[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"National Institute of Unani Medicine, Bengaluru\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":54},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":5},"100657575","phase-2-comparative-study-on-unani-formulation-vs-active-control-in-plaque-psoriasis-100657575",false,"NCT07841314","Comparative Study on Unani Formulation Vs Active Control in Plaque Psoriasis","Comparative Study on Marham-e-Asfedaj Versus Coal Tar 1% and Salicylic Acid 3% Solution Along With Mundij wa Mushil-i Sawdā in Taqashshur-al- Jild (Plaque Psoriasis) - A Randomized Open Labelled, Split Body Active Control Clinical Trial","Inclusion Criteria:\n\n* Subjects of all gender identities aged 20-60 years\n* k\u002Fc\u002Fo Subjects suffering with chronic Plaque Psoriasis\n* New subjects clinically and histopathologically diagnosed with Plaque Psoriasis\n* Subjects having PASI score: 3-20 and SPI-s \\\u003C20\n* Subjects with Symmetrical Plaque Psoriasis lesions\n* Willing to consent for all trial requirements\n\nExclusion Criteria:\n\n* Subjects with severe Plaque Psoriasis PASI \\>20 and SPI-severe (SPI-s \\>21)\n* Subjects with any superadded infected Psoriasis\n* Subjects having Psoriatic Arthritis and ocular psoriasis.\n* Subjects suffering from other diseases and on concomitant therapy and drugs that can aggravate Psoriasis like Beta blockers, Calcium Channel Blockers or Lithium.\n* Subjects with h\u002Fo alcohol \\& drug abuse\n* Pregnant and lactating women\n* Subjects with other inflammatory skin conditions in the treatment area (eg.tinea corporis, contact dermatitis, atopic dermatitis)\n* Subjects taking or requiring corticosteroids\n* K\u002Fc\u002Fo subjects with Current or past history of hepatic or renal insufficiency","ALL","20 Years","60 Years",{"count":20,"type":21},54,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","This trial tests whether a Unani ointment (Marham-e-Asfedaj) plus an oral Unani formulation (Mundij wa Mushil-i Sawdā) works better than a active treatment (salicylic acid 3% solution, also combined with Mundij wa Mushil-i Sawdā) for treating chronic plaque psoriasis in adults. It will also check whether Marham-e-Asfedaj is safe to use.\n\nMain question: Does adding Marham-e-Asfedaj to Mundij wa Mushil-i Sawdā work better than adding salicylic acid 3% solution to Mundij wa Mushil-i Sawdā?\n\nWhat participants will do:\n\n* Take a Unani oral medicine (Mundij wa Mushil-i Sawdā) once a day for the first 40 days\n* Have two matching psoriasis patches treated differently - one side of the body (chosen at random) gets a Unani ointment (Marham-i-Asfedaj), and the other side gets a standard treatment (coal tar 1% + salicylic acid 3%). Both are applied twice daily from day 1 to day 60\n* Give blood samples to check general health, liver, and kidney function, and have a small skin sample taken (biopsy) at the start (day 0) and end of treatment to see how the histological morphology has changed\n* Come in for check-ups on days 0, 15, 30, 45, and 60, with a final follow-up visit one month after treatment ends\n* Not use any other psoriasis treatment during the study, so the results reflect only the study treatments\n\nTrial duration: 60 days of treatment, plus a follow-up visit 1 month later - so each participant is involved for about 3 months total.\n\nWhat the study is measuring (outcome measures):\n\n* Severity of psoriasis, tracked using two standard scoring tools (PASI and SPI), checked five times during treatment\n* Quality of life, using a standard skin-disease questionnaire (DLQI), checked at the same visits\n* Skin changes under the microscope, comparing biopsy samples from before and after treatment\n* Safety, through blood tests checking overall health, liver, and kidney function",[27,28,29,30],"Chronic Plaque Psoriasis","Plaque Psoriasis","Psoriasis","Taqashshur al Jild",[32,30,33,34,35,36,37,38,39,40,41],"Plaque psoriasis","Histology","Dermatology","Marham Asfedaj","Mundiz wa mushil Sawda","purgative therapy","Unani medicine","Unani Formulation","Unani formulation in Plaque psoriasis","Marham Asfedaj in plaque psoriasis","NOT_YET_RECRUITING","2026-09-19",{"date":45,"type":46},"2026-09-25","ACTUAL",{"date":48,"type":21},"2027-04-01",{"date":50,"type":21},"2029-05-01",{"name":52,"class":53},"National Institute of Unani Medicine, Bengaluru","OTHER",""]