[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"National Nutrition and Food Technology Institute\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":45,"locationsCount":4},"100654644","comparing-two-low-carbohydrate-diets-with-a-standard-diet-in-type-2-diabetes-100654644",false,"NCT07801378","Comparing Two Low-Carbohydrate Diets With a Standard Diet in Type 2 Diabetes","Comparison of Two Moderate Low-Carbohydrate Diets (High-Protein and High-Fat) Versus a Standard Diet on Metabolic Indices in Patients With Type 2 Diabetes, Hypertriglyceridemia, and Overweight or Obesity: A Three-Arm Randomized Clinical Trial","Inclusion Criteria:\n\n* Diagnosed with type 2 diabetes mellitus for at least 6 months\n* Fasting serum triglycerides between 200-399 mg\u002FdL\n* Body mass index (BMI) between 25 and 35 kg\u002Fm\\^2\n* Age between 30 and 70 years\n* If taking medication for diabetes, dyslipidemia, or hypertension, dose stable for at least 8 weeks prior to enrollment\n* Able to follow the prescribed diet\n* Willing and able to provide informed consent\n\nExclusion Criteria:\n\n* Fasting triglycerides of 400 mg\u002FdL or higher, or lower than 200 mg\u002FdL\n* HbA1c greater than 10.5%\n* eGFR less than 30 mL\u002Fmin\u002F1.73m\\^2\n* Type 1 diabetes or rare metabolic disorders\n* Severe renal, cardiac, or hepatic disease, or active pancreatitis\n* Established cardiovascular disease (myocardial infarction, stroke, coronary angioplasty or bypass surgery, or heart failure)\n* Pregnancy, breastfeeding, or planning pregnancy during the study\n* Psychiatric disorder or social circumstances that would prevent adherence to the dietary protocol\n* Change in dose or type of diabetes, lipid-lowering, or blood pressure medication within 8 weeks before enrollment or during the study\n* Use of weight-loss medications, protein supplements, or probiotics\n* Body weight change greater than 3% within the past 6 months\n* Withdrawal of consent to continue participation","ALL","30 Years","70 Years",{"count":20,"type":21},168,"ESTIMATED","INTERVENTIONAL",[24],"NA","Type 2 diabetes is often accompanied by high blood triglycerides and excess weight, and diet plays a central role in managing these conditions together. The purpose of this study is to compare the effects of two moderate low-carbohydrate diets - one higher in protein and one higher in fat - against a standard diet, on blood sugar control, blood lipids (especially triglycerides), body weight, and blood pressure in adults with type 2 diabetes, hypertriglyceridemia, and overweight or obesity.",[27,28,29],"Diabete Mellitus","Obesity & Overweight","Hypertriglyceridaemia",[31,32,33,34,35,36],"low_carbohydrate diet","type 2 diabetes","T2D","Obesity","metabolic indexes","hypertriglyceridaemia","NOT_YET_RECRUITING","2026-09-04",{"date":40,"type":41},"2026-09-08","ACTUAL",{"date":43,"type":21},"2026-09-20",{"date":43,"type":21},{"name":46,"class":47},"National Nutrition and Food Technology Institute","OTHER",""]