[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Jian-Jun Ou\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":89},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,68],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100614651","video-intervention-to-reduce-depression-related-stigma-among-adolescents-100614651",false,"NCT07282366","Video Intervention to Reduce Depression-related Stigma Among Adolescents","Effect of a Video-Based Intervention on Depression-Related Stigma Among Adolescents","Inclusion Criteria:\n\n* Adolescents aged 8-18 years.\n* Able to understand and complete questionnaires in Chinese.\n* Normal or corrected-to-normal vision and hearing.\n* Have at least a primary school education level.\n* Provide written informed consent from both the participant and their parent or guardian.\n* For the depressed group: score \\> 9 on the Patient Health Questionnaire for Adolescents (PHQ-A).\n* For the non-depressed group: score ≤ 9 on the PHQ-A.\n\nExclusion Criteria:\n\n* Presence of severe physical illness or neurological disease (e.g., traumatic brain injury).\n* Cognitive impairment, intellectual disability, or significant visual\u002Fhearing impairment that prevents participation.\n* Current psychotic symptoms or severe psychiatric comorbidities.\n* Active suicidal or self-harming behaviors during the study period.\n* Failure to comply with study procedures or withdrawal of consent.",true,"ALL","8 Years","18 Years",{"count":21,"type":22},500,"ESTIMATED","INTERVENTIONAL",[25],"NA","Depression-related stigma is a major barrier to help-seeking among adolescents with depression. In China, few interventions specifically target stigma reduction in this population. This study aims to evaluate the effectiveness of a video-based psychoeducational intervention in reducing depression-related stigma and improving help-seeking attitudes among adolescents.\n\nAdolescents aged 8-18 years are recruited from outpatient clinics and schools and screened using the Patient Health Questionnaire-9. Participants are categorized as depressed or non-depressed and randomly assigned into intervention or control groups: depressed adolescents receive a video on personal stigma, non-depressed adolescents receive a video on social stigma, while control groups watch a neutral myopia education video. The study hypothesizes that video-based education can effectively reduce stigma and promote positive help-seeking behaviors among adolescents.",[28],"Depression - Major Depressive Disorder","NOT_YET_RECRUITING","2025-12-01",{"date":32,"type":33},"2025-12-15","ACTUAL",{"date":35,"type":22},"2025-12-20",{"date":37,"type":22},"2026-12-20",{"name":39,"class":40},"Jian-Jun Ou","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":41},"100601414","blended-unified-protocol-for-chinese-adolescents-with-non-suicidal-self-injury-a-randomized-controlled-trial-100601414","NCT07110181","Blended Unified Protocol for Chinese Adolescents With Non-Suicidal Self-Injury: A Randomized Controlled Trial","A Randomized Controlled Trial Evaluating the Efficacy of a Blended Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Chinese Adolescents With Non-Suicidal Self-Injury","Inclusion Criteria:\n\n1. Aged between 12 and 17 years;\n2. Engaged in non-suicidal self-injury (NSSI) at least 5 times in the past 12 months, with at least 1 episode in the past month;\n3. Minimum education level of primary school or above;\n4. Participant and guardian fully understand the research content and agree to participate, with signed informed consent provided.\n\nExclusion Criteria:\n\n1. Suicide attempts in the past month or a score of ≥17 on the MINI National Neuropsychiatric Interview for Children (MINI KID 5.0), indicating a high risk of suicide;\n2. Diagnosis of a psychotic disorder, autism spectrum disorder, or other serious neurodevelopmental disorders according to the DSM-5;\n3. Presence of severe physical illness or other medical conditions that may affect the completion of treatment and evaluation;\n4. Currently receiving other professional psychotherapy or participating in another NSSI intervention study;\n5. Received 5 or more sessions of cognitive behavioral therapy (CBT) in the past 5 years;\n6. Having received electroconvulsive therapy (ECT) within the past 6 months.","12 Years","17 Years",{"count":52,"type":22},60,[25],"This study is an open-label, randomized controlled trial evaluating the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) in reducing non-suicidal self-injury (NSSI) among Chinese adolescents. This program is an annualized cognitive-behavioral therapy designed for adolescents aged 12-17 years who engage in non-suicidal self-injury behavior. Its primary goal is to reduce the intensity and frequency of distressing emotional experiences by teaching adolescents how to confront and respond to these emotions in more adaptive ways. In turn, this helps reduce self-injury impulses and behaviors. The UP-A is adapted to the Chinese cultural context and delivered as a blended treatment, combining face-to-face and online sessions.",[56],"Non-suicidal Self-injury (NSSI)",[58,59],"non-suicidal self-injury","adolescent","2025-07-31",{"date":62,"type":33},"2025-08-07",{"date":64,"type":22},"2025-08-15",{"date":66,"type":22},"2026-06-20",{"name":39,"class":40},{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":75,"targetDuration":4,"studyType":23,"phases":77,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":80,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":41},"100582071","blended-unified-protocol-in-chinese-adolescents-with-non-suicidal-self-injury-100582071","NCT06858540","Blended Unified Protocol in Chinese Adolescents With Non-Suicidal Self-Injury","A Blended Version of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Chinese Adolescents With Non-suicidal Self-injury: A Pilot Study","Inclusion Criteria:\n\n1. Aged between 12 and 17 years;\n2. Engaged in non-suicidal self-injury (NSSI) at least 5 times in the past 12 months, with at least 1 episode in the past month;\n3. Minimum education level of primary school or above;\n4. Participant and guardian fully understand the research content and agree to participate, with signed informed consent provided.\n\nExclusion Criteria:\n\n1. Suicide attempts in the past month or a score of ≥17 on the MINI National Neuropsychiatric Interview for Children (MINI KID 5.0), indicating a high risk of suicide;\n2. Diagnosis of a psychotic disorder, manic or hypomanic episode, autism spectrum disorder, or other serious neurodevelopmental disorders according to the DSM-5;\n3. Presence of severe physical illness or other medical conditions that may affect the completion of treatment and evaluation;\n4. Currently receiving other professional psychotherapy or participating in another NSSI intervention study;\n5. Received 5 or more sessions of cognitive behavioral therapy (CBT) in the past 5 years;\n6. Having received electroconvulsive therapy (ECT) within the past 6 months.",{"count":76,"type":22},12,[25],"This study utilizes the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) to address non-suicidal self-injury among Chinese adolescents. This program is an annualized cognitive-behavioral therapy designed for adolescents aged 12-17 years who engage in non-suicidal self-injury behavior. Its primary goal is to reduce the intensity and frequency of distressing emotional experiences by teaching adolescents how to confront and respond to these emotions in more adaptive ways. In turn, this helps reduce self-injury impulses and behaviors. The UP-A is adapted to the Chinese cultural context and delivered as a blended treatment, combining face-to-face and online sessions. The study will assess the feasibility, acceptability, and preliminary efficacy of this intervention through a single-arm design, which includes pretest, posttest, and follow-up assessments.",[56],"RECRUITING","2025-05-02",{"date":83,"type":33},"2025-05-04",{"date":85,"type":33},"2025-04-29",{"date":87,"type":22},"2025-10-30",{"name":39,"class":40},""]