[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Lesaffre International\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":73},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100630866","a-decentralized-clinical-study-evaluating-the-effectiveness-of-two-different-doses-of-mycondro-on-physical-mobility-and-joint-health-100630866",false,"NCT07493239","A Decentralized Clinical Study Evaluating the Effectiveness of Two Different Doses of MyCondro™ on Physical Mobility and Joint Health","A Randomized, Double-blind Study Evaluating the Effectiveness of Two Different Doses of MyCondroTM on Physical Mobility and Joint Health Using Participant-Reported Outcomes in Individuals With Self-Reported Mobility Issues Associated With Knee Osteoarthritis","Inclusion Criteria:\n\n* Individuals age 45 years and older.\n* BMI range between 18-35 kg\u002Fm².\n* Self-reported mobility issues, including mobility impairment and joint discomfort associated with a known diagnosis of Knee Osteoarthritis. This impairment and discomfort must have persisted for at least 6 months prior to randomization and have been actively experienced within the last 3 months.\n* Willingness to avoid high Chondroitin Sulfate-containing foods (i.e., animal cartilages, bones, or derivatives such as gelatin) for the duration of the study period.\n* Willingness to refrain from supplements containing Chondroitin Sulfate for the duration of the study period.\n* Able to read and understand English.\n* Able to read, understand, and provide informed consent.\n* Able to use a personal smartphone device and download the Chloe by People Science app.\n* Able to receive shipments of the product at an address within the United States.\n* Able to complete study assessments over the course of up to 16 weeks.\n\nExclusion Criteria:\n\nAny potential participants will be excluded if they meet any of the following criteria:\n\n* Technology Limitation: Do not have a personal smartphone, lack internet access, or are unwilling to download the Chloe app.\n* Concomitant Therapies\n\n  1. Use of a Chondroitin Sulfate supplement in the 3 months prior to randomization.\n  2. Current use of other joint health supplements (e.g., glucosamine, hyaluronic acid, collagen peptides) for at least 4 weeks prior to randomization.\n  3. Use of any intra-articular or intravenous steroid injections in the last 3 months.\n  4. Receiving any investigational therapies or treatments within 30 days prior to randomization.\n\nOther Illnesses or Conditions\n\n1. Self-reported inflammatory arthropathies, such as Rheumatoid Arthritis, Gout, and Infectious Arthritis.\n2. Significant systemic lung, liver, heart, or kidney disease (excluding hypertension).\n3. Prior history of knee surgery within 3 months preceding the study period, or planned knee surgery (including arthroscopy) during the study period.\n4. Currently diagnosed with Alcohol Use Disorder and\u002For Substance Use Disorder.\n5. Currently pregnant, planning to become pregnant in the next 20 weeks, or breastfeeding.\n6. Presence of a knee prosthesis.\n7. Any significant illness, disease, or condition which, in the opinion of the Principal Investigator, may impact the ability to participate in the study or impact the study outcomes.\n\nAllergies and Intolerances\n\n1. Known hypersensitivity or previous allergic reaction to: Chondroitin sulfate, Maltodextrin, Mannitol, Magnesium Stearate, Silicon dioxide, Microcrystalline cellulose, or Talc.\n2. Known sensitivity or intolerance to wheat or gluten.\n\nGeneral Compliance\n\n1- Unlikely for any reason to be able to comply with the trial, or considered unsuited for participation in the study by the Principal Investigator.",true,"ALL","45 Years",{"count":20,"type":21},240,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study evaluates the effect of two different doses of a consumer-grade product, MyCondro™, on individuals experiencing mobility issues related to knee osteoarthritis. The primary goal is to measure improvements in overall joint health and mobility by tracking changes in participants' total WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) scores from the beginning to the end of the trial. Additionally, the study aims to assess secondary outcomes, including the product's impact on pain, stiffness, knee function, patient-reported improvement, inflammatory blood markers (CRP), and daily physical activity.",[27],"Joint Health",[29,30,31,32],"MyCondro, Gnosis, PS24","Joint function","Joint mobility","non-animal chondroitin sulfate","RECRUITING","2026-07-21",{"date":36,"type":37},"2026-07-22","ACTUAL",{"date":39,"type":37},"2026-03-04",{"date":41,"type":21},"2026-11-02",{"name":43,"class":44},"Lesaffre International","INDUSTRY",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":16,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":45},"100648847","a-clinical-trial-evaluating-the-influence-of-the-ingredients-mycondro-and-bovine-chondroitin-sulfate-on-the-behavior-of-cells-in-the-osteoarticular-sphere-100648847","NCT07727174","A Clinical Trial Evaluating the Influence of the Ingredients MyCondro™ and Bovine Chondroitin Sulfate on the Behavior of Cells in the Osteoarticular Sphere","Determination of the Biological Activity of Enriched Sera From Healthy Volunteers After Consumption of Chondroitin Sulfate of Both Animal and Fermentative Origin","Inclusion Criteria:\n\n* Men.\n* 18-35 years old (terminals included).\n* Liver test in the reference standards.\n* Renal assessment in the reference standards.\n* NFS in the reference standards.\n* CRP in the reference standards.\n* Blood pressure compatible with the conduct of the study.\n* Non-smoker or occasional smoker (\\\u003C5 cigarettes\u002Fday or \\\u003C 10ml per week of electronic cigarette liquid dosed at 3 mg\u002Fml of nicotine).\n* \\\u003C to 5 hours of intense sport per week.\n* Weight≥ to 60 kg.\n* BMI between 20 and 28 kg\u002Fm² (terminals not included).\n* Subjects able and willing to comply with the protocol and provide written informed consent.\n* Subjects affiliated to social security\n\nExclusion Criteria:\n\n* All types of vaccination under one month.\n* Alcohol consumption above WHO standards (\\>3 glasses of alcohol per day for men).\n* Ongoing treatment (medication, dietary supplement or probiotic) and within 4 weeks prior to inclusion.\n* Known pathology (including seasonal).\n* Allergy to the study product (all types)\n* People with a diet that is not suitable for the conduct of the study (e.g. vegetarian, vegan or vegan diet).\n* Change in eating habits in the 4 weeks prior to inclusion.\n* Medical and\u002For surgical history judged by the investigator or his\u002Fher representative to be incompatible with the trial.\n* Blood donation made in the 3 months prior to the inclusion visit or intending to do so during the study.\n* Persons under guardianship, curatorship, deprivation of liberty, safeguard of justice.\n* Refusal to sign the information sheet and consent.\n* Refusal to be registered on the National Register of Volunteers who lend themselves to research involving the human person.\n* Person who is excluded from another study on the national volunteer database, or who has received more than €6000 in the year following their participation in clinical studies.","MALE","18 Years","35 Years",{"count":57,"type":21},10,[24],"The study evaluates the effect of chondroitin sulfate derived from fermentation (MyCondro™) and bovine chondroitin sulfate, on the health and function of the skeletal system ex vivo, including cartilage, joint capsule, and bone tissue. The primary aim of the study is to determine the influence of human sera enriched with metabolites resulting from the ingestion of the ingredients on the metabolism of human primary cells of cartilage (chondrocytes), joint capsule (synoviocytes) and bone tissue (osteoblasts). Furthermore, the absorption kinetics of MyCondro™ and Bovine CS will be described.",[27],[31,62,32,63],"Joint health","MyCondro™","NOT_YET_RECRUITING","2026-07-20",{"date":67,"type":37},"2026-07-27",{"date":69,"type":21},"2026-08-26",{"date":71,"type":21},"2027-05",{"name":43,"class":44},""]