[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"National Research Center for Rehabilitation Technical Aids\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":131},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,40,65,89,110],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100651988","ai-based-dysphagia-rehabilitation-program-development-and-validation-100651988",false,"NCT07767123","AI-Based Dysphagia Rehabilitation Program: Development and Validation","Development and Validation of an Artificial Intelligence-Based Rehabilitation Program for Dysphagia","Inclusion Criteria:\n\n1. Age ≥ 18 years;\n2. Diagnosed with dysphagia, confirmed by clinical screening (e.g., abnormal Water Swallow Test) or instrumental assessment (e.g., FEES);\n3. Conscious and alert, without severe cognitive impairment, and capable of understanding instructions and cooperating with swallowing function assessments and rehabilitation therapy;\n4. Provision of informed consent, with the informed consent form signed by the patient or their legal representative.\n\nExclusion Criteria:\n\n1. Age \\\u003C 18 years;\n2. Presence of impaired consciousness, coma, or severe cognitive impairment, rendering the patient unable to understand instructions or cooperate with assessments and treatments;\n3. Presence of severe psychiatric disorders, behavioral abnormalities, or severe aphasia\u002Fhearing impairment, preventing cooperation with swallowing function assessment and therapy;\n4. Presence of severe anatomical abnormalities of the upper respiratory or digestive tract (e.g., laryngeal\u002Fesophageal tumors, recent major head and neck surgery), which contraindicate FEES or conventional swallowing therapy;\n5. Medically unstable conditions (e.g., severe respiratory distress, hemodynamic instability, acute infection phase), rendering the patient unable to tolerate assessments or rehabilitation therapy;\n6. Temporary dysphagia caused by acute, reversible factors (e.g., acute alcohol or drug intoxication);\n7. Any other conditions deemed by the investigator as inappropriate for participation in this study.",true,"ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical study is to learn if an artificial intelligence (AI)-assisted swallowing rehabilitation program can improve swallowing function in adults with dysphagia. It will also learn whether this approach can better detect aspiration (food or liquid entering the airway) and improve eating ability. The main questions it aims to answer are:\n\nCan AI-assisted analysis help identify swallowing treatment parameters that improve swallowing right away?\n\nDoes an optimized AI-assisted swallowing treatment work better than standard treatment parameters over 6 weeks?\n\nCan AI using data from sensors detect aspiration accurately?\n\nResearchers will compare swallowing function before and after treatment. They will also compare optimized treatment parameters selected with AI and FEES (a camera-based swallowing test) with standard treatment parameters. In addition, researchers will compare AI model results with FEES findings to see how well the sensors can identify aspiration.\n\nParticipants will:\n\nComplete swallowing assessments, including FEES, drinking tests, and swallowing questionnaires.\n\nHave small sensors placed to record muscle activity, sound, oxygen levels, and breathing while swallowing.\n\nReceive swallowing rehabilitation over 6 weeks, with treatment given in 1-week periods. During each period, treatment will be randomly assigned as either optimized parameters or standard parameters.\n\nComplete swallowing assessments after treatment periods to measure changes in swallowing function and eating ability.",[27],"Dysphagia","NOT_YET_RECRUITING","2026-08-16",{"date":31,"type":32},"2026-08-19","ACTUAL",{"date":34,"type":21},"2026-08",{"date":36,"type":21},"2027-12",{"name":38,"class":39},"National Research Center for Rehabilitation Technical Aids","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":16,"sex":17,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":4},"100652009","developing-and-testing-an-ai-based-cognitive-intervention-program-100652009","NCT07766993","Developing and Testing an AI-Based Cognitive Intervention Program","Research and Validation of an Artificial Intelligence-Based Cognitive Intervention Program","AICog","Inclusion Criteria:\n\n1. Chinese community-dwelling residents aged ≥ 40 years;\n2. Cognitive function adequate to cooperate with testing and interventions;\n3. No history of major neurological or psychiatric disorders;\n4. Not on long-term use of medications known to affect cognitive function significantly ;\n5. Possess the basic access and ability to use smartphones or the internet to receive online interventions;\n6. Good compliance, with the expected ability to adhere to and complete a 1-year follow-up.\n\nExclusion Criteria:\n\n1. Age \\\u003C 40 years;\n2. Cognitive function inadequate to cooperate with testing and interventions;\n3. History of major neurological disorders (e.g., stroke, Parkinson's disease, brain tumors, epilepsy) or severe psychiatric disorders (e.g., schizophrenia, severe depressive episodes);\n4. Currently taking medications known to significantly affect cognitive function (e.g., anticholinergic drugs, certain psychotropic medications);\n5. Presence of severe systemic or physical illnesses (e.g., advanced malignancy, severe heart, lung, liver, or kidney failure);\n6. Lack of access to smartphones or the internet, rendering the participant unable to receive online interventions;\n7. Any other conditions deemed by the investigator as inappropriate for participation in this study.","40 Years",{"count":50,"type":21},100,[24],"The goal of this clinical study is to learn if an artificial intelligence (AI)-assisted lifestyle intervention program can help protect memory and thinking skills in adults aged 40 years and older who do not have severe cognitive impairment. It will also learn whether the program can help people maintain healthier lifestyle habits and whether it affects blood markers related to Alzheimer's disease. The main questions it aims to answer are:\n\nCan the AI-assisted program help participants improve their lifestyle, including diet, exercise, mental activities, social participation, sleep, smoking, alcohol use, and stress? Does a healthier lifestyle help maintain memory and thinking skills over 1 year? Are healthier lifestyle habits related to changes in blood markers such as p-tau217, which may be related to Alzheimer's disease? Does the effect differ for people who carry the APOE ε4 gene, a gