[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Kutahya Health Sciences University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":630},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,38,0,25,[9,45,74,97,119,144,170,195,215,248,268,289,315,332,355,386,409,435,457,487,507,532,556,578,605],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100651919","effects-of-motivational-interviewing-on-pain-self-efficacy-and-exercise-behavior-in-individuals-with-knee-osteoarthritis-100651919",false,"NCT07767812","Effects of Motivational Interviewing on Pain Self-Efficacy and Exercise Behavior in Individuals With Knee Osteoarthritis","Investigation of the Effects of Motivational Interviewing on Pain Self-Efficacy and Exercise Behavior in Individuals With Knee Osteoarthritis","Inclusion Criteria:\n\n* Diagnosis of knee osteoarthritis according to American College of Rheumatology (ACR) criteria\n* Kellgren-Lawrence radiographic grade ≥2\n* Knee pain lasting longer than 3 months\n\nExclusion Criteria:\n\n* History of joint arthroplasty\n* Body mass index \\>40 kg\u002Fm²\n* Neuromuscular or neurological diseases such as stroke, Parkinson's disease, or multiple sclerosis\n* History of lower-extremity joint fracture\n* Hip osteoarthritis","ALL","40 Years",{"count":20,"type":21},56,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled trial aims to investigate the effects of motivational interviewing added to a neuromuscular exercise and home exercise program on pain self-efficacy, exercise behavior, pain intensity, physical performance, and functional status in individuals with knee osteoarthritis. Sixty individuals diagnosed with knee osteoarthritis will be randomly allocated to either an intervention group or a control group. The intervention group will receive motivational interviewing in addition to neuromuscular exercise and a home exercise program, whereas the control group will receive neuromuscular exercise and the same home exercise program. Outcomes will be assessed at baseline, immediately after the intervention, and six weeks after the intervention.",[27],"Knee Arthritis Osteoarthritis",[29,30,31],"KNEE OSTEOARTHRITIS","MOTIVATIONAL INTERVIEWING","EXERCISE","RECRUITING","2026-08-14",{"date":35,"type":36},"2026-08-17","ACTUAL",{"date":38,"type":36},"2026-02-01",{"date":40,"type":21},"2026-12-31",{"name":42,"class":43},"Kutahya Health Sciences University","OTHER",1,{"id":46,"slug":47,"hasResults":12,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":55,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":44},"100651861","pain-phenotypes-in-individuals-with-multiple-sclerosis-100651861","NCT07766213","Pain Phenotypes in Individuals With Multiple Sclerosis","Pain Phenotyping in Multiple Sclerosis Based on IASP Criteria","Inclusion Criteria:\n\n* Age 18 years or older\n* Definite diagnosis of multiple sclerosis according to the McDonald criteria\n* No MS relapse or high-dose steroid treatment within the previous 3 months\n* Pain intensity ≥2 on the Numeric Rating Scale in at least one body region for at least 3 months\n* Ability to read, understand, and communicate in Turkish\n\nExclusion Criteria:\n\n* Pregnancy\n* Severe psychiatric disorder and\u002For severe cognitive impairment confirmed by a neurologist or neuropsychiatrist\n* Presence of a serious pathology or disease that may compromise the assessment process or affect clinical decision-making, including metastasis, cancer, untreated or unhealed fractures, neurological disorders other than multiple sclerosis, or a history of diabetes","18 Years",{"count":54,"type":21},60,"1 Day","OBSERVATIONAL","This observational cross-sectional study aims to determine chronic pain phenotypes in individuals with multiple sclerosis (MS) and to investigate the clinical characteristics associated with different pain phenotypes. Participants with MS and chronic pain will undergo a comprehensive clinical assessment to identify nociceptive, neuropathic, nociplastic, and mixed pain phenotypes. The assessment will include clinical history, pain characteristics and distribution, quantitative sensory testing, pain intensity, disease severity, fatigue, health-related quality of life, and pain catastrophizing. The clinical characteristics of participants with different pain phenotypes will subsequently be compared.",[59,60],"Multiple Sclerosis","Chronic Pain",[62,63,64,65],"CHRONIC PAIN","NEUROPATHIC PAIN","NOCIPLASTIC PAIN","MULTIPLE SCLEROSIS","NOT_YET_RECRUITING",{"date":68,"type":36},"2026-08-18",{"date":70,"type":21},"2026-08-15",{"date":72,"type":21},"2027-09-15",{"name":42,"class":43},{"id":75,"slug":76,"hasResults":12,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":81,"enrollmentInfo":82,"targetDuration":55,"studyType":56,"phases":4,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":92,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":96,"locationsCount":44},"100651759","pain-phenotypes-in-individuals-with-chronic-low-back-pain-100651759","NCT07766200","Pain Phenotypes in Individuals With Chronic Low Back Pain","Pain Phenotypes in Chronic Low Back Pain Based on IASP Criteria","Inclusion Criteria:\n\n* Low back pain persisting for at least 3 months or present for at least 3 months during the previous 6 months, defined as pain located between the posterior lower costal margins and the inferior gluteal folds\n* Pain intensity ≥2 on the Numeric Rating Scale\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Inability to read and write Turkish\n* History of lumbar surgery\n* Presence of a systemic condition affecting sensory function\n* History of spinal surgery within the previous 6 months or suspected spinal fracture\n* Inability to complete the study assessments","70 Years",{"count":83,"type":21},80,"This observational cross-sectional study aims to determine pain phenotypes in individuals with chronic low back pain (CLBP). Participants will be classified according to a mechanism-based clinical pain phenotyping algorithm as having nociceptive, neuropathic, nociplastic, or mixed pain. Clinical history, quantitative sensory assessment, pain characteristics and distribution, central sensitization-related symptoms, disability, health-related quality of life, and pain catastrophizing will be assessed. In addition, the intra-rater and inter-rater reliability of the pain phenotyping algorithm will be investigated, and the clinical characteristics of different pain phenotypes will be compared.",[86],"Chronic Low-back Pain (cLBP)",[88,89,90,91],"pain phenotype","pain science","chronic pain","nociplastic pain",{"date":68,"type":36},{"date":94,"type":36},"2025-01-02",{"date":40,"type":21},{"name":42,"class":43},{"id":98,"slug":99,"hasResults":12,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":104,"enrollmentInfo":105,"targetDuration":4,"studyType":22,"phases":107,"briefSummary":108,"conditions":109,"keywords":111,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":118,"locationsCount":44},"100652079","effects-of-the-timing-of-vagus-nerve-stimulation-combined-with-exercise-in-chronic-neck-pain-100652079","NCT07769034","Effects of the Timing of Vagus Nerve Stimulation Combined With Exercise in Chronic Neck Pain","Does Timing Matter? Effects of Transcutaneous Auricular Vagus Nerve Stimulation Before and After Exercise in Chronic Neck Pain: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of chronic neck pain confirmed by a physical medicine and rehabilitation physician.\n* Age between 18 and 65 years.\n* Neck pain persisting or recurring for at least 3 months.\n* Ability to participate in the exercise program included in the study protocol.\n* No contraindication to transcutaneous auricular vagus nerve stimulation.