[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lahore University of Biological and Applied Sciences\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":570},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,56,0,25,[9,48,78,107,128,148,167,187,212,233,249,267,283,298,317,341,357,375,397,417,440,464,488,514,544],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100651483","effects-of-buteyko-breathing-versus-incentive-spirometry-on-oxygen-saturation-dyspnoea-exercise-tolerance-and-sputum-clearance-in-patients-with-smog-induced-pneumonia-100651483",false,"NCT07759583","Effects of Buteyko Breathing Versus Incentive Spirometry on Oxygen Saturation, Dyspnoea, Exercise Tolerance, and Sputum Clearance in Patients With Smog Induced Pneumonia","Inclusion Criteria:\n\nMale and female participants Age between 25-40 years Clinically diagnosed pneumonia Recent exposure to high air pollution levels (AQI threshold exceeded within the past 7 days) Resting oxygen saturation between 86-95% Ability to understand and perform breathing exercises -\n\nExclusion Criteria:\n\nRequirement for mechanical ventilation or ICU admission Hemodynamic instability Severe chronic respiratory disease such as COPD with hypercapnia Pneumothorax or massive hemoptysis Recent thoracic surgery or trauma Cognitive impairment affecting cooperation Pregnancy\n\n\\-","ALL","25 Years","40 Years",{"count":20,"type":21},62,"ESTIMATED","INTERVENTIONAL",[24],"NA","The current study will be a single-blind, parallel-group randomized controlled trial involving 62 patients diagnosed with smog-induced pneumonia. The study will compare the effects of Buteyko Breathing Technique (BBT) with Incentive Spirometry (IS) on respiratory outcomes.\n\nParticipants will be randomly assigned to two groups using a concealed allocation method. The experimental group will receive Buteyko Breathing Technique along with standard medical care, while the control group will receive Incentive Spirometry along with standard medical care.\n\nBoth interventions will be performed twice daily for approximately 20-30 minutes per session for seven days or until hospital discharge.\n\nPrimary outcomes will include oxygen saturation (SpO₂), dyspnoea severity, exercise tolerance, sputum clearance, and respiratory symptom burden. Assessments will be conducted at baseline (Day 0), mid-intervention (Day 3), post-intervention (Week 2), and follow-up (Week 4).\n\nThe study will be conducted at the pulmonary wards of Combined Military Hospital (CMH) and The Indus Hospital, Lahore.\n\nThe hypothesis is that Buteyko Breathing Technique may produce greater improvements in oxygen saturation, dyspnoea reduction, exercise tolerance, and sputum clearance compared with Incentive Spirometry in patients with smog-induced pneumonia.",[27,28],"Smog-Induced Pneumonia","Pneumonia",[30,31,32,33,34],"Buteyko Breathing Technique","Incentive Spirometry","Oxygen saturation","Pulmonary Rehabilitation","Smog-induced Pneumonia","RECRUITING","2026-08-06",{"date":38,"type":39},"2026-08-12","ACTUAL",{"date":41,"type":39},"2026-05-01",{"date":43,"type":21},"2026-10-15",{"name":45,"class":46},"Lahore University of Biological and Applied Sciences","OTHER",1,{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":12,"sex":16,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":65,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":47},"100649715","mind-body-pilates-vs-pressure-biofeedback-for-chronic-non-specific-low-back-pain-100649715","NCT07738965","Mind-Body Pilates vs Pressure Biofeedback for Chronic Non-Specific Low Back Pain","Effects of Mind-Body Pilates Versus Pressure Biofeedback on Pain,Core Strength and Quality of Life in Chronic Non-Specific Low Back Pain","Inclusion Criteria:\n\n* Age 40-55 years.\n* Diagnosed with chronic non-specific low back pain (pain lasting ≥12 weeks).\n* Numeric Rating Scale (NRS) pain score ≥3.\n* Able to understand study procedures and provide written informed consent.\n* Able to participate in the exercise program and attend treatment sessions.\n\nExclusion Criteria:\n\n* History of lumbar spine surgery within the past 12 months.\n* Serious spinal pathology (fracture, tumor, infection, inflammatory disease).\n* Neurological deficits or radiculopathy requiring surgical management.\n* Pregnancy.\n* Participation in a structured Pilates or core stabilization program within the previous 6 months.\n* Any medical condition that prevents safe participation in exercise.","55 Years",{"count":57,"type":21},66,[24],"Chronic Non-Specific Low Back Pain means pain in the lower back that lasts for more than 3 months and does not have a serious cause like a fracture, infection, or nerve damage. It is very common and affects many people at some point in their lives.\n\nThis type of back pain usually happens because the muscles that support your spine become weak or do not work properly. It can also be linked to poor posture, sitting too long, lack of exercise, stress, or anxiety. Over time, this can lead to stiffness, reduced movement, and difficulty doing daily activities.\n\nTreatment mainly focuses on exercise and staying active. Simple physiotherapy treatments like stretching, strengthening, and heat therapy can help reduce pain, but they may not fully improve the deeper muscles that support your back.\n\nTwo helpful exercise approaches are:\n\nMind-Body Pilates: This involves slow, controlled movements with proper breathing. It helps improve posture, strengthen core muscles, and reduce stress.\n\nPressure Biofeedback Training: This uses a small device to help you learn how to correctly activate deep abdominal muscles that support your spine.\n\nBoth methods can reduce pain and improve movement. Pilates focuses on whole-body control and relaxation, while biofeedback training focuses more on activating specific muscles.\n\nIn simple terms, regular exercise, good posture, and learning how to properly use your core muscles are key to managing long-term back pain and improving your quality of life.",[61,62,63,64],"Chronic Non Specific Low Back Pain","Pain","Core Strength","Quality of Life",[66,67,68],"Mind-Body Pilates","pressure biofeedback","chronic Non specific low back pain","NOT_YET_RECRUITING","2026-07-27",{"date":72,"type":39},"2026-07-31",{"date":74,"type":21},"2026-07-01",{"date":76,"type":21},"2026-11-30",{"name":45,"class":46},{"id":79,"slug":80,"hasResults":12,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":12,"sex":16,"minAge":18,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},"100649413","development-and-validation-of-mobile-application-for-upper-limb-function-in-stroke-survivors-100649413","NCT07734818","Development and Validation of Mobile Application for Upper Limb Function in Stroke Survivors","Inclusion Criteria:\n\nSubacute and chronic stroke patient \\> 3 months post stroke. Modified Ashworth scale \\\u003C3 MOCA \\> 24. An ability to understand the command First ever stroke Grade II, III, IV on Functional mobility Scale Able to use and comprehend smart phone.\n\nExclusion Criteria:\n\nPosterior circulation stroke. Vestibular disorders, paroxysmal vertigo Presence of other neurological conditions such as neglect, hemianopsia and pushing syndrome Presence of orthopedic diseases involving the upper limb","60 Years",{"count":86,"type":21},20,[24],"impairments that limit functional independence. This study aims to develop and validate a bilingual (English and Urdu) mobile application to improve upper limb function in stroke survivors through structured, task-oriented exercises. It will be conducted in two phases: app development and validation, followed by a pilot randomized controlled trial. A total of 20 participants will be recruited using convenience sampling and randomly assigned to either a clinical exercise-based group or an app-based training group, with allocation concealment ensured through sealed envelopes. The study will follow a double-blinded design, where both participants and the outcome assessor will be blinded. Outcomes will be measured using the Wolf Motor Function Test (WMFT), Fugl- Meyer Assessment (FMA), and Nine Hole Peg Test (NHPT). The study aims to provide an accessible, evidence-based digital solution to enhance functional recovery and improve quality of life in stroke survivors.",[90],"Stroke",[92,93,94,95,96,97],"Mobile application","Stroke survivors","Stroke rehabilitation for upper limb","stroke rehabilitation","personalized interventions","technology integration","2026-07-24",{"date":100,"type":39},"2026-07-29",{"date":102,"type":21},"2026-08-15",{"date":104,"type":21},"2027-02-10",{"name":45,"class":46},2,{"id":108,"slug":109,"hasResults":12,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":22,"phases":117,"briefSummary":118,"conditions":119,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":125,"leadSponsor":127,"locationsCount":47},"100649231","effects-of-myofascial-release-versus-dry-cupping-on-pain-muscle-length-and-functional-disability-in-it-professionals-with-trapezitis-100649231","NCT07731763","Effects of Myofascial Release Versus Dry Cupping on Pain, Muscle Length, and Functional Disability in IT Professionals With Trapezitis.","\"Effects of Myofascial Release Versus Dry Cupping on Pain, Muscle Length, and Functional Disability in IT Professionals With Trapezitis\"","Inclusion Criteria:\n\nIT professionals aged 20-65 years diagnosed with trapezitis (upper trapezius myofascial pain) characterized by pain and tenderness in the upper trapezius region for at least 4 weeks. Participants must have a pain intensity of ≥3 on the Numeric Pain Rating Scale (NPRS), exhibit restricted cervical range of motion or reduced upper trapezius muscle length as assessed using a goniometer. Functional disability must be present as indicated by a Neck Disability Index (NDI) score within the mild to moderate range (e.g., 10-28%), and be engaged in computer-based work for a minimum of 6 hours per day. Both male and female participants who provide informed consent will be included.