[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lanzhou University Second Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":95},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,39,64],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":5},"100651380","effect-of-intrauterine-insemination-on-subsequent-pregnancy-outcomes-in-couples-with-unexplained-pregnancy-loss-a-multicenter-open-label-randomized-controlled-trial-100651380",false,"NCT07759609","Effect of Intrauterine Insemination on Subsequent Pregnancy Outcomes in Couples With Unexplained Pregnancy Loss: A Multicenter, Open-label, Randomized Controlled Trial","Inclusion Criteria:\n\n* Female participants aged 20-37 years.\n* History of at least one ultrasound-confirmed pregnancy loss (excluding biochemical pregnancy, ectopic pregnancy, and hydatidiform mole), with the most recent pregnancy loss occurring within the previous 12 months.\n* Desire for pregnancy at the time of enrollment.\n* Basal follicle-stimulating hormone (FSH) \\\u003C10 IU\u002FL.\n* Anti-Müllerian hormone (AMH) \\>1.1 ng\u002FmL.\n* Male partner's semen analysis meeting the criteria for intrauterine insemination (IUI), with a post-processing total progressive motile sperm count ≥5 × 10⁶.\n* Ability and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n* Congenital or acquired uterine structural abnormalities.\n* Thyroid dysfunction, defined as thyroid-stimulating hormone (TSH) \\>4.0 mIU\u002FL.\n* Positive antiphospholipid antibodies, including lupus anticoagulant, anticardiolipin antibodies, or anti-β2 glycoprotein I antibodies.\n* Parental chromosomal abnormalities or a history of fetal chromosomal abnormalities in a previous pregnancy.\n* Participation in another interventional clinical trial during the study period.","FEMALE","20 Years","37 Years",{"count":19,"type":20},558,"ESTIMATED","INTERVENTIONAL",[23],"NA","Unexplained pregnancy loss remains a major reproductive challenge, and effective management strategies for affected couples are limited. Although intrauterine insemination (IUI) is widely used in reproductive medicine, its effectiveness in improving subsequent pregnancy outcomes among couples with unexplained pregnancy loss has not been well established.\n\nThis multicenter, open-label, randomized controlled trial aims to evaluate whether IUI improves subsequent pregnancy outcomes compared with natural conception in couples with unexplained pregnancy loss. A total of 558 eligible couples will be enrolled and randomly assigned to either an IUI group or a natural conception group. Participants will be followed to assess reproductive outcomes. The findings of this study are expected to provide high-quality evidence regarding the role of IUI in the management of unexplained pregnancy loss and to inform future clinical practice.",[26],"Unexplained Pregnancy Loss","RECRUITING","2026-08-06",{"date":30,"type":31},"2026-08-12","ACTUAL",{"date":33,"type":31},"2026-01-27",{"date":35,"type":20},"2027-12-31",{"name":37,"class":38},"Lanzhou University Second Hospital","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":46,"minAge":47,"maxAge":4,"enrollmentInfo":48,"targetDuration":50,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},"100630782","effect-of-negative-pressure-suction-on-fluid-absorption-and-infection-in-flexible-ureteroscopy-100630782","NCT07492147","Effect of Negative Pressure Suction on Fluid Absorption and Infection in Flexible Ureteroscopy","Impact of Negative Pressure Suction on Irrigation Fluid Absorption and Postoperative Infection Risk During Flexible Ureteroscopic Lithotripsy: A Prospective Cohort Study","Inclusion Criteria:\n\n* Patients aged 18 years and older with kidney stones who meet the surgical indications for RIRS;\n* Patients who have provided informed consent.\n\nExclusion Criteria:\n\n* Concurrent combination with other surgical procedures, such as percutaneous nephrolithotomy (PCNL);\n* Patients with malignancies, urinary tuberculosis, immune system diseases, or hyperthyroidism;\n* Congenital renal anomalies, such as polycystic kidney disease or horseshoe kidney;\n* Presence of untreated urinary tract infections;\n* Inability to tolerate surgery due to severe cardiopulmonary dysfunction, hepatic or renal insufficiency, or coagulation abnormalities.","ALL","18 Years",{"count":49,"type":20},400,"7 Days","OBSERVATIONAL","The goal of this observational study is to learn about the effects of using negative pressure suction during retrograde intrarenal surgery (RIRS) in patients aged 18 and older with kidney stones. The main questions it aims to answer are:\n\n1. Does using negative pressure suction during surgery affect the amount of irrigation fluid absorbed by the patient's body?\n2. Does using negative pressure suction reduce the risk of postoperative infections, such as fever, systemic inflammatory response syndrome (SIRS), and urosepsis? Researchers will compare patients who undergo surgery with a negative pressure suction sheath to patients who undergo surgery with a standard sheath (without suction) to see if the suction technology reduces fluid absorption and lowers the risk of postoperative complications.\n\nParticipants will undergo their scheduled kidney stone surgery as part of their regular medical care. Researchers will collect their routine clinical data from the hospital system, including:\n\n1. Preoperative test results (such as CT scans, ultrasounds, and urine tests).\n2. Intraoperative data (such as surgery duration and the exact amount of fluid absorbed, measured by a monitoring device).\n3. Postoperative recovery data (such as body temperature, pain levels, hospital stay length, and any signs of infection).",[54],"Kidney Stones","2026-03-19",{"date":57,"type":31},"2026-03-25",{"date":59,"type":31},"2026-03-09",{"date":61,"type":20},"2027-07-07",{"name":37,"class":38},1,{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":46,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":4,"studyType":21,"phases":76,"briefSummary":77,"conditions":78,"keywords":82,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":63},"100597476","effects-of-enhanced-external-counterpulsation-combined-with-cardiac-rehabilitation-in-patients-with-atrial-fibrillation-100597476","NCT07058987","Effects of Enhanced External Counterpulsation Combined With Cardiac Rehabilitation in Patients With Atrial Fibrillation","A Prospective Randomized Controlled Study on the Effects of Enhanced External Counterpulsation Combined With Cardiac Rehabilitation on Cardiac Function and Exercise Capacity in Patients With Atrial Fibrillation","EECP AF CR","Inclusion Criteria:\n\n* Age between 40 and 80 years\n* Diagnosed with persistent or paroxysmal atrial fibrillation, confirmed by ECG or Holter\n* Stable medical condition and able to participate in cardiac rehabilitation and EECP therapy\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Recent acute myocardial infarction, unstable angina, or decompensated heart failure within the past 4 weeks\n* Severe valvular heart disease or left ventricular ejection fraction \\\u003C30%\n* Severe peripheral vascular disease or deep vein thrombosis\n* Severe pulmonary disease or active infection\n* History of bleeding disorders or contraindications to EECP\n* Cognitive impairment or psychiatric condition affecting study participation\n* Participation in another clinical trial within the past 3 months","40 Years","80 Years",{"count":75,"type":20},200,[23],"This is a prospective randomized controlled trial designed to evaluate the effectiveness of enhanced external counterpulsation (EECP) combined with cardiac rehabilitation in patients with atrial fibrillation. The study aims to assess whether this combined intervention can improve cardiac function and exercise capacity compared to standard care alone. Eligible participants will be randomly assigned to receive either the EECP plus cardiac rehabilitation program or routine treatment. Primary outcomes include changes in left ventricular ejection fraction (LVEF) and six-minute walking distance (6MWD). The study will be conducted at Lanzhou University Second Hospital.",[79,80,81],"Atrial Fibrillation (AF)","Heart Failure (HF)","Cardiac Rehabilitation",[83,81,84,85],"Atrial Fibrillation","Enhanced External Counterpulsation","Exercise Capacity","NOT_YET_RECRUITING","2025-07-09",{"date":89,"type":31},"2025-07-14",{"date":91,"type":20},"2025-07-15",{"date":93,"type":20},"2026-03",{"name":37,"class":38},""]