[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Mersin University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":694},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,37,0,25,[9,48,84,111,136,164,196,223,253,279,307,333,361,384,409,434,459,485,512,539,566,593,618,643,669],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100651262","comparison-of-sedated-and-unsedated-peg-in-elderly-asa-iv-patients-100651262",false,"NCT07758153","Comparison of Sedated and Unsedated PEG in Elderly ASA IV Patients","Comparison Of Safety And Clinical Outcomes Of Sedated And Unsedated Percutaneous Endoscopic Gastrostomy Procedures İn ASA IV Elderly Patients: A Prospective Observational Cohort Study.","Inclusion Criteria:\n\n* Patients aged 65 years and older Patients classified as ASA physical status IV Patients with an indication for percutaneous endoscopic gastrostomy for long-term enteral nutrition Patients scheduled to undergo PEG placement in routine clinical practice Written informed consent obtained from the patient or legally authorized representative Availability of clinical, laboratory, procedural, and follow-up data\n\nExclusion Criteria:\n\n* Requirement for emergency PEG placement International normalized ratio greater than 1.5 Platelet count less than 50,000\u002Fmm³ Massive ascites Active peritonitis Previous total gastrectomy Pregnancy Refusal to participate in the study","ALL","65 Years",{"count":20,"type":21},70,"ESTIMATED","OBSERVATIONAL","This prospective observational cohort study aims to compare the safety and clinical outcomes of sedated and unsedated percutaneous endoscopic gastrostomy procedures in elderly patients classified as ASA IV. The primary outcome is the development of cardiopulmonary complications within the first 24 hours after the procedure. Secondary outcomes include technical success, procedure duration, early procedure-related complications, length of hospital stay, intensive care requirement, 30-day mortality, and 30-day readmission.",[25,26,27,28,29],"Percutaneous Endoscopic Gastrostomy","Enteral Nutrition Feeding","Dysphagia","Elderly Patients (>65 Years)","ASA Physical Status IV",[31,32,33,34,35],"Percutaneous endoscopic gastrostomy","Sedation","Unsedated PEG","ASA IV","Cardiopulmonary complications","NOT_YET_RECRUITING","2026-08-06",{"date":39,"type":40},"2026-08-11","ACTUAL",{"date":42,"type":21},"2026-07-15",{"date":44,"type":21},"2027-07",{"name":46,"class":47},"Mersin University","OTHER",{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":12,"sex":17,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":69,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},"100648095","the-effect-of-breast-milk-10-and-20-dextrose-on-pain-and-physiological-variables-during-heel-puncture-in-infants-100648095","NCT07716813","The Effect of Breast Milk, 10% and 20% Dextrose on Pain and Physiological Variables During Heel Puncture in Infants","The Effect of Oral Breast Milk and 20% Dextrose Solution Administered With Supportive Positioning Methods on Pain and Physiological Variables During Heel Puncture Blood Sampling in Preterm Infants: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Parental consent for the baby's participation in the study\n* Admission to Mersin University Hospital NICU between July 16, 2026 and December 30, 2026,\n* Gestational age at birth between 33 weeks and 37 weeks,\n* Postnatal age less than 7 days,\n* Heel prick blood test planned within the scope of NTP,\n* Stable clinical condition,\n* Absence of genetic or metabolic problems,\n* Developed sucking-swallowing and breathing coordination,\n* Having been fed at least 30 minutes before the procedure,\n* No experience with invasive procedures in the last 6 hours before the procedure,\n* No administration of non-opioid analgesics in the last 4 hours before the procedure,\n* No administration of opioid analgesics and sedative agents in the last 24 hours before the procedure,\n* Spontaneous respiration at 21% FiO2,\n* Absence of neurological problems (e.g., asphyxia, hypoxic ischemic encephalopathy, intraventricular hemorrhage, periventricular leukomalacia, spinal cord injury…),\n* Absence of contraindications to oral glucose\u002Fbreast milk administration (e.g., necrotizing enterocolitis or suspicion thereof, feeding intolerance, tracheoesophageal fistula, absence of esophageal atresia…),\n* Absence of endocrine problems (e.g., hypoglycemia, hyperglycemia, large for gestational age, absence of a diabetic mother…),\n\nExclusion Criteria:\n\n* Parental disapproval of infant's participation in the study\n* No hospitalization at Mersin University Hospital NICUs between July 16, 2026 and December 30, 2026,\n* Gestational age at birth less than 33 weeks or greater than 37 weeks,\n* Postnatal age greater than 7 days,\n* Heel prick blood test not planned within the scope of NTP,\n* Clinical condition not stable,\n* Lack of developed sucking-swallowing and breathing coordination,\n* Having been fed within 30 minutes of the procedure,\n* Having had invasive procedures experience in the last 6 hours before the procedure,\n* Having received non-opioid analgesics in the last 4 hours before the procedure,\n* Having received opioid analgesics and sedative agents in the last 24 hours before the procedure,\n* Genetic or metabolic problem The following are contraindications:\n* Being on invasive or non-invasive mechanical ventilation support,\n* Having a neurological problem,\n* Oral glucose\u002Fbreast milk administration being contraindicated,\n* Having an endocrine and metabolic problem.","32 Weeks","37 Months",{"count":58,"type":21},96,"INTERVENTIONAL",[61],"NA","Pain, defined by the International Association for the Study of Pain as a subjective, sensory, and emotional experience, differs from nociception, which is merely a neural activity. Premature newborns, whose inhibitory fibers are not yet mature due to anatomical and physiological development and who have insufficient endogenous opioid release, experience painful stimuli much more intensely. The inability of this age group to verbally express pain makes the diagnosis, assessment, and management of pain entirely dependent on healthcare professionals. Pain that is not effectively managed leads to stress and loss of comfort in the short term, while in the long term it can cause permanent neurodevelopmental problems and alter the individual's pain threshold later in life.\n\nPremature infants, especially those in Neonatal Intensive Care Units (NICUs), are exposed to invasive procedures that cause moderate to severe pain, such as heel prick tests, much more frequently than healthy term infants. In this context, pain management is a fundamental and essential nursing responsibility for the infant's neuroprotective developmental care. The literature shows that various non-pharmacological methods, such as oral sucrose, non-nutritive sucking (NNS), facilitated flexion, and wrapping, are used to alleviate pain during interventional procedures. Although more readily available in NICUs, studies on the effectiveness of oral glucose solutions are more limited compared to sucrose.\n\nThis research, designed to address this gap in the existing literature, aims to investigate the effect of \"oral breast milk, 20%, and 10% dextrose solution administered with supportive positioning methods\" on pain reduction during heel prick blood sampling in premature newborns. The results of this research are expected to contribute to the development of a new, easily applicable, effective, and evidence-based nursing intervention strategy for NICUs.",[64,65,66,67,68],"Newborn Care","Pain Management","Physiological Parameters During Newborn Care İn Newborn's","Breast Milk","Premature",[70,71,72,73,74],"premature baby","pain","breast milk","nursing care","dextrose","2026-07-22",{"date":77,"type":40},"2026-07-24",{"date":79,"type":21},"2026-07-18",{"date":81,"type":21},"2026-09-30",{"name":46,"class":47},1,{"id":85,"slug":86,"hasResults":12,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":59,"phases":94,"briefSummary":95,"conditions":96,"keywords":99,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":4},"100588538","efficacy-of-genicular-block-on-total-knee-arthroplasty-surgery-100588538","NCT06942702","Efficacy of Genicular Block on Total Knee Arthroplasty Surgery","Assesment of Postoperative Analgesic Efficacy of Preoperatively Applied Genicular Block on Total Knee Arthroplasty: A Randomized Controlled Study","Inclusion Criteria:\n\n* Scheduled for unilateral and primary total knee arthroplasty\n* Older than 18 years of age\n\nExclusion Criteria:\n\n* Younger than 18 years\n* Bilateral knee arthroplasty\n* Revision case of knee arthroplasty","18 Years",{"count":93,"type":21},44,[61],"The aim of this study is to investigate the postoperative pain relieving effect of preoperative genicular block in total knee arthroplasty surgery. The main questions it aims to answer are:\n\n1. Do visual analog scale (VAS) scores decrease in patients who underwent geniculate block?\n2. Does opioid consumption decrease in patients who underwent geniculate block?