\n* Willingness to provide written informed consent.\n* Willingness to participate regularly in the planned exercise and assessment sessions.\n\nExclusion Criteria:\n\n* Cervical radiculopathy or specific neurological findings.\n* Previous cervical spine surgery.\n* Serious cardiovascular disease.\n* Serious neurological or systemic disease.\n* Pregnancy.\n* Orthopedic or musculoskeletal conditions preventing participation in exercise.\n* Cognitive or communication problems that prevent completion of the assessment instruments.\n* Inability or unwillingness to comply with the study protocol or attend scheduled sessions.","65 Years",{"count":106,"type":21},81,[24],"This randomized controlled trial aims to investigate whether the timing of transcutaneous auricular vagus nerve stimulation (taVNS) relative to exercise influences clinical and autonomic outcomes in individuals with chronic neck pain.\n\nParticipants will be randomly allocated to one of three groups: taVNS applied before exercise, taVNS applied after exercise, or exercise alone. All groups will receive a standardized exercise program designed for chronic neck pain. The intervention will be conducted over a 6- to 8-week period.\n\nThe effects of the interventions will be evaluated using pain intensity, neck-related disability, sleep quality, heart rate variability, and exercise adherence. The study will determine whether applying taVNS before or after exercise provides additional benefits compared with exercise alone and whether the timing of stimulation influences treatment outcomes.",[110],"Chronic Neck Pain",[62,112,31],"VAGAL NERVE STIMULATION","2026-08-12",{"date":35,"type":36},{"date":116,"type":21},"2026-09-14",{"date":72,"type":21},{"name":42,"class":43},{"id":120,"slug":121,"hasResults":12,"nctId":122,"briefTitle":123,"officialTitle":124,"acronym":4,"eligibilityCriteria":125,"healthyVolunteers":126,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":127,"targetDuration":4,"studyType":22,"phases":129,"briefSummary":130,"conditions":131,"keywords":133,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":143,"locationsCount":44},"100650496","nurse-led-motivational-interviewing-for-blood-pressure-control-100650496","NCT07747025","Nurse-Led Motivational Interviewing for Blood Pressure Control","The Effect of Nurse-Led Individual and Family-Involved Motivational Interviewing on Blood Pressure Control in Patients With Hypertension: A Three-Arm Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18 years or older\n* Diagnosed with hypertension for at least 6 months\n* Using antihypertensive medication\n* Able to read and understand Turkish\n* Conscious and able to communicate\n* Providing written informed consent\n* Having at least one family member who can support hypertension management and participate in sessions when needed\n\nExclusion Criteria:\n\n* Advanced cognitive impairment\n* Active psychiatric crisis\n* History of a serious cardiovascular event within the last 3 months\n* Terminal illness\n* Serious physical condition that may prevent regular participation in intervention sessions\n* Concurrent participation in another structured education program",true,{"count":128,"type":21},180,[24],"Hypertension is one of the most important risk factors for cardiovascular morbidity and mortality. Effective hypertension management requires medication adherence, lifestyle modification, regular blood pressure monitoring, and self-management behaviors. Motivational interviewing is a counseling approach that may support behavior change and improve hypertension management.\n\nThis study aims to evaluate the effects of nurse-led individual motivational interviewing and family-involved motivational interviewing on blood pressure control in patients with hypertension. The study will be conducted as a single-center, three-arm, parallel-group, randomized controlled trial. A total of 180 patients with hypertension will be randomly assigned to one of three groups: usual care, individual motivational interviewing, or family-involved motivational interviewing.\n\nParticipants in the intervention groups will receive a 6-week nurse-led motivational interviewing program. In the family-involved motivational interviewing group, a family member who supports hypertension management will also participate in the sessions. Data will be collected at baseline, 6 weeks, and 18 weeks. The primary outcome is systolic blood pressure. Secondary outcomes include diastolic blood pressure, hypertension knowledge level, treatment adherence, and hypertension self-efficacy.",[132],"Hypertension",[132,134,135,136,137],"Blood pressure control","Motivational interviewing","Family involvement","Nursing intervention","2026-08-11",{"date":113,"type":36},{"date":141,"type":36},"2026-08-01",{"date":40,"type":21},{"name":42,"class":43},{"id":145,"slug":146,"hasResults":12,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":4,"eligibilityCriteria":150,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":151,"targetDuration":4,"studyType":22,"phases":153,"briefSummary":154,"conditions":155,"keywords":158,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":167,"leadSponsor":169,"locationsCount":44},"100650367","nurse-led-dialysis-self-management-program-for-hemodialysis-distress-100650367","NCT07747012","Nurse-Led Dialysis Self-Management Program for Hemodialysis Distress","The Effect of a Nurse-Led Needs-Based Dialysis Self-Management Program on Dialysis-Related Distress in Hemodialysis Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18 years or older\n* Receiving hemodialysis treatment for at least 3 months\n* Receiving hemodialysis treatment at least twice per week\n* Able to read and understand Turkish\n* Conscious and able to communicate\n* Providing written informed consent\n\nExclusion Criteria:\n\n* Advanced cognitive impairment\n* Active psychiatric crisis\n* History of major surgery or acute severe illness within the last 3 months\n* Planned kidney transplantation in the near future\n* Serious physical or communication problems that may prevent regular participation in the intervention sessions\n* Concurrent participation in another structured education or psychosocial intervention program",{"count":152,"type":21},100,[24],"Hemodialysis patients may experience dialysis-related distress due to long-term treatment requirements, dietary and fluid restrictions, medication use, vascular access problems, dialysis-related symptoms, and psychosocial challenges. Nurse-led self-management programs may help patients improve dialysis self-management, reduce distress, and support treatment adherence.\n\nThis study aims to evaluate the effect of a nurse-led needs-based dialysis self-management program on dialysis-related distress in patients receiving hemodialysis. The study will be conducted as a single-center, two-arm, parallel-group, randomized controlled trial. A total of 100 adult hemodialysis patients will be randomly assigned to either the intervention group or the control group in a 1:1 ratio.