[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Johnson & Johnson Vision Care, Inc.\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":60},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100655913","evaluation-of-approved-contact-lenses-cr-6657-100655913",false,"NCT07819305","Evaluation of Approved Contact Lenses (CR-6657)","Evaluation of Approved Contact Lenses","Potential subjects must satisfy all of the following criteria to be enrolled in the study:\n\n1. Read, understand, and sign the STATEMENT OF INFORMED CONSENT and receive a fully executed copy of the form.\n2. Appear able and willing to adhere to the instructions set forth in this clinical protocol\n3. Be between 18 and 39 (inclusive) years of age at the time of screening.\n4. By self-report, habitually wear reusable spherical (not toric or multifocal) silicone hydrogel contact lenses in both eyes in a daily wear modality (i.e., not extended wear). Habitual wear is defined as a self-reported minimum of 6 hours of wear per day and 5 days per week during the past 30 days.\n5. Have a habitual contact lens prescription that is current within the prior 12 months, and they must have worn that prescription for at least 2 weeks prior to entering the study.\n6. Possess a wearable pair of spectacles that provide correction for distance vision.\n\n   Inclusion criteria at baseline evaluation\n7. The vertex corrected subjective best sphere distance refraction must be between -1.00 D and -6.00 D (inclusive) in each eye.\n8. The magnitude of the cylindrical component of the subject's vertex corrected distance refraction must be less than or equal to 1.00 D (inclusive) in each eye with any degree of axis.\n9. The best corrected, monocular, distance visual acuity must be 20\u002F25 or better in each eye.\n\nPotential subjects who meet any of the following criteria will be excluded from participating in the study:\n\n1. Be currently pregnant or lactating.\n2. Be diabetic.\n3. Have any current ocular infection of any type.\n4. Be currently using any ocular medications. The use of topical ophthalmic allergy medications may be acceptable provided the medication regimen has remained stable for at least 14 days prior to enrollment and is expected to remain unchanged throughout study participation. All ophthalmic medications must be administered according to the approved product labeling, including any instructions regarding contact lens removal and reinsertion. Any changes in medication type, dose, frequency, duration, or administration instructions during the study will be documented and may result in a protocol deviation or study discontinuation.\n5. Routinely require or use artificial tears, lubricant eye drops, or contact lens rewetting drops for successful contact lens wear. Subjects with occasional, non-routine use may be enrolled provided they self-report discontinuation prior to enrollment and agree to refrain from their use during the study. Use of artificial tears, lubricant eye drops, or contact lens rewetting drops during a study lens wear period is not permitted. Any such use during the study will be documented and may result in a protocol deviation or study discontinuation.\n6. By self-report, have any ocular or systemic disease, allergies, infection, or use of medication that the investigator believes might contraindicate or interfere with contact lens wear, or otherwise compromise study endpoints, including infectious disease (e.g., hepatitis, tuberculosis), contagious immunosuppressive disease (e.g., Human Immunodeficiency Virus \\[HIV\\]), autoimmune disease (e.g. rheumatoid arthritis, Sjögren's syndrome), or history of serious mental illness or seizures. See Section 9.1 for additional details regarding excluded systemic medications.\n7. Have habitually worn rigid gas permeable (RGP) contact lenses, orthokeratology lenses, or hybrid lenses (e.g., SynergEyes, SoftPerm) within the past 6 months.\n8. Be currently wearing monovision, multifocal, or toric soft contact lenses.\n9. Be currently wearing lenses in an extended wear modality.\n10. Have a self-reported history of allergy, hypersensitivity, or intolerance to any study product or ancillary supply that, in the Investigator's judgment, could interfere with study participation or evaluation of study endpoints.\n11. Have participated in a contact lens or lens care product trial within 14 days prior to study enrollment.\n12. Be an employee (e.g., Investigator, Coordinator, Technician) or immediate family member of an employee (including partner, child, parent, grandparent, grandchild or sibling of the employee or their spouse) of the clinical site.\n13. Have clinically significant (grade 3 or higher on the FDA grading scale) slit lamp findings (e.g., corneal edema, neovascularization or staining, tarsal abnormalities or bulbar injection) or other corneal or ocular disease or abnormalities that the investigator believes might contraindicate contact lens wear or may otherwise compromise study endpoints (including entropion, ectropion, chalazia, recurrent styes, glaucoma, history of recurrent corneal erosions, aphakia, moderate or above corneal distortion, herpetic keratitis).\n14. Have strabismus (constant or intermittent) or amblyopia.\n15. Have fluctuations in vision due to clinically significant dry eye or other ocular conditions.