCT07761247","Dual-Task Neuromuscular Warm-Up Exercises in Chronic Low Back Pain","Immediate Effects of Dual-Task Neuromuscular Warm-Up Exercises on Balance and Proprioception in Individuals With Chronic Nonspecific Low Back Pain: A Randomized Controlled Study","Inclusion Criteria:\n\n* Diagnosed with nonspecific low back pain persisting for at least 3 months.\n* Pain intensity of ≥3 on the Visual Analog Scale (VAS).\n* Sufficient cognitive ability to understand and follow verbal and written instructions in Turkish.\n* Independent mobility sufficient to perform the tests and exercises.\n* Willingness to participate and provision of written informed consent.\n\nExclusion Criteria:\n\n* Acute disc herniation, spinal stenosis, spondylolysis, or spondylolisthesis.\n* Previous spinal surgery or a history of severe trauma affecting the spine.\n* Rheumatic diseases, malignancy, infection, or neurological diseases that may cause low back pain.\n* Sensory or motor loss in the lower extremities or deep tendon reflex loss indicating radiculopathy.\n* Known vestibular or visual system disorders.\n* Body mass index (BMI) ≥30 kg\u002Fm².\n* Pregnancy.\n* Physiotherapy\u002Frehabilitation treatment or steroid injection targeting the lumbar region within the previous 3 months.\n* Use of analgesics, muscle relaxants, or sedatives within the previous 24 hours that may affect balance or pain threshold.\n* Other orthopedic or systemic health conditions that may interfere with exercise or balance testing.",{"count":215,"type":23},40,[26],"This study aims to investigate the immediate effects of dual-task neuromuscular warm-up exercises on balance and proprioception in individuals with chronic nonspecific low back pain. Participants will be randomly assigned to either a dual-task neuromuscular warm-up exercise group or a neuromuscular warm-up exercise group. Both groups will also receive the same conventional physiotherapy program. Balance, proprioception, lumbar muscle properties, pressure pain threshold, and flexibility will be assessed before and after the intervention to determine whether adding cognitive tasks to neuromuscular warm-up exercises provides additional immediate benefits.",[219],"Low Back Pain",[221,171,222,223,224,225],"Chronic Nonspecific Low Back Pain","Neuromuscular Warm-Up","Balance","Proprioception","Postural Control",{"date":95,"type":39},{"date":228,"type":23},"2026-08-25",{"date":230,"type":23},"2027-03-10",{"name":45,"class":46},{"id":233,"slug":234,"hasResults":12,"nctId":235,"briefTitle":236,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":239,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":241,"conditions":242,"keywords":245,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":251,"startDateStruct":252,"completionDateStruct":253,"leadSponsor":255,"locationsCount":4},"100651344","turkish-version-of-the-pictorial-pain-interference-questionnaire-100651344","NCT07761208","Turkish Version of the Pictorial Pain Interference Questionnaire","Assessment of the Functional Impact of Chronic Pain: Psychometric Properties of the Turkish Version of the Pictorial Pain Interference Questionnaire","Inclusion Criteria:\n\n* Having chronic pain lasting for at least 3 months.\n* Willing to participate in the study and providing informed consent.\n* Having sufficient cognitive ability to understand the questions.\n\nExclusion Criteria:\n\n* Severe cognitive impairment (e.g., dementia) or conditions that interfere with communication.\n* Inability to cooperate due to a psychiatric disorder.\n* Neurological or serious systemic diseases that may affect the assessment.\n* Incomplete or incorrectly completed questionnaires.\n* Refusal to participate or withdrawal from the study.",{"count":240,"type":23},100,"This study aims to culturally adapt the Pictorial Pain Interference Questionnaire into Turkish and evaluate its psychometric properties in individuals with chronic pain. The study will assess the validity and reliability of the Turkish version for evaluating the functional impact of chronic pain on daily life activities. Reliability will be examined through internal consistency and test-retest reliability, while validity will be assessed by examining the relationships between the questionnaire and established pain-related assessment tools. The study will determine whether the Turkish version provides a valid, reliable, and practical instrument for assessing functional interference associated with chronic pain in Turkish-speaking individuals.",[243,244],"Pain","Pain Management",[246,247,248,249,250],"Chronic Pain","Pain Interference","Pictorial Pain Interference Questionnaire","Psychometric Properties","Turkish Version",{"date":95,"type":39},{"date":38,"type":23},{"date":254,"type":23},"2027-02-22",{"name":45,"class":46},{"id":257,"slug":258,"hasResults":12,"nctId":259,"briefTitle":260,"officialTitle":261,"acronym":4,"eligibilityCriteria":262,"healthyVolunteers":12,"sex":18,"minAge":56,"maxAge":263,"enrollmentInfo":264,"targetDuration":265,"studyType":113,"phases":4,"briefSummary":266,"conditions":267,"keywords":269,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":201,"lastUpdatePostDateStruct":275,"startDateStruct":276,"completionDateStruct":278,"leadSponsor":280,"locationsCount":47},"100646598","assessing-posture-and-rom-with-physiomaster-in-stroke-patients-100646598","NCT07690982","Assessing Posture and ROM With PhysioMaster in Stroke Patients","Validity and Reliability of the PhysioMaster in Assessing Posture and Range of Motion in Patients With Stroke","Inclusion Criteria:\n\n* Presence of hemiplegia caused solely by stroke\n* Being older than 40 years and younger than 70 years of age\n* At least 6 months have passed since the stroke\n* Ability to maintain independent standing for at least 1 minute\n* Being at stage 4 or higher according to the Brunnstrom stages of stroke recovery\n* Ability to understand and follow instructions\n* Voluntary agreement to participate in the study\n\nExclusion Criteria:\n\n* Presence of any neurological diagnosis other than stroke\n* History of orthopedic surgery within the last 6 months\n* Presence of concomitant orthopedic trauma\n* Presence of spasticity graded 3 or higher according to the Modified Ashworth Scale (MAS)","70 Years",{"count":85,"type":23},"3 Days","The smartphone application named PhysioMaster is an easy-to-use, accessible, and freely available application. Although it has been used in several previous studies, no validity or reliability study has yet been conducted in patients with stroke. Therefore, the aim of this study is to investigate the validity and reliability of the PhysioMaster smartphone application in patients with stroke.\n\nAccordingly, our hypotheses are as follows:\n\n* H0: The PhysioMaster application is not a valid and reliable measurement tool for the assessment of posture and range of motion in patients with stroke.\n* H1: The PhysioMaster application is a valid and reliable measurement tool for the assessment of posture and range of motion in patients with stroke. Participants will not take any intervention.