\n\nResearchers will compare postoperative pain in patients who received genicular block with those who did not.One group of patients will be administered 0.25% bupivacaine with the geniculate block method. The other group will not undergo any intervention. Both groups will be administered intravenous morphine for postoperative analgesia.",[97,98],"Total Knee Anthroplasty","Genicular Nerves Block",[100,101,102],"total knee arthroplasty","genicular block","postoperative pain","2026-07-20",{"date":105,"type":40},"2026-07-21",{"date":107,"type":21},"2026-07-30",{"date":109,"type":21},"2026-12-20",{"name":46,"class":47},{"id":112,"slug":113,"hasResults":12,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":4,"enrollmentInfo":118,"targetDuration":120,"studyType":22,"phases":4,"briefSummary":121,"conditions":122,"keywords":126,"overallStatus":128,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":83},"100571508","phenol-or-laser-best-minimally-invasive-treatment-for-pilonidal-sinus-100571508","NCT06721169","Phenol or Laser: Best Minimally Invasive Treatment for Pilonidal Sinus?","Minimally Invasive Treatment of Pilonidal Sinus Disease: Which is Better? Phenol or Laser Ablation","Inclusion Criteria:\n\n* Patients aged 18 years and older with pilonidal sinus disease\n* Patients who have not had any previous treatment for pilonidal sinus disease\n* Patients with uncomplicated pilonidal sinus\n* Having been diagnosed with pilonidal sinus disease\n* Patients whose descriptive and clinical characteristics are recorded in their medical files\n* Those who have signed the Informed Voluntary Consent Form\u002FWritten Consent Form\n\nExclusion Criteria:\n\n* Patients who have previously been treated for pilonidal sinus disease\n* Patients with complicated pilonidal sinus disease\n* Patients aged under 18\n* Patients whose descriptive and clinical characteristics are not recorded in their file records\n* Those who have not signed the Informed Voluntary Consent Form\u002FWritten Consent Form",{"count":119,"type":21},64,"1 Year","Pilonidal sinus disease is a common condition. There is still ongoing research on the ideal treatment. Pilonidal sinus disease is most common in men between the ages of 20 and 30. For patients with symptoms of pilonidal sinüs (pain, itching and discharge with soiling of underwear) that interfere with their normal daily life, several treatment options have emerged. A hairy body, thick skin, overweight, a deep gluteal cleft, lack of hygiene, sedentarism, repeated chafing and previous familial history are commonly admitted as predisposing factors.\n\nThere are various surgical and non-surgical methods for its treatment. Many different surgical techniques have been defined. None of these surgical techniques are defined as 'gold standard'.\n\nFor many years, wide excision and secondary healing was the standard approach for pilonidal sinus disease. However, when this method resulted in prolonged healing and restriction of regular activities, various reconstructive methods were developed to demonstrate the disadvantages of secondary healing.\n\nA minimally invasive treatment modality for pilonidal sinüs dissease is excision of the sinus pit(s) followed by application of phenol to the sinus tract. Phenol is a sclerosing agent that destroys the epithelium and debris in the sinus, and is, thus, able to promote healing of the sinus.\n\nRecently, advances in laser technology have made laser ablation of the sinus tract possible. The aim is to destroy and obliterate the sinus tracts with thermal energy produced by the laser probe.\n\nThe aim of this prospective observational study was to compare phenolization and laser ablation in the treatment of pilonidal sinus disease.",[123,124,125],"Pilonidal Sinus Treatment","Pilonidal Sinus Disorder","Surgical Outcomes",[127],"Pilonidal Disease, Phenol, Laser Ablation","RECRUITING","2026-07-19",{"date":105,"type":40},{"date":132,"type":40},"2024-12-28",{"date":134,"type":21},"2026-11-15",{"name":46,"class":47},{"id":137,"slug":138,"hasResults":12,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":12,"sex":17,"minAge":143,"maxAge":144,"enrollmentInfo":145,"targetDuration":4,"studyType":59,"phases":146,"briefSummary":147,"conditions":148,"keywords":151,"overallStatus":128,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":83},"100632635","effects-of-cartoons--interactive-storytelling-on-fear-and-comfort-in-6-9-year-olds-during-nebulizer-treatment-100632635","NCT07516249","Effects of Cartoons & Interactive Storytelling on Fear and Comfort in 6-9 Year Olds During Nebulizer Treatment","The Effect of Cartoon Viewing and Breath-Synchronized Interactive Storytelling During Nebulizer Medication Administration on Fear, Emotional Behavior, and Comfort in 6-9 Year Old Children: A Randomized Controlled Study","Inclusion Criteria:\n\n* \\- Children aged 6-9 years\n* Scheduled to receive nebulizer inhalation therapy due to acute or chronic respiratory disease\n* Conscious, responsive to environmental stimuli, and able to communicate verbally or nonverbally\n* Without a diagnosed neurodevelopmental disorder (severe autism spectrum disorder, severe intellectual disability, etc.)\n* Without severe hearing or vision loss that would impair storytelling and visual material comprehension\n* Without signs of respiratory failure requiring emergency intervention during nebulizer administration\n* With written informed consent from a parent or legal guardian\n* Children who are willing to participate in the study after being given explanations appropriate to their age and developmental level.\n\nExclusion Criteria:\n\n* Patients who require emergency medical intervention during nebulizer application, such as severe respiratory distress, cyanosis, or significantly low oxygen saturation.\n* Patients who are unconscious or unable to respond adequately to environmental stimuli.","6 Years","9 Years",{"count":58,"type":21},[61],"Fear and anxiety experienced by children during inhalation therapy (using a nebulizer or vaporizer) are key factors that make treatment compliance difficult and reduce the quality of care. Young children, in particular, may perceive this process as \"threatening\" due to mask use, the noise produced by the device, and a sense of loss of control. This situation triggers a significant physiological stress response in the child.\n\nTherefore, in pediatric nursing, non-pharmacological methods that increase children's participation in treatment are of great importance. The literature indicates that interventions such as showing cartoons, playing music, and using distracting visual materials both reduce anxiety and improve stress indicators like heart rate. Additionally, therapeutic play has been proven to help children adapt to the hospital environment and soothe their emotional reactions.\n\nThis study aims to evaluate the effectiveness of a nursing intervention-designed to enhance children's physical comfort and manage their fear and anxiety during inhalation therapy-that is breath-synchronized, interactive, and story-based.",[149,150],"Distraction Methods","Nursing Care",[152,153,154,155,156],"Administration, Inhalation","Distraction methods","fear","comfort","cartoon","2026-07-17",{"date":103,"type":40},{"date":160,"type":40},"2026-04-23",{"date":162,"type":21},"2026-10-30",{"name":46,"class":47},{"id":165,"slug":166,"hasResults":12,"nctId":167,"briefTitle":168,"officialTitle":169,"acronym":4,"eligibilityCriteria":170,"healthyVolunteers":171,"sex":172,"minAge":91,"maxAge":173,"enrollmentInfo":174,"targetDuration":4,"studyType":59,"phases":176,"briefSummary":177,"conditions":178,"keywords":182,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":188,"lastUpdatePostDateStruct":189,"startDateStruct":191,"completionDateStruct":193,"leadSponsor":195,"locationsCount":4},"100645735","the-psychosocial-effects-of-prenatal-education-with-the-indivisible-self-model-100645735","NCT07699900","The Psychosocial Effects of Prenatal Education With the Indivisible Self Model","The Impact of a Prenatal Education Program Based on the Indivisible Self Model on Psychosocial Outcomes: A Randomized Controlled Study","Inclusion Criteria:\n\n* Between December 2025 and November 2026,\n* Living in the province of Aksaray,\n* Female,\n* Between the ages of 18-40,\n* Native language Turkish,\n* Between the 28th-32nd weeks of pregnancy,\n* In their first pregnancy,\n* With a singleton pregnancy,\n* Without any chronic disease or pregnancy complications,\n* Without any diagnosed active psychiatric disorder,\n* Having a mobile phone through which communication can be maintained,\n* Not having participated in another childbirth preparation program,\n* Not having participated in a prenatal psychoeducation and counseling program,\n* Planning the mode of delivery as vaginal birth , women will be included in the sample.