[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Milap Sandhu\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":69},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100649852","dose-optimization-study-of-acute-intermittent-hypoxia-in-spinal-cord-injury-100649852",false,"NCT07739992","Dose Optimization Study of Acute Intermittent Hypoxia in Spinal Cord Injury","Dose-Optimization Study of Acute Intermittent Hypoxia (DOSA-SCI): Effects on Lower-Limb Motor Function and Physiological Responsiveness in Individuals With Incomplete Spinal Cord Injury","DOSA-SCI","Inclusion Criteria:\n\n* Chronic Spinal Cord Injury (\\>6 months)\n* Motor incomplete SCI classified as AIS C or D\n* Volitional ankle plantarflexion strength in at least one leg\n\nExclusion Criteria:\n\n* Uncontrolled hypertension (outside 140\u002F90 and 90\u002F60)\n* Concurrent medical illness\n* Traumatic brain injury\n* Cardiovascular complications\n* Pulmonary complications\n* Metabolic dysfunction\n* Continued use of anti-spasticity medications\n* Previously diagnosed obstructive sleep apnea","ALL","18 Years","75 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to evaluate how different doses of acute intermittent hypoxia (AIH) affect lower-limb strength, reaction time, and responsiveness in individuals with spinal cord injury (SCI). The objective is to identify the dose that most effectively improves motor output while also examining parameters that may account for variability in response.",[28],"Spinal Cord Injuries (SCI)",[30,31,32],"spinal cord injury","incomplete","Acute Intermittent Hypoxia","RECRUITING","2026-07-28",{"date":36,"type":37},"2026-07-31","ACTUAL",{"date":39,"type":37},"2026-07-27",{"date":41,"type":22},"2028-07",{"name":43,"class":44},"Milap Sandhu","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":19,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":5},"100529673","promoting-recovery-outcomes-through-precise-early-locomotor-interventions-in-persons-with-spinal-cord-injury-100529673","NCT06176833","Promoting Recovery Outcomes Through Precise Early Locomotor Interventions in Persons With Spinal Cord Injury","Critical Time Window for Rehabilitation After Incomplete Spinal Cord Injury: Early vs Late Locomotor Training","PROPEL-SCI","Inclusion Criteria:\n\n* History of Acute and Traumatic SCI with AIS classification of B, C, or D between the neurological levels of C5 and T12\n* Between the ages of 16-74\n* Weight bearing as tolerated in bilateral lower extremities\n* Able to tolerate a harness\n* Ability to provide informed consent. For minors, consent of parents or primary caregivers\u002Fguardians and assent of the minor\n* Able to provide informed consent within 60 days of injury onset\n* Able to participate in all study related activities, including 1-year follow up\n\nExclusion Criteria:\n\n* Orthopedic injuries, fractures, surgeries, or other conditions affecting locomotor function or weight bearing\n* A weight over 250lbs and if so a BMI greater than 30, or deemed clinically inappropriate due to body habitus\n* Moderate to sever traumatic brain injury of other neurological conditions at a severity which impairs cognition\n* Presence of uncontrolled orthostatic hypotension that limits active participation in intense physical rehabilitation program.\n* Other medical complications such as severe heart failure or large\u002Fdeep pelvic or lower abdominal wounds that may limit the ability to safely don and doff a harness for ambulation\n* Pregnancy, as confirmed by blood draw","16 Years",{"count":56,"type":22},108,[25],"The purpose of this study is to evaluate if a specific type of additional walking therapy, called body weight supported treadmill training (BWSTT) affects walking ability following a traumatic spinal cord injury. Specifically, the study will look at whether starting BWSTT, which uses a body harness to support body weight while walking on a treadmill at different times within the first 6 months after the injury, makes a difference in how effective this therapy may be, While we know that the brain re-learns patterns following an injury, there has not been a lot of prior research evaluating how starting this type of walking therapy at specific times within the first 6 months after injury may impact any effectiveness of the additional therapy.\n\nThe study will randomize participants into four groups: those who start this therapy within 60 days, within 3 months, within 6 months or who do not receive this additional research therapy. Randomization means that which group you will be in as part of this study is determined by chance, like the flip of a coin. The additional walking therapy for this research study, if you are randomized for one of the three groups who receives the additional therapy, will be given on top of (meaning in addition to) any standard of care therapies that you may be receiving at that time point after your injury.",[60],"Spinal Cord Injuries","2026-07-01",{"date":63,"type":37},"2026-07-06",{"date":65,"type":37},"2024-03-21",{"date":67,"type":22},"2029-12",{"name":43,"class":44},""]