[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Mohammed Mahmoud Abed\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100657696","histological-and-histomorphometric-assessment-with-inflammatory-profile-analysis-of-bone-tissue-after-horizontal-ridge-augmentation-using-customized-porous-zirconia-shell-100657696",false,"NCT07841158","Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell","Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation of the Lower Posterior Mandible Using a Novel Customized Porous Zirconia Shell Technique: Clinical Case Study","Inclusion Criteria:\n\n* Age more than 21 years old\n* Horizontal bone loss in the lower posterior area (Seibert Class I)\n* Enough inter-arch space for placement of implant-supported prosthesis\n* Motivated patient to have the treatment\n* Good oral hygiene\n\nExclusion Criteria:\n\n* Patients with systemic conditions that could interfere with the healing process\n* Pregnant females\n* Smokers\n* Poor oral hygiene","ALL","21 Years",{"count":19,"type":20},10,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical study is to learn whether a custom-made porous zirconia shell can support good-quality new bone when widening the lower back jaw before dental implant placement. The study includes adults whose jawbone in this area is too narrow for implants (Seibert Class I defects).\n\nThe main question it aims to answer is: What is the quality of the new bone formed under a porous zirconia shell, and how much inflammation does the tissue show?\n\nParticipants will:\n\n* Receive gum treatment and a CBCT scan before surgery\n* Have bone augmentation surgery, in which a digitally designed porous zirconia shell is fixed over a mixture of their own bone and xenograft\n* Return after 2 weeks for suture removal and a check of the wound\n* Return after 6 months for a CBCT scan, removal of the shell, collection of a small bone sample (biopsy), and dental implant placement",[26,27],"Alveolar Bone Loss","Alveolar Ridge Deficiency",[29,30,31,32,33,34,35],"Zirconia shell","Horizontal ridge augmentation","Guided bone regeneration","Histomorphometry","Posterior mandible","Dental implants","Histology","RECRUITING","2026-09-26",{"date":39,"type":40},"2026-09-30","ACTUAL",{"date":42,"type":40},"2025-03-15",{"date":44,"type":20},"2027-07-01",{"name":46,"class":47},"Mohammed Mahmoud Abed","OTHER",""]