\n\nExclusion Criteria:\n\nBetween December 2025 and November 2026,\n\n* Those whose native language is not Turkish,\n* Those who are male,\n* Those under 18 years of age or over 40,\n* Those whose pregnancy is less than 28 weeks or more than 32 weeks,\n* Those who have previously ended a pregnancy beyond 20 weeks with childbirth,\n* Those who are multiparous,\n* Those with multiple pregnancies,\n* Those with any chronic illness,\n* Those who experience any complication related to the mother or fetus\u002Fnewborn during the research process,\n* Those who need to undergo a cesarean section at any stage of pregnancy or childbirth,\n* Those who develop mental health deviations during the research process and require professional support,\n* Those who did not attend 80% of the training,\n* Those who cannot be reached during the data collection process,\n* Women who wish to withdraw from the study at any stage of the research will be excluded from the study.",true,"FEMALE","40 Years",{"count":175,"type":21},76,[61],"This study was designed to compare the effects of a prenatal education program based on the Indivisible Self Model with those of a needs-based prenatal education program on psychosocial outcomes among pregnant women.",[179,180,181],"Prenatal Education Program","Indivisible Self Model","Salutogenic Approach",[180,183,184,185,186,187],"prenatal education","psychological well-being","sense of consistency","perception of control and support","self-efficacy at birth","2026-07-11",{"date":190,"type":40},"2026-07-14",{"date":192,"type":21},"2026-10-15",{"date":194,"type":21},"2027-03-15",{"name":46,"class":47},{"id":197,"slug":198,"hasResults":12,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":171,"sex":172,"minAge":91,"maxAge":18,"enrollmentInfo":203,"targetDuration":4,"studyType":59,"phases":205,"briefSummary":206,"conditions":207,"keywords":211,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":188,"lastUpdatePostDateStruct":217,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":4},"100645710","the-effect-of-web-based-compassion-focused-structured-writing-programs-on-well-being-in-midwives-working-in-delivery-rooms-100645710","NCT07699887","The Effect of Web-Based Compassion-Focused Structured Writing Programs on Well-Being in Midwives Working in Delivery Rooms","The Effect of Web-Based Compassion-Focused Writing Program and Reflective Writing Program on Psychological Outcomes in Midwives Working in Delivery Rooms: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Working as a midwife in a delivery room between November 1, 2025, and February 15, 2027\n2. Native Turkish speaker\n3. Female\n4. Aged between 18-65 years\n5. Having at least a bachelor's degree in midwifery\n6. Having at least three years of delivery room experience\n7. No diagnosed psychological or psychiatric disorder\n8. Having the technical infrastructure to use a web-based program\n9. Ability to use a smartphone, tablet, or computer\n10. Voluntary agreement to participate in the study\n\nExclusion Criteria:\n\n1. Not working in a delivery room during the specified dates\n2. Not a native Turkish speaker\n3. Under 18 or over 65 years of age\n4. Male\n5. Changing clinical unit during the study\n6. Not completing all five intervention sessions\n7. Working less than 40 hours per week in the delivery room due to leave or reassignment\n8. Voluntary withdrawal from the study at any stage",{"count":204,"type":21},90,[61],"This randomized controlled trial aims to compare the effects of a web-based compassion-focused writing program and a reflective writing program on psychological well-being, self-compassion, postpartum trauma-related stress symptoms, and post-traumatic growth in midwives working in delivery rooms.",[208,209,210],"Psychological Well-being","Secondary Traumatic Stress","Occupational Stress",[212,213,214,215,216],"Compassion-focused writing","Reflective writing","Midwife","Psychological well-being","Trauma",{"date":190,"type":40},{"date":219,"type":21},"2026-10-01",{"date":221,"type":21},"2027-02-15",{"name":46,"class":47},{"id":224,"slug":225,"hasResults":12,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":12,"sex":17,"minAge":230,"maxAge":231,"enrollmentInfo":232,"targetDuration":4,"studyType":59,"phases":234,"briefSummary":235,"conditions":236,"keywords":238,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":245,"lastUpdatePostDateStruct":246,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":83},"100646395","the-effect-of-animated-videos-and-therapeutic-play-methods-on-emotional-expression-fear-and-anxiety-in-children-aged-4-8-years-during-the-throat-swab-procedure-100646395","NCT07693842","The Effect of Animated Videos and Therapeutic Play Methods on Emotional Expression, Fear and Anxiety in Children Aged 4-8 Years During the Throat Swab Procedure","The Effect of Animated Videos and Therapeutic Play Methods on Emotional Expression, Fear and Anxiety in Children Aged 4-8 Years During the Throat Swab Procedure: A Randomised Controlled Trial","Inclusion Criteria:\n\nChildren whose parents have provided written informed consent, who have had a throat swab taken at a paediatric clinic, who have verbally agreed to participate in the study, aged between 4 and 8 years, with no cognitive or neurological differences, with no visual or hearing impairment.\n\nExclusion Criteria:\n\nChildren whose parents have not provided written informed consent, who have not had a throat swab taken at a paediatric clinic, who have not verbally agreed to participate in the study, younger than 4 years or older than 8 years, with cognitive or neurological differences, with visual or hearing impairment.","4 Years","8 Years",{"count":233,"type":21},105,[61],"We planned a study to determine the effect of showing an animated video and using educational therapeutic play methods prior to throat swab procedures in children aged 4-8 years on the children's compliance with the procedure, as well as on their emotional expression, fear and anxiety levels, and to compare the superiority\u002Feffectiveness of these two methods against one another. The sample size for the study was determined using an a priori power analysis conducted with the G\\*Power (v3.1.9.7) programme. It is planned to include a total of 105 children, with at least 35 children in each group. The study will be conducted using a single-blind, parallel-group, three-group experimental design. By demonstrating the effects of two different modern approaches on children's compliance, fear, anxiety and emotional responses during the throat swab procedure, this study will contribute to the development of evidence-based, atraumatic care practices in paediatric clinics.",[237],"Taking a Throat Swab",[239,240,241,242,154,243,244],"throat swab","therapeutic play","animation video","child","emotional expression","anxiety","2026-07-05",{"date":247,"type":40},"2026-07-09",{"date":249,"type":21},"2026-07-25",{"date":251,"type":21},"2027-01-15",{"name":46,"class":47},{"id":254,"slug":255,"hasResults":12,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":4,"eligibilityCriteria":259,"healthyVolunteers":171,"sex":172,"minAge":91,"maxAge":173,"enrollmentInfo":260,"targetDuration":4,"studyType":59,"phases":262,"briefSummary":263,"conditions":264,"keywords":267,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":273,"lastUpdatePostDateStruct":274,"startDateStruct":276,"completionDateStruct":277,"leadSponsor":278,"locationsCount":4},"100646669","web-based-gamification-in-postpartum-hemorrhage-management-education-among-midwifery-students-100646669","NCT07688122","Web-Based Gamification in Postpartum Hemorrhage Management Education Among Midwifery Students","The Effect of Web-Based Gamification in Postpartum Hemorrhage Management Education on Knowledge Level, Motivation, Clinical Self-Efficacy, and Satisfaction Among Midwifery Students: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Living in Turkey\n* Aged between 18-40 years\n* Female\n* Native speaker of Turkish\n* Fourth-year undergraduate midwifery student\n* Having received basic education on postpartum hemorrhage within the curriculum\n* Having access to internet and digital devices (computer, tablet, or smartphone)\n* Voluntarily agreeing to participate in the study\n\nExclusion Criteria:\n\n* Not attending at least 80% of the training sessions\n* Not completing the data collection tools fully\n* Participating in another study or training related to postpartum hemorrhage management during the research period\n* Not accessing or completing the gamification modules (for the experimental group)\n* Withdrawing from the study at any stage",{"count":261,"type":21},128,[61],"This study was designed to compare the effects of web-based gamification and online classical teaching methods on knowledge level, motivation toward instructional materials, clinical self-efficacy, and satisfaction in midwifery students receiving postpartum hemorrhage management education.",[265,266],"Hemorrhage Management Training","Gamification in Health Education",[268,269,270,271,272],"postpartum hemorrhage","gamification","midwifery education","learning motivation","self-efficacy","2026-06-30",{"date":275,"type":40},"2026-07-07",{"date":219,"type":21},{"date":251,"type":21},{"name":46,"class":47},{"id":280,"slug":281,"hasResults":12,"nctId":282,"briefTitle":283,"officialTitle":284,"acronym":4,"eligibilityCriteria":285,"healthyVolunteers":12,"sex":17,"minAge":230,"maxAge":286,"enrollmentInfo":287,"targetDuration":4,"studyType":59,"phases":289,"briefSummary":290,"conditions":291,"keywords":294,"overallStatus":128,"whyStopped":4,"lastUpdateSubmitDate":299,"lastUpdatePostDateStruct":300,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":83},"100643983","distraction-cards-versus-emotion-regulation-toy-squeezing-during-intramuscular-vaccination-in-preschool-children-100643983","NCT07669961","Distraction Cards Versus Emotion-Regulation Toy Squeezing During Intramuscular Vaccination in Preschool Children","The Effect of Using Distraction Card and Squeezing Emotion-Regulation Toy on Pain and Pain-Related Fear During Intramuscular Vaccination in Children Aged 4-7 Years: A Single-Center, Parallel-Group, Randomized Experimental Study","Inclusion Criteria:\n\n* Child aged 4-7 years\n* Child with need or plan for intramuscular vaccination\n\nExclusion Criteria:\n\n* Child with a neurodegenerative disease, mental retardation, vision and hearing problems, chronic, life-threatening (sepsis, shock, respiratory \u002F cardiac arrest) or genetic disease\n* Child with use of opioids, narcotics, analgesics or sedatives in the last 24 hours before the procedure","7 Years",{"count":288,"type":21},68,[61],"This single-center, parallel-group, randomized experimental study will compare the effects of two active non-pharmacological interventions - distraction-card use and emotion-regulation toy squeezing - on procedural pain and pain-related fear during intramuscular tetanus vaccination in children aged 4-7 years. Eligible children will be randomized to either the distraction-card group or the emotion-regulation toy-squeezing group. Pain will be assessed using the Wong-Baker FACES Pain Rating Scale, and pain-related fear will be assessed using the Children's Fear Scale before, during, and after the intramuscular injection procedure.