\n\nExclusion Criteria:\n\nIndividuals with a history of cervical spine pathology including disc herniation, radiculopathy, or spondylosis with neurological involvement; previous trauma or surgery involving the cervical spine, shoulder girdle, or upper thoracic region; presence of symptomatic or inflammatory musculoskeletal conditions (e.g., rheumatoid arthritis, ankylosing spondylitis, fibromyalgia); neurological disorders affecting the upper limb or cervical region (e.g., peripheral neuropathy, myelopathy); skin conditions or contraindications to cupping therapy (e.g., open wounds, active infections, eczema, psoriasis); bleeding disorders or current anticoagulant therapy; pregnancy; and inability to comply with the treatment protocol or follow-up assessments will be excluded.","65 Years",{"count":116,"type":21},52,[24],"This study aims to evaluate the effectiveness of two physiotherapy techniques-Myofascial Release and Dry Cupping-in improving pain, muscle length, and functional disability in IT professionals with trapezitis. Trapezitis is a common musculoskeletal condition caused by prolonged static postures and repetitive strain, leading to neck and shoulder pain, reduced muscle flexibility, and functional limitations that affect daily activities and work performance. Although both myofascial release and dry cupping are commonly used in clinical practice, limited evidence exists comparing their effectiveness in this population. Participants diagnosed with trapezitis will be randomized into two groups: Group 1 will receive myofascial release along with routine physical therapy, and Group 2 will receive dry cupping therapy along with routine physical therapy. The interventions will be administered multiple times per week over a specified duration, and participants will be assessed before and after treatment. Outcome measures will include pain intensity using the Numeric Pain Rating Scale (NPRS), muscle length of the upper trapezius, and functional disability using the Neck Disability Index (NDI). The study will compare the effects of both interventions, focusing on pain reduction, improvement in muscle flexibility, and enhancement of functional ability. The findings may help in identifying the more effective treatment approach and contribute to improved management strategies for trapezitis among IT professionals.",[120],"Trapezitis","2026-07-23",{"date":123,"type":39},"2026-07-28",{"date":100,"type":21},{"date":126,"type":21},"2026-09-30",{"name":45,"class":46},{"id":129,"slug":130,"hasResults":12,"nctId":131,"briefTitle":132,"officialTitle":132,"acronym":4,"eligibilityCriteria":133,"healthyVolunteers":12,"sex":134,"minAge":135,"maxAge":18,"enrollmentInfo":136,"targetDuration":4,"studyType":22,"phases":138,"briefSummary":139,"conditions":140,"keywords":142,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":144,"startDateStruct":145,"completionDateStruct":146,"leadSponsor":147,"locationsCount":47},"100649195","effects-of-barre-based-core-stability-with-and-without-tupler-technique-on-core-strength-inter-recti-distance-and-pelvic-floor-function-among-diastasis-recti-abdominis-patients-100649195","NCT07731724","Effects of Barre-Based Core Stability With and Without Tupler Technique on Core Strength, Inter Recti Distance, and Pelvic Floor Function Among Diastasis Recti Abdominis Patients","Inclusion Criteria\n\n* Women aged 18-40 years\n* Postpartum period between 6-12 months\n* Diagnosed with stage I-II Diastasis Recti Abdominis\n* Presence of symptoms such as abdominal weakness or back pain\n* Ability to follow exercise instructions Exclusion Criteria\n* Stage III Diastasis Recti Abdominis\n* Severe hernias or significant pelvic floor dysfunction\n* Neurological, cardiovascular, or systemic conditions contraindicating exercise\n* History of abdominal surgery or trauma affecting the abdominal wall","FEMALE","18 Years",{"count":137,"type":21},58,[24],"This study will be a single blind, parallel group randomized controlled trial designed to evaluate the effectiveness of Barre-based core stability training with and without the Tupler Technique in postpartum women with Diastasis Recti Abdominis. A total of 58 eligible participants will be recruited from postpartum care units and randomly assigned in a 1:1 allocation ratio to either an experimental group receiving Barre-based core stability training combined with the Tupler Technique or a control group receiving Barre-based core stability training alone.\n\nBoth interventions will be delivered under supervised conditions three times per week for 8 weeks, with each session lasting approximately 30-45 minutes. The Barre-based program focuses on controlled low impact movements aimed at improving deep core muscle activation, postural alignment, and neuromuscular coordination. The experimental group will additionally receive the Tupler Technique, which includes abdominal splinting, progressive core strengthening exercises, and neuromuscular re-education targeting approximation of the rectus abdominis muscles and improved abdominal wall function.\n\nOutcome measures include inter-recti distance, core strength, and pelvic floor function. Secondary outcomes include postural stability and functional performance. Assessments will be conducted at baseline, mid-intervention (week 4), post-intervention (week 8), and follow-up (week 12) by blinded outcome assessors to minimize bias.\n\nThe purpose of this trial is to determine whether combining the Tupler Technique with Barre-based core stability training provides superior improvements in abdominal separation, core strength, pelvic floor function, and functional ability compared with Barre-based training alone in postpartum women.",[141],"Diastasis Recti Abdominis (Postpartum)",[143],"Diastasis Recti Abdominis, Postpartum, Core Stability, Barre Training, Tupler Technique, Inter-Recti Distance, Pelvic Floor",{"date":123,"type":39},{"date":41,"type":39},{"date":43,"type":21},{"name":45,"class":46},{"id":149,"slug":150,"hasResults":12,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":4,"eligibilityCriteria":154,"healthyVolunteers":12,"sex":16,"minAge":155,"maxAge":114,"enrollmentInfo":156,"targetDuration":4,"studyType":22,"phases":158,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":163,"startDateStruct":164,"completionDateStruct":165,"leadSponsor":166,"locationsCount":47},"100649101","effects-of-pressure-biofeedback-training-versus-bolster-foam-roll-training-for-pain-muscles-activation-and-quality-of-life-among-knee-osteoarthritis-patients-100649101","NCT07731737","Effects of Pressure Biofeedback Training Versus Bolster Foam Roll Training for Pain, Muscles Activation, and Quality of Life Among Knee Osteoarthritis Patients","Effects of Pressure Biofeedback Training Versus Bolster Foam Roll Training for Pain, Muscle Activation and Quality of Life Among Knee Osteoarthritis Patients","Inclusion Criteria:\n\n* Patient diagnosis with Grade II knee Osteoarthritis.\n\nAge between 45 and 65 years, encompassing the typical onset of symptomatic OA.\n\nBoth genders Male and Female are included.\n\nSymptomatic patients meeting the following American College of Rheumatology criteria: average pain score ≥ 3 in the last week on the numerical rating scale, morning stiffness \\\u003C 30 min, and joint crepitus\n\nExclusion Criteria:\n\nHistory of knee surgery (TKA, HTO, ACLR) or arthroscopy in the affected knee within the last 6 months.\n\nIntra-articular corticosteroid or hyaluronic acid injections within the last 3 months.\n\nNeurological conditions affecting lower limb motor control (e.g., Stroke, Parkinson's, Radiculopathy).\n\nAcute infection, tumor, or fracture around the knee joint.\n\nSevere cognitive impairment or inability to follow visual\u002Ftactile cues.