\n\nParticipants will be evaluated in terms of posture and range of motion by using PhysioMaster, Universal Goniometer and PostureScreen Mobile. During the first-day assessment, physiotherapists A and B will complete both the PhysioMaster application assessments and all other evaluations on the same patient without seeing each other's assessment scores. In order to evaluate the test-retest reliability of the application, physiotherapist A will repeat the assessments on Physiomaster on the same patient after 3 days.",[268],"Stroke",[270,271,272,273,274],"ROM","Posture","Alignment","Tele-assessment","Smartphone application",{"date":117,"type":39},{"date":277,"type":39},"2026-07-13",{"date":279,"type":23},"2026-09-26",{"name":45,"class":46},{"id":282,"slug":283,"hasResults":12,"nctId":284,"briefTitle":285,"officialTitle":286,"acronym":4,"eligibilityCriteria":287,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":57,"enrollmentInfo":288,"targetDuration":4,"studyType":24,"phases":289,"briefSummary":290,"conditions":291,"keywords":294,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":298,"lastUpdatePostDateStruct":299,"startDateStruct":300,"completionDateStruct":301,"leadSponsor":303,"locationsCount":47},"100650218","ultrasound-guided-recto-intercostal-fascial-plane-block-in-laparoscopic-cholecystectomy-100650218","NCT07745972","Ultrasound-Guided Recto-Intercostal Fascial Plane Block in Laparoscopic Cholecystectomy","Evaluation of the Effect of Ultrasound-Guided Bilateral Recto-Intercostal Fascial Plane Block on Postoperative Pain, Opioid Consumption, and Quality of Recovery in Laparoscopic Cholecystectomy Surgery: A Prospective, Randomized, Double-Blind Controlled Clinical Study","Inclusion Criteria:\n\n* BMI \\\u003C 35 kg\u002Fm²\n* Patients with ASA scores I and II\n\nExclusion Criteria:\n\n* Patients who do not want to be included in the study\n* Psychiatric and neurological disease with blurred consciousness\n* Patients with ASA \\> 3\n* BMI \\> 35 kg\u002Fm²\n* Abnormality in coagulation parameters\n* History of allergy to local anesthetic drugs\n* Infection at the injection site",{"count":85,"type":23},[26],"The aim of the study is to reduce postoperative pain by performing rectointercostal block in L\u002FS cholecystectomy surgeries. Main goal is to provide well managed post-operative analgesia.",[292,244,293],"Analgesia","Pain, Acute Post-Operative",[295,296,297],"Cholesistectomy","Rectointercostal Plane Block","Postoperative Pain","2026-08-06",{"date":145,"type":39},{"date":298,"type":39},{"date":302,"type":23},"2026-12-31",{"name":45,"class":46},{"id":305,"slug":306,"hasResults":12,"nctId":307,"briefTitle":308,"officialTitle":309,"acronym":310,"eligibilityCriteria":311,"healthyVolunteers":12,"sex":312,"minAge":19,"maxAge":4,"enrollmentInfo":313,"targetDuration":4,"studyType":24,"phases":314,"briefSummary":315,"conditions":316,"keywords":318,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":326,"lastUpdatePostDateStruct":327,"startDateStruct":329,"completionDateStruct":330,"leadSponsor":331,"locationsCount":47},"100646525","mobile-health-support-before-oocyte-pick-up-in-infertile-women-100646525","NCT07690969","Mobile Health Support Before Oocyte Pick-Up in Infertile Women","Effect of a Structured Mobile Health Application on Medication Adherence and Quality of Life in Infertile Women Before Oocyte Pick-Up","OPUCARE","Inclusion Criteria:\n\n* Female participants aged 18 years and older\n* Diagnosed with primary infertility\n* Scheduled to undergo oocyte pick-up (OPU) for the first time\n* Newly starting medication treatment during the period before OPU\n* Own a smartphone and are able to use basic mobile applications\n* Willing to participate in the study and provide written informed consent\n\nExclusion Criteria:\n\n* Diagnosis of secondary infertility\n* Presence of a serious chronic disease that may significantly affect medication adherence and\u002For quality of life\n* Presence of an active serious psychiatric disorder\n* Cognitive or physical limitation that prevents use of the mobile application","FEMALE",{"count":85,"type":23},[26],"This study aims to evaluate the effect of the OPUCARE system, a structured mobile health application used before oocyte pick-up (OPU), on medication adherence and quality of life in infertile women. The study will also examine the possible effect of the intervention on state anxiety.\n\nParticipants will be randomly assigned to either the intervention group or the control group. The intervention group will receive routine clinical care plus the OPUCARE system. The control group will receive routine clinical care and standard written and verbal information provided by the clinic, without mobile health application support.\n\nThe intervention period will last approximately 2 weeks, from the start of medication treatment until oocyte pick-up. Medication adherence, quality of life, and state anxiety will be assessed before and after the intervention period.",[317],"Female İnfertility",[310,319,320,321,322,323,324,325],"Oocyte Pick-Up","Medication Adherence","State Anxiety","Assisted Reproductive Technology","Randomized Controlled Trial","Mobile Health Application","Fertility-Related Quality of Life","2026-07-29",{"date":328,"type":39},"2026-07-30",{"date":70,"type":23},{"date":43,"type":23},{"name":45,"class":46},{"id":333,"slug":334,"hasResults":12,"nctId":335,"briefTitle":336,"officialTitle":337,"acronym":4,"eligibilityCriteria":338,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":339,"targetDuration":4,"studyType":24,"phases":341,"briefSummary":342,"conditions":343,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":353,"locationsCount":47},"100648519","comparison-of-social-media-based-and-online-training-in-grief-counseling-education-100648519","NCT07723170","Comparison of Social Media-Based and Online Training in Grief Counseling Education","Comparison of Social Media-Based and Online Training in Grief Counseling Education: A Randomized Controlled Head-to-Head Study","Inclusion Criteria:\n\n* Midwives or nurses currently working in perinatal care settings in Türkiye.\n* Aged 18 years or older.\n* Own a smartphone and have regular internet access.\n* Able to actively use Instagram and Zoom.\n* Provide informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Previous training in perinatal grief counseling.\n* Failure to participate regularly in the educational intervention.\n* Failure to complete the study assessments.",{"count":340,"type":23},72,[26],"This randomized trial aims to compare the effectiveness of two digital educational approaches for perinatal grief counseling training among midwives and nurses working in perinatal care settings in Türkiye: a social media-based education program delivered through Instagram and an online education program delivered through Zoom. Both groups will receive the same six-module perinatal grief counseling education content, but through different delivery methods.