\n16. Have had or have planned (within the study period) any ocular or intraocular surgery that may impact contact lens wear or study participation (e.g., radial keratotomy, PRK, LASIK, iridotomy, retinal laser photocoagulation, etc.).",true,"ALL","18 Years","39 Years",{"count":21,"type":22},150,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is a prospective, multi-site, bilateral, 2-week dispensing, randomized, controlled, single-masked (subjects), 2x2 crossover study to evaluate visual acuity.",[28],"Visual Acuity","RECRUITING","2026-09-24",{"date":32,"type":33},"2026-09-29","ACTUAL",{"date":35,"type":33},"2026-09-10",{"date":37,"type":22},"2026-12-03",{"name":39,"class":40},"Johnson & Johnson Vision Care, Inc.","INDUSTRY",8,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":16,"sex":17,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":54,"startDateStruct":55,"completionDateStruct":56,"leadSponsor":58,"locationsCount":59},"100653467","comparison-of-acuvue-oasys-max-1-day-multifocal-and-dailies-aquacomfort-plus-multifocal-100653467","NCT07788521","Comparison of ACUVUE® OASYS MAX 1-Day Multifocal and DAILIES® AquaComfort Plus® Multifocal","Potential subjects must satisfy all of the following criteria to be enrolled in the study:\n\n1. Read, understand, and sign the STATEMENT OF INFORMED CONSENT and receive a fully executed copy of the form.\n2. Appear able and willing to adhere to the instructions set forth in this clinical protocol.\n3. Be at least 40 years of age and not greater than 70 years of age at the time of consent.\n4. Own a wearable pair of spectacles if required for their distance vision.\n5. Be an adapted soft contact lens wearer in both eyes (i.e. worn lenses a minimum of 2 days per week for at least 6 hours per wear day, for 30 days or more duration).\n6. Either already be wearing a presbyopic contact lens correction (e.g., reading spectacles over contact lenses, multifocal or monovision contact lenses, etc.) or if not respond positively to at least one symptom on the \"Presbyopic Symptoms Questionnaire\".\n7. The subject's distance spherical equivalent refraction (vertex corrected if ≥-4.25 D) must be in the range of -1.50 D to -5.50 D in each eye.\n8. The subject's refractive cylinder must be ≤0.75 D in each eye.\n9. The subject's ADD power must be in the range of +0.75 D to +2.50 D.\n10. The subject must have distance best corrected visual acuity of 0.0 logMAR (20\u002F20 Snellen, 5.0 on the China standard 5-point logMAR visual acuity scale) or better in each eye.\n\nPotential subjects who meet any of the following criteria will be excluded from participating in the study:\n\n1. Be currently pregnant or lactating.\n2. Have any active or ongoing ocular or systemic allergies that may interfere with contact lens wear.\n3. Have been diagnosed with diabetes.\n4. Have any active or ongoing systemic disease, autoimmune disease, or use of medication, which may interfere with contact lens wear. This may include, but not be limited to, hyperthyroidism, Sjögren's syndrome, xerophthalmia, acne rosacea, Stevens-Johnson syndrome, and immunosuppressive diseases or any infectious diseases (e.g. hepatitis, tuberculosis).\n5. Have any previous, or planned, ocular or intraocular surgery (e.g. radial keratotomy, PRK, LASIK, lid procedures, dacryocystorhinostomy, peripheral iridotomy\u002Firidectomy, cataract surgery, retinal surgery, etc.).\n6. Have a history of amblyopia, strabismus or binocular vision abnormality.\n7. Use of any of the following medications within 1 week prior to enrollment: oral retinoid, oral tetracyclines, anticholinergics, oral phenothiazines, oral\u002Finhaled corticosteroids.\n8. Use of any ocular medication.\n9. Have a history of herpetic keratitis.\n10. Have a history of irregular cornea.\n11. Have a history of pathological dry eye.\n12. Have a history of glaucoma or glaucoma suspect.\n13. Have a history of any retinal disease\u002Fcondition that may interfere with any of the study assessments or are not stable and have potential to progress during the study.\n14. Have participated in any contact lens or lens care product clinical trial within 15 days prior to study enrollment.\n15. Be an employee (e.g., Investigator, Coordinator, Technician) or immediate family member of an employee (including partner, child, parent, grandparent, grandchild, sibling of the employee or their spouse) of the clinical site.\n16. Have any known hypersensitivity or allergic reaction to sodium fluorescein.\n17. Have Grade 3 or greater palpebral conjunctival observations or Grade 2 or greater slit lamp findings (e.g. corneal edema, corneal vascularization, corneal staining, bulbar injection, etc.) on the ISO 11980 classification scale, or any other corneal or ocular abnormalities which would contraindicate contact lens wear.\n18. Have any current ocular infection or inflammation.\n19. Have intraocular pressure in one or both eyes \\>21mmHg\n20. Have signs of any retinal disease\u002Fconditions that may interfere with any of the study assessments or are not stable and have potential to progress during the study.","40 Years","70 Years",{"count":21,"type":22},[25],"This study is a 4-visit, multi-site, prospective, controlled, randomized, single-masked (subjects), two-arm parallel group, bilateral, dispensing clinical trial to compare the performance of the Test lens to the Control lens in terms of safety and efficacy.",[28],{"date":32,"type":33},{"date":35,"type":33},{"date":57,"type":22},"2026-12-11",{"name":39,"class":40},11,""]