\n\nHypotheses\n\n* H1a: There is a difference between the groups in mean Wong-Baker FACES scores during the procedure.\n* H1b: There is a difference between the groups in mean Children's Fear Scale scores during the procedure.",[292,293],"Procedural Pain","Pain-related Fear",[242,295,296,297,298],"pediatric nursing","intramuscular vaccination","distraction methods","active distraction","2026-06-25",{"date":301,"type":40},"2026-06-29",{"date":303,"type":40},"2026-06-21",{"date":305,"type":21},"2026-11-20",{"name":46,"class":47},{"id":308,"slug":309,"hasResults":12,"nctId":310,"briefTitle":311,"officialTitle":312,"acronym":4,"eligibilityCriteria":313,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":4,"enrollmentInfo":314,"targetDuration":4,"studyType":59,"phases":316,"briefSummary":317,"conditions":318,"keywords":320,"overallStatus":128,"whyStopped":4,"lastUpdateSubmitDate":325,"lastUpdatePostDateStruct":326,"startDateStruct":328,"completionDateStruct":330,"leadSponsor":332,"locationsCount":83},"100630560","effect-of-mobile-application--and-ai-supported-video-based-patient-education-on-patient-outcomes-in-teaching-clean-intermittent-catheterization-100630560","NCT07489261","Effect of Mobile Application- and AI Supported Video-Based Patient Education on Patient Outcomes in Teaching Clean Intermittent Catheterization","Effect of Mobile Application- and Artificial Intelligence-Supported Video-Based Patient Education on Patient Outcomes in Teaching Clean Intermittent Catheterization","Inclusion Criteria:\n\n* Patients who require intermittent catheterization (TAK),\n* Aged 18 years or older,\n* Willing to participate in the study,\n* Able to understand Turkish,\n* Literate,\n* Without visual or hearing impairments,\n* Owning a smartphone, tablet, or computer,\n* Without difficulties using technology.\n\nExclusion Criteria:\n\n* Patients who do not require intermittent catheterization (TAK),\n* Under 18 years of age,\n* Not willing to participate in the study,\n* Do not understand Turkish,\n* Illiterate,\n* With visual or hearing impairments,\n* Do not own a smartphone, tablet, or computer,\n* Having difficulties using technology.",{"count":315,"type":21},99,[61],"The study aimed to determine the effects of a mobile application and an artificial intelligence-supported educational video, developed for patients who will perform clean intermittent catheterization (CIC), on patients' adherence, levels of difficulty, self-confidence, infection parameters (urinalysis, urine culture, infection incidence), and recurrent hospital admissions.The number of CIC patients who applied to the Urology Outpatient Clinic of Mersin University within the last year was 110. Since no similar study was found, the sample size was calculated using an a priori power analysis with G\\*Power 3.1.9.7 software. . As a result of the power analysis, the total sample size was calculated as 90, with 30 participants in each group. Considering a possible data loss (dropout) rate of approximately 10%, it was planned to include 33 participants in each group (a total of 99 participants) at the beginning of the study.Data will be collected using the \"Descriptive Information Form,\" \"Intermittent Catheterization Adherence Scale,\" \"Self-Confidence Scale in Clean Intermittent Self-Catheterization,\" \"Intermittent Catheterization Difficulty Questionnaire,\" and the \"Patient Follow-up Form.\"Patients who will perform clean intermittent catheterization will receive training through a mobile application (intervention group 1) and an artificial intelligence-supported educational video (intervention group 2). Patients in the control group will be trained using the routine brochure provided in the outpatient clinic.",[319],"Clean Intermittent Catheterization",[321,322,323,324],"Mobile application","Artificial intelligience","Patient Outcome","Patient Education","2026-06-19",{"date":327,"type":40},"2026-06-24",{"date":329,"type":40},"2026-04-01",{"date":331,"type":21},"2027-04-01",{"name":46,"class":47},{"id":334,"slug":335,"hasResults":12,"nctId":336,"briefTitle":337,"officialTitle":338,"acronym":339,"eligibilityCriteria":340,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":4,"enrollmentInfo":341,"targetDuration":4,"studyType":59,"phases":343,"briefSummary":344,"conditions":345,"keywords":348,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":353,"lastUpdatePostDateStruct":354,"startDateStruct":356,"completionDateStruct":358,"leadSponsor":360,"locationsCount":83},"100631974","the-effect-of-a-stress-ball-applied-before-retrograde-intrarenal-surgery-on-anxiety-surgical-fear-and-hemodynamic-parameters-100631974","NCT07507656","The Effect of a Stress Ball Applied Before Retrograde Intrarenal Surgery on Anxiety, Surgical Fear, and Hemodynamic Parameters","The Effect of a Stress Ball Applied Before Retrograde Intrarenal Surgery on Anxiety, Surgical Fear, and Hemodynamic Parameters: A Randomized Controlled Trial","Stress ball","Inclusion Criteria:\n\nPatients to be included in the study are those who:\n\n* Are scheduled to undergo Retrograde Intrarenal Surgery (RIRS),\n* Are 18 years of age or older,\n* Are conscious and cooperative,\n* Speak and understand Turkish,\n* Have stable general condition and hemodynamic parameters,\n* Are scheduled for an elective surgical procedure,\n* Have no psychiatric diagnosis,\n* Are not using psychiatric and\u002For local neuromuscular blocking medications,\n* Provide informed consent to participate in the study (have signed the Informed Consent Form).\n\nExclusion Criteria:\n\nPatients who will not be included in the study are those who:\n\n* Are under 18 years of age,\n* Are not conscious or cooperative,\n* Do not speak or understand Turkish,\n* Have unstable general condition or hemodynamic parameters,\n* Are undergoing emergency surgical procedures,\n* Have an existing psychiatric diagnosis,\n* Are using psychiatric and\u002For local neuromuscular blocking medications,\n* Do not consent to participate in the study (have not signed the Informed Consent Form).",{"count":342,"type":21},66,[61],"This study was designed as a randomized controlled trial to determine the effect of a stress ball applied before retrograde intrarenal surgery on patients' anxiety levels, surgical fear, and hemodynamic parameters.",[346,347],"Anxiety","Fear",[349,350,244,351,352],"Retrograde intrarenal surgery","stress ball","surgical fear","hemodynamic parameters","2026-04-02",{"date":355,"type":40},"2026-04-08",{"date":357,"type":21},"2026-04-16",{"date":359,"type":21},"2027-04-16",{"name":46,"class":47},{"id":362,"slug":363,"hasResults":12,"nctId":364,"briefTitle":365,"officialTitle":366,"acronym":339,"eligibilityCriteria":367,"healthyVolunteers":12,"sex":368,"minAge":91,"maxAge":4,"enrollmentInfo":369,"targetDuration":4,"studyType":59,"phases":371,"briefSummary":365,"conditions":372,"keywords":374,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":377,"lastUpdatePostDateStruct":378,"startDateStruct":379,"completionDateStruct":381,"leadSponsor":383,"locationsCount":83},"100631971","the-effect-of-using-a-stress-ball-during-transrectal-ultrasound-guided-prostate-biopsy-on-anxiety-pain-and-hemodynamic-variables-100631971","NCT07507617","The Effect of Using a Stress Ball During Transrectal Ultrasound-Guided Prostate Biopsy on Anxiety, Pain, and Hemodynamic Variables","The Effect of Using a Stress Ball During Transrectal Ultrasound-Guided Prostate Biopsy on Anxiety, Pain, and Hemodynamic Variables: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18 years or older,\n* Conscious and cooperative,\n* Able to speak and understand Turkish,\n* With stable general condition and hemodynamic variables,\n* Scheduled for the procedure,\n* Without any psychiatric diagnosis,\n* Not using psychiatric and\u002For local neuromuscular blocking medications,\n* Willing to participate in the study (having signed the Informed Consent Form).