\n\nParticipants will be randomly assigned to one of the two study groups. Outcomes will be assessed before the intervention, immediately after completion of the 6-week training program, and 4 weeks after the intervention. The study will evaluate changes in participants' competency and confidence in providing perinatal grief care and compare the sustainability of learning outcomes between the two digital education models.",[344,345,346],"Perinatal Grief","Perinatal Loss","Bereavement","2026-07-23",{"date":349,"type":39},"2026-07-24",{"date":351,"type":23},"2026-07-27",{"date":43,"type":23},{"name":45,"class":46},{"id":355,"slug":356,"hasResults":12,"nctId":357,"briefTitle":358,"officialTitle":359,"acronym":4,"eligibilityCriteria":360,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":361,"enrollmentInfo":362,"targetDuration":4,"studyType":24,"phases":363,"briefSummary":364,"conditions":365,"keywords":367,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":369,"lastUpdatePostDateStruct":370,"startDateStruct":371,"completionDateStruct":373,"leadSponsor":375,"locationsCount":47},"100648558","comparison-between-dynamic-neuromuscular-stabilization-breathing-and-manual-therapy-on-forward-head-posture-in-university-students-100648558","NCT07721389","Comparison Between Dynamic Neuromuscular Stabilization Breathing and Manual Therapy on Forward Head Posture in University Students","The Effects of Dynamic Neuromuscular Stabilization Breathing and Manual Therapy on Forward Head Posture in University Students: A Randomized Controlled Trial","Inclusion Criteria:\n\nUniversity student aged 18 to 28 years\n\nPresence of forward head posture confirmed by photogrammetric assessment\n\nMild to moderate cervical pain (VAS score between 0 and 6)\n\nVoluntary agreement to participate in the study\n\nExclusion Criteria:\n\nHistory of cervical spine surgery\n\nPresence of neurological disorders\n\nDiagnosis of cervical disc herniation\n\nSevere musculoskeletal pain (VAS ≥ 7)","28 Years",{"count":85,"type":23},[26],"Forward Head Posture (FHP) is a common postural dysfunction characterized by the anterior displacement of the head relative to the shoulders, leading to cervical spine misalignment, increased muscle strain, and neck pain. It is highly prevalent in university students (63-66%), largely due to prolonged sedentary behaviors and the use of smartphones, laptops, and tablets in poor ergonomic postures .\n\nThis randomized controlled trial aims to evaluate the effectiveness of three intervention strategies for managing FHP in university students:\n\nDynamic Neuromuscular Stabilization (DNS) Breathing + Conventional Exercises: DNS breathing will emphasize diaphragmatic activation and postural stabilization, combined with stretching, strengthening, and postural education.\n\nMyofascial Release (MFR) + Conventional Exercises: Suboccipital MFR to release fascial tension, combined with the same conventional exercise program.\n\nConventional Exercises Alone (Control Group): A standard rehabilitation protocol of stretching, strengthening, and postural correction.\n\nAll interventions will be delivered three times per week for six weeks, with each session lasting 45 minutes.\n\nAssessments will be conducted at baseline, week 4, and week 6:\n\nCraniovertebral Angle (CVA) and Forward Shoulder Angle (FSA) measured using smartphone photographic analysis.\n\nWall Test to assess forward head and rounded shoulder posture.\n\nVisual Analog Scale (VAS) to measure subjective pain intensity.\n\nSF-36 Health Survey to evaluate quality of life across eight health domains.\n\nThe study will compare the relative effectiveness of DNS breathing and MFR, each combined with conventional therapy, against conventional therapy alone. Findings are expected to contribute to evidence-based postural rehabilitation, particularly for young adults with sedentary lifestyles.",[366],"Forward Head Posture",[368],"Forward Head Posture, Dynamic Neuromuscular Stabilization, Myofascial Release, Conventional Therapy, Neck Pain, Cervical Spine","2026-07-20",{"date":347,"type":39},{"date":372,"type":39},"2025-05-16",{"date":374,"type":23},"2026-07-15",{"name":45,"class":46},{"id":377,"slug":378,"hasResults":12,"nctId":379,"briefTitle":380,"officialTitle":381,"acronym":4,"eligibilityCriteria":382,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":383,"enrollmentInfo":384,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":386,"conditions":387,"keywords":389,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":395,"lastUpdatePostDateStruct":396,"startDateStruct":398,"completionDateStruct":400,"leadSponsor":401,"locationsCount":47},"100640854","cervical-position-sense-core-stability-and-postural-balance-in-university-students-with-upper-crossed-syndrome-100640854","NCT07577492","Cervical Position Sense, Core Stability, and Postural Balance in University Students With Upper Crossed Syndrome","Relationship Between Cervical Position Sense, Core Stabilization, and Postural Balance in University Students Aged 18 to 30 Years With Upper Crossed Syndrome","Inclusion Criteria:\n\n* University students aged 18-30 years.\n* Diagnosis of Upper Crossed Syndrome (UCS) confirmed by postural assessment.\n* Forward Head Posture with Craniovertebral Angle (CVA) less than 49 degrees.\n* Rounded Shoulder Posture greater than 2.5 cm.\n* Presence of chronic neck pain.\n* Impaired cervical position sense.\n\nExclusion Criteria:\n\n* History of cervical spine surgery.\n* Neurological disorders (e.g., stroke, multiple sclerosis, Parkinson's disease).\n* Acute musculoskeletal injury to the neck, back, or upper extremities within the past 3 months.\n* Previous traumatic injuries to the neck or back.\n* Any diagnosed vestibular or balance disorder.\n* Visual impairment that affects balance.\n* Pregnancy.\n* Participation in another interventional clinical trial within the past 30 days.","30 Years",{"count":385,"type":23},48,"This study aims to investigate the relationship between cervical position sense, core stabilization, and postural balance in university students aged 18-30 years with Upper Crossed Syndrome (UCS). Upper Crossed Syndrome is a common musculoskeletal disorder characterized by muscle imbalance, including weakness of the deep cervical flexors, middle and lower trapezius, rhomboids, and serratus anterior, along with tightness of the upper trapezius, levator scapulae, sternocleidomastoid, and pectoralis major and minor. This condition frequently affects university students due to prolonged sitting, extensive computer use, and poor posture. While previous research has focused on discrete components of UCS such as posture correction or pain management, the combined effects of cervical proprioception, core stability, and postural balance remain poorly understood. A total of 48 participants will be enrolled and divided into two equal groups: 24 students diagnosed with Upper Crossed Syndrome and 24 healthy students as a control group. Assessments include cervical joint position error testing, core stabilization endurance tests (Unilateral Hip Bridge Endurance Test and Sahrmann Five-Level Core Stability Test), static balance evaluation using the Balance Error Scoring System (BESS), and dynamic balance assessment using the Y-Balance Test. Pain intensity will be measured using the Visual Analog Scale (VAS). This study will help identify neuromuscular and sensory mechanisms underlying these parameters and support evidence-based rehabilitation techniques to improve postural alignment, reduce musculoskeletal dysfunction, and enhance overall functional performance in this population.",[388],"Upper Crossed Syndrome",[390,391,392,31,393,394],"neck pain","cervical position sense","upper crossed syndrome","postural control","proprioception","2026-07-12",{"date":397,"type":39},"2026-07-14",{"date":399,"type":39},"2026-04-20",{"date":328,"type":23},{"name":45,"class":46},{"id":403,"slug":404,"hasResults":12,"nctId":405,"briefTitle":406,"officialTitle":407,"acronym":408,"eligibilityCriteria":409,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":410,"targetDuration":412,"studyType":113,"phases":4,"briefSummary":413,"conditions":414,"keywords":418,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":423,"lastUpdatePostDateStruct":424,"startDateStruct":426,"completionDateStruct":427,"leadSponsor":429,"locationsCount":47},"100646553","preoperative-versus-postoperative-interscalene-block-in-arthroscopic-rotator-cuff-repair-100646553","NCT07689448","Preoperative Versus Postoperative Interscalene Block in Arthroscopic Rotator Cuff Repair","Pre-Procedure Versus Post-Procedure Administration of Interscalene Block in Arthroscopic Rotator Cuff Repair: Effects on Early Pain Control and Functional Outcomes","ISB-ARCR","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Patients undergoing primary arthroscopic rotator cuff repair.