\n\nParticipants in the intervention group will receive a 6-week nurse-led needs-based dialysis self-management program in addition to routine hemodialysis care. Participants in the control group will continue routine hemodialysis care. Data will be collected at baseline, 6 weeks, and 18 weeks. The primary outcome is dialysis-related distress. Secondary outcomes include illness and treatment uncertainty, treatment adherence, and clinical adherence indicators.",[156,157],"Hemodialysis","Dialysis-Related Distress",[156,159,160,137,161,162,163],"Dialysis-related distress","Self-management","Patient education","Treatment adherence","Illness uncertainty",{"date":165,"type":36},"2026-08-13",{"date":141,"type":36},{"date":168,"type":21},"2026-12-15",{"name":42,"class":43},{"id":171,"slug":172,"hasResults":12,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":177,"enrollmentInfo":178,"targetDuration":55,"studyType":56,"phases":4,"briefSummary":180,"conditions":181,"keywords":183,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":189,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":44},"100635924","effects-of-hemiplegic-shoulder-pain-on-upper-extremity-motor-function-trunk-control-fear-of-falling-mobility-and-indepence-in-activities-of-daily-living-in-patients-with-stroke-100635924","NCT07559006","Effects of Hemiplegic Shoulder Pain on Upper Extremity Motor Function, Trunk Control, Fear of Falling, Mobility and Indepence in Activities of Daily Living in Patients With Stroke","Effects of Hemiplegic Shoulder Pain on Body Structure and Activity in Patients With Stroke","Inclusion Criteria:\n\n* Having a diagnosis of stroke\n* Aged ≥ 18 years old\n* Mini Mental State Test score ≥ 24 points\n* Having a shoulder VAS score of 3 points or higher\n\nExclusion Criteria:\n\n* Having another neurological disease (except for stroke\n* Having communication deficits or neglect\n* Having a surgery upper or lower extremity in the last 6 months","80 Years",{"count":179,"type":21},62,"This study aimed to examine the effects of hemiplegic shoulder pain on upper extremity motor assessment, trunk control, fear of falling, mobility, and functional indepedence patients with stroke.",[182],"Stroke",[184,185,186,187,188],"stroke","hemiplegic shoulder pain","trunk control","upper extremity","mobility",{"date":165,"type":36},{"date":191,"type":36},"2026-03-20",{"date":193,"type":21},"2026-11-15",{"name":42,"class":43},{"id":196,"slug":197,"hasResults":12,"nctId":198,"briefTitle":199,"officialTitle":199,"acronym":4,"eligibilityCriteria":200,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":104,"enrollmentInfo":201,"targetDuration":4,"studyType":22,"phases":203,"briefSummary":204,"conditions":205,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":214,"locationsCount":4},"100651114","the-effect-of-carpal-tunnel-syndrome-phenotyping-on-response-to-treatment-100651114","NCT07754708","The Effect of Carpal Tunnel Syndrome Phenotyping on Response to Treatment","Inclusion Criteria:\n\n* Being diagnosed with CTS\n* Being suitable for the neuropathic pain phenotype\n* Being between the ages of 18-65\n* Volunteering to participate in the study\n\nExclusion Criteria:\n\n* Having systemic inflammatory disease\n* Having a disease that may cause polyneuropathy such as diabetes mellitus\n* Having a pacemaker\n* Having a disease affecting the central nervous system\n* Having cervical radiculopathy\n* History of previous operation or local steroid injection due to CTS\n* Hypersensitivity to heat and cold",{"count":202,"type":21},50,[24],"The aim of this study was to evaluate the effect of Carpal Tunnel Syndrome (CTS) phenotyping on responsiveness to clinical interventions in individuals with CTS.",[206],"Carpal Tunnel Syndrome","2026-08-04",{"date":209,"type":36},"2026-08-10",{"date":211,"type":21},"2026-10-27",{"date":213,"type":21},"2027-12-27",{"name":42,"class":43},{"id":216,"slug":217,"hasResults":12,"nctId":218,"briefTitle":219,"officialTitle":220,"acronym":221,"eligibilityCriteria":222,"healthyVolunteers":12,"sex":17,"minAge":223,"maxAge":224,"enrollmentInfo":225,"targetDuration":4,"studyType":22,"phases":227,"briefSummary":228,"conditions":229,"keywords":233,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":241,"startDateStruct":243,"completionDateStruct":245,"leadSponsor":247,"locationsCount":44},"100622832","espb-vs-spsip-for-postoperative-analgesia-after-cabg-100622832","NCT07388745","ESPB vs SPSIP for Postoperative Analgesia After CABG","A Randomized Trial Comparing Erector Spinae Plane Block Versus Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesic Efficacy in Patients Undergoing Coronary Artery Bypass Graft Surgery","ESP-SPSIP-CABG","Inclusion Criteria:\n\n* Age 45-85 years\n* Scheduled for elective coronary artery bypass graft (CABG) surgery\n* American Society of Anesthesiologists (ASA) I-II-III\n* Patients who provide written informed consent and agree to participate in the study\n\nExclusion Criteria:\n\n* Emergency cases\n* ASA IV-V\n* Known allergy to local anesthetics\n* Coagulopathy (platelet count \\\u003C100,000\u002Fmm³, INR \\>1.5, aPTT \\>1.5× normal)\n* Infection at the block injection site\n* Pregnancy\n* Patients who do not provide written informed consent or decline to participate after being informed","45 Years","85 Years",{"count":226,"type":21},64,[24],"This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral Serratus Posterior Superior Intercostal Plane Block (SPSIPB) in adult patients (45-85 years, ASA I-III) undergoing elective coronary artery bypass graft surgery. The primary outcome is postoperative pain intensity assessed by Numeric Rating Scale (NRS) at 2, 4, 8, 16, 24, and 48 hours after surgery. Secondary outcomes include intraoperative fentanyl\u002Fremifentanil consumption, postoperative morphine consumption, patient-controlled analgesia (PCA) demand\u002Fdelivery parameters (if PCA is used), need for rescue analgesics, extubation and mobilization times, peak inspiratory flow measured by incentive spirometry at predefined time points, ICU and hospital length of stay, recovery quality (QoR-15 at 0, 24, and 48 hours), mortality, and block-related adverse events.",[230,231,232],"Coronary Arterial Disease","Coronary Artery Bypass Grafting (CABG) Surgery","Postoperative Pain Management",[234,235,236,237,238,239,240],"Coronary Artery Bypass Grafting","Erector Spinae Plane Block","Serratus Posterior Superior Intercostal Plane Block","Regional Anesthesia","Ultrasound-Guided Nerve Block","Postoperative Pain","Numeric Rating Scale",{"date":242,"type":36},"2026-08-05",{"date":244,"type":36},"2026-03-01",{"date":246,"type":21},"2026-09-30",{"name":42,"class":43},{"id":249,"slug":250,"hasResults":12,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":126,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":255,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":257,"conditions":258,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":267,"locationsCount":44},"100623914","mobbing-exposure-and-job-satisfaction-among-physiotherapists-100623914","NCT07402824","Mobbing Exposure and Job Satisfaction Among Physiotherapists","Investigation of Mobbing Exposure and Job Satisfaction Levels Among Physiotherapists","Inclusion Criteria:\n\n* Currently working or having previously worked as a physiotherapist in Turkey.\n* Graduation from a minimum 4-year Physiotherapy and Rehabilitation degree program.\n* Voluntary participation.\n\nExclusion Criteria:\n\n* Forms with incorrect answers to dummy questions (trap questions).