\n\nExclusion Criteria:\n\n* Under 18 years of age,\n* Not conscious or not cooperative,\n* Unable to speak or understand Turkish,\n* With unstable general condition or hemodynamic variables,\n* Undergoing emergency surgical procedures,\n* Having a current psychiatric diagnosis,\n* Using psychiatric and\u002For local neuromuscular blocking medications,\n* Unwilling to participate in the study (not signing the Informed Consent Form).","MALE",{"count":370,"type":21},72,[61],[373],"Stress",[375,376,373,339],"Biopsy","Pain","2026-03-27",{"date":353,"type":40},{"date":380,"type":21},"2026-04-06",{"date":382,"type":21},"2027-04-06",{"name":46,"class":47},{"id":385,"slug":386,"hasResults":12,"nctId":387,"briefTitle":388,"officialTitle":389,"acronym":4,"eligibilityCriteria":390,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":391,"enrollmentInfo":392,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":394,"conditions":395,"keywords":399,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":403,"lastUpdatePostDateStruct":404,"startDateStruct":405,"completionDateStruct":406,"leadSponsor":408,"locationsCount":83},"100631040","patient-satisfaction-during-lomber-transforaminal-epidural-steroid-injection-the-role-of-sedation-anxiety-and-pain-100631040","NCT07495501","Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain","Patient Satisfaction During Lomber Transforaminal Epidural Steroid Injection: The Role of Sedation, Anxiety, and Pain: A Prospective Observational Study","Inclusion Criteria:\n\n* Adults aged 18 to 80 years\n* No prior history of any interventional pain procedure\n* Ability to read and write in Turkish and to complete the study questionnaires\n* Written informed consent provided.\n* Planned lumbar transforaminal epidural steroid injection for radicular pain\n\nExclusion Criteria:\n\n* Refusal to provide written informed consent.\n* Inability to complete the satisfaction questionnaires reliably due to lack of Turkish literacy, significant cognitive impairment or severe visual or hearing impairment\n* Presence of major comorbidities such as decompensated cardiac or respiratory failure, uncontrolled arrhythmia or angina, myocardial infarction or stroke within the past 3 months, advanced liver or kidney failure, uncontrolled obstructive sleep apnea associated with morbid obesity, or severe pulmonary hypertension.","80 Years",{"count":393,"type":21},120,"Transforaminal epidural steroid injection (TFESI) is a minimally invasive procedure commonly used for the management of lumbar radicular pain. It is intended to reduce inflammation around the affected nerve root, limit edema, and modulate nociceptive transmission, with the aim of relieving pain, improving physical function, and potentially reducing the need for surgery. Although TFESI may improve function and quality of life, treatment benefit is not uniform, and the degree of pain relief and patient satisfaction may differ across individuals.\n\nThis prospective observational study aims to evaluate postprocedural pain intensity and patient satisfaction in individuals undergoing lumbar TFESI and to identify clinical and demographic factors associated with satisfaction. Demographic and clinical characteristics, medical and surgical history, procedural pain scores, anxiety level, postprocedural pain scores, sedation status, fluoroscopy-related metrics, and intraprocedural events will be recorded. Patient satisfaction will be assessed 1 hour after the procedure using a Likert-based questionnaire, and operator satisfaction will also be documented.\n\nBy examining patient-reported outcomes together with procedural and clinical variables, this study seeks to provide a more standardized assessment of real-world TFESI outcomes and to support better patient selection and follow-up strategies.",[396,397,398],"Lumbar Disc Disease","Radiculopathy Lumbar","Radicular Pain",[400,32,346,401,402],"Patient satisfaction","Epidural steroid injection","Pain intensity","2026-03-21",{"date":377,"type":40},{"date":329,"type":21},{"date":407,"type":21},"2026-09-15",{"name":46,"class":47},{"id":410,"slug":411,"hasResults":12,"nctId":412,"briefTitle":413,"officialTitle":414,"acronym":415,"eligibilityCriteria":416,"healthyVolunteers":171,"sex":17,"minAge":91,"maxAge":4,"enrollmentInfo":417,"targetDuration":4,"studyType":59,"phases":418,"briefSummary":419,"conditions":420,"keywords":422,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":426,"lastUpdatePostDateStruct":427,"startDateStruct":429,"completionDateStruct":431,"leadSponsor":433,"locationsCount":4},"100627884","the-effect-of-music-on-anxiety-levels-and-sleep-quality-in-patients-who-have-a-myocardial-infarction-100627884","NCT07454434","The Effect of Music on Anxiety Levels and Sleep Quality in Patients Who Have a Myocardial Infarction","The Effect of Music on Anxiety Levels and Sleep Quality During the First Night in the Coronary Care Unit in Patients Who Have a Myocardial Infarction","Anxiety Sleep","Inclusion Criteria:\n\n* Admitted to the coronary care unit with a diagnosis of MI,\n* Aged 18 years or older,\n* Conscious, oriented, and cooperative,\n* Able to read and understand Turkish,\n* Agreeing to participate in the study,\n* Having no physical condition that would prevent listening to music,\n* Having no diagnosis of hearing loss,\n* Not using a hearing aid,\n* Having no diagnosis of anxiety disorder,\n* Not diagnosed with a sleep disorder,\n* Not taking medication for anxiety or sleep disorders,\n* Without mental illness,\n* With a State Anxiety Scale (SAS) total score of 60 or below,\n* Who agree to participate in the study (by signing the Informed Consent Form) will be included.\n\nExclusion Criteria:\n\n* Admitted to the coronary care unit (CCU) for reasons other than MI diagnosis,\n* Under 18 years of age,\n* Unconscious, disoriented, and uncooperative,\n* Unable to read and understand Turkish,\n* Refusing to participate in the study,\n* Having a physical condition that prevents listening to music,\n* Diagnosed with hearing loss,\n* Using a hearing aid,\n* Diagnosed with an anxiety disorder or taking medication for anxiety,\n* Diagnosed with a sleep disorder or taking medication for a sleep disorder,\n* With a mental disorder,\n* With a State Anxiety Scale (SAS) total score of 60 or above,\n* Patients who do not agree to participate in the study (who do not sign the Informed Consent Form) will not be included in the study.",{"count":119,"type":21},[61],"Music therapy is a non-invasive method with no side effects and can be administered independently by a nurse. Nevertheless, it should be noted that music therapy can be discontinued if any adverse effects are experienced by patients during the research process. After completing the music listening session, eye masks and earplugs, which are effective in reducing sleep problems in patients, will be applied from 11:00 p.m. to 7:00 a.m.\n\nAll patients will be asked to complete the DAÖ at 10:00 PM and 10:30 PM. The RCUÖ will be requested to be completed by all patients between 8:00 AM and 9:00 AM the following morning.",[421,346],"Sleep Quality",[423,424,425,244],"music listening","nursing","sleep","2026-03-03",{"date":428,"type":40},"2026-03-06",{"date":430,"type":21},"2026-02-23",{"date":432,"type":21},"2026-08-30",{"name":46,"class":47},{"id":435,"slug":436,"hasResults":12,"nctId":437,"briefTitle":438,"officialTitle":439,"acronym":440,"eligibilityCriteria":441,"healthyVolunteers":171,"sex":17,"minAge":91,"maxAge":391,"enrollmentInfo":442,"targetDuration":4,"studyType":59,"phases":444,"briefSummary":445,"conditions":446,"keywords":448,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":451,"lastUpdatePostDateStruct":452,"startDateStruct":454,"completionDateStruct":456,"leadSponsor":458,"locationsCount":4},"100623470","mindfulness-based-nursing-care-and-anxiety-in-open-heart-surgery-patients-100623470","NCT07397052","Mindfulness-Based Nursing Care and Anxiety in Open Heart Surgery Patients","The Effect of Mindfulness-Based Nursing Intervention on Anxiety and Vital Signs in Patients Undergoing Open Heart Surgery: A Randomized Controlled Trial","OH-MIND","Inclusion Criteria:\n\n* Having a planned elective open heart surgery\n\n  * Being able to communicate in Turkish and understand the given instructions\n  * Being conscious, cooperative and oriented\n  * Having agreed to participate in the research in the preoperative period\n  * Being extubated and hemodynamically stable in the postoperative period\n\nExclusion Criteria:\n\n* Patients with pre-existing serious psychiatric illnesses (e.g., schizophrenia, bipolar disorder)\n\n  * Patients with cognitive impairment or those unable to complete the STAI-S scale\n  * Patients with neurological or sensory problems that impair hearing, speech, or communication\n  * Patients requiring long-term mechanical ventilation in the postoperative period\n  * Patients requiring re-intubation in the postoperative period\n  * Patients with hemodynamic instability or those monitored under deep sedation in the intensive care unit\n  * Patients who develop serious postoperative complications (e.g., stroke, massive bleeding)\n  * Patients who refuse to participate in the study or wish to withdraw from the study",{"count":443,"type":21},60,[61],"This randomized controlled trial aims to evaluate the effect of a mindfulness-based nursing intervention on anxiety levels and vital signs in patients undergoing open-heart surgery during the preoperative and early postoperative periods.",[447,346],"Open Heart Surgery",[449,346,450,150],"Mindfulness","Vital Signs","2026-02-05",{"date":453,"type":40},"2026-02-09",{"date":455,"type":21},"2026-02-10",{"date":457,"type":21},"2026-05-20",{"name":46,"class":47},{"id":460,"slug":461,"hasResults":12,"nctId":462,"briefTitle":463,"officialTitle":464,"acronym":465,"eligibilityCriteria":466,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":4,"enrollmentInfo":467,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":469,"conditions":470,"keywords":473,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":478,"lastUpdatePostDateStruct":479,"startDateStruct":480,"completionDateStruct":482,"leadSponsor":484,"locationsCount":83},"100623702","pldd-with-or-without-transforaminal-epidural-steroid-injection-in-lumbar-disc-herniation-100623702","NCT07400068","PLDD With or Without Transforaminal Epidural Steroid Injection in Lumbar Disc Herniation","Effect of Adjunct Transforaminal Anterior Epidural Steroid Injection Following Percutaneous Laser Disc Decompression in Patients With Single-Level Lumbar Disc Herniation: A Prospective Observational Study","PLDD-TFESI","Inclusion Criteria:\n\nAge 18 years and older\n\nDiagnosis of single-level lumbar disc herniation confirmed by magnetic resonance imaging (MRI)\n\nPresence of radicular leg pain refractory to conservative treatment\n\nUndergoing routine percutaneous laser disc decompression (PLDD) as part of standard clinical care\n\nAbility to provide informed consent\n\nExclusion Criteria:\n\nMultilevel lumbar disc herniation\n\nExtruded or sequestered disc herniation\n\nSevere spinal canal stenosis or spinal instability\n\nPrevious lumbar spine surgery at the affected level\n\nActive infection or systemic inflammatory disease\n\nCoagulopathy or use of anticoagulant therapy contraindicating intervention\n\nPregnancy\n\nInability to complete follow-up assessments",{"count":468,"type":21},88,"This prospective observational study aims to evaluate the clinical outcomes of patients with single-level lumbar disc herniation who undergo routine percutaneous laser disc decompression (PLDD).