\n* Presence of a repairable small-, medium-, or large-sized rotator cuff tear confirmed by clinical and imaging evaluation.\n* Receipt of an ultrasound-guided interscalene nerve block as part of perioperative pain management.\n* Ability to provide informed consent and comply with study follow-up requirements.\n\nExclusion Criteria:\n\n* Irreparable rotator cuff tears.\n* Partial-thickness rotator cuff tears not requiring repair.\n* Revision rotator cuff repair procedures.\n* Concomitant shoulder procedures that could substantially influence postoperative pain or functional outcomes (e.g., shoulder arthroplasty, fracture fixation).\n* Previous surgery on the affected shoulder.\n* Contraindications to interscalene nerve block, including local anesthetic allergy, infection at the injection site, or severe neurologic disease affecting the brachial plexus.\n* Chronic opioid use or opioid dependence before surgery.\n* Inability to complete study questionnaires or follow the postoperative rehabilitation protocol.\n* Missing baseline or follow-up data required for outcome assessment.",{"count":411,"type":23},42,"6 Months","This study is evaluating whether the timing of an interscalene nerve block affects pain control and recovery after arthroscopic rotator cuff repair surgery.\n\nAn interscalene block is commonly used to reduce pain after shoulder surgery. However, it is not known whether administering the block before surgery or after surgery provides better outcomes. Participants undergoing arthroscopic rotator cuff repair are assigned to receive the interscalene block either before the surgical incision or after completion of the procedure.\n\nThe study compares postoperative pain levels, opioid medication use, length of hospital stay, and ultrasound imaging quality during block administration between the two groups. Functional recovery is also assessed using patient-reported outcome measures during follow-up.\n\nThe investigators hypothesize that administration of the interscalene block before surgery may provide superior early pain control and reduce postoperative opioid requirements while maintaining similar functional outcomes compared with administration after surgery.",[415,416,417],"Rotator Cuff Tear Repair","Interscalene Blocks","Rotator Cuff Tears",[417,419,420,421,297,422,244],"Arthroscopic Rotator Cuff Repair","Interscalene Nerve Block","Regional Anesthesia","Preemptive Analgesia","2026-07-07",{"date":425,"type":39},"2026-07-08",{"date":277,"type":23},{"date":428,"type":23},"2026-10-20",{"name":45,"class":46},{"id":431,"slug":432,"hasResults":12,"nctId":433,"briefTitle":434,"officialTitle":435,"acronym":4,"eligibilityCriteria":436,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":437,"targetDuration":136,"studyType":113,"phases":4,"briefSummary":438,"conditions":439,"keywords":440,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":444,"lastUpdatePostDateStruct":445,"startDateStruct":447,"completionDateStruct":449,"leadSponsor":451,"locationsCount":47},"100643875","interoception-in-stroke-100643875","NCT07669246","Interoception in Stroke","Association of Interoception With Somatosensory Function, Proprioception, and Balance in Patients With Hemiplegia","Inclusion Criteria:\n\n* Presence of hemiplegia due to a physician-diagnosed stroke,\n* At least 6 months have passed since the stroke,\n* Voluntary agreement to participate in the study.\n\nExclusion Criteria:\n\n* History of traumatic brain injury, brain tumor, meningitis, or secondary neurological disease,\n* Having experienced a cardiovascular event or any acute medical condition within the last 3 months,\n* Insufficient visual or auditory ability to understand the questionnaires and tests.",{"count":85,"type":23},"This study aims to examine the associations of interoceptive awareness and interoceptive accuracy with plantar superficial sensory threshold, knee joint proprioception, pain intensity, and dynamic balance performance in cognitively intact individuals with chronic hemiplegia.\n\nHypotheses are:\n\n* H0: There is no significant relationship between interoception and light touch, proprioception, pain, or dynamic balance performance in cognitively intact individuals with chronic hemiplegia.\n* H1: There is a significant relationship between interoception and light touch, proprioception, pain, or dynamic balance performance in cognitively intact individuals with chronic hemiplegia All participants will undergo a single assessment session and will not be invited for any treatment or follow-up evaluation. Participants will not take any intervention.",[268],[441,442,443],"Plantar sensation","Joint position sense","Fear of falling","2026-07-01",{"date":446,"type":39},"2026-07-02",{"date":448,"type":23},"2026-06-20",{"date":450,"type":23},"2026-12-25",{"name":45,"class":46},{"id":453,"slug":454,"hasResults":12,"nctId":455,"briefTitle":456,"officialTitle":457,"acronym":4,"eligibilityCriteria":458,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":56,"enrollmentInfo":459,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":461,"conditions":462,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":466,"lastUpdatePostDateStruct":467,"startDateStruct":469,"completionDateStruct":471,"leadSponsor":473,"locationsCount":4},"100639763","motion-sickness-severity-and-sensorimotor-performance-100639763","NCT07619469","Motion Sickness Severity and Sensorimotor Performance","The Relationship of Balance, Proprioception, Coordination, and Reaction Time Measurements With Motion Sickness Severity in Individuals With Motion Sickness: A Cross-Sectional Study","Inclusion Criteria:\n\n* Individuals aged between 18 and 40 years.\n* Diagnosed with motion sickness according to the Motion Sickness -Susceptibility Questionnaire Short Form (MSSQ-SF).\n* Normal hearing acuity.\n* No history of acute or chronic vestibular disease, other than motion sickness.\n* Normal or corrected-to-normal vision.\n* Adequate physical capability to fully perform the measurement protocols, including balance, proprioception, coordination, and reaction time tests.\n\nExclusion Criteria:\n\n* Presence of any physical or orthopedic problem that could interfere with testing.\n* History of acute or chronic instability, unsteadiness, or vertigo.\n* Severe visual impairment.\n* History of prior ear surgery.\n* Presence of any neurological condition or disorder.\n* History of migraines.\n* Current use of medications that could affect balance or vestibular function (e.g., vestibular suppressants, sedatives).