\n* Forms with missing data.",{"count":256,"type":21},200,"Physiotherapists, who hold a significant place in the healthcare sector, are at risk for mobbing and low levels of job satisfaction due to both demanding physical working conditions and emotional stress. This study was designed to investigate the mobbing exposure and job satisfaction levels of physiotherapists.",[259,260],"Job Satisfaction","Bullying, Workplace","2026-07-29",{"date":263,"type":36},"2026-07-30",{"date":265,"type":36},"2026-02-04",{"date":40,"type":21},{"name":42,"class":43},{"id":269,"slug":270,"hasResults":12,"nctId":271,"briefTitle":272,"officialTitle":272,"acronym":4,"eligibilityCriteria":273,"healthyVolunteers":12,"sex":274,"minAge":18,"maxAge":81,"enrollmentInfo":275,"targetDuration":4,"studyType":22,"phases":276,"briefSummary":277,"conditions":278,"keywords":4,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":44},"100649747","efficacy-of-transcutaneous-electrical-stimulation-therapy-in-the-treatment-of-overactive-bladder-developing-after-stroke-100649747","NCT07740668","Efficacy of Transcutaneous Electrical Stimulation Therapy in the Treatment of Overactive Bladder Developing After Stroke","Inclusion Criteria:\n\n* Female\n* Age 40 to 70 years\n* History of ischemic or hemorrhagic stroke at least 6 months before enrollment\n* Presence of overactive bladder symptoms\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Age outside the study range\n* Pregnancy or breastfeeding\n* Active urinary tract infection\n* Neurogenic conditions other than stroke affecting bladder function\n* Inability to comply with study procedures\n* Refusal or inability to provide informed consent","FEMALE",{"count":202,"type":21},[24],"This study is a prospective, randomized controlled clinical trial designed to evaluate the efficacy of transcutaneous electrical stimulation (posterior tibial nerve stimulation, PTNS) in the treatment of overactive bladder (OAB) developing after stroke.\n\nPrimary Hypothesis: PTNS therapy will significantly improve OAB symptoms in post-stroke patients compared to standard care\u002Fsham stimulation.\n\nPrimary Outcome Measure: Change from baseline in Overactive Bladder Symptom Score (OABSS) and\u002For frequency of urgency episodes as assessed after 12 weeks of treatment.\"",[182,279,280],"Overactive Bladder (OAB)","Tibial Nerve","2026-07-28",{"date":283,"type":36},"2026-07-31",{"date":285,"type":21},"2026-09-01",{"date":287,"type":21},"2027-10-01",{"name":42,"class":43},{"id":290,"slug":291,"hasResults":12,"nctId":292,"briefTitle":293,"officialTitle":294,"acronym":4,"eligibilityCriteria":295,"healthyVolunteers":12,"sex":17,"minAge":296,"maxAge":81,"enrollmentInfo":297,"targetDuration":4,"studyType":22,"phases":298,"briefSummary":299,"conditions":300,"keywords":303,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":308,"lastUpdatePostDateStruct":309,"startDateStruct":310,"completionDateStruct":312,"leadSponsor":314,"locationsCount":44},"100631761","effects-of-aerobic-exercise-in-rheumatoid-arthritis-100631761","NCT07504887","Effects of Aerobic Exercise in Rheumatoid Arthritis","Evaluation of the Effects of Aerobic Exercise Therapy on Quality of Life, Functional Capacity, Mood, Fatigue, and Inflammatory Markers in Patients With Rheumatoid Arthritis","Inclusion Criteria:\n\n* Diagnosed with RA according to ACR\u002FEULAR 2010 criteria\n* Female patients aged 30-70 years\n* Low disease activity (DAS-28 \\\u003C 3.2)\n* Voluntary participation\n\nExclusion Criteria:\n\n* Cardiovascular diseases (CAD, heart failure, etc.)\n* Respiratory diseases\n* Neurological disorders\n* BMI \\> 35\n* Malignancy\n* Pregnancy or breastfeeding\n* Recent medication change (last 3 months)\n* Musculoskeletal conditions preventing exercise","30 Years",{"count":226,"type":21},[24],"This study aims to evaluate the effects of aerobic exercise therapy on quality of life, functional capacity, mood, and fatigue in patients with rheumatoid arthritis. Additionally, the study investigates the impact of aerobic exercise on inflammatory markers, pain, and disease activity.",[301,302],"Rheumatic Diseases","Rheumatic Disorder",[304,305,306,307],"RHEUMATIC DISEASE","RHEUMATIC ARTRIT","PAIN","PHYSICAL MEDICINE AND REHABILITATION","2026-07-26",{"date":281,"type":36},{"date":311,"type":36},"2026-04-01",{"date":313,"type":21},"2027-01-30",{"name":42,"class":43},{"id":316,"slug":317,"hasResults":12,"nctId":318,"briefTitle":319,"officialTitle":320,"acronym":4,"eligibilityCriteria":321,"healthyVolunteers":12,"sex":17,"minAge":296,"maxAge":322,"enrollmentInfo":323,"targetDuration":4,"studyType":22,"phases":324,"briefSummary":325,"conditions":326,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":308,"lastUpdatePostDateStruct":328,"startDateStruct":329,"completionDateStruct":330,"leadSponsor":331,"locationsCount":44},"100631494","high-intensity-laser-therapy-in-hemiplegic-shoulder-pain-100631494","NCT07501416","High-Intensity Laser Therapy in Hemiplegic Shoulder Pain","Effectiveness of High-Intensity Laser Therapy Combined With Exercise on Clinical and Ultrasonographic Outcomes in Patients With Hemiplegic Shoulder Pain","Inclusion Criteria:\n\n* Age 30-75 years\n* Hemiplegic shoulder pain after stroke\n* Stroke within last 6 months\n* VAS ≥ 3 for pain\n* Medically stable\n\nExclusion Criteria:\n\n* Neurological disorders (MS, Parkinson, etc.)\n* Recent shoulder surgery\u002Finjection\n* Botulinum toxin (last 6 months)\n* Malignancy\n* Pregnancy\n* Epilepsy or photosensitivity\n* Cognitive impairment","75 Years",{"count":54,"type":21},[24],"This randomized, sham-controlled clinical trial aims to evaluate the effectiveness of high-intensity laser therapy (HILT) combined with exercise on pain, functional status, disability, and ultrasonographic findings in patients with hemiplegic shoulder pain following stroke.",[327],"Hemiplegia and\u002For Hemiparesis Following Stroke",{"date":281,"type":36},{"date":311,"type":36},{"date":313,"type":21},{"name":42,"class":43},{"id":333,"slug":334,"hasResults":12,"nctId":335,"briefTitle":336,"officialTitle":337,"acronym":4,"eligibilityCriteria":338,"healthyVolunteers":12,"sex":17,"minAge":339,"maxAge":340,"enrollmentInfo":341,"targetDuration":4,"studyType":22,"phases":342,"briefSummary":343,"conditions":344,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":348,"lastUpdatePostDateStruct":349,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":354,"locationsCount":44},"100618718","effects-of-swaddling-and-nesting-on-pain-and-stress-in-newborns-100618718","NCT07335263","Effects of Swaddling and Nesting on Pain and Stress in Newborns","The Effect of Swaddling and Nesting Methods on Pain and Stress Levels in Newborns Undergoing Noninvasive Mechanical Ventilation","Inclusion Criteria:\n\n* Birth week greater than 35 weeks and birth weight greater than 2000 grams\n* Requirement for nasal CPAP\u002Fnoninvasive mechanical ventilation\n* Legal guardians' consent to participate in the study\n* Postnatal diagnosis of transient tachypnea of the newborn\n\nExclusion Criteria:\n\nMother:\n\n* Taking cortisol-containing medication during the antenatal period\n* Taking narcotics during the antenatal period\n* Having chorioamnionitis\n* Having a metabolic disorder (adrenal insufficiency, etc.)\n\nNewborn:\n\n* Amniotic fluid stained with meconium\n* Being intubated\n* Having an Apgar score below 6\n* Receiving analgesic or narcotic drugs for sedation\n* The newborn receiving cortisol-containing medication\n* Being unable to obtain a saliva sample or the sample being contaminated with blood\n* Signs of nasal injury during noninvasive mechanical ventilation\n* Congenital defects (spina bifida, gastroschisis, etc.) that prevent positioning using the swaddling or cradling methods\n* Resuscitation\n* Cerebral hypoxia-ischemia\n* Non-respiratory causes (congenital pneumonia, respiratory distress syndrome, congenital heart disease, hypocalcemia, persistent hypoglycemia, development of sepsis)\n* Hypocalcemia (low calcium level detected in blood gas sample taken while establishing an intravenous line prior to nCPAP)","0 Days","28 Days",{"count":152,"type":21},[24],"This study aims to investigate the effects of swaddling and cradling methods on pain and stress levels in newborn infants receiving respiratory support.