\n\n\\-","45 Years",{"count":157,"type":21},48,[24],"The current study will be a single-blinded, two-arm parallel group randomized clinical trial involving 48 participants. The trial will compare Pressure Biofeedback training with Bolster Foam Roll training. Interventions will be delivered three times per week for eight weeks. The primary outcomes will include pain intensity, functional status, and muscle activation. Assessments will be conducted at baseline (week 0), mid-intervention (week 4), post-intervention (week 8), and follow-up (week 12). The study will be conducted at the outpatient departments of Sir Ganga Ram Hospital (SGRH) and Mayo Hospital Lahore. The hypothesis is that there is a difference between Pressure Biofeedback Training and Bolster Foam Feedback Training regarding pain reduction, muscle activation, and patient-reported quality of life compared to Bolster Foam rolling training among knee osteoarthritis patients.",[161,162],"Knee Osteoarthritis (Knee OA)","Knee Arthritis, Osteoarthritis",{"date":123,"type":39},{"date":41,"type":39},{"date":43,"type":21},{"name":45,"class":46},{"id":168,"slug":169,"hasResults":12,"nctId":170,"briefTitle":171,"officialTitle":171,"acronym":4,"eligibilityCriteria":172,"healthyVolunteers":12,"sex":16,"minAge":173,"maxAge":84,"enrollmentInfo":174,"targetDuration":4,"studyType":22,"phases":176,"briefSummary":177,"conditions":178,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":106},"100648664","effects-of-myokinetic-stretching-technique-and-post-facilitation-stretching-on-pain-range-of-motion-and-functional-disability-in-patients-with-cervical-radicular-pain-100648664","NCT07724470","Effects of Myokinetic Stretching Technique and Post Facilitation Stretching on Pain, Range of Motion, and Functional Disability in Patients With Cervical Radicular Pain","Inclusion Criteria:\n\n1. Both male and female gender\n2. Age 30 to 60 years with a +ve spurling test and radiating arm pain for more than 4 weeks\n3. Unilateral cervical radicular pain\n4. +ve upper limb tension test and neck disability index \\\u003C50%\n\nExclusion Criteria:\n\n1. History of cervical spinal surgery\n2. Severe facet joint osteoarthritis\n3. History of fracture in the head and neck region\n4. Patient with cognitive dysfunction or mental illness, severe cardiovascular, cerebrovascular, liver, or kidney dysfunction\n5. History of dizziness, vertigo, and vomiting\n6. Osteoporosis and prolonged use of steroids\n7. Cervical myelopathy, tumor, or infectious disease","30 Years",{"count":175,"type":21},40,[24],"Cervical radicular pain (CRP) is a musculoskeletal condition characterized by neck pain radiating to the upper limb due to compression or irritation of cervical nerve roots. It significantly affects daily activities, cervical mobility, and overall quality of life. Conventional physical therapy focuses on reducing pain and improving function; however, there is limited evidence comparing the effectiveness of different stretching techniques used in clinical practice.\n\nThis randomized controlled trial aims to compare the effectiveness of Myokinetic Stretching Technique (MST) and Post Facilitation Stretching (PFS) on pain intensity, cervical range of motion, and functional disability in patients with cervical radicular pain.\n\nA total of 70 participants with cervical radicular pain (\\>4 weeks) will be randomly allocated into two groups:\n\nGroup A (Myokinetic Stretching Technique Group) - receiving MST along with conventional therapy including hot pack application, cervical isometric exercises, neurodynamic gliding, and continuous cervical traction.\n\nGroup B (Post Facilitation Stretching Group) - receiving Post Facilitation Stretching along with the same conventional therapy.\n\nThe intervention will be conducted for 4 weeks, with 3 sessions per week on alternate days, each session lasting approximately 45 minutes.\n\nOutcome measures will include:\n\nPain intensity assessed using the Visual Analogue Scale (VAS) Cervical range of motion measured using a goniometer Functional disability assessed using the Neck Disability Index (NDI)\n\nThis study aims to determine the more effective stretching technique for reducing pain, improving cervical mobility, and enhancing functional outcomes, thereby supporting evidence-based physiotherapy practice in managing cervical radicular pain.",[179],"Cervical Radicular Pain","2026-07-21",{"date":98,"type":39},{"date":183,"type":39},"2026-06-29",{"date":185,"type":21},"2026-09-15",{"name":45,"class":46},{"id":188,"slug":189,"hasResults":12,"nctId":190,"briefTitle":191,"officialTitle":191,"acronym":4,"eligibilityCriteria":192,"healthyVolunteers":12,"sex":16,"minAge":135,"maxAge":18,"enrollmentInfo":193,"targetDuration":4,"studyType":22,"phases":195,"briefSummary":196,"conditions":197,"keywords":199,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":206,"startDateStruct":208,"completionDateStruct":209,"leadSponsor":211,"locationsCount":47},"100644340","effects-of-blood-flow-restriction-training-and-instrument-assisted-soft-tissue-mobilization-for-pain-strength-range-of-motion-and-kinesiophobia-among-acl-reconstruction-patients-100644340","NCT07662850","Effects of Blood Flow Restriction Training and Instrument-Assisted Soft Tissue Mobilization for Pain, Strength, Range of Motion, and Kinesiophobia Among ACL Reconstruction Patients.","Inclusion Criteria:\n\n* Age between 18 and 40 years.\n* Both genders.\n* Undergoing Primary Unilateral ACLR (using autologous tendon graft).\n* Medically cleared for low load rehabilitation (Wound healed, stable graft per surgeon).\n* Active knee flexion of ≥100° on the operative limb.\n* 8-16 weeks after reconstructive surgery.\n* Willing to comply with all rehabilitation sessions and follow up assessments; give informed consent\n\nExclusion Criteria:\n\n* Significant meniscectomy requiring protected weight-bearing\n* Active DVT, vascular disease, uncontrolled hypertension or other BFR contraindications\n* Patients exhibiting extension lag (inability to achieve full active knee extension) on the operated limb.\n* Neuromuscular disorders\n* Skin lesions preventing IASTM\n* Pregnancy\n* Contraindications to exercise",{"count":194,"type":21},46,[24],"This randomized clinical trial aims to compare the effects of Blood Flow Restriction Training (BFR) and Instrument-Assisted Soft Tissue Mobilization (IASTM) on pain, quadriceps muscle strength, knee range of motion (ROM), and kinesiophobia in patients following anterior cruciate ligament reconstruction (ACLR). ACLR patients commonly experience persistent muscle weakness, limited ROM, pain, and fear of movement, which can delay functional recovery and return to activity. A total of 46 participants (8-16 weeks post-ACLR) will be randomly allocated into two groups: a BFR group and an IASTM group. Both groups will receive interventions twice weekly for 8 weeks alongside standard physiotherapy. The BFR group will perform low-load resistance exercises under controlled vascular occlusion, while the IASTM group will receive soft tissue mobilization using specialized instruments combined with conventional rehabilitation. Outcome measures will include quadriceps strength (handheld dynamometer), pain (Numeric Pain Rating Scale), knee ROM (goniometer), and kinesiophobia (Tampa Scale of Kinesiophobia), assessed at baseline and post-intervention. The study aims to determine which intervention provides superior improvements in physical and psychological outcomes during early rehabilitation after ACL reconstruction.",[198],"ACL Reconstruction",[200,201,202,203,204,62,205],"Anterior Cruciate Ligament Reconstruction","Blood Flow Restriction Training","Instrument-Assisted Soft Tissue Mobilization","Quadriceps Strength","Range Of Motion","Kinesiophobia",{"date":207,"type":39},"2026-07-22",{"date":123,"type":21},{"date":210,"type":21},"2026-11-25",{"name":45,"class":46},{"id":213,"slug":214,"hasResults":12,"nctId":215,"briefTitle":216,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":12,"sex":16,"minAge":173,"maxAge":155,"enrollmentInfo":218,"targetDuration":4,"studyType":22,"phases":219,"briefSummary":220,"conditions":221,"keywords":223,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":229,"completionDateStruct":230,"leadSponsor":232,"locationsCount":47},"100648590","effects-of-stecco-fascial-manipulation-versus-muscle-energy-technique-on-pain-pressure-threshold-range-of-motion-and-disability-among-patients-with-sacroiliac-joint-dysfunction-100648590","NCT07723014","Effects of Stecco Fascial Manipulation Versus Muscle Energy Technique on Pain Pressure Threshold, Range of Motion and Disability Among Patients With Sacroiliac Joint Dysfunction","Inclusion Criteria:Age between 30-45.\n\n* Both male and female.\n* Participants with a medical diagnosis of SIJD (posterior innominate and anterior innominate), pain and tenderness at PSIS, Sacral Sulcus, Ilia.\n* Pain in the paraspinal muscles, gluteal or groin region, and radiating to either leg.\n* 3 Positive special tests for SIJD (Faber test, Thigh thrust test, Distraction test, compression test, and Gaenslen test).\n* Pain lasting for less than 3 months.\n\nExclusion Criteria:\n\n* Subjects with leg length discrepancy.\n* Subjects with any pathology observed in the lower extremity.\n* Subjects with pre-diagnosed tumors of the hip and spine.\n* Pregnancy.\n* Subjects with any history of recent trauma involving the lower limb.",{"count":116,"type":21},[24],"This study holds significant importance as it directly addresses the need for effective physiotherapy interventions in patients with sacroiliac joint dysfunction, a condition that contributes substantially to lower back pain and disability. By comparing the effects of Fascial Manipulation and Muscle Energy Technique on pain pressure threshold, disability, and range of motion, the study provides evidence-based guidance for clinicians in selecting the most appropriate treatment. The findings can help physiotherapists develop more targeted rehabilitation plans, improve patient outcomes, and reduce treatment time. Additionally, this research adds to the limited literature available on stecco fascial manipulation and muscle energy technique approaches for SI joint dysfunction and may encourage further studies to refine and expand conservative management strategies. Ultimately, the study benefits both healthcare professionals and patients by promoting more efficient, safe, and effective physiotherapy care.",[222],"Sacroiliac Joint Dysfunction",[224,225,226],"Stecco fascial manipulation","Muscle enrgy technique (MET)","Functional disability","2026-07-20",{"date":121,"type":39},{"date":41,"type":39},{"date":231,"type":21},"2026-10-10",{"name":45,"class":46},{"id":234,"slug":235,"hasResults":12,"nctId":236,"briefTitle":237,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":12,"sex":16,"minAge":239,"maxAge":18,"enrollmentInfo":240,"targetDuration":4,"studyType":22,"phases":241,"briefSummary":242,"conditions":243,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":245,"startDateStruct":246,"completionDateStruct":247,"leadSponsor":248,"locationsCount":47},"100648569","effects-of-thoracic-spine-and-cervical-spine-mobilization-on-pain-functional-disability-and-quality-of-life-in-patients-with-mechanical-neck-pain-100648569","NCT07723001","Effects of Thoracic Spine and Cervical Spine Mobilization on Pain, Functional Disability, and Quality of Life in Patients With Mechanical Neck Pain.","Inclusion Criteria:\n\nParticipants of both genders aged between 20 and 40 years with a clinical diagnosis of mechanical neck pain will be included in the study. Eligible participants must have a history of neck pain lasting more than 4 weeks (subacute to chronic) and demonstrate mild to moderate functional disability, defined by a Neck Disability Index (NDI) score between 10% and 50%.