\n* Use of alcohol or psychoactive substances within the last 48 hours prior to testing.",{"count":460,"type":23},41,"Background: Motion sickness (MS) is a common syndrome characterized by autonomic and behavioral symptoms, such as nausea and dizziness, resulting from exposure to motion stimuli. Its pathophysiology is closely linked to sensory conflict and postural instability theories. While previous studies suggest that postural control, proprioception, and reaction times are affected in individuals susceptible to MS, there is a lack of comprehensive, comparative research evaluating all these parameters concurrently within the same cohort using standardized methods. Objective: This study aims to systematically measure balance, proprioceptive sensitivity, coordination, and reaction time parameters, and quantitatively analyze their relationship with motion sickness severity. Methodology: In this prospective, cross-sectional study, at least 41 participants aged 18-40 with motion sickness will be recruited. Participants will undergo motion sickness susceptibility and severity grading using the Motion Sickness Susceptibility Questionnaire Short Form (MSSQ-SF) and the Graybiel Scale. Objective assessments will include static and dynamic balance testing (ProKin®), knee joint position sense (Clinometer app), manual dexterity and dynamic balance coordination (Nine-Hole Peg Test, Tandem Walk, Romberg Test), and upper\u002Flower extremity reaction time measurements (BlazePod system).",[463,464,465],"Motion Sickness","Somatosensory Disorders","Dizziness","2026-06-23",{"date":468,"type":39},"2026-06-26",{"date":470,"type":23},"2026-06-01",{"date":472,"type":23},"2026-08-05",{"name":45,"class":46},{"id":475,"slug":476,"hasResults":12,"nctId":477,"briefTitle":478,"officialTitle":479,"acronym":4,"eligibilityCriteria":480,"healthyVolunteers":17,"sex":481,"minAge":482,"maxAge":19,"enrollmentInfo":483,"targetDuration":4,"studyType":24,"phases":485,"briefSummary":486,"conditions":487,"keywords":491,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":498,"lastUpdatePostDateStruct":499,"startDateStruct":501,"completionDateStruct":503,"leadSponsor":505,"locationsCount":47},"100641050","effects-of-core-and-inspiratory-muscle-training-on-muscle-oxygenation-and-athletic-performance-n-young-soccer-players-100641050","NCT07657065","Effects of Core and Inspiratory Muscle Training on Muscle Oxygenation and Athletic Performance İn Young Soccer Players","Effects of Core and Inspiratory Muscle Training On Muscle Oxygenation and Athletic Performance İn Young Soccer Players","Inclusion Criteria:\n\n* Being between 15 and 18 years of age.\n* Being a male soccer player.\n* Actively and regularly participating in trainings at Alagöz Soccer Club.\n* Having participated in regular soccer training for at least the last 6 months.\n* Being able to continue routine trainings throughout the study period.\n* Being fully informed about the research.\n* Having obtained voluntary informed consent, and parental\u002Fguardian consent for participants under 18 years of age.\n* Having the cognitive and physical capacity to understand and fulfill the specific test and exercise instructions.\n\nExclusion Criteria:\n\n* Having a history of lower extremity, trunk-core, or athletic performance-limiting injury within the last 6 months.\n* Having undergone orthopedic lower extremity or spine surgery within the last 1 year.\n* Having active musculoskeletal pain or any orthopedic\u002Fneurological condition that prevents exercise.\n* Having any health condition that prevents the safe execution of balance, sprint, agility, jump, or core endurance tests.\n* Having asthma, chronic respiratory system diseases, exercise-induced bronchospasm, cardiovascular disease, or a physician-imposed restriction on high-intensity exercise that could affect respiratory muscle or exercise testing.\n* Having open wounds, infections, or severe skin sensitivity that prevents the application of sensors placed on the skin.\n* Currently participating in another structured respiratory muscle training or structured core exercise program that could affect the study results.\n* Having a body mass index (BMI) of 30 kg\u002Fm² or above.\n* Being deemed unsuitable for the study by the researcher due to safety concerns.\n* Withdrawal from the study at the request of the participant or their parent\u002Fguardian.\n* Missing two consecutive exercise sessions or having an insufficient overall attendance rate.\n* Developing an exercise-preventing injury or illness during the study period.\n* Occurrence of any safety risk during testing or exercise sessions.\n* Non-compliance with the study protocol.\n* Starting another additional exercise program during the study.\n* Technical inability to obtain reliable measurement data.","MALE","15 Years",{"count":484,"type":23},54,[26],"The purpose of this randomized controlled trial is to investigate the effects of core training and inspiratory muscle training (IMT) on muscle oxygenation and athletic performance in youth male soccer players aged 15-18. A total of 54 healthy soccer players will be included and randomly assigned into three equal groups: the Control Group, the Core Training Group, and the Core Training + IMT Group.\n\nAll interventions will be implemented for 8 weeks in addition to routine soccer training sessions. Assessments will be performed at baseline (Week 0), mid-intervention (Week 4), and post-intervention (Week 8). The primary outcome measures of the study are aerobic capacity assessed by the Yo-Yo Intermittent Recovery Test Level 1 and muscle oxygenation parameters monitored via near-infrared spectroscopy (NIRS) using a MOXY monitor. Secondary outcome measures include sprint performance, agility, dynamic balance, core muscle strength and endurance, inspiratory muscle strength, lower extremity explosive power, and soccer-specific technical performance tests.\n\nOverall, this study aims to reveal the combined effects of core training and inspiratory muscle training on muscle oxygenation, respiratory functions, aerobic capacity, and soccer performance, while explaining the underlying physiological mechanisms in youth athletes.",[488,489,490],"Athletic Performance","Muscle Oxygenation","Respiratory Function",[492,493,494,495,496,497],"Youth Soccer","Core Training","Inspiratory Muscle Training","Near-Infrared Spectroscopy","Aerobic Capacity","Diaphragm","2026-06-17",{"date":500,"type":39},"2026-06-18",{"date":502,"type":23},"2026-08",{"date":504,"type":23},"2027-12",{"name":45,"class":46},{"id":507,"slug":508,"hasResults":12,"nctId":509,"briefTitle":510,"officialTitle":511,"acronym":4,"eligibilityCriteria":512,"healthyVolunteers":12,"sex":312,"minAge":19,"maxAge":263,"enrollmentInfo":513,"targetDuration":4,"studyType":24,"phases":514,"briefSummary":515,"conditions":516,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":519,"lastUpdatePostDateStruct":520,"startDateStruct":522,"completionDateStruct":524,"leadSponsor":526,"locationsCount":47},"100630093","effectiveness-of-thoracoabdominal-nerve-block-m-tapa-on-postoperative-pain-relief-in-laparoscopic-hysterectomy-100630093","NCT07483190","Effectiveness of Thoracoabdominal Nerve Block (M-TAPA) on Postoperative Pain Relief in Laparoscopic Hysterectomy","Effectiveness of Modified-Thoracoabdominal Nerve Block With Perichondrial Approach (M-TAPA) on Postoperative Pain Relief in Laparoscopic Hysterectomy Surgery: A Prospective, Randomized, Double-Blind, Controlled Study","Inclusion Criteria:\n\n* Aged between 18 and 70 years\n* ASA (American Society of Anesthesiologists) physical status I, II, or III\n* Scheduled for elective laparoscopic hysterectomy\n* Voluntary participation with signed informed consent\n\nExclusion Criteria:\n\n* Hepatic or renal disease.