\n\nInfants receiving respiratory support in the neonatal intensive care unit may experience stress and discomfort during treatment. In this study, two different care methods that help infants feel more comfortable and secure will be scientifically compared. Only one of the Swaddling or Nesting methods will be applied to the newborns participating in the study. These methods are comfort-enhancing care practices routinely used in neonatal intensive care that do not harm the baby. The newborn's heart rate, respiratory rate, oxygen level, pain and stress symptoms will be closely and safely monitored by the healthcare team. A pain-free saliva sample will be collected to assess the newborn's stress level. It does not involve needles, does not hurt, and takes approximately 2 minutes. Pain and stress levels will be assessed in a multifaceted manner using clinical observation, physiological parameters, and saliva cortisol levels. The study aims to contribute to the strengthening of evidence-based non-pharmacological care practices in neonatal intensive care.",[345,346,347],"Stress","Non Pharmacological Intervention","Newborn Diseases","2026-07-25",{"date":281,"type":36},{"date":351,"type":36},"2025-02-17",{"date":353,"type":21},"2026-12-13",{"name":42,"class":43},{"id":356,"slug":357,"hasResults":12,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":361,"eligibilityCriteria":362,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":363,"targetDuration":4,"studyType":22,"phases":365,"briefSummary":366,"conditions":367,"keywords":371,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":379,"lastUpdatePostDateStruct":380,"startDateStruct":382,"completionDateStruct":384,"leadSponsor":385,"locationsCount":44},"100643619","nurse-led-caregiver-support-program-in-home-palliative-care-100643619","NCT07593729","Nurse-Led Caregiver Support Program in Home Palliative Care","Effect of a Nurse-Led Caregiver Support Program on Caregiver Competency and Healthcare Utilization Among Family Caregivers in Home Palliative Care: A Randomized Controlled Trial","CARE-PAL","Inclusion Criteria:\n\n* Adult family caregivers of patients receiving home palliative care services\n* Age 18 years or older\n* Being the primary caregiver responsible for the patient's daily care\n* Ability to communicate in Turkish\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Professional or paid caregivers\n* Caregivers with severe cognitive impairment or severe psychiatric disorders\n* Inability to participate in follow-up assessments",{"count":364,"type":21},150,[24],"This randomized controlled trial aims to evaluate the effect of a nurse-led caregiver support program on caregiver competency and healthcare utilization among family caregivers of patients receiving home palliative care. Family caregivers in the intervention group will receive a structured 6-week nurse-led support program including face-to-face education, weekly telephone coaching, caregiver guidance materials, and decision support for symptom management and healthcare utilization. The control group will continue to receive routine home palliative care services. Primary outcome is caregiver competency. Secondary outcomes include caregiver burden, self-efficacy, patient symptom burden, emergency department visits, and hospitalizations.",[368,369,370],"Palliative Care","Caregiver Burden","Home Care",[372,373,374,375,376,377,378],"Nurse-led intervention","Family caregiver","Caregiver competency","Home care","Randomized controlled trial","Palliative care","Healthcare utilization","2026-07-24",{"date":381,"type":36},"2026-07-27",{"date":383,"type":36},"2026-05-12",{"date":246,"type":21},{"name":42,"class":43},{"id":387,"slug":388,"hasResults":12,"nctId":389,"briefTitle":390,"officialTitle":391,"acronym":4,"eligibilityCriteria":392,"healthyVolunteers":12,"sex":17,"minAge":104,"maxAge":4,"enrollmentInfo":393,"targetDuration":4,"studyType":22,"phases":394,"briefSummary":395,"conditions":396,"keywords":398,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":379,"lastUpdatePostDateStruct":403,"startDateStruct":404,"completionDateStruct":406,"leadSponsor":408,"locationsCount":44},"100642824","nurse-led-telehealth-frailty-management-in-older-adults-100642824","NCT07634406","Nurse-Led Telehealth Frailty Management in Older Adults","The Effect of a Nurse-Led Telehealth-Supported Multicomponent Frailty Management Program on Frailty and Functional Status in Older Adults Living at Home: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 65 years or older\n* Living at home and not receiving institutional care\n* Frail or at risk of frailty\n* Having sufficient hearing and cognitive ability to communicate by telephone\n* Able to read, understand, and communicate in Turkish\n* Providing written informed consent\n\nExclusion Criteria:\n\n* Having advanced cognitive impairment such as dementia\n* Having hearing or speech problems that prevent communication\n* Being bedridden\n* Being in the terminal stage of illness\n* Participating in another intervention or education program at the same time\n* Having a serious physical or psychiatric condition that may prevent regular participation in the intervention",{"count":152,"type":21},[24],"Frailty is an important geriatric syndrome associated with reduced physiological reserve, functional decline, falls, hospitalization, and increased health care use among older adults. This randomized controlled trial aims to evaluate the effect of a nurse-led telehealth-supported multicomponent frailty management program on frailty level and functional status in older adults living at home.\n\nThe study will be conducted as a single-center, two-arm, parallel-group randomized controlled trial. A total of 100 older adults aged 65 years and older who are living at home and are frail or at risk of frailty will be randomly assigned to either the intervention group or the control group in a 1:1 ratio.\n\nParticipants in the intervention group will receive an 6-week nurse-led telehealth-supported frailty management program, including weekly telephone counseling and individualized follow-up. Participants in the control group will continue usual care. Data will be collected at baseline, at 6 weeks, and at 18 weeks. The primary outcome is frailty level measured using the FRAIL Scale. Secondary outcomes include functional status, depressive symptoms, number of falls, emergency department visits, and hospitalizations.",[397],"Frailty",[399,400,137,401,402,375],"Older adults","Telehealth","Frailty management","Functional status",{"date":381,"type":36},{"date":405,"type":36},"2026-06-05",{"date":407,"type":21},"2026-10-15",{"name":42,"class":43},{"id":410,"slug":411,"hasResults":12,"nctId":412,"briefTitle":413,"officialTitle":414,"acronym":415,"eligibilityCriteria":416,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":4,"enrollmentInfo":417,"targetDuration":4,"studyType":22,"phases":419,"briefSummary":420,"conditions":421,"keywords":424,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":379,"lastUpdatePostDateStruct":429,"startDateStruct":430,"completionDateStruct":432,"leadSponsor":434,"locationsCount":44},"100642152","mobile-health-application-for-family-caregivers-in-home-palliative-care-100642152","NCT07654998","Mobile Health Application for Family Caregivers in Home Palliative Care","Effectiveness of a Mobile Health Application for Family Caregivers of Patients Receiving Home Palliative Care: A Randomized Controlled Trial","CARE-Mobile","Inclusion Criteria:\n\n* Family caregiver of a patient receiving home palliative care services.\n* Aged 18 years or older.\n* Providing unpaid care to the patient for at least 3 months.\n* Able to read and understand Turkish.\n* Owns or has regular access to a smartphone compatible with the mobile application.\n* Willing to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Professional or paid caregivers.\n* Participation in another structured caregiver support program during the study period.