\n\nIn routine clinical practice, some patients receive an additional transforaminal anterior epidural steroid injection during the same session without an extra puncture. This study will prospectively follow patients who receive PLDD alone and those who receive PLDD combined with epidural steroid injection.\n\nPain intensity, functional status, analgesic use, need for additional interventions, and complications will be assessed over time. The results may help to clarify whether adding epidural steroid injection to PLDD improves clinical outcomes in patients with lumbar disc herniation.",[471,472],"Lumbar Disc Herniation","Lumbar Radiculopathy",[474,475,476,398,477],"Percutaneous Laser Disc Decompression","Transforaminal Epidural Steroid Injection","Minimally Invasive Spine Treatment","PLDD","2026-02-03",{"date":455,"type":40},{"date":481,"type":21},"2026-03-01",{"date":483,"type":21},"2027-09-01",{"name":46,"class":47},{"id":486,"slug":487,"hasResults":12,"nctId":488,"briefTitle":489,"officialTitle":490,"acronym":491,"eligibilityCriteria":492,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":4,"enrollmentInfo":493,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":495,"conditions":496,"keywords":501,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":478,"lastUpdatePostDateStruct":508,"startDateStruct":509,"completionDateStruct":510,"leadSponsor":511,"locationsCount":83},"100623701","mri-evaluation-of-spinal-cord-edema-after-ct-guided-percutaneous-cordotomy-in-cancer-pain-patients-100623701","NCT07400055","MRI Evaluation of Spinal Cord Edema After CT-Guided Percutaneous Cordotomy in Cancer Pain Patients","Evaluation of Medulla Spinalis Edema After CT-Guided Percutaneous Cervical Cordotomy Using Magnetic Resonance Imaging and Its Association With Postprocedural Clinical Outcomes in Patients With Cancer Pain","CORD-MRI","Inclusion Criteria:\n\nAdults aged 18 years and older\n\nPatients with cancer-related pain refractory to medical treatment\n\nPatients scheduled to undergo CT-guided percutaneous cervical cordotomy as part of routine clinical care\n\nAbility to provide informed consent\n\nAvailability for postoperative MRI follow-up on day 1 and at 1 month\n\nExclusion Criteria:\n\nPatients younger than 18 years\n\nPatients without an indication for percutaneous cervical cordotomy\n\nInability to undergo MRI (e.g., incompatible implants, severe claustrophobia)\n\nPatients who decline participation or withdraw consent\n\nIncomplete clinical or imaging follow-up data",{"count":494,"type":21},15,"This observational study aims to evaluate changes in the spinal cord following CT-guided percutaneous cervical cordotomy performed for the treatment of intractable cancer-related pain. Cordotomy is a routine clinical procedure used to relieve severe pain in selected cancer patients. After the procedure, some patients may develop temporary neurological symptoms that are thought to be related to spinal cord edema.\n\nIn this study, magnetic resonance imaging (MRI) will be performed as part of routine clinical follow-up on postoperative day 1 and at 1 month to assess the presence and extent of spinal cord edema. Clinical outcomes, including pain intensity and possible postprocedural symptoms, will be recorded and compared with MRI findings.\n\nThe goal of this research is to better understand the relationship between imaging changes in the spinal cord and clinical outcomes after cordotomy, which may help improve patient care and postoperative management in the future.",[497,498,499,500],"Cancer Pain","Intractable Pain","Spinal Cord Edema","Neuropathic Pain",[502,503,504,505,506,507],"Percutaneous Cordotomy","CT-guided Cordotomy","Cervical Cordotomy","Spinal Cord MRI","Radiofrequency Ablation","Postprocedural Complications",{"date":455,"type":40},{"date":481,"type":21},{"date":331,"type":21},{"name":46,"class":47},{"id":513,"slug":514,"hasResults":12,"nctId":515,"briefTitle":516,"officialTitle":517,"acronym":518,"eligibilityCriteria":519,"healthyVolunteers":171,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":520,"targetDuration":4,"studyType":59,"phases":522,"briefSummary":523,"conditions":524,"keywords":526,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":531,"lastUpdatePostDateStruct":532,"startDateStruct":534,"completionDateStruct":536,"leadSponsor":538,"locationsCount":4},"100621265","effects-of-ctrus-and-clove-ol-aromatherapy-n-older-adults-100621265","NCT07368374","EFFECTS OF CİTRUS AND CLOVE OİL AROMATHERAPY İN OLDER ADULTS","THE EFFECTS OF CİTRUS AND CLOVE OİL AROMATHERAPY ON FATİGUE LEVEL, SLEEP, AND QUALİTY OF LİFE İN OLDER ADULTS","ARTICLE","Inclusion Criteria:\n\n* Individuals who are: • 65 years of age or older\n\n  * Registered at the 60+ Refreshment University campus\n  * Can understand and communicate in Turkish\n  * Have a score of ≥24 on the Standardized Mini Mental State Examination (SMMT)\n  * Have a visual similarity scale (VAS-S) score of 4 or higher for sleep problems within the past week\n  * Have a visual similarity scale (VAS-F) score of 4 or higher for fatigue level within the past week\n  * Have agreed to participate in the study will be included in the study.\n\nExclusion Criteria:\n\n* Those with a known allergy\u002Fsensitivity to citrus or clove oil,\n* Those diagnosed with any respiratory disease (asthma, COPD, etc.),\n* Those with any health condition that impairs their ability to smell will not be included in the study.",{"count":521,"type":21},51,[61],"This study aimed to determine the effects of citrus and clove oil aromatherapy, administered via inhalation (2 drops, 2 minutes, 3 times a week for one month), on fatigue level, sleep quality, and quality of life in older adults.\n\nResearch Hypotheses\n\nH11: Inhalation aromatherapy with 2 drops of pure citrus oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is effective on fatigue level in older adults.\n\nH01: Inhalation aromatherapy with 2 drops of pure citrus oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is not effective on fatigue level in older adults.\n\nH12: Inhalation aromatherapy with 2 drops of pure citrus oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is effective on sleep quality in older adults.\n\nH02: Inhalation aromatherapy with 2 drops of pure citrus oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is not effective on sleep quality in older adults.\n\nH13: Inhalation aromatherapy with 2 drops of pure citrus oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is effective on quality of life in older adults.\n\nH03: Inhalation aromatherapy with 2 drops of pure citrus oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is not effective on quality of life in older adults.\n\nH14: Inhalation aromatherapy with 2 drops of pure clove oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is effective on fatigue level in older adults.\n\nH04: Inhalation aromatherapy with 2 drops of pure clove oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is not effective on fatigue level in older adults.\n\nH15: Inhalation aromatherapy with 2 drops of pure clove oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is effective on sleep quality in older adults.\n\nH05: Inhalation aromatherapy with 2 drops of pure clove oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is not effective on sleep quality in older adults.