\n* Coagulation disorders.\n* Uncontrolled cardiovascular or respiratory diseases.\n* Psychiatric disorders.\n* History of allergy to local anesthetics.\n* History of alcoholism, drug or substance abuse.\n* Body Mass Index (BMI) greater than 35 kg\u002Fm2\n* Refusal of the regional block procedure",{"count":85,"type":23},[26],"This study aims to investigate the effectiveness of a specific regional anesthesia technique, the Modified-Thoracoabdominal Nerve Block through a Perichondrial Approach (M-TAPA), on reducing pain after laparoscopic hysterectomy surgery. Hysterectomy is a common major surgical procedure, and managing postoperative pain is crucial for patient comfort and faster recovery.\n\nParticipants will be randomly assigned to one of two groups:\n\nThe M-TAPA Group: Patients will receive the nerve block using a local anesthetic (bupivacaine) before the surgery begins.\n\nThe Control Group: Patients will receive standard postoperative pain management without the nerve block.\n\nThe primary goal is to determine if the M-TAPA block reduces the total amount of opioid (morphine) used by patients in the first 24 hours after surgery. The researchers will also evaluate pain scores (NRS), the time until the first request for additional pain medication, patient satisfaction, and any side effects like nausea or vomiting",[297,517,518],"Hysterectomy","Plane Blocks","2026-06-12",{"date":521,"type":39},"2026-06-16",{"date":523,"type":39},"2026-06-09",{"date":525,"type":23},"2026-11-15",{"name":45,"class":46},{"id":528,"slug":529,"hasResults":12,"nctId":530,"briefTitle":531,"officialTitle":532,"acronym":4,"eligibilityCriteria":533,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":383,"enrollmentInfo":534,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":536,"conditions":537,"keywords":539,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":544,"lastUpdatePostDateStruct":545,"startDateStruct":546,"completionDateStruct":548,"leadSponsor":549,"locationsCount":47},"100632999","functional-capacity-subjective-dyspnea-and-fatigue-in-smokers-100632999","NCT07520981","Functional Capacity, Subjective Dyspnea and Fatigue in Smokers","Relationship Between Functional Capacity and Subjective Dyspnea and Fatigue in Young Adult Smokers","Inclusion Criteria:\n\n* Being between 18 and 30 years of age.\n* Being actively enrolled in university.\n* Being a current smoker,\n* Having been a regular smoker for at least the last 6 months,\n* Having a daily cigarette consumption of ≥1 cigarette\u002Fday.\n* Volunteering to participate in the study and providing written informed consent.\n* Having the cognitive and physical capacity to understand and complete the tests to be administered.\n\nExclusion Criteria:\n\n* Having a diagnosed chronic respiratory disease (asthma, COPD, bronchiectasis, interstitial lung disease, etc.),\n* Having had an upper or lower respiratory tract infection within the last 4 weeks. Having a diagnosed heart disease (coronary artery disease, heart failure, arrhythmia, etc.),\n* Having a history of uncontrolled hypertension.\n* Having orthopedic problems affecting walking, sitting\u002Fstanding, or balance,\n* Having a history of lower extremity surgery or serious injury within the last 6 months.\n* Having a history of neurological disease affecting balance, coordination, or motor control (stroke, multiple sclerosis, epilepsy, etc.).\n* Having a systemic disease that may prevent participation in exercise (uncontrolled diabetes, severe anemia, etc.),\n* Being pregnant or within the first 6 months postpartum.\n* Having conditions that may endanger the participant's safety during functional tests, o Refusal to complete the tests or inability to cooperate during the evaluation.",{"count":535,"type":23},107,"Smoking remains a significant public health problem among the young adult population. Epidemiological studies in Turkey show a steadily decreasing age of smoking initiation and a remarkably high rate of smoking among university-aged individuals. Exposure to secondhand smoke is known to have negative effects on the respiratory system, cardiovascular system, and peripheral muscle function.\n\nImpaired lung ventilation, reduced gas exchange, and insufficient oxygen transport due to smoking can lead to decreased exercise tolerance, premature fatigue, and increased perception of exertional dyspnea. These effects can manifest as a decrease in functional capacity even before the development of a clinically significant respiratory disease.\n\nFunctional capacity is an important indicator reflecting an individual's ability to perform daily living activities and is frequently assessed in clinical research using submaximal exercise tests. The 6-Minute Walk Test is a widely used, valid, and reliable test for assessing cardiorespiratory endurance and overall functional status. Similarly, the 1-Minute Sit-Stand Test is recommended as a practical and applicable method for evaluating lower extremity muscle endurance and functional performance.\n\nDyspnea is a multidimensional symptom reflecting an individual's subjective perception of respiratory discomfort and is assessed using scales such as the Modified Medical Research Council and the Borg Dyspnea Scale. The Turkish Thoracic Society's dyspnea assessment reports indicate that exertional dyspnea may increase in smokers even if respiratory function tests are within normal limits.\n\nFatigue, on the other hand, is a significant symptom that negatively affects an individual's daily living activities and physical functionality, arising from inflammatory processes, impaired oxygenation, and decreased physical activity levels associated with smoking. The Fatigue Severity Scale is a validated and reliable scale for assessing the impact of fatigue on an individual's physical and social life.\n\nWhile studies in the literature examine the effects of smoking on respiratory function and exercise capacity, studies that address the relationship between functional capacity and subjective dyspnea and fatigue in young adult smokers are limited. In particular, evaluating functional test results such as the 6-Minute Walk Test and the 1-Minute Sit-Stand Test together with dyspnea and fatigue perception will contribute to the early identification of subclinical functional effects.