\n* Cognitive, visual, or hearing impairments that would prevent effective use of the mobile application.\n* Inability to complete study assessments.\n* Withdrawal of consent at any stage of the study.",{"count":418,"type":21},120,[24],"Family caregivers play a central role in providing daily care for patients receiving home palliative care. However, caregiving responsibilities may lead to increased burden, stress, and difficulties in symptom management and care coordination. Mobile health (mHealth) interventions may provide accessible education, symptom monitoring, and decision-support resources to improve caregiver outcomes and patient care.\n\nThe aim of this randomized controlled trial is to evaluate the effectiveness of a mobile health application developed for family caregivers of patients receiving home palliative care. The primary outcome is caregiver competence. Secondary outcomes include caregiver burden, self-efficacy, patient symptom burden, emergency department visits, and hospitalizations.\n\nA total of 120 family caregivers will be randomly assigned to either the intervention group, which will use the mobile health application for 6 weeks in addition to usual care, or the control group, which will receive usual care alone. Outcomes will be assessed at baseline, post-intervention (Week 6), and follow-up (Week 18).",[368,422,423],"Cancer","Caregiver",[425,426,427,428,369],"Mobile Health","Family Caregiver","Home Palliative Care","Caregiver Competence",{"date":381,"type":36},{"date":431,"type":36},"2026-06-10",{"date":433,"type":21},"2026-10-30",{"name":42,"class":43},{"id":436,"slug":437,"hasResults":12,"nctId":438,"briefTitle":439,"officialTitle":440,"acronym":4,"eligibilityCriteria":441,"healthyVolunteers":12,"sex":17,"minAge":442,"maxAge":4,"enrollmentInfo":443,"targetDuration":4,"studyType":22,"phases":445,"briefSummary":446,"conditions":447,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":379,"lastUpdatePostDateStruct":451,"startDateStruct":452,"completionDateStruct":454,"leadSponsor":456,"locationsCount":44},"100618360","clinical-radiographic-and-digital-evaluation-of-the-effects-of-autogenous-grafts-on-peri-implant-mucosa-100618360","NCT07330609","Clinical, Radiographic, and Digital Evaluation of the Effects of Autogenous Grafts on Peri-implant Mucosa","Clinical, Radiographic, and Digital Evaluation of the Effects of Autogenous Grafts Harvested From Different Palatal Sites and Applied During Second-stage Implant Surgery on the Peri-implant Mucosa","Inclusion Criteria:\n\n* Age over 18 years\n* Systemically healthy patients\n* Presence of premolar or molar tooth loss in the mandible\n* Adequate mesiodistal and interocclusal space for implant and restoration placement\n* At least four months elapsed since tooth extraction\n* Alveolar bone width of at least 6 mm and sufficient alveolar bone height to allow implant placement without compromising anatomical structures\n* Full-mouth plaque and bleeding scores less than 20%\n* Presence of opposing teeth in occlusion\n* Keratinized mucosa width in the relevant region less than 2 mm\n* Keratinized mucosa thickness in the relevant region of 2 mm or less\n* Presence of a healthy second premolar in the maxilla\n* Provision of written informed consent and permission for the use of data for research purposes\n\nExclusion Criteria:\n\n* Poor oral hygiene\n* Uncontrolled periodontal disease\n* Pregnancy or lactation at any stage of the study\n* Uncontrolled diabetes mellitus\n* Immunocompromised patients\n* Previous radiotherapy to the head and neck region\n* Diseases or medications affecting bone metabolism\n* Antibiotic use within the three months prior to the procedure\n* Smoking more than 10 cigarettes per day\n* Pre- or simultaneous bone augmentation prior to implant placement\n* Lack of primary stability at the time of implant placement","18 Months",{"count":444,"type":21},30,[24],"This study aims to evaluate the effects of autogenous grafts harvested from different palatal regions on the peri-implant mucosa when applied during second-stage dental implant surgery.\n\nClinical, radiographic, and digital assessment methods will be used to investigate the early effects of these grafts on peri-implant mucosal width and thickness. In addition, peri-implant tissue health and patient-reported outcomes will be evaluated to compare the effectiveness of the grafting techniques in peri-implant soft tissue management.",[448,449,450],"Peri-implant Health","Free Gingival Graft","Peri-implant Mucositis",{"date":281,"type":36},{"date":453,"type":36},"2026-02-02",{"date":455,"type":21},"2027-11-01",{"name":42,"class":43},{"id":458,"slug":459,"hasResults":12,"nctId":460,"briefTitle":461,"officialTitle":462,"acronym":463,"eligibilityCriteria":464,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":104,"enrollmentInfo":465,"targetDuration":4,"studyType":22,"phases":467,"briefSummary":468,"conditions":469,"keywords":472,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":480,"lastUpdatePostDateStruct":481,"startDateStruct":483,"completionDateStruct":484,"leadSponsor":486,"locationsCount":44},"100647411","970-nm-diode-laser-versus-liquid-nitrogen-cryotherapy-in-maxillary-labial-frenectomy-100647411","NCT07708389","970-nm Diode Laser Versus Liquid Nitrogen Cryotherapy in Maxillary Labial Frenectomy","Comparison of Salivary Cortisol Response and Early Postoperative Outcomes Following 970-nm Diode Laser and Liquid Nitrogen Cryotherapy in Maxillary Labial Frenectomy: A Randomized Single-Blind Clinical Trial","MLF-DL-KRYO","Inclusion Criteria:\n\n* Age between 18 and 65 years.\n* Systemically healthy, ASA I status.\n* Clinical indication for maxillary labial frenectomy.\n* Ability to attend postoperative follow-up visits.\n* Provision of written informed consent.\n\nExclusion Criteria:\n\n* Systemic or local corticosteroid use within the last 6 months.\n* Endocrine disease that may affect cortisol levels.\n* Pregnancy or lactation.\n* Active oral infection.\n* Chronic analgesic or anti-inflammatory drug use.\n* Psychiatric medication use.\n* Smoking.\n* ASA II or higher systemic status.\n* Inability to attend follow-up visits.\n* Refusal to participate in the study.",{"count":466,"type":21},40,[24],"This prospective, randomized, single-blind, assessor-blinded, parallel-group clinical trial aims to compare the effects of 970-nm diode laser and liquid nitrogen cryotherapy in patients requiring maxillary labial frenectomy.\n\nThe primary objective is to compare the change in salivary cortisol levels from baseline to postoperative day 2 between the two treatment groups. Secondary objectives include comparison of postoperative pain, edema, interincisal mouth opening, analgesic consumption, operation duration, state anxiety, clinical wound healing, and adverse events.