\n\nH16: Inhalation aromatherapy with 2 drops of pure clove oil administered for 2 minutes, 3 times a week, for a total of 12 sessions over one month is effective on quality of life in older adults.",[525],"Aromatherapy",[527,528,529,530],"aromatherapy","citrus oil","clove oil","older adults","2026-01-18",{"date":533,"type":40},"2026-01-26",{"date":535,"type":21},"2026-02-01",{"date":537,"type":21},"2026-12-30",{"name":46,"class":47},{"id":540,"slug":541,"hasResults":12,"nctId":542,"briefTitle":543,"officialTitle":544,"acronym":4,"eligibilityCriteria":545,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":391,"enrollmentInfo":546,"targetDuration":4,"studyType":59,"phases":548,"briefSummary":549,"conditions":550,"keywords":554,"overallStatus":128,"whyStopped":4,"lastUpdateSubmitDate":558,"lastUpdatePostDateStruct":559,"startDateStruct":561,"completionDateStruct":563,"leadSponsor":565,"locationsCount":83},"100564928","comparison-of-vascular-catheter-related-thrombosis-and-risk-factors-after-oncologic-and-non-oncologic-major-surgery-100564928","NCT06635551","Comparison of Vascular Catheter-Related Thrombosis and Risk Factors After Oncologic and Non-Oncologic Major Surgery","Comparison of Vascular Catheter-Related Thrombosis and Risk Factors Using Daily Bedside Ultrasonography After Oncologic and Non-Oncologic Major Surgery","Inclusion Criteria:\n\n* Adult patient (18-80 years old)\n* No hematological disease causing hypercoagulability\n* Not receiving anticoagulant\u002Fantifibrinolytic medications at the therapy dose\n* The vascular structure can be visualized with US\n* No thrombosis in the US control before catheter placement\n* The catheter is not inserted for renal replacement therapy\n\nExclusion Criteria:\n\n* Presence of renal failure\n* Pediatric patients\n* Presence of hematological malignancy\n* Inadequate US imaging",{"count":547,"type":21},100,[61],"The aim of this study was to prospectively evaluate vascular catheter-related thrombosis and risk factors using daily bedside ultrasonography after oncologic and non-oncologic major surgery.",[551,552,553],"Catheter Related Complication","Thromboses, Venous","Surgery",[555,556,557],"Central Venous Catheters","Venous Thrombosis","Ultrasonography","2025-12-04",{"date":560,"type":40},"2025-12-05",{"date":562,"type":40},"2024-12-04",{"date":564,"type":21},"2026-02",{"name":46,"class":47},{"id":567,"slug":568,"hasResults":12,"nctId":569,"briefTitle":570,"officialTitle":571,"acronym":4,"eligibilityCriteria":572,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":573,"enrollmentInfo":574,"targetDuration":4,"studyType":59,"phases":576,"briefSummary":577,"conditions":578,"keywords":580,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":585,"lastUpdatePostDateStruct":586,"startDateStruct":588,"completionDateStruct":590,"leadSponsor":592,"locationsCount":83},"100610952","the-effect-of-material-choice-on-clinical-outcomes-in-deep-margin-elevation-100610952","NCT07234266","The Effect of Material Choice on Clinical Outcomes in Deep Margin Elevation","Effect of Restorative Material Selection on Periodontal and Clinical Success in Teeth Restored With Indirect Restorations Fabricated by Additive Manufacturing After Deep Margin Elevation: A One-Year Clinical Follow-Up Study","Inclusion Criteria:\n\n* Patients who apply to Mersin University Faculty of Dentistry between 01.12.2025 and 01.03.2026 for restorative treatment of their teeth\n* Patients aged between 18 and 84 years\n* Patients without parafunctional habits (such as bruxism, clenching, or foreign object chewing)\n* Vital or non-vital molar and premolar teeth with a clinical indication for inlay\u002Fonlay restoration\n* Teeth with deep cavities and margins located at or slightly below the gingival level\n* Defects limited to the occlusal surface and one proximal surface\n* Occlusal defects extending beyond one-third of the distance between fissure and cusp tip, including at least one cusp\n* Posterior teeth with an indication for deep margin elevation without violation of the biologic width\n* Teeth with opposing natural teeth or fixed prosthetic restorations\n* Teeth with the presence of adjacent proximal contacts\n\nExclusion Criteria:\n\n* Teeth with fractures or cracks\n* Patients with temporomandibular joint disorders\n* Patients with malocclusion, bruxism, or parafunctional habits\n* Posterior teeth without opposing natural teeth or fixed prosthetic restorations\n* Posterior teeth without adjacent proximal contacts\n* Patients with a history of allergy to the components of the restorative materials used\n* Patients with severe gingival enlargement, gingival recession, or active periodontal disease\n* Teeth requiring deep margin elevation that present with non-physiological mobility, fistula, or periapical lesions","84 Years",{"count":575,"type":21},48,[61],"In dentistry, particularly in posterior teeth with extensive caries or old restorations, the extension of restoration margins below the gingival level presents a significant clinical challenge. In such cases, restorative procedures become more complicated, periodontal health may be adversely affected, and long-term tissue loss can occur. To overcome this problem, the \"Deep Margin Elevation\" technique has been developed. This approach aims to raise subgingival margins caused by caries or fractures above the gingival level, thereby providing a healthier and more favorable foundation for successful treatment.\n\nIn this study, two different materials will be used for deep margin elevation, followed by restoration of the teeth with indirect restorations fabricated using additive manufacturing technology, which has become increasingly popular in recent years. Two different additive manufacturing resins will also be applied in the restorative phase. The teeth treated with deep margin elevation and indirect restorations will be evaluated at baseline, 6 months, and 12 months according to the FDI criteria, as well as periodontal parameters due to the involvement of the gingival region.\n\nThis study aims to highlight the importance of material selection in restorative treatment planning and to scientifically demonstrate the impact of the applied technique on surrounding tissues. Furthermore, it will provide an evidence-based perspective on how adopting a tissue-friendly approach during restorative procedures may contribute to favorable long-term outcomes.",[579],"Deep Marginal Elevation",[581,582,583,584],"deep margin elevation","indirect restoration","additively manufactured","composite resin","2025-11-14",{"date":587,"type":40},"2025-11-18",{"date":589,"type":21},"2025-12-01",{"date":591,"type":21},"2026-12",{"name":46,"class":47},{"id":594,"slug":595,"hasResults":12,"nctId":596,"briefTitle":597,"officialTitle":598,"acronym":4,"eligibilityCriteria":599,"healthyVolunteers":12,"sex":17,"minAge":91,"maxAge":573,"enrollmentInfo":600,"targetDuration":4,"studyType":59,"phases":601,"briefSummary":602,"conditions":603,"keywords":605,"overallStatus":128,"whyStopped":4,"lastUpdateSubmitDate":609,"lastUpdatePostDateStruct":610,"startDateStruct":612,"completionDateStruct":614,"leadSponsor":616,"locationsCount":617},"100589873","clinical-success-of-onlays-fabricated-with-different-types-of-resin-100589873","NCT06960070","Clinical Success of Onlays Fabricated With Different Types of Resin","One-year Clinical Evaluation of Onlay Restorations Fabricated With Three Different Additive Manufacturing Resins in Endodontically Treated Teeth: A Prospective Study","Inclusion Criteria:\n\n* Molar teeth that have undergone root canal treatment\n* Teeth with proximal defects located above the gingival margin\n* Defects limited to the occlusal surface and a single adjacent surface\n* Presence of an occlusal defect extending over one-third of the distance between the fissure and the cusp tip and involving one or more cusps\n* Presence of an opposing tooth or a fixed prosthetic restoration against the tooth to be restored\n* Presence of adjacent teeth next to the tooth to be restored\n\nExclusion Criteria:\n\n* Fractured or cracked teeth\n* Patients with temporomandibular joint disorders\n* Patients with bruxism (teeth grinding)\n* Molar teeth without an opposing tooth or fixed prosthetic restoration\n* Molar teeth without adjacent teeth\n* Vital teeth\n* Patients with a history of allergy to the components of the resins",{"count":575,"type":21},[61],"Additive manufacturing, also referred to as \"3D printing\" or \"rapid prototyping,\" is defined as the process of joining materials layer by layer to create an object based on 3D model data. In this method, a digital data set is first created on a computer (computer-aided design, CAD) and then transferred to a 3D printer. The designed object is produced by printing it in successive layers.\n\nIn contrast, in subtractive manufacturing, restorations are produced by milling homogeneous blocks based on computer-designed models. Compared to subtractive manufacturing technology, additive manufacturing allows for the production of more complex, detailed, and larger structures with much less material waste and without excessive use of force.\n\nIt is thought that additive manufacturing has the potential to overcome the disadvantages of subtractive manufacturing. Over the past decade, global sales of industrial and personal 3D printers, materials, and services have increased by more than 33% annually.\n\nDue to its success in the production of surgical guides, temporary and permanent restorations, crowns and bridges, occlusal splints, frameworks, and orthodontic appliances, this technology has attracted significant interest in the field of dentistry.\n\nAlthough additive manufacturing has started to be used as an alternative to subtractive manufacturing in many applications, there is still a lack of information regarding the chemical composition, mechanical, and physical properties of printable resins. Moreover, clinical data on the use of these resins in permanent restorations are quite limited.