\n\nExclusion Criteria:\n\nParticipants will be excluded if they present with signs or symptoms of cervical radiculopathy or myelopathy, such as a positive Spurling's test accompanied by neurological deficits, dermatomal numbness, or myotome weakness. Individuals with a history of cervical spine fracture, dislocation, or spinal surgery, as well as those with inflammatory, infectious, or neoplastic spinal conditions, will also be excluded. Additional exclusion criteria include diagnosed osteoporosis or prolonged use of systemic corticosteroids, severe cervical spine instability or vertebrobasilar insufficiency, recent trauma to the cervical or thoracic spine within the past 6 months, presence of systemic neurological disorders, pregnancy, and current participation in another physiotherapy or clinical trial for neck pain.","20 Years",{"count":57,"type":21},[24],"Mechanical neck pain (MNP) is characterized as neck discomfort mostly originating from musculoskeletal components such as cervical facet joints, intervertebral discs, ligaments, and musculature, in the absence of indications of nerve root compression or severe pathological conditions. Although recent evidence supports the use of both cervical and thoracic mobilization for mechanical neck pain, there remains limited comparative research examining their combined or relative effects on pain, functional disability, and quality of life. A total of 66 Participants with mechanical neck pain (\\> 4 weeks) will be randomly allocated into two groups: Group A (Cervical spine Maitland mobilization group) will receive cervical spine Maitland mobilization throughout the 8-week intervention period, with sessions conducted twice weekly from pre-treatment to post-treatment assessment, Each session will be lasted approximately 30 minutes, consisting of manual therapy followed by standardized therapeutic exercises, supervised exercises will be performed for approximately 15 minutes. Additionally, participants in both groups will be prescribed a daily home exercise program lasting 10-15 minutes. Group B (Thoracic Plus Cervical Spine Maitland Mobilization) will receive combined thoracic and cervical spine Maitland mobilization, Thoracic mobilization will be applied to the upper thoracic segments (T1-T4) using central PA Technique. Grades III and IV mobilizations for thoracic stiffness and restore extension mobility, while lower grades will be applied in cases of increased pain sensitivity. Thoracic mobilization will be delivered for approximately 6-8 minutes, after that cervical mobilization with same protocol of supervised exercise and home pan for mechanical neck pain will be used. Each treatment session will be lasted approximately 30 minutes. Outcome measures will include: Pain intensity assessed using the Visual Analogue Scale (VAS) Functional disability will be evaluated using the Neck Disability Index (NDI), Health-related quality of life will be measured using the Short Form-36 (SF-36). The primary objective of this study is to evaluate the effects of cervical spine mobilization and thoracic spine mobilization on pain intensity, functional disability, and quality of life in patients with mechanical neck pain.",[244],"Mechanical Neck Pain",{"date":121,"type":39},{"date":41,"type":39},{"date":185,"type":21},{"name":45,"class":46},{"id":250,"slug":251,"hasResults":12,"nctId":252,"briefTitle":253,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":12,"sex":255,"minAge":18,"maxAge":114,"enrollmentInfo":256,"targetDuration":4,"studyType":22,"phases":258,"briefSummary":259,"conditions":260,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":262,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":266,"locationsCount":47},"100648349","effects-of-visual-feedback-induced-therapy-and-active-release-technique-on-shoulder-pain-lymphedema-and-functional-disability-in-post-mastectomy-patients-100648349","NCT07719725","Effects of Visual-Feedback Induced Therapy and Active Release Technique on Shoulder Pain, Lymphedema, and Functional Disability in Post-Mastectomy Patients.","Inclusion Criteria:\n\n* Female patients aged 40-65 years.\n* History of unilateral mastectomy performed at least 2 months prior.\n* Persistent shoulder pain (Numeric Pain Rating Scale 4-7).\n* Reduced shoulder range of motion or functional limitation affecting daily activities.\n* Mild to moderate lymphedema of the affected upper limb .\n\nExclusion Criteria:\n\n* History of neurological disorders affecting motor function (e.g., stroke, MS).\n* Previous shoulder surgery unrelated to mastectomy.\n* Active infection or open wounds in the affected limb.\n* Already developed frozen shoulder in diabetic patient.\n* Severe lymphedema requires intensive medical management.\n* Cognitive impairment prevents participation in therapy.","MALE",{"count":257,"type":21},44,[24],"This randomized controlled trial aims to compare the effects of visual-feedback induced therapy and Active Release Technique on shoulder pain, lymphedema, and functional disability in post-mastectomy patients. Participants will be randomly assigned to receive either conventional physiotherapy combined with Active Release Technique or conventional physiotherapy combined with visual-feedback therapy. Outcomes will be measured at baseline and after 6 weeks of intervention.",[261],"Ost-Mastectomy Shoulder Dysfunction",{"date":207,"type":39},{"date":264,"type":21},"2026-07-16",{"date":185,"type":21},{"name":45,"class":46},{"id":268,"slug":269,"hasResults":12,"nctId":270,"briefTitle":271,"officialTitle":272,"acronym":4,"eligibilityCriteria":273,"healthyVolunteers":12,"sex":16,"minAge":135,"maxAge":18,"enrollmentInfo":274,"targetDuration":4,"studyType":22,"phases":276,"briefSummary":277,"conditions":278,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":279,"startDateStruct":280,"completionDateStruct":281,"leadSponsor":282,"locationsCount":47},"100648249","effects-of-whole-body-vibration-and-pilates-on-pain-dynamic-balance-and-functional-performance-in-chronic-non-specific-low-back-pain-100648249","NCT07719699","Effects of Whole-Body Vibration and Pilates on Pain, Dynamic Balance, and Functional Performance in Chronic Non-Specific Low Back Pain","Effects of Whole-Body Vibraton and Pilates on Pain, Dynamic Balance, and Functional Performance in Chronic Non-Specific Low Back Pain","Inclusion Criteria:\n\n1. Male and Female (18-40 years age)\n2. Pain lasting for more than 12 weeks(determined by patient history)\n3. Pain scores (VAS) ranging from 3 to 8 points\n4. Pain located between T12 and gluteal folds(determined via palpation)\n5. Not having attended Pilates for low back pain for atleast 6 months prior to enrollment\n\nExclusion Criteria:\n\n1. History of spinal surgery, fractures, tumors, infections, or inflammatory spinal disease.\n2. Pregnant or lactating( strongly contraindicated for whole body vibration due to potential fetal risk and pelvic instability)\n3. Radicular pain, nerve root compression or neurological deficits.\n4. Medical comorbidities (e.g cardiovascular, neurological, endocrine or metabolic disease)(5).\n5. Physical limitations (e.g. orthopedic or rheumatic diseases, muscular injury, fibromyalgia, or pain)that could affect their ability to perform the Pilate exercises.\n6. Participants whose weight exceeds 150kg ( that's the maximum weight bearing capacity for WBV)",{"count":275,"type":21},68,[24],"Chronic non-specific low back pain (CNSLBP) affects pain, balance, and functional ability. This randomized clinical trial aims to compare the effects of whole-body vibration (WBV) and Pilates, both combined with conventional physiotherapy, on pain, dynamic balance, and functional performance.\n\nA total of 68 participants aged 18-40 years will be randomly assigned to either a WBV group or a Pilates group. Both groups will receive treatment three times per week for four weeks. Outcomes will be measured using the Visual Analog Scale (pain), Y-Balance Test (dynamic balance), and Progressive Isoinertial Lifting Evaluation (functional performance).