\n\nEligible adult patients with an indication for maxillary labial frenectomy will be randomly assigned to receive either 970-nm diode laser frenectomy or liquid nitrogen cryotherapy. Salivary cortisol samples and clinical outcomes will be assessed during the early postoperative follow-up period.",[470,471],"Maxillary Labial Frenulum Abnormality","Hypertrophic Maxillary Labial Frenulum",[473,474,475,476,477,478,479],"Maxillary labial frenectomy","Diode laser","970-nm diode laser","Liquid nitrogen cryotherapy","Salivary cortisol","Postoperative pain","Wound healing","2026-07-13",{"date":482,"type":36},"2026-07-16",{"date":263,"type":21},{"date":485,"type":21},"2027-05-21",{"name":42,"class":43},{"id":488,"slug":489,"hasResults":12,"nctId":490,"briefTitle":491,"officialTitle":491,"acronym":4,"eligibilityCriteria":492,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":104,"enrollmentInfo":493,"targetDuration":4,"studyType":22,"phases":494,"briefSummary":495,"conditions":496,"keywords":497,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":499,"lastUpdatePostDateStruct":500,"startDateStruct":502,"completionDateStruct":504,"leadSponsor":506,"locationsCount":44},"100631930","the-effect-of-internal--or-external-focused-exercise-training-administered-in-conjunction-with-a-cognitive-task-on-walking-balance-and-cognitive-functions-in-individuals-with-multiple-sclerosis-100631930","NCT07507084","The Effect of Internal- or External-Focused Exercise Training, Administered in Conjunction With a Cognitive Task, on Walking, Balance, and Cognitive Functions in Individuals With Multiple Sclerosis","Inclusion Criteria:\n\n* Diagnosis of Multiple Sclerosis according to the revised McDonald criteria\n* Aged between 20 and 60 years\n* Ability to understand and follow simple instructions\n* Ability to stand and walk independently or with an assistive device\n* Ability to speak and understand Turkish\n* Score of ≥21 on the Montreal Cognitive Assessment (MoCA)\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* MS relapse within the last 30 days\n* Presence of any other neurological disease besides Multiple Sclerosis\n* Any musculoskeletal condition that may affect walking or balance\n* History of uncontrolled cardiorespiratory conditions within the last 3 months (e.g., hypertension, arrhythmia, tachycardia, or acute cardiopulmonary events)\n* Severe visual or hearing impairment",{"count":466,"type":21},[24],"This interventional clinical trial aims to investigate the effects of internal and external focus-based exercise training combined with cognitive dual-task training in individuals diagnosed with multiple sclerosis. The primary objective is to determine whether these exercise approaches improve gait, balance, and cognitive functions.\n\nThe main research questions are:\n\nDoes dual-task training combined with internal focus-based exercises improve gait, balance, and cognitive performance? Does dual-task training combined with external focus-based exercises lead to greater improvements compared to internal focus strategies?\n\nParticipants will be divided into two groups, and the researchers will compare the effects of internal focus-based and external focus-based dual-task exercise training on functional outcomes.\n\nParticipants will:\n\nPerform structured exercise sessions under the supervision of a physiotherapist Engage in dual-task activities by combining motor exercises with simple cognitive tasks (e.g., backward counting, word generation) Participate in an 8-week training program, with sessions held twice a week lasting approximately 45-60 minutes Undergo assessments of gait, balance, and cognitive function before and after the intervention\n\nThis study does not involve invasive procedures or biological sample collection. The findings are expected to contribute to the development of more effective dual-task rehabilitation strategies for individuals with multiple sclerosis.",[59],[498],"multiple sclerosis, dual-task training, internal focus, external focus, gait, balance, cognitive function, exercise therapy","2026-06-29",{"date":501,"type":36},"2026-07-01",{"date":503,"type":36},"2026-03-15",{"date":505,"type":21},"2028-08-30",{"name":42,"class":43},{"id":508,"slug":509,"hasResults":12,"nctId":510,"briefTitle":511,"officialTitle":512,"acronym":4,"eligibilityCriteria":513,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":104,"enrollmentInfo":514,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":515,"conditions":516,"keywords":518,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":525,"startDateStruct":527,"completionDateStruct":529,"leadSponsor":531,"locationsCount":44},"100634778","predictors-of-functional-status-in-chronic-neck-pain-100634778","NCT07544108","Predictors of Functional Status in Chronic Neck Pain","Predictors of Functional Status in Chronic Non-Spesific Neck Pain","Inclusion Criteria:\n\n* patients aged 18-65\n* patients have experienced non-specific neck pain for at least 3 months, patients who are literate, and no cognitive impairment.\n\nExclusion Criteria:\n\n* patients with serious and secondary musculoskeletal diseases (inflammatory, neuropathic and malignancy)\n* patiens who have undergone spinal and abdominal surgery and trauma\n* patients who smoke\n* patients if any lung disease that will affect respiration,\n* patients with a body mass index greater than 40\n* patients who cannot operate.",{"count":83,"type":21},"Although it has been reported that these problems seen together with neck pain are related to functional limitations and disability, there is still insufficient evidence regarding the relationship between factors affecting functional status and chronic neck pain symptoms in individuals with chronic neck pain. Furthermore, a mixed methodology approach has not been used to comprehensively investigate this relationship. Identifying factors affecting functional status in CNP will help guide the prevention, treatment, and management of neck pain. Therefore, the aim of this study is to investigate the relationships between functional status and psychosocial and bodily functions in CNP.",[517],"Neck Pain",[519,520,521,522,523],"Chronic neck pain","neck disability","maximum inspiratory pressure","maximum expiratory pressure","anxiety","2026-04-22",{"date":526,"type":36},"2026-04-27",{"date":528,"type":36},"2025-10-20",{"date":530,"type":21},"2026-06-20",{"name":42,"class":43},{"id":533,"slug":534,"hasResults":12,"nctId":535,"briefTitle":536,"officialTitle":537,"acronym":4,"eligibilityCriteria":538,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":104,"enrollmentInfo":539,"targetDuration":4,"studyType":22,"phases":540,"briefSummary":541,"conditions":542,"keywords":544,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":548,"lastUpdatePostDateStruct":549,"startDateStruct":551,"completionDateStruct":553,"leadSponsor":555,"locationsCount":44},"100583405","effect-of-motor-imagery-training-on-pain-functionality-proprioception-and-kinesiophobia-in-partial-rotator-cuff-tear-100583405","NCT06875895","Effect of Motor Imagery Training on Pain, Functionality, Proprioception and Kinesiophobia in Partial Rotator Cuff Tear","Effect of Motor Imagery Training on Pain, Functionality, Proprioception and Kinesiophobia in Patients With Partial Rotator Cuff Tears","Inclusion Criteria:\n\n* Partial rotator cuff tear diagnosis.\n* Between the ages of 18-65\n* Patients experiencing pain for at least 4 weeks.\n* Having a valid score on the Mini Mental Test (\\>24)\n* Those without a history of any neurological or serious psychological illness.