[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Maternity Hospital - State Budgetary Institution of the Rostov Region, Taganrog\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":52},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100658547","tap-vs-esp-blocks-for-post-cesarean-analgesia-a-randomized-controlled-trial-100658547",false,"NCT07853482","TAP vs. ESP Blocks for Post-Cesarean Analgesia","Comparative Efficacy of Transversus Abdominis Plane (TAP) and Erector Spinae Plane (ESP) Blocks for Postoperative Analgesia After Elective Cesarean Section: A Prospective, Single-Center, Randomized Controlled Trial","RCT-TAP-ESP-CS","Inclusion Criteria:\n\n1. Women aged 18 to 40 years.\n2. ASA physical status I-II.\n3. Scheduled for elective cesarean delivery under spinal anesthesia at term (37-41 weeks of gestation).\n4. Single fetus pregnancy.\n5. Provided written informed consent to participate in the study.\n\nExclusion Criteria:\n\n1. Emergency cesarean delivery.\n2. Contraindications to regional anesthesia (e.g., coagulation disorders, infection at the injection site, patient refusal).\n3. Known allergy to local anesthetics (ropivacaine, bupivacaine) or NSAIDs (ketoprofen).\n4. Chronic pain syndrome or regular use of opioid analgesics prior to surgery.\n5. BMI \\> 35 kg\u002Fm².\n6. Multiple pregnancy (twins, triplets, etc.).\n7. Pre-eclampsia or eclampsia.\n8. Inability to communicate or understand the pain assessment scales (NRS).\n9. Previous abdominal surgery with extensive adhesions that may alter anatomy for nerve blocks.","FEMALE","18 Years","40 Years",{"count":21,"type":22},162,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study compares the effectiveness of two ultrasound-guided nerve blocks (TAP block and ESP block) versus standard pain management for relieving pain after a planned cesarean section.\n\nCesarean delivery often causes moderate to severe pain, which can be divided into somatic pain (from the abdominal incision) and visceral pain (from uterine contractions and internal tissues). While transversus abdominis plane (TAP) blocks are commonly used, erector spinae plane (ESP) blocks are a newer technique that may provide better relief for visceral pain.\n\nIn this randomized controlled trial, 162 women undergoing elective cesarean delivery under spinal anesthesia will be assigned to one of three groups:\n\n1. Bilateral ESP block at the L1 level;\n2. Bilateral TAP block;\n3. Standard analgesia without nerve blocks.\n\nThe primary goal is to determine which method provides better control of visceral pain in the first 16 hours after surgery. Secondary goals include assessing somatic pain, time to first mobilization, time to first skin-to-skin contact with the baby, and the need for additional rescue pain medication. The study aims to support early recovery and improve mother-infant bonding by optimizing postoperative pain control.",[28],"Postoperative Pain After Cesarean Section",[30,31,32,33,34,35,36,37,38,39],"Cesarean section","postoperative pain","TAP block","ESP block","erector spinae plane block","transversus abdominis plane block","regional anesthesia","visceral pain","somatic pain","ropivacaine","NOT_YET_RECRUITING","2026-10-01",{"date":43,"type":44},"2026-10-06","ACTUAL",{"date":46,"type":22},"2026-10-15",{"date":48,"type":22},"2027-06-10",{"name":50,"class":51},"Maternity Hospital - State Budgetary Institution of the Rostov Region, Taganrog","OTHER_GOV",""]