\n\nThe aim of this study is to examine the relationships between functional capacity (6-Minute Walk Test, 1-Minute Sit-Stand Test, and Timed Up and Go Test) and subjective dyspnea (Modified Medical Research Council Scale - mMRC) and fatigue level (Fatigue Severity Scale) in young adult smokers aged 18-30 years. The findings of this study are expected to draw attention to the functional effects of smoking in young adults, contribute to the development of preventive health approaches, and facilitate the planning of physiotherapy-based assessment and intervention programs.",[538],"Smoking",[540,541,542,543],"functional capacity","subjectice dyspnea","fatigue","young adult smoker","2026-06-07",{"date":523,"type":39},{"date":547,"type":39},"2026-04-15",{"date":328,"type":23},{"name":45,"class":46},{"id":551,"slug":552,"hasResults":12,"nctId":553,"briefTitle":554,"officialTitle":555,"acronym":4,"eligibilityCriteria":556,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":557,"enrollmentInfo":558,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":559,"conditions":560,"keywords":562,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":566,"lastUpdatePostDateStruct":567,"startDateStruct":569,"completionDateStruct":571,"leadSponsor":572,"locationsCount":47},"100637027","pain-and-upper-extremity-function-in-smartphone-and-digital-game-addiction-100637027","NCT07573345","Pain and Upper Extremity Function in Smartphone and Digital Game Addiction","The Effects of Smartphone and Digital Game Addiction on Pain and Upper Extremity Function: A Comparative Study","Inclusion Criteria:\n\n* Being between 18-45 years old\n* Volunteering to participate in the study\n\nExclusion Criteria:\n\n* Individuals who have undergone major surgery or trauma related to the musculoskeletal system, primarily the upper extremities and trunk\n* Individuals with neurological diseases\n* Individuals with active rheumatic diseases\n* Individuals with systemic diseases (diabetes, hypothyroidism, infection, malignancy, etc.)\n* Individuals with serious psychological problems (scoring 30 or higher on the BDE)\n* Individuals with contraindications to the assessment methods (acute inflammations, viral and bacterial infections, infectious diseases, fever, deep vein thrombosis, active malignant disease, aneurysms)\n* Obesity (BMI ≥ 30 kg\u002Fm2)","45 Years",{"count":85,"type":23},"With the expansion of technology-based applications, daily phone use has increased significantly. According to a 2020 study, phone use habits among young adults aged 18-34 increased by 38.1%, and the time spent on the phone exceeding one hour increased by 68%. Currently, there is no clear definition of smartphone \"addiction\" or smartphone use, but like other types of addiction, it refers to the effort to control smartphone habits that cause problems or distress in daily life. Recent studies have reported a correlation between excessive screen use and individuals' mental and physical health. Excessive use of phones and video games causes many negative effects, including attention deficit, inability to enjoy life, hyperactivity, depression, anxiety, pain, and functional loss.\n\nVideo games are a type of game played through an audiovisual device and can be story-based. While many video games improve players' critical thinking, strategic planning, and problem-solving skills, they can also cause musculoskeletal problems due to the long hours spent at the desk and the repetitive movements involved.\n\nThe human spine is a kinematic chain with all joints interconnected; this means that changes in other body parts, such as the increased head tilt while texting on a smartphone, can have significant effects on the entire spine. A 2023 study showed an increase in spinal curvature, particularly in the cervical region, as smartphone use time increased. A study in Korea linked smartphone use to increased pain in the neck, wrists, hands, shoulders, and back. Another significant problem for smartphone users and video game players is \"text neck,\" which occurs from prolonged screen time. This causes tension in the cervical spine, leading to neck pain and stiffness.\n\nSmartphone addiction leads to hand-related problems, primarily hand and wrist pain. Furthermore, excessive use of smartphones, game controllers, and joysticks can lead to repetitive strain injuries such as carpal tunnel syndrome. Prolonged phone use, repetitive movements, and uncomfortable hand positions during use cause inflammation of the muscles and tendons in the hands and wrists, leading to swelling, pain, and loss of function in these joints. Video games are played using devices such as computers, consoles, handheld computers, and smartphones. The continuous, repetitive, and uninterrupted movements performed while using these devices can lead to musculoskeletal disorders, particularly in the upper extremities. Prolonged playing of these games results in musculoskeletal problems such as carpal tunnel syndrome and tendinitis. Extensive studies have shown that individuals' pain and symptoms worsen after prolonged gaming sessions. However, to date, there has been no study comparing smartphone addicts and video game players.\n\nThe aim of this research is to compare individuals with smartphone addiction, those who play video games for extended periods, and those without these habits in terms of pain, posture, and upper extremity function.",[561],"Addiction",[563,243,564,565],"upper extremity performance","Smartphone","Game","2026-05-24",{"date":568,"type":39},"2026-05-27",{"date":570,"type":39},"2026-05-01",{"date":374,"type":23},{"name":45,"class":46},{"id":574,"slug":575,"hasResults":12,"nctId":576,"briefTitle":577,"officialTitle":578,"acronym":4,"eligibilityCriteria":579,"healthyVolunteers":17,"sex":481,"minAge":19,"maxAge":20,"enrollmentInfo":580,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":582,"conditions":583,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":586,"lastUpdatePostDateStruct":587,"startDateStruct":588,"completionDateStruct":590,"leadSponsor":592,"locationsCount":4},"100637638","respiratory-function-and-athletic-performance-in-professional-soccer-players-100637638","NCT07617116","Respiratory Function and Athletic Performance in Professional Soccer Players","Association Between Respiratory Function and Athletic Performance Parameters in Professional Soccer Players: A Cross-Sectional Study","Inclusion Criteria:\n\n* Participants will be actively competing, licensed professional soccer players. -Participants will be engaged in regular, team-based training and competitive match schedules.\n* Participants will voluntarily provide written informed consent before any study-related physical performance assessments are conducted.\n\nExclusion Criteria:\n\n* Participants will be excluded if they present with an acute upper or lower respiratory tract infection that could potentially affect pulmonary function or maximal respiratory muscle performance.\n* Participants will be excluded if they have a documented history of major cardiothoracic surgery.\n* Participants will be excluded if they have any diagnosed respiratory and\u002For cardiovascular disorder associated with dyspnea or impaired pulmonary mechanics.\n* Participants will be excluded if they present with any condition that elevates clinical risk during maximal inspiratory and expiratory pressure assessments.