[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"May University in Cairo\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100650691","blood-flow-restriction-training-in-women-with-posterior-tibial-tendon-dysfunction-100650691",false,"NCT07750106","Blood Flow Restriction Training in Women With Posterior Tibial Tendon Dysfunction","Effects of Blood Flow Restriction Training on Dynamic Postural Stability and Proprioception in Post-Menopausal Women With Posterior Tibial Tendon Dysfunction: A Randomized Controlled Trial","BFR-PTTD","Inclusion Criteria:\n\n* Female post-menopausal women aged 40-55 years.\n* Clinically diagnosed with Stage I or flexible Stage II posterior tibial tendon dysfunction according to the Johnson and Strom classification modified by Myerson confirmed by an orthopedic physician.\n* Symptoms persisting for ≥ 3 months.\n* Pain intensity of ≥3\u002F10 on the Visual Analogue Scale (VAS) during weight-bearing activities.\n* Medically cleared to participate in blood flow restriction resistance training.\n* Symptoms located at the medial ankle or foot.\n* Pain on palpation of the posterior tibial tendon.\n* A positive double and\u002For single heel-rise test.\n* Able to walk independently without assistive devices\n* Body Mass Index (BMI) between 18.5 and \\\u003C24.9 kg\u002Fm².\n* Willingness to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Rigidity of the hindfoot.\n* Pain on palpation of the fibular muscles.\n* History of corticosteroid injection in the tendon in a one-month period prior to the study onset.\n* History of surgery to the hindfoot and\u002For ankle.\n* History of previous surgeries to the musculoskeletal structures (i.e., bones, joint structures, nerves) in either limb of the lower extremities.\n* History of a fracture in either limb of the lower extremities requiring realignment.\n* Acute injury to musculoskeletal structures of other joints of the lower extremity in the previous three months, which impacted joint integrity and function (i.e., sprains, fractures) resulting in interruption of desired physical activity.\n* Hip joint or knee joint replacement.\n* Patients who were possibly at risk of adverse reactions of blood flow restriction (i.e., poor circulatory system, obesity, diabetes, arterial calcification, sickle cell trait, severe hypertension, or renal failure).\n* Any neurological conditions that affect proprioception, such as polyneuropathy, multiple sclerosis, and sensory ataxia.\n* Vestibular deficits and vision problems.","FEMALE","40 Years","55 Years",{"count":21,"type":22},54,"ESTIMATED","INTERVENTIONAL",[25],"NA","Posterior tibial tendon dysfunction (PTTD) is a common musculoskeletal disorder characterized by pain, impaired foot function, and reduced dynamic stability. As one of the primary causes of adult-acquired flatfoot deformity, it can significantly affect walking ability, balance, and overall performance of daily activities. Although conventional rehabilitation typically emphasizes strengthening the posterior tibial tendon and surrounding muscles, these interventions may not fully address deficits in neuromuscular control and postural stability, highlighting the need for additional therapeutic approaches.\n\nThis randomized controlled trial aims to evaluate whether incorporating blood flow restriction (BFR) training into a rehabilitation program provides additional benefits for postmenopausal women with Stage I or flexible Stage II PTTD. A total of 54 eligible participants will be randomly allocated to either a BFR training group or a conventional exercise group. Clinical outcomes will be assessed before and after the intervention, including dynamic postural stability measured with the Biodex Balance System and active and passive ankle joint position sense assessed using the Biodex Isokinetic Dynamometer.",[28],"Posterior Tibial Tendon Dysfunction",[28,30],"Blood Flow Restriction","NOT_YET_RECRUITING","2026-08-01",{"date":34,"type":35},"2026-08-06","ACTUAL",{"date":32,"type":22},{"date":38,"type":22},"2026-10-01",{"name":40,"class":41},"May University in Cairo","OTHER",""]