\n\nThe results will help determine which intervention is more effective for managing CNSLBP and guide evidence-based rehabilitation practices.",[61],{"date":207,"type":39},{"date":41,"type":39},{"date":185,"type":21},{"name":45,"class":46},{"id":284,"slug":285,"hasResults":12,"nctId":286,"briefTitle":287,"officialTitle":287,"acronym":4,"eligibilityCriteria":288,"healthyVolunteers":12,"sex":16,"minAge":173,"maxAge":18,"enrollmentInfo":289,"targetDuration":4,"studyType":22,"phases":290,"briefSummary":291,"conditions":292,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":294,"startDateStruct":295,"completionDateStruct":296,"leadSponsor":297,"locationsCount":47},"100645629","effects-of-vacuum-controlled-static-versus-vacuum-controlled-dynamic-dry-cupping-on-pain-range-of-motion-and-disability-among-patients-with-chronic-low-back-pain-100645629","NCT07702617","Effects Of Vacuum Controlled Static Versus Vacuum Controlled Dynamic Dry Cupping On Pain, Range Of Motion And Disability Among Patients With Chronic Low Back Pain","Inclusion Criteria:\n\n* Age 30 to 40 years. (21)\n* Both male and female genders (15)\n* Patients experiencing LBP with a score of at least 3\u002F10 on the NPRS (22)\n* For more than three months (22).\n* Individuals whose workstations have not been ergonomically designed and who have not previously received structured ergonomic interventions related to workplace layout, task design, or load modification also involving home tasks and daily activities. (31)\n\nExclusion Criteria:\n\n* \\* Subjects with lower body condition (i.e., spondylolisthesis, spinal stenosis, osteoporosis, or intervertebral disk derangement) (15)\n\n  * Subjects with a history of cancer (15)\n  * Subjects experiencing referred leg symptoms (15)\n  * Subjects with any current local or systemic infections, vascular disease, including varicose veins (17)\n  * History of spine surgery or spinal tumor (17).",{"count":157,"type":21},[24],"This randomized controlled clinical trial aims to compare the effects of vacuum-controlled static dry cupping and vacuum-controlled dynamic dry cupping on pain intensity, lumbar range of motion, and functional disability in patients with chronic low back pain. Participants will be randomly assigned to two groups receiving either static or dynamic dry cupping along with conventional treatment. The outcomes will be assessed to determine which cupping technique is more effective in improving pain, mobility, and functional ability in individuals with chronic low back pain.\n\n\\[Time Frame: Measured at baseline (pre-intervention) and after 6 weeks (post-intervention completion).",[293],"Chronic Low-back Pain (cLBP)",{"date":207,"type":39},{"date":74,"type":21},{"date":76,"type":21},{"name":45,"class":46},{"id":299,"slug":300,"hasResults":12,"nctId":301,"briefTitle":302,"officialTitle":302,"acronym":4,"eligibilityCriteria":303,"healthyVolunteers":12,"sex":16,"minAge":135,"maxAge":18,"enrollmentInfo":304,"targetDuration":4,"studyType":22,"phases":305,"briefSummary":306,"conditions":307,"keywords":310,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":313,"startDateStruct":314,"completionDateStruct":315,"leadSponsor":316,"locationsCount":47},"100645536","effect-of-a-comprehensive-corrective-exercise-program-with-and-without-instrument-assisted-soft-tissue-mobilization-on-cervical-range-of-motion-muscle-strength-disability-and-postural-alignment-in-individuals-with-upper-crossed-syndrome-100645536","NCT07702604","Effect of a Comprehensive Corrective Exercise Program With and Without Instrument-Assisted Soft Tissue Mobilization on Cervical Range of Motion, Muscle Strength, Disability, and Postural Alignment in Individuals With Upper-Crossed Syndrome","Inclusion Criteria:\n\n* Age between 18-40 years\n* Both males and females\n* Diagnosed with Upper-Crossed Syndrome\n* Presence of forward head posture and rounded shoulders\n* Chronic neck pain related to postural dysfunction\n\nExclusion Criteria:\n\n* History of cervical spine surgery or fracture\n* Neurological conditions (e.g., radiculopathy, myelopathy)\n* Systemic musculoskeletal disorders (e.g., rheumatoid arthritis)\n* Current physiotherapy treatment for neck pain\n* Skin conditions preventing IASTM application",{"count":157,"type":21},[24],"This study is a double-blind, parallel-group randomized controlled trial designed to evaluate the effectiveness of a Comprehensive Corrective Exercise Program (CCEP) with and without Instrument-Assisted Soft Tissue Mobilization (IASTM) in individuals with Upper-Crossed Syndrome (UCS). UCS is a common postural dysfunction characterized by muscular imbalance, including tightness of the upper trapezius, levator scapulae, and pectoral muscles, along with weakness of the deep cervical flexors and scapular stabilizers. This imbalance leads to forward head posture, rounded shoulders, neck pain, reduced cervical mobility, and functional limitations, particularly in individuals exposed to prolonged sedentary activities and poor ergonomic conditions.\n\nA total of 60 participants aged 18-40 years diagnosed with Upper-Crossed Syndrome will be recruited and randomly allocated into two groups. The control group will receive a structured Comprehensive Corrective Exercise Program (CCEP), while the experimental group will receive the same exercise program combined with Instrument-Assisted Soft Tissue Mobilization (IASTM).\n\nBoth interventions will be administered three times per week for six weeks under the supervision of a trained physiotherapist. Outcome measures will be assessed at baseline and after completion of the intervention period. Primary outcomes include cervical range of motion, muscle strength assessed by the Deep Neck Flexor endurance test, functional disability measured using the Neck Disability Index, and postural alignment assessed using a plumb line method.\n\nThe aim of this study is to determine whether the addition of IASTM to a corrective exercise program results in superior improvements in cervical mobility, muscle strength, functional disability, and postural alignment compared to corrective exercise alone. It is hypothesized that the combined intervention will produce greater clinical improvements in individuals with Upper-Crossed Syndrome.",[308,309],"Upper Crossed Syndrome","Postural Dysfunction",[308,311,309,312,202],"Neck Pain","Corrective Exercises",{"date":207,"type":39},{"date":264,"type":21},{"date":76,"type":21},{"name":45,"class":46},{"id":318,"slug":319,"hasResults":12,"nctId":320,"briefTitle":321,"officialTitle":321,"acronym":4,"eligibilityCriteria":322,"healthyVolunteers":12,"sex":16,"minAge":323,"maxAge":84,"enrollmentInfo":324,"targetDuration":4,"studyType":22,"phases":325,"briefSummary":326,"conditions":327,"keywords":329,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":334,"lastUpdatePostDateStruct":335,"startDateStruct":337,"completionDateStruct":338,"leadSponsor":340,"locationsCount":47},"100645756","effects-of-foot-core-strengthening-and-sensorimotor-re-training-with-routine-physical-therapy-on-pain-function-and-plantar-pressure-in-patients-with-plantar-fasciitis-100645756","NCT07703111","Effects of Foot-Core Strengthening and Sensorimotor Re-training With Routine Physical Therapy on Pain, Function, and Plantar Pressure in Patients With Plantar Fasciitis.","Inclusion Criteria:\n\nAge 35-60 Years Sharp and worsen pain with the first few steps out of bed in morning. Clinical diagnosis of plantar fasciitis of at least three months duration -\n\nExclusion Criteria:\n\nHistory of ankle and foot surgery Diagnosis for Peripheral neuropathy, Tarsal tunnel syndrome Corticosteroid injection into heel within the last three months. Diagnosed neurological and rheumatological disease calcaneal fractures Pregnant Women-","35 Years",{"count":116,"type":21},[24],"This study aims to compare the effects of foot core strengthening and sensorimotor re-training, each combined with routine physical therapy, on pain, functional ability, and plantar pressure in patients with Plantar Fasciitis.\n\nParticipants will be divided into two groups: one receiving foot core strengthening with routine physical therapy and the other receiving sensorimotor re-training with routine physical therapy. The study will evaluate which intervention is more effective in reducing pain, improving function, and normalizing plantar pressure distribution.",[328],"Plantar Fasciitis",[328,330,331,332,333],"Foot Core Strengthening","Sensorimotor Training","Plantar Pressure","Foot Function","2026-07-09",{"date":336,"type":39},"2026-07-14",{"date":123,"type":21},{"date":339,"type":21},"2026-11-20",{"name":45,"class":46},{"id":342,"slug":343,"hasResults":12,"nctId":344,"briefTitle":345,"officialTitle":345,"acronym":4,"eligibilityCriteria":346,"healthyVolunteers":12,"sex":16,"minAge":239,"maxAge":347,"enrollmentInfo":348,"targetDuration":4,"studyType":22,"phases":349,"briefSummary":350,"conditions":351,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":334,"lastUpdatePostDateStruct":353,"startDateStruct":354,"completionDateStruct":355,"leadSponsor":356,"locationsCount":47},"100645524","effect-of-rocabado-exercises-with-strain-counter-strain-technique-on-muscles-of-mastication-for-pain-jaw-function-and-quality-of-life-in-patients-with-temporomandibular-joint-dysfunction-100645524","NCT07703059","Effect of Rocabado Exercises With Strain Counter-Strain Technique on Muscles of Mastication for Pain, Jaw Function, and Quality of Life in Patients With Temporomandibular Joint Dysfunction","Inclusion Criteria:\n\n* Diagnosed patient of muscular TMJ ;According to Fonseca Questionnaire, ranging in the age group of 20 to 50 years, with both male and female were included in the study; Maximum mouth opening (MMO) 40-60mm for diagnosis of muscular TMJ ; Mild to moderate TMJ pain ; Unilateral TMJ ; Diagnostic features of muscular TMJ dysfunction: Pain location: Jaw, temple and masseter region ; Pain Behavior: Increase with chewing, talking and clenching ; Palpation findings: tenderness at masseter and temporal region ; ROM findings: limited and painful mouth opening (\\\u003C40mm) when measured with maximum mouth opening test ; MMO Test: The test involves measuring the maximum distance between the incisal edges of the upper and lower central incisors when the mouth is opened as wide as possible. This measurement is typically performed using a calibrated ruler, Vernier calipers, or a fiber ruler, with the subject positioned upright and instructed to open their mouth maximally.