[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"National Hepatology & Tropical Medicine Research Institute\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":99},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,73],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100651130","phase-4-the-efficacy-of-lactobacillous-probiotic-and-trace-elements-in-the-management-of-ulcerative-colitis-patients-the-patient-will-be-recruited-from-outpatient-clinic-of-ibd-and-gastroenterology-of-the-national-hepatology-and-tropical-medicine-research-institute-nhtmri-cairo-egypt-100651130",false,"NCT07758335","The Efficacy of Lactobacillous Probiotic and Trace Elements in the Management of Ulcerative Colitis Patients the Patients Will be Recruited From Outpatient Clinic of Inflammatory Bowel Disease (IBD) of the National Hepatology and Tropical Medicine Research Institute NHTMRI, Cairo, Egypt","The Efficacy of Lactobacillous Probiotic and Trace Elements in the Management of Ulcerative Colitis Patients","Inclusion Criteria:\n\n1. Age 18-65 years.\n2. Patients diagnosed with mild to moderate UC (according to Mayo Score (36) for Ulcerative Colitis).\n3. Patients are on standard of care (biological therapy e.g., infliximab ).\n\nExclusion Criteria:\n\n1. Patients with neurological problems including Alzheimer disease and other dementias, multiple sclerosis, Parkinson's disease, history of large stroke, severe psychiatric disease as it may affect their ability to adhere to their medication and the clinical trial rules and their ability to perform the tests and questionnaires involved in the study (37).\n2. Patients with communication problems, that can affect their ability to fully understand the purpose of the trial, difficulty in communicating by phone or ability to come in scheduled visits (38).\n3. Patients with autoimmune diseases.\n4. Patients with colorectal cancer.\n5. Patients previously received probiotics or trace elements in the previous month before recruitment.\n6. Liver cirrhosis.\n7. Chronic kidney disease (CKD) which is defined as an estimated glomerular filtration rate (eGFR) less than 60 ml\u002Fmin per 1.73 m2, persisting for 3 months or more (39).\n8. Pregnancy or Lactation (40)\n9. Patients on conventional therapy (5-amino salicylic acid treatment).","ALL","18 Years","65 Years",{"count":20,"type":21},132,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","the goal of this interventional observational study is to To evaluate the efficacy , safety of lactobacillus probiotics or trace elements when added to (ulcerative colitis) infliximab in maintaining remission in UC patients and to To compare the efficacy of adding lactobacillus probiotics versus adding trace elements to infliximab This study will be open label, parallel, prospective interventional study which will be conducted in the outpatient clinic of IBD and gastroenterology of the National Hepatology and tropical medicine research institute (NHTMRI), Cairo, Egypt.\n\nThe recruited patients will be randomly allocated in one of three groups:\n\nGroup I. Study group 1 will receive 20 billion colony forming unit (CFU) of Lactobacillus acidophilus for six months together with infliximab for 6 months Group II. Study group 2 will receive 1 tablet twice daily of trace elements as Vitayami together infliximab fpr six months Group III. Control group will receive infliximab only without receiving lactobacillus or trace elements.\n\nPrimary outcome The decline in the mayo score to less than 50% after six months compared to baseline.\n\nSecondary outcome The improvement in mucosal healing after six months of intervention measured by colonoscopy compared to baseline.\n\nphysical examination will be done at the baseline then every 2 weeks of the study lab tests will be performed at base line then every 3 months intestinal ultrasound , Colonoscope will be done twice at the beginning and at the end of trial the patients also will be asked to report any adverse events every 2 weeks quality of life of patients will be assed 3 times during trial by Short Irritable Bowel Disease Questionnaire (SIBDQ) , food frequency questionnaire will be done once at the beginning of the study",[27],"Ulcerative Colitis (UC)",[29],"ulcerative colitis, remission , lactobacillus, trace elements","RECRUITING","2026-08-18",{"date":33,"type":34},"2026-08-20","ACTUAL",{"date":36,"type":34},"2025-07-02",{"date":38,"type":21},"2027-06-01",{"name":40,"class":41},"National Hepatology & Tropical Medicine Research Institute","OTHER_GOV",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":51,"targetDuration":53,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":42},"100620524","standard-two-day-advanced-life-support-als-versus-one-day-recertification-course-100620524","NCT07358741","Standard Two-Day Advanced Life Support (ALS) Versus One Day Recertification Course","Balancing Time and Outcomes: A Prospective Observational Study Comparing the Effectiveness of the Standard Two-Day Advanced Life Support (ALS) Versus One Day Recertification Course","Inclusion Criteria:\n\n* Adult healthcare professionals (≥18 years) requiring ALS recertification, including doctors, nurses, and paramedics, who can attend the assigned course and follow-up assessments.\n\nExclusion Criteria:\n\n* Participants will be excluded if they cannot attend the assigned course or decline consent.",true,{"count":52,"type":21},158,"90 Days","OBSERVATIONAL","this study aims to compare the effectiveness of a one-day versus two-day ALS recertification course in terms of knowledge retention, practical skills performance, participant satisfaction, and confidence.",[57,58],"Skill Performance","Knowledge",[60,61,62,63,64],"Standard","recertification","ALS","ERC","knowledge retention","2026-01-15",{"date":67,"type":34},"2026-01-22",{"date":69,"type":34},"2025-12-12",{"date":71,"type":21},"2026-11-30",{"name":40,"class":41},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":50,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},"100599541","assessment-of-cardiopumonary-resuscitation-cpr-competency-post-als-course-100599541","NCT07085832","Assessment of Cardiopumonary Resuscitation (CPR) Competency Post ALS Course","Assessment of Cardiopumonary Resuscitation (CPR) Competency Among Healthcare Providers at the End of Advanced Life Support Training Course in Egypt","Inclusion Criteria:\n\n* Providers who will complete an ALS training course (two day-course).\n\nExclusion Criteria:\n\n* Providers who will not complete ALS training course, those with physical limitations preventing effective chest compressions. Providers who will take immediate life support course (one day course), candidates attend from other courses to attend missed session and candidates who arrive late and cannot join the pre-course assessment.","70 Years",{"count":82,"type":21},300,[84],"NA","to assess chest compression competency in healthcare providers following ALS training to identify areas for improvement and ensure high-quality CPR delivery.",[87],"Chestcompressionadequacy",[89],"CPR, metrics","2025-07-18",{"date":92,"type":34},"2025-07-25",{"date":94,"type":34},"2025-06-01",{"date":96,"type":21},"2026-06-01",{"name":40,"class":41},2,""]