\n* Participants will be excluded if they have sustained an acute musculoskeletal injury within the preceding 6 weeks that could compromise maximal physical exertion during sport-specific performance testing.",{"count":581,"type":23},31,"This prospective observational study aims to investigate the relationship between respiratory function and multidimensional athletic performance parameters in professional soccer players. The primary hypothesis of the study is that soccer players with enhanced respiratory function and superior respiratory muscle strength will exhibit optimized motor performance outcomes and shorter (faster) reactive reaction times. Investigators will evaluate respiratory muscle strength, spirometric pulmonary functions, dynamic balance, core and abdominal endurance, and reactive visuomotor reaction times during a single testing session within the competitive season.",[490,584,488,585],"Respiratory Muscle Strength","Reaction Time","2026-05-23",{"date":470,"type":39},{"date":589,"type":23},"2026-05-25",{"date":591,"type":23},"2026-07-10",{"name":45,"class":46},{"id":594,"slug":595,"hasResults":12,"nctId":596,"briefTitle":597,"officialTitle":598,"acronym":4,"eligibilityCriteria":599,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":110,"enrollmentInfo":600,"targetDuration":4,"studyType":24,"phases":602,"briefSummary":603,"conditions":604,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":606,"lastUpdatePostDateStruct":607,"startDateStruct":609,"completionDateStruct":611,"leadSponsor":613,"locationsCount":4},"100637903","sciatic-neural-mobilization-in-lumbar-related-leg-pain-100637903","NCT07588919","Sciatic Neural Mobilization in Lumbar-Related Leg Pain","Immediate Effects of Sciatic Neural Mobilization on Balance and Proprioception in Patients With Low Back Pain and Radiating Leg Pain: A Prospective Randomized Clinical Trial","Inclusion Criteria:\n\n* Having low back pain accompanied by radiating leg pain (radicular or pseudoradicular pain) for at least 3 weeks\n* Demonstration of peripheral nerve sensitivity through clinical evaluation and neurodynamic tests\n* Pain intensity of at least 3 on the Visual Analog Scale (VAS)\n* Ability to understand verbal and written Turkish instructions\n* Providing signed informed consent\n\nExclusion Criteria:\n\n* Presence of surgical indication due to acute disc herniation or advanced lumbar disc pathology\n* History of spinal surgery or spinal trauma\n* Low back pain associated with other pathologies (e.g., rheumatic diseases, multiple sclerosis, malignancy)\n* Instability conditions such as spondylolysis and spondylolisthesis\n* Pregnancy\n* Obesity (BMI ≥ 30 kg\u002Fm²)\n* Orthopedic problems or chronic diseases that may limit exercise participation\n* Physiotherapy or steroid injection treatment within the last 3 months",{"count":601,"type":23},52,[26],"Low back pain is one of the most prevalent musculoskeletal disorders worldwide and significantly reduces individuals' quality of life, functional capacity, and productivity. Lumbar-related leg pain (LRLP) is observed in a substantial proportion of patients with low back pain and is associated with neurodynamic dysfunctions arising from peripheral nerve sensitization. Although the effects of neural mobilization on pain and functional outcomes have been investigated in the literature, studies examining its short-term effects on balance and proprioception remain limited. Therefore, this study aims to determine the immediate effects of sciatic nerve neural mobilization on balance and proprioception in individuals with LRLP exhibiting peripheral nerve sensitivity.\n\nThe study will be designed as a prospective, randomized, controlled clinical trial. Participants will be recruited from individuals presenting to the Istinye University Health Practice and Research Center Hospital who meet the inclusion criteria. Following random allocation, 52 participants will be assigned either to the intervention group (neural mobilization) or the sham group (sham mobilization). In addition to a single-session standard conventional physiotherapy program, each group will receive its respective intervention protocol. Assessments will be conducted at two time points: before treatment and immediately after treatment.\n\nStatic and dynamic balance as well as proprioception will be evaluated using the ProKin balance system; muscle mechanical properties will be assessed using the MyotonPRO device; pain threshold will be measured with an algometer; and flexibility will be evaluated using the sit-and-reach test.",[219,605],"Leg Pain and\u002For Back Pain","2026-05-09",{"date":608,"type":39},"2026-05-15",{"date":610,"type":23},"2026-06-15",{"date":612,"type":23},"2026-10-15",{"name":45,"class":46},{"id":615,"slug":616,"hasResults":12,"nctId":617,"briefTitle":618,"officialTitle":618,"acronym":619,"eligibilityCriteria":620,"healthyVolunteers":17,"sex":312,"minAge":621,"maxAge":557,"enrollmentInfo":622,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":624,"conditions":625,"keywords":631,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":639,"lastUpdatePostDateStruct":640,"startDateStruct":642,"completionDateStruct":644,"leadSponsor":646,"locationsCount":47},"100637609","core-stability-postural-balance-and-flexibility-in-healthy-women-a-comparative-study-between-pilates-practitioners-and-sedentary-individuals-100637609","NCT07578714","Core Stability, Postural Balance, and Flexibility in Healthy Women: A Comparative Study Between Pilates Practitioners and Sedentary Individuals","CSBF-P","Inclusion Criteria:\n\n1. Healthy female volunteers aged 20-45.\n2. For the Pilates group: having practiced mat Pilates, reformer Pilates, or any equipment-based Pilates discipline for at least 6 months; attending regular 60-minute sessions at least twice a week with a certified instructor.\n3. For the control group: having a sedentary lifestyle (weekly moderate physical activity time less than 150 minutes).\n4. Objectively demonstrating sedentary status using the International Physical Activity Questionnaire (IPAQ); only participants in the \"low physical activity\" category will be included in the control group.\n5. Having full cognitive ability to understand, follow, and execute all physical assessment instructions.\n6. Willingness to voluntarily sign the informed consent form prior to the study.\n\nExclusion Criteria:\n\n1. History of any surgery involving the spine, pelvis, or lower extremities within the last 12 months prior to the study.\n2. Currently pregnant or less than 6 months postpartum.\n3. Diagnosed vestibular disorders or chronic clinical balance disorders.\n4. History of neurological disease (MS, Parkinson's, etc.) or systemic metabolic disorder (diabetes, etc.).\n5. Having a pain intensity greater than 2\u002F10 on the visual analog scale (VAS) in the lower back or lower extremities.\n6. Professional sports history or participation in other exercise programs exceeding 3 hours per week (excluding Pilates for the Pilates group).\n7. Acute musculoskeletal injuries or acute illnesses that may affect energy levels on the day of evaluation.\n8. Concurrent participation in other intensive core strengthening programs such as \"advanced yoga\" that may affect results.","20 Years",{"count":623,"type":23},55,"This study aims to compare core muscle stability, postural balance, and flexibility between healthy women who regularly practice Pilates and those with a sedentary lifestyle. The researcher will evaluate if long-term Pilates practice (5 months or more) leads to significant improvements in physical performance compared to a lack of regular exercise. Assessment tools include the Pressure Biofeedback Unit (PBU) for core activation, the McGill battery for endurance, the Y-Balance test for dynamic stability, and the Sit-and-Reach test for flexibility.",[626,627,628,629,630],"Core Stability","Postural Balance","Pilates, Core Stability","Pilates","Healthy Life Style",[629,632,633,634,635,636,637,638],"Flexibility","Trunk Muscle Endurance","Women's Health","Sedentary Behavior","Pressure Biofeedback Unit (PBU)","Y-Balance Test","McGill Battery","2026-05-05",{"date":641,"type":39},"2026-05-11",{"date":643,"type":23},"2026-05-13",{"date":645,"type":23},"2027-03-13",{"name":45,"class":46},""]