\n\nExclusion Criteria:\n\n* Who do not fall into the mentioned age group, with severe TMJ dysfunction according to Fonseca Questionnaire ; Recent oral surgeries; Spondyloarthropathies ;Recent oral trauma ; Systemic disease(hypothyroidism, hypercalcemia) ; Pregnant females ;Metal implants in the oral cavity ; Patient on TMJ drugs use ; Lactating females ; Neurological deficit (MS, Parkinson diseases) that effects the fascial muscles ; Any other inflammatory diseases","50 Years",{"count":257,"type":21},[24],"Temporomandibular joint dysfunction (TMD) is a common musculoskeletal disorder affecting the jaw joint and masticatory muscles, leading to pain, limited jaw function, and reduced quality of life. Conservative management includes therapeutic exercises and manual therapy. Rocabado exercises improve jaw mechanics and posture, while the Strain Counterstrain technique reduces muscle tenderness and pain.\n\nThis randomized controlled trial aims to evaluate the effectiveness of Rocabado exercises alone versus Rocabado exercises combined with the Strain Counterstrain technique in patients with muscular TMD. The intervention will be conducted over six weeks, with outcomes measured for pain, jaw function, and quality of life. The study seeks to determine whether the combined approach provides superior clinical outcomes.",[352],"Temporal Mandibular Joint Dysfunction",{"date":336,"type":39},{"date":74,"type":21},{"date":339,"type":21},{"name":45,"class":46},{"id":358,"slug":359,"hasResults":12,"nctId":360,"briefTitle":361,"officialTitle":361,"acronym":4,"eligibilityCriteria":362,"healthyVolunteers":12,"sex":134,"minAge":135,"maxAge":155,"enrollmentInfo":363,"targetDuration":4,"studyType":22,"phases":365,"briefSummary":366,"conditions":367,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":334,"lastUpdatePostDateStruct":369,"startDateStruct":370,"completionDateStruct":372,"leadSponsor":374,"locationsCount":47},"100645470","effect-of-short-foot-exercise-combined-with-focused-hip-and-knee-exercises-on-pain-q-angle-and-functional-outcomes-in-female-patients-with-patellofemoral-pain-syndrome-100645470","NCT07703072","Effect of Short Foot Exercise Combined With Focused Hip and Knee Exercises on Pain, Q Angle and Functional Outcomes in Female Patients With Patellofemoral Pain Syndrome","Inclusion Criteria:\n\nDiagnosed cases of patellofemoral pain syndrome confirmed by this protocol.\n\n1. Females aged 18-45 years\n2. Anterior or retro patellar knee pain lasting ≥ 6 weeks\n3. Pain provoked by at least one PFJ-loading task, including:\n\n   1. squatting,\n   2. stair climbing\u002Fdescending,\n   3. running,\n   4. prolonged sitting with knees flexed\n4. Pain elicited by at least two of four clinical tests;\n\n   1. Pain during isometric quadriceps contraction at 20-30° knee flexion\n   2. Pain on palpation of the patellofemoral joint line\n   3. Pain during patellar compression\n   4. Pain during active resisted knee extension\n\nExclusion Criteria:\n\nHistory of patellar instability, including subluxation or dislocation 2. Evidence of tibiofemoral pathology, such as: Ligamentous injuries, meniscal tears, and symptomatic knee effusion.\n\n3\\. Previous knee surgery within the last 12 months 4. Radiographic or clinical knee osteoarthritis. 5. Neurological disorders or systemic inflammatory diseases that may influence gait or pain perception.\n\n\\-",{"count":364,"type":21},38,[24],"This randomized controlled trial aims to evaluate the effectiveness of short foot exercises combined with focused hip and knee strengthening on pain, Q-angle, and functional outcomes in female patients with patellofemoral pain syndrome (PFPS). Thirty-eight participants aged 18-45 years will be randomly assigned to either an experimental group (short foot + hip and knee exercises) or a control group (hip and knee exercises only) for a 6-week supervised rehabilitation program.",[368],"Patellofemoral Pain Syndrome",{"date":336,"type":39},{"date":371,"type":21},"2026-07-18",{"date":373,"type":21},"2026-11-15",{"name":45,"class":46},{"id":376,"slug":377,"hasResults":12,"nctId":378,"briefTitle":379,"officialTitle":379,"acronym":4,"eligibilityCriteria":380,"healthyVolunteers":12,"sex":16,"minAge":155,"maxAge":381,"enrollmentInfo":382,"targetDuration":4,"studyType":22,"phases":383,"briefSummary":384,"conditions":385,"keywords":387,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":392,"lastUpdatePostDateStruct":393,"startDateStruct":394,"completionDateStruct":395,"leadSponsor":396,"locationsCount":47},"100645161","effects-of-clinical-based-versus-synchronized-telerehabilitation-on-pain-exercise-adherence-and-functional-disability-among-patients-with-grade-ii-cervical-spondylosis-100645161","NCT07679373","Effects of Clinical Based Versus Synchronized Telerehabilitation on Pain, Exercise Adherence, and Functional Disability Among Patients With Grade-II Cervical Spondylosis.","Inclusion Criteria:\n\n* Middle age adults (45-64) years\n* Both gender ( male and female )\n* Clinical daignosis of cervical spondylosis grade 2\n* Mild to moderate pain on NPRS\n* Sub acute stage ( 2-6 weeks) of grade 2 cervical spondylosis\n* Able to follow instructions and give informed consent (cognitively able) Neurologically stable\n\nExclusion Criteria:\n\n* Prior cervical spine surgery within the last 1 months or cervical instability.\n* Inflammtory or systemic rheumatologic disease affecting the cervical spine (e.g., active rheumatoid arthritis ) or infection, tumor, fracture.\n* Severe cardiopulmonary or other medical comorbidity that contraindicates exercise (unstable angina, uncontriolled hypertension, recent MI)\n* Severe hearing or visual impairment\n* No smoking and daibetic history","64 Years",{"count":116,"type":21},[24],"This randomized controlled trial aims to compare the effects of clinical-based rehabilitation and synchronized telerehabilitation on pain, exercise adherence, and functional disability in patients with Grade-II cervical spondylosis. A total of 52 participants will be randomly allocated into two parallel groups. Both groups will receive a standardized 6-week rehabilitation program, including cervical mobility exercises, strengthening, isometric exercises, stretching, and Mulligan self-mobilization techniques. The clinical group will receive in-person physiotherapy, while the telerehabilitation group will undergo real-time supervised sessions via video conferencing. Outcome measures will include pain (Numeric Pain Rating Scale), functional disability (Neck Disability Index), and exercise adherence (Exercise Adherence Rating Scale), assessed at baseline and post-intervention. The study aims to determine whether synchronized telerehabilitation is as effective as clinical-based rehabilitation and may provide a more accessible alternative for delivering physiotherapy care.",[386],"Grade-II Cervical Spondylosis",[388,62,389,390,391],"Telerehabilitation","Excercise Adherence","Functional Disability","Cervical Spondylosis","2026-06-25",{"date":74,"type":39},{"date":74,"type":21},{"date":76,"type":21},{"name":45,"class":46},{"id":398,"slug":399,"hasResults":12,"nctId":400,"briefTitle":401,"officialTitle":401,"acronym":4,"eligibilityCriteria":402,"healthyVolunteers":12,"sex":16,"minAge":135,"maxAge":18,"enrollmentInfo":403,"targetDuration":4,"studyType":22,"phases":405,"briefSummary":406,"conditions":407,"keywords":409,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":392,"lastUpdatePostDateStruct":412,"startDateStruct":413,"completionDateStruct":415,"leadSponsor":416,"locationsCount":47},"100643666","effects-of-telerehabilitation-and-supervised-clinic-based-rehab-with-pain-neuroscience-education-for-painkinesiophobia-and-functional-disability-among-chronic-non-specific-neck-pain-patients-100643666","NCT07617623","Effects of Telerehabilitation and Supervised Clinic Based Rehab With Pain Neuroscience Education for Pain,Kinesiophobia and Functional Disability Among Chronic Non-Specific Neck Pain Patients","Inclusion Criteria:\n\n1. Age between 18-40 years of both male and female gender.\n2. Currently suffering from neck pain \\& bilateral neck pain for at least three months.\n3. Moderate pain intensity (30mm to 70mm) on Visual Analogue Scale .\n4. Access \\& knowledge of mobile phone and internet use .\n\nExclusion Criteria:\n\n1. Any previous neck surgery or cervical trauma .\n2. Fibromyalgia \\& Myelopathy .\n3. Spinal deformities like thoracic hyper kyphosis or scoliosis .\n4. Cervical radiculopathy ,vertigo, cancer \\& vertebral fractures.\n5. Infection or inflammatory arthritis in cervical spine .\n6. History of the whiplash injury .\n7. Physiotherapeutic treatment in the last six months .