\n* Those who have not participated in a previous study on motor imagery training\n\nExclusion Criteria:\n\n* Complete rotator cuff tear or conditions requiring surgical intervention,\n* Participants who have received treatment with corticosteroids by any means in the previous 6 months,\n* Participants who have a rotator cuff tear due to acute traumatic conditions (proximal humerus fracture).",{"count":83,"type":21},[24],"The aim of this study is to investigate the effects of motor imagery training on pain, functionality, proprioception and kinesiophobia in patients with partial rotator cuff tears. Participants will be randomly assigned to traditional physiotherapy and motor imagery groups. Interventions will be performed with a physiotherapist for a total of 20 sessions for 4 weeks, 5 days a week. The intervention program will be determined by the Specialist Physical Therapy Physician. Data will be collected before the study, at the end of the training in the 4th week and at the 8th week (follow-up evaluation). Motor imagery ability will be assessed with the Movement Imagery Questionnaire (MIQ-R), pain will be assessed with the Numerical Assessment Scale for functionality with the DASH, proprioception will be assessed with the inclinometer and kinesiophobia will be assessed with the Tampa Kinesiophobia Scale.",[543],"Rotator Cuff Tears",[545,546,547],"Rotator Cuff","Exercise therapy","Imagery","2026-04-20",{"date":550,"type":36},"2026-04-23",{"date":552,"type":36},"2025-01-16",{"date":554,"type":21},"2026-05-03",{"name":42,"class":43},{"id":557,"slug":558,"hasResults":12,"nctId":559,"briefTitle":560,"officialTitle":560,"acronym":561,"eligibilityCriteria":562,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":104,"enrollmentInfo":563,"targetDuration":55,"studyType":56,"phases":4,"briefSummary":564,"conditions":565,"keywords":567,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":572,"lastUpdatePostDateStruct":573,"startDateStruct":574,"completionDateStruct":576,"leadSponsor":577,"locationsCount":44},"100634806","validity-and-reliability-of-the-turkish-version-of-the-breathing-vigilance-questionnaire-100634806","NCT07544472","Validity and Reliability of the Turkish Version of the 'Breathing Vigilance Questionnaire'","Breathe-VQ","Inclusion Criteria:\n\n* individuals without a self-reported diagnosis of respiratory and\u002For cardiac problems\n* individuals without a COVID-19 diagnosis and\u002For chronic COVID syndrome (\"long COVID\") within the last 3 months (primary respiratory dysfunction is excluded as we are dealing with this)\n* individuals who can read and write in Turkish\n\nExclusion Criteria:\n\n* Individuals with symptomatic heart disease, a history of lung surgery, neurological disorders, and malignancies that may affect exercise performance, and those with severe cognitive impairment who have difficulty understanding and completing the questionnaire items will be excluded from the study.",{"count":54,"type":21},"In the literature, assessment questionnaires related to dyspnea measure beliefs about breathing-related symptoms but do not directly measure breath awareness. For this purpose, the Breath Vigilance Questionnaire (BVQ) is a subjective questionnaire developed from the Pain Awareness Questionnaire that directly measures breath-specific awareness and includes questions evaluating the interaction between conscious monitoring and control of breathing and anxiety. The questionnaire, consisting of 6 questions, was developed on healthy individuals and its validity and reliability were established. It uses a 5-point Likert scale from 1 (never) to 5 (always), with scores ranging from 6 to 30, and higher scores indicate higher breath awareness .\n\nThe reliability and validity of the Turkish version of the Breath Vigilance Questionnaire will assist researchers in assessing dysfunctional breathing and developing treatment strategies by evaluating breath awareness. Therefore, the study aimed to investigate the validity and reliability of the Turkish version.",[566],"Healthy Adult Participants",[568,569,570,571],"breathing","Awareness","respiration","vigilance","2026-04-15",{"date":524,"type":36},{"date":575,"type":21},"2026-04-10",{"date":431,"type":21},{"name":42,"class":43},{"id":579,"slug":580,"hasResults":12,"nctId":581,"briefTitle":582,"officialTitle":583,"acronym":4,"eligibilityCriteria":584,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":81,"enrollmentInfo":585,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":587,"conditions":588,"keywords":592,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":597,"lastUpdatePostDateStruct":598,"startDateStruct":600,"completionDateStruct":602,"leadSponsor":604,"locationsCount":44},"100621827","hba1c-levels-and-gastric-emptying-assessed-by-gastric-ultrasound-100621827","NCT07375680","HbA1c Levels and Gastric Emptying Assessed by Gastric Ultrasound","Evaluation of the Effect of Hemoglobin A1c Levels on Gastric Emptying Assessed by Gastric Ultrasound","Inclusion Criteria:\n\nAdults aged 18 to 70 years. ASA physical status I-III. Scheduled for elective surgery under general anesthesia. Ability to provide written informed consent.\n\nExclusion Criteria:\n\nScheduled for emergency surgery. Refusal or inability to provide informed consent. Pregnancy. Age \\\u003C18 years or \\>70 years. History of gastric surgery. Neuromuscular disease. Current use of opioid or anticholinergic medications.",{"count":586,"type":21},134,"Delayed gastric emptying increases the risk of pulmonary aspiration during general anesthesia. Diabetes mellitus and poor long-term glycemic control have been associated with impaired gastric motility. Hemoglobin A1c (HbA1c) is a marker of long-term glycemic control; however, its relationship with gastric emptying in surgical patients is not fully understood.\n\nThis prospective observational study aims to evaluate the association between HbA1c levels and gastric emptying using preoperative bedside gastric ultrasonography. Adult patients scheduled for elective surgery under general anesthesia will undergo gastric ultrasound examination after standard fasting. Gastric antral cross-sectional area and estimated gastric volume will be assessed and compared according to HbA1c levels.\n\nThe findings of this study may help improve preoperative risk stratification for aspiration and support individualized anesthetic management in patients with impaired glycemic control.",[589,590,591],"Delayed Gastric Emptying","Diabetes Mellitus","Pulmonary Aspiration",[593,594,595,596],"Hemoglobin A1c","Gastric Ultrasonography","General Anesthesia","Preoperative Assessment","2026-04-06",{"date":599,"type":36},"2026-04-08",{"date":601,"type":36},"2026-02-15",{"date":603,"type":21},"2026-09",{"name":42,"class":43},{"id":606,"slug":607,"hasResults":12,"nctId":608,"briefTitle":609,"officialTitle":610,"acronym":4,"eligibilityCriteria":611,"healthyVolunteers":12,"sex":17,"minAge":52,"maxAge":104,"enrollmentInfo":612,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":613,"conditions":614,"keywords":618,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":622,"lastUpdatePostDateStruct":623,"startDateStruct":625,"completionDateStruct":627,"leadSponsor":629,"locationsCount":44},"100561340","investigation-of-motor-imagery-ability-body-awareness-and-cognitive-functions-in-type-2-diabetes-mellitus-100561340","NCT06588894","Investigation of Motor Imagery Ability, Body Awareness and Cognitive Functions in Type 2 Diabetes Mellitus","Relationship Between Motor Imagery Ability, Body Awareness and Cognitive Functions in Individuals With Type 2 Diabetes Mellitus","Inclusion Criteria:\n\n* Being a type 2 DM patient between the ages of 18-65 for at least 5 years,\n* Being willing to participate in the study,\n* Not having any vision, hearing or speech problems that would prevent the tests from being performed.\n\nExclusion Criteria:\n\n* Having previous experience with Motor Imagery techniques or training,\n* Having any orthopedic problems that prevent walking,\n* Having a history of neurological disease,\n* People who are receiving any medication that affects the central nervous system will not be included in the study.",{"count":152,"type":21},"The aim of this study is to examine the relationship between motor imagery skills, body awareness and cognitive functions in individuals with Type 2 Diabetes mellitus.",[615,616,617],"Type 2 Diabetes Mellitus (T2DM)","Cognitive Function","Motor İmagery Ability",[619,620,621],"cognitive functions","motor imagery ability","type 2 diabetes mellitus","2026-03-09",{"date":624,"type":36},"2026-03-10",{"date":626,"type":36},"2024-10-14",{"date":628,"type":21},"2026-12-10",{"name":42,"class":43},""]