\n\nTherefore, the aim of this study is to clinically evaluate and monitor for one year the performance of onlay restorations fabricated with three different resins of varying compositions in endodontically treated teeth.",[604],"Endodontically-Treated Teeth",[606,607,582,583,608],"onlay","endodontically -reated teeth","hybrid resin","2025-09-09",{"date":611,"type":40},"2025-09-10",{"date":613,"type":40},"2025-06-18",{"date":615,"type":21},"2027-06-18",{"name":46,"class":47},2,{"id":619,"slug":620,"hasResults":12,"nctId":621,"briefTitle":622,"officialTitle":623,"acronym":4,"eligibilityCriteria":624,"healthyVolunteers":12,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":625,"targetDuration":4,"studyType":59,"phases":626,"briefSummary":627,"conditions":628,"keywords":630,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":635,"lastUpdatePostDateStruct":636,"startDateStruct":638,"completionDateStruct":640,"leadSponsor":642,"locationsCount":83},"100605368","the-effect-of-masks-on-surgical-smoke-exposure-100605368","NCT07161609","The Effect of Masks on Surgical Smoke Exposure","The Effect of Different Types of Masks on Surgical Smoke Exposure","Inclusion Criteria:\n\n* Use of electrocautery,\n* Duration of surgery longer than 2 hours,\n* Elective total or partial hip prosthesis procedures.\n\nExclusion Criteria:\n\n* No use of electrocautery,\n* Duration of surgery shorter than 2 hours,\n* Emergency total or partial hip prosthesis procedures.",{"count":443,"type":21},[61],"Surgical smoke refers to the gaseous plume released into the air as a result of the thermal destruction of tissues by energy-based devices used in operating rooms. The composition of surgical smoke may include various organic compounds. In the literature, the most frequently identified chemical substances in surgical smoke are formaldehyde, acrolein, hydrocarbons, fatty acids, hydrocyanic acid, phenols, nitriles, acrylonitrile, hydrogen cyanide, benzene, and toluene. These particles can negatively affect the health of the operating room personnel. According to current guidelines, masks are recommended as the primary personal protective equipment to prevent respiratory exposure associated with surgical smoke. During surgical procedures, operating room staff frequently use surgical masks. Although surgical masks are the most commonly preferred personal protective equipment to protect healthcare workers against microorganisms and aerosols, they are unfortunately ineffective in filtering small particles. Therefore, the present study aimed to determine the impact of different types of masks on exposure to surgical smoke.",[629],"Surgical Smoke",[631,632,633,634],"Surgical smoke","Particle","Mask","Operating room team","2025-09-05",{"date":637,"type":40},"2025-09-08",{"date":639,"type":21},"2025-10-15",{"date":641,"type":21},"2026-04-30",{"name":46,"class":47},{"id":644,"slug":645,"hasResults":12,"nctId":646,"briefTitle":647,"officialTitle":647,"acronym":648,"eligibilityCriteria":649,"healthyVolunteers":12,"sex":172,"minAge":91,"maxAge":4,"enrollmentInfo":650,"targetDuration":4,"studyType":59,"phases":652,"briefSummary":653,"conditions":654,"keywords":657,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":661,"lastUpdatePostDateStruct":662,"startDateStruct":664,"completionDateStruct":666,"leadSponsor":668,"locationsCount":4},"100603061","the-effect-of-cryocompression-on-peripheral-neuropathy-in-patients-receiving-chemotherapy-for-gynecological-cancer-100603061","NCT07131618","The Effect of Cryocompression on Peripheral Neuropathy in Patients Receiving Chemotherapy for Gynecological Cancer","CryoPN","Inclusion Criteria:\n\n* Applying to Mersin University Hospital Oncology Outpatient Clinic\n* Willing to participate and providing signed informed consent\n* Able to read and write in Turkish\n* Accessible and able to communicate\n* Citizen of the Republic of Türkiye\n* Diagnosed with gynecologic cancer (ovarian, endometrial, or cervical) and aged ≥18 years\n* Receiving weekly carboplatin + paclitaxel chemotherapy protocol\n* No subjective peripheral neuropathy symptoms before starting chemotherapy\n* No history of peripheral neuropathy related to previous taxane\u002Fplatinum-based chemotherapy protocols\n* No psychiatric disorders\n* No diseases that may cause peripheral neuropathy such as diabetes, rheumatoid arthritis, or fibromyalgia\n\nExclusion Criteria:\n\n* Not applying to the specified outpatient clinic\n* No gynecologic cancer diagnosis or younger than 18 years old\n* Not providing informed consent\n* Not receiving weekly carboplatin + paclitaxel chemotherapy protocol\n* Presence of subjective peripheral neuropathy symptoms before starting chemotherapy\n* History of peripheral neuropathy related to previous taxane\u002Fplatinum-based chemotherapy protocols\n* Presence of psychiatric disorders\n* Having diseases that may cause peripheral neuropathy such as diabetes, rheumatoid arthritis, or fibromyalgia",{"count":651,"type":21},78,[61],"Study Design:\n\nThis study is designed as a prospective, randomized controlled experimental study aiming to determine the effect of cryocompression therapy, applied during chemotherapy, on peripheral neuropathy symptoms in women with gynecologic cancers.\n\nResearch Hypotheses:\n\n* H₀: Cryocompression therapy has no effect on peripheral neuropathy.\n* H₁: Cryocompression therapy has an effect on peripheral neuropathy.\n\nStudy Population:\n\nThe study population will consist of women over the age of 18 living in Mersin, Türkiye, who are diagnosed with gynecologic cancer and undergoing chemotherapy between August 10 and December 31, 2025.",[655,656],"Gynecological Cancers","Peripheral Neuropathy Due to Chemotherapy",[658,659,660],"Gynecological cancer","cryocompression","peripheral neuropathy","2025-08-12",{"date":663,"type":40},"2025-08-20",{"date":665,"type":21},"2025-08-10",{"date":667,"type":21},"2025-12-31",{"name":46,"class":47},{"id":670,"slug":671,"hasResults":12,"nctId":672,"briefTitle":673,"officialTitle":674,"acronym":4,"eligibilityCriteria":675,"healthyVolunteers":171,"sex":17,"minAge":91,"maxAge":4,"enrollmentInfo":676,"targetDuration":4,"studyType":59,"phases":677,"briefSummary":678,"conditions":679,"keywords":681,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":686,"lastUpdatePostDateStruct":687,"startDateStruct":689,"completionDateStruct":691,"leadSponsor":693,"locationsCount":4},"100600284","clinical-psychosocial-and-comfort-effects-of-hybrid-education-in-hemodialysis-patients-a-randomized-controlled-trial-100600284","NCT07095491","Clinical, Psychosocial, and Comfort Effects of Hybrid Education in Hemodialysis Patients: A Randomized Controlled Trial","Multidimensional Effectiveness of Self-care and Self-efficacy Based Hybrid Education in Hemodialysis Patients: A Randomised Controlled Trial on Clinical, Psychosocial and Comfort Aspects","Inclusion Criteria:\n\n* Individuals aged 18 and over\n* Patients who have been receiving hemodialysis treatment for at least 6 months\n* Those with stable clinical findings\n* Those who have not previously received professional training in self-care and self-sufficiency\n* Those who have the cognitive ability to complete the data collection form\n* Those who do not have a severe visual or auditory impairment\n* Those who can use a smartphone and have access to the WhatsApp application\n* Those who volunteer to participate in the study and sign the Informed Consent Form will be included.\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Patients receiving hemodialysis treatment for less than 6 months\n* Those whose clinical findings fluctuate to the point of being life-threatening\n* Those who have previously received professional training on self-care and self-sufficiency\n* Individuals who declare that they will not be able to attend at least one of the training sessions during the program\n* Individuals who are simultaneously participating in another training program or psychosocial intervention\n* Those who do not have the cognitive capacity to complete the data collection form\n* Individuals who cannot effectively participate in the applications due to visual or hearing impairments\n* Individuals who cannot use a smartphone or do not have access to the WhatsApp application\n* Those who do not wish to participate in the study and who do not sign the Informed Consent Form will not be included.",{"count":651,"type":21},[61],"The purpose of this study is to evaluate the impact of a self-care and self-efficacy-based hybrid education program implemented for individuals receiving hemodialysis treatment on their clinical findings, psychosocial status (dialysis distress), and comfort levels during the dialysis process.\n\nFor this purpose, the most important questions to be answered in the study are as follows:\n\n* What are the clinical findings, psychosocial status (dialysis distress), and comfort levels of hemodialysis patients at the beginning of the study?\n* Does the self-care and self-efficacy-based hybrid education have an impact on the clinical findings, psychosocial status (dialysis distress), and comfort levels of hemodialysis patients?\n\nParticipants:\n\nThe intervention group will receive a structured hybrid education program based on self-care and self-efficacy. The control group will not receive any intervention during this period and will continue with routine nursing care (standard treatment).",[680],"Interventional",[682,683,684,685],"Hemodialysis","Hybrid Education","Randomized Controlled Trial","Nursing","2025-07-24",{"date":688,"type":40},"2025-07-31",{"date":690,"type":21},"2025-08",{"date":692,"type":21},"2025-11",{"name":46,"class":47},""]