\n8. Cognitive disorder that prohibited the pain neuroscience education intervention from being followed .",{"count":404,"type":21},45,[24],"Chronic non-specific neck pain is a common musculoskeletal condition affecting a large proportion of the population worldwide. It is characterized by persistent neck pain lasting more than three months without a specific underlying pathology. Many patients experience ongoing symptoms such as pain, reduced range of motion, functional limitations, and psychological factors like kinesiophobia, which can negatively affect recovery and quality of life.\n\nConventional physiotherapy, including supervised clinic-based rehabilitation, is widely used for the management of chronic non-specific neck pain. These programs typically involve exercise therapy and patient education; however, access to regular in-clinic treatment can be limited due to factors such as travel, cost, and time constraints.\n\nTelerehabilitation has emerged as an alternative approach that allows delivery of physiotherapy services through online platforms, improving accessibility and convenience for patients. In addition, pain neuroscience education (PNE) is an evidence-based strategy that helps patients understand pain mechanisms, reduce fear-avoidance behaviors, and improve treatment outcomes when combined with exercise therapy.\n\nAlthough both telerehabilitation and supervised clinic-based rehabilitation are effective, there is limited evidence directly comparing these two approaches when combined with standardized pain neuroscience education.\n\nTherefore, this randomized controlled trial aims to compare the effects of telerehabilitation with pain neuroscience education and supervised clinic-based rehabilitation with pain neuroscience education on pain intensity, functional disability, and kinesiophobia in individuals with chronic non-specific neck pain.",[408],"Chronic Non-Specific Neck Pain",[410,388,411,205,408],"Pain Neuroscience Education","Supervised Clinic Based Rehab",{"date":183,"type":39},{"date":414,"type":21},"2026-06",{"date":339,"type":21},{"name":45,"class":46},{"id":418,"slug":419,"hasResults":12,"nctId":420,"briefTitle":421,"officialTitle":422,"acronym":4,"eligibilityCriteria":423,"healthyVolunteers":12,"sex":16,"minAge":347,"maxAge":114,"enrollmentInfo":424,"targetDuration":4,"studyType":22,"phases":426,"briefSummary":427,"conditions":428,"keywords":430,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":433,"lastUpdatePostDateStruct":434,"startDateStruct":436,"completionDateStruct":438,"leadSponsor":439,"locationsCount":106},"100644434","effects-of-tai-chi-therapy-versus-qi-gong-in-stage-i-parkinsons-patients-100644434","NCT07662837","Effects of Tai Chi Therapy Versus Qi-Gong in Stage-I Parkinson's Patients.","Effects of Tai Chi Therapy Versus Qi-Gong on Postural Control, Functional Balance , and Motor Function in Stage-I Parkinson's Patients.","Inclusion Criteria:\n\nDiagnosis of PD based on the Hoehn \\& Yahr staging system (Stages I). Male or female patients aged between 50-65 years. Currently receiving stable anti-Parkinsonian medication, with no changes in the treatment regimen for at least 3 months. Basic self-care ability with no severe cognitive impairment (Mini-Mental State Examination \\[MMSE\\] score ≥24).\n\nExclusion Criteria:\n\nDepression, as assessed based on a score of \\>16 for the Beck Depression Inventory-II (BDI-II). Recent deep brain stimulation (DBS) treatment. Use of medication that interferes with cognition, alertness, or attention. Current participation in an exercise training program.",{"count":425,"type":21},50,[24],"This study has important clinical, academic, and practical relevance in neuromuscular rehabilitation. Clinically, it aims to identify effective and tolerable rehabilitation strategies for individuals with Parkinson's disease by comparing Tai Chi Therapy with Qi-Gong there by supporting evidence-based physiotherapy practice and improving patient adherence. Academically, it contributes to the limited literature on comparative effectiveness of these interventions and incorporates patient-centered outcomes such as exercise perception, which are often underreported. From a practical and societal perspective, identifying a more acceptable and effective approach may enhance long-term participation in rehabilitation, potentially slow disease progression, and reduce the overall healthcare burden associated with Parkinson's disease.",[429],"PARKINSON DISEASE (Disorder)",[431,432],"Tai Chi","Qi-Gong","2026-06-17",{"date":435,"type":39},"2026-06-23",{"date":437,"type":39},"2026-05-30",{"date":231,"type":21},{"name":45,"class":46},{"id":441,"slug":442,"hasResults":12,"nctId":443,"briefTitle":444,"officialTitle":444,"acronym":4,"eligibilityCriteria":445,"healthyVolunteers":12,"sex":16,"minAge":155,"maxAge":114,"enrollmentInfo":446,"targetDuration":4,"studyType":22,"phases":448,"briefSummary":449,"conditions":450,"keywords":452,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":433,"lastUpdatePostDateStruct":458,"startDateStruct":460,"completionDateStruct":462,"leadSponsor":463,"locationsCount":106},"100614695","combined-effects-of-soft-robotic-hand-and-electrical-stimulation-on-hand-function-in-stroke-survivors-100614695","NCT07282938","Combined Effects of Soft Robotic Hand and Electrical Stimulation on Hand Function in Stroke Survivors","Inclusion Criteria:\n\n* Diagnosed with their first episode of stroke.\n* Participants with 3-6 months post stroke.\n* Participants with normal cognition on Montreal Cognitive Assessment (MOCA) ≥24.\n* Participants with the ability to extend Metacarpophalangeal (MCP) and Proximal Interphalangeal (PIP) joint to 180 degree passively\n* Modified Ashworth Scale \\\u003C 2.\n* Participants with the score of 10 to 16 on National Institute of Health Stroke Scale Score (NIHSS Score).\n\nExclusion Criteria:\n\n* Presence of other neurological, neuromuscular, orthopedic diseases, or\n* conditions that may interfere with task performance.\n* Participants with sensory disturbances in the fingers",{"count":447,"type":21},64,[24],"Stroke is a clinically delineated syndrome, which is characterised by an acute, focal neurological deficit resulting from vascular injury (infarction or haemorrhage) within the central nervous system. Notably, around 80 percent of stroke survivors experience post-stroke deficits in upper extremity (UE) motor performance, impacting grip strength, dexterity, and functional independence, which greatly hinder the ability of stroke patients to carry out activities of daily living (ADL), and in turn affects their overall quality of life (QOL).One potential solution to these difficulties is the creation of rehabilitation robotic devices that incorporate hand technology and electrical stimulation. Although soft robotic assistive devices and electrical stimulation have each shown positive effects on motor recovery, their combined use has yet to be thoroughly investigated. This study intends to determine if the simultaneous application of these therapies can speed up rehabilitation results in comparison to independent therapies. Stroke Participants will be divided into two groups, Experimental group and Control group. Both the groups will receive intervention for 40 min\u002Fday, 03 days\u002Fweek, for 08 week and measurements will be taken prior to the treatment, after 4 weeks of treatment and 8 weeks post-treatment.",[90,451],"Cerebro-vascular Accident",[90,453,454,455,456,457],"hand impairments","soft robotic hand","electrical stimulation","robotic therapy","Cerebrovascular accident",{"date":459,"type":39},"2026-06-18",{"date":461,"type":39},"2025-12-08",{"date":414,"type":21},{"name":45,"class":46},{"id":465,"slug":466,"hasResults":12,"nctId":467,"briefTitle":468,"officialTitle":469,"acronym":4,"eligibilityCriteria":470,"healthyVolunteers":12,"sex":16,"minAge":155,"maxAge":471,"enrollmentInfo":472,"targetDuration":4,"studyType":22,"phases":474,"briefSummary":475,"conditions":476,"keywords":478,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":433,"lastUpdatePostDateStruct":482,"startDateStruct":483,"completionDateStruct":485,"leadSponsor":487,"locationsCount":47},"100612460","comperative-effects-of-transcutaneous-auricular-and-cervical-vagus-nerve-stimulation-in-subacute-stroke-patients-100612460","NCT07253870","Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients","Comparative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation on Upper Limb Function, Cognition and Quality of Life in Subacute Stroke Patients","Inclusion Criteria:\n\n* First ever ischemic stroke\n* Subacute phase of stroke 3-6 months post onset\n* Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores ranged from 20 - 50\n\nExclusion Criteria:\n\n* Previous injury or surgical intervention of vagus nerve\n* Patients with cardiac arrest and arrythmias\n* Uncontrolled hypertension\n* Apraxia\n* Other neurologic or musculoskeletal diseases\n* Presence of implanted electronic devices","70 Years",{"count":473,"type":21},54,[24],"This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.",[90,477],"Stroke, Acute",[479,480,481],"Task Specific Training","Upper Limb Function","Cognition",{"date":459,"type":39},{"date":484,"type":39},"2025-11-20",{"date":486,"type":21},"2026-06-20",{"name":45,"class":46},{"id":489,"slug":490,"hasResults":12,"nctId":491,"briefTitle":492,"officialTitle":493,"acronym":494,"eligibilityCriteria":495,"healthyVolunteers":12,"sex":16,"minAge":496,"maxAge":497,"enrollmentInfo":498,"targetDuration":4,"studyType":22,"phases":500,"briefSummary":501,"conditions":502,"keywords":505,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":433,"lastUpdatePostDateStruct":509,"startDateStruct":510,"completionDateStruct":512,"leadSponsor":513,"locationsCount":47},"100612459","effects-of-hand-and-arm-bimanual-intensive-therapy-including-lower-extremity-in-spastic-cerebral-palsy-100612459","NCT07253857","Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity in Spastic Cerebral Palsy","Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity on Motor Function and Cognition in Children With Spastic Cerebral Palsy","HABIT-ILE","Inclusion Criteria:\n\n* Diagnosed with diplegic cerebral palsy\n* CP children with manual ability level 1-3 on manual ability classification system\n* Participants with gross motor function classification system level ranging from 1-3 will be included in the study.