[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kira Bloomquist\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100653254","sarcoma-and-intra-infusion-exercise-for-better-outcomes-100653254",false,"NCT07785882","Sarcoma and Intra-infusion Exercise for Better Outcomes","Sarcoma and Intra-infusion Exercise for Better Outcomes: The SEB-trial","SEB","Inclusion Criteria:\n\n* Initiating at least two series of chemotherapy for non-resected sarcoma at Clinic 6, Herlev Hospital, Denmark\n* Eastern Cooperative Oncology Group performance status of 0-2\n* No mental or physical disabilities precluding exercise\n* Approval by the treating oncologist\n* Able to read Danish\n* Willing to sign informed consent\n\nExclusion Criteria:\n\n* Home-based chemotherapy\n* Infusions lasting under one hour\n* Elevated risk for developing cardiac issues (left ventricular ejection fraction ≤50%) based on routine echocardiography","ALL","18 Years",{"count":20,"type":21},16,"ESTIMATED","INTERVENTIONAL",[24],"NA","The main goal of this clinical trial is to determine: 1) the safety and 2) feasibility of moderate-intensity, intra-infusion aerobic exercise in people receiving chemotherapy for non-resected sarcoma and 3) assess whether intra-infusion exercise acutely increases tumor perfusion.\n\nThe trial aims to answer the following research questions:\n\n* Is intra-infusion aerobic exercise safe in people receiving chemotherapy for sarcoma?\n* Is intra-infusion aerobic exercise feasible in people receiving chemotherapy for sarcoma?\n* Does aerobic exercise induce acute increases in tumor perfusion?\n* In future work, which patient reported outcomes are relevant to explore in people receiving chemotherapy for sarcoma?\n\nAdverse event data and patient-reported quality-of-life outcomes will be compared to those of a historical control comprising patients who received chemotherapy for sarcoma within three years prior to study initiation.\n\nParticipants will:\n\n* Participate in light- to moderate-intensity aerobic exercise during chemotherapy infusion (intra-infusion exercise) for the duration of their treatment protocol.\n* Exercise will follow a 15-minute exercise \u002F 15-minute rest interval, totaling 30 minutes of exercise per hour of infusion.\n* Prior to initiating chemotherapy, undergo a single 15-minute exercise session. During peak exercise, a radioactive tracer will be injected intravenously followed by a single-photon emission computed tomography and computed tomography (SPECT \u002FCT) scan to obtain images of tumor perfusion. A resting SPECT\u002FCT scan will also be performed.",[27],"Sarcoma",[29,30,31,32,33],"exercise","chemotherapy","feasibility","adverse events","tumor perfusion","NOT_YET_RECRUITING","2026-08-21",{"date":37,"type":38},"2026-08-25","ACTUAL",{"date":40,"type":21},"2027-01-01",{"date":42,"type":21},"2028-10-31",{"name":44,"class":45},"Kira Bloomquist","OTHER",""]