\n* With an ability to grasp light objects and lift the more affected arm 15 cm above a table surface.\n* Base line cognition level should be 20 or above assessed through mini mental state exam for children (MMC).\n\nExclusion Criteria:\n\n* Uncontrolled seizures\n* Recent or planned botulinum toxin injections within 6 months\n* Any recent orthopedic interventions that may affect motor function\n* Visual impairments impeding with treatment protocol","6 Years","12 Years",{"count":499,"type":21},42,[24],"Cerebral palsy (CP), particularly the spastic diplegic subtype, is characterized by motor impairments such as spasticity and mobility limitations. In addition to motor dysfunction, children with CP often experience cognitive impairments affecting decision-making, problem-solving, working memory, selective attention, and inhibitory control. These non-motor challenges contribute to reduced social interaction and quality of life.\n\nHand-Arm Bimanual Intensive Therapy Including Lower Extremity (HABIT-ILE) has demonstrated improvements in gross motor function among children with spastic CP. However, evidence regarding its impact on cognitive outcomes remains limited. This randomized controlled trial (RCT) aims to evaluate the effects of HABIT-ILE compared with conventional therapy on both motor and cognitive functions in children with spastic diplegic CP. By addressing both upper and lower limb the research seeks to provide a comprehensive therapeutic approach that may yield more significant developmental benefits. Ultimately, the findings could inform the interventions for improving outcomes in pediatric populations affected by diplegic cerebral palsy.\n\nParticipants will receive 90 hours of intervention, with assessments conducted at baseline, mid-intervention, and post-intervention. The study will investigate outcomes across motor domains and cognitive functions such as inhibitory control and working memory. Findings are expected to inform comprehensive therapeutic approaches to improve developmental outcomes and quality of life in pediatric populations affected by spastic diplegic CP.",[503,504],"Cerebral Palsy","Cerebral Palsy, Spastic",[494,506,503,507,508],"Intensive motor therapy","diplegic cerebral palsy with spasticity","Spastic cerebral palsy",{"date":459,"type":39},{"date":511,"type":39},"2025-12-20",{"date":414,"type":21},{"name":45,"class":46},{"id":515,"slug":516,"hasResults":12,"nctId":517,"briefTitle":518,"officialTitle":519,"acronym":520,"eligibilityCriteria":521,"healthyVolunteers":12,"sex":16,"minAge":522,"maxAge":523,"enrollmentInfo":524,"targetDuration":4,"studyType":22,"phases":526,"briefSummary":527,"conditions":528,"keywords":531,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":539,"lastUpdatePostDateStruct":540,"startDateStruct":541,"completionDateStruct":542,"leadSponsor":543,"locationsCount":106},"100641120","effects-of-core-stabilization-exercises-and-rotation-angular-breathing-exercises-among-idiopathic-scoliosis-patients-100641120","NCT07601893","Effects of Core Stabilization Exercises and Rotation Angular Breathing Exercises Among Idiopathic Scoliosis Patients","Effects of Core Stabilization Exercises and Rotational Angular Breathing Exercises on Cobb's Angle, Trunk Rotation, Inspiratory Capacity and Spinal Appearance Among Idopathic Scoliosis Patients","CSE RAB IS","Inclusion Criteria:\n\n* Adolescents aged 10-17 years\n* Both male and female participants\n* Diagnosed cases of idiopathic scoliosis\n* Cobb's angle between 10° and 25°\n* Both thoracic and lumbar spine scoliosis patients\n* Both C-shaped or S-shaped curve scoliosis patients\n\nExclusion Criteria:\n\n* Previous spinal surgery\n* Significant neuromuscular disorders (e.g, muscular dystrophy, cerebral palsy)\n* Other medical conditions affecting participation (e.g, respiratory or cardiac)\n* Any contraindication to exercise program","10 Years","17 Years",{"count":525,"type":21},32,[24],"This study is a single-blind, two-arm parallel-group randomized controlled trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on adolescents with idiopathic scoliosis. Participants aged 10-18 years with a Cobb angle between 10° and 25° will be randomly assigned to either an experimental group receiving a structured exercise program or a control group receiving standard care.\n\nThe intervention will be conducted over 12 weeks, with outcomes assessed at baseline, post-intervention, and follow-up periods. Primary outcomes include Cobb angle, angle of trunk rotation, inspiratory capacity, and spinal appearance. The study aims to determine whether the combined exercise approach is more effective than standard care in improving spinal alignment, respiratory function, and physical appearance.",[529,530],"Idiopathic Adolescent Scoliosis","Scoliosis Idiopathic",[532,533,534,535,536,537,538],"Core stabilization exercises","Rotational Angular Breathing Exercises","Cobb's angle","Inspiratory capacity","Idiopathic scoliosis","Spinal Appearance","Trunk rotation","2026-06-16",{"date":459,"type":39},{"date":459,"type":21},{"date":373,"type":21},{"name":45,"class":46},{"id":545,"slug":546,"hasResults":12,"nctId":547,"briefTitle":548,"officialTitle":548,"acronym":549,"eligibilityCriteria":550,"healthyVolunteers":12,"sex":134,"minAge":135,"maxAge":323,"enrollmentInfo":551,"targetDuration":4,"studyType":22,"phases":553,"briefSummary":554,"conditions":555,"keywords":562,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":539,"lastUpdatePostDateStruct":565,"startDateStruct":566,"completionDateStruct":568,"leadSponsor":569,"locationsCount":47},"100635561","effects-of-leg-ergometer-versus-arm-ergometer-on-blood-glucose-exercise-tolerance-weight-and-psychological-stress-among-gestational-diabetic-patients-100635561","NCT07554287","Effects of Leg Ergometer Versus Arm Ergometer on Blood Glucose, Exercise Tolerance, Weight, and Psychological Stress Among Gestational Diabetic Patients","GDM","Inclusion Criteria:\n\n1. Female participants aged 18-35 years.\n2. Gestational age 14-28 weeks (second trimester).\n3. Singleton pregnancy (confirmed by obstetric record) only to avoid complications of multiple gestation.\n4. Include both primigravida and multigravida (i.e., first or subsequent pregnancy).\n5. Women with first time GDM in pregnancy.\n6. Women with clinical diagnosis of gestational diabetes according to hospital\u002FWHO criteria or hospital diagnostic test.\n7. Blood glucose levels:\n\n   Random capillary glucose \\\u003C 200 mg\u002FdL at screening (to exclude overt diabetes)\n8. Blood pressure:\n\n   * Systolic BP \\\u003C 140 mmHg and Diastolic BP \\\u003C 90 mmHg (no confirmed gestational hypertension).\n   * If BP ≥140\u002F90 mmHg, confirm with repeat measurement 4 hours apart; exclude if persistent.\n9. Willingness to participate and provide written informed consent.\n10. Medically cleared by obstetrician to participate in moderate aerobic exercise.\n\nExclusion Criteria:\n\n1. Previous Cesarean section or medically indicated bed rest.\n2. Known pre-existing diabetes mellitus (Type 1 or Type 2 prior to pregnancy).\n3. Known major obstetric complications (e.g., placenta previa, severe pre- eclampsia).\n4. Patients having multiple\u002Ftwin\u002Ftriplet pregnancies.\n5. Known major fetal anomaly.\n6. Anemic women with Hb \\\u003C 9 g\u002FdL (excluded to prevent exercise intolerance).\n7. Uncontrolled cardiovascular disease, musculoskeletal, or medical contraindications to exercise.\n8. Psychiatric conditions severe enough to hinder informed consent.\n9. Any other medical condition that, in the opinion of the obstetrician, makes participation unsafe.",{"count":552,"type":21},108,[24],"The current study is a single-blind, parallel-group randomized controlled trial involving 108 participants with diabetes during pregnancy. The trial will compare leg ergometer with arm ergometer. Interventions will be delivered three times per week for eight weeks. The primary outcomes are glucose, exercise tolerance, weight, and psychological stress. Assessments will be conducted at baseline and after eight weeks. The trial will be carried out at Jinnah hospital, Services hospital, Sir Ganga Ram Hospital, Lahore. The hypothesis is that the leg ergometer including aerobic exercise will result in greater reduction in glucose and exercise tolerance, weight and stress management than arm ergometer.",[556,557,558,559,560,561],"Diabetes During Pregnancy","Pregnancy Complications","Pregnancy in Diabetes","Gestational Diabetes Mellitus (GDM)","Diabetes Complication","Gestational",[563,564,549,561],"gestational diabetes","diabetes in pregnancy",{"date":459,"type":39},{"date":567,"type":39},"2026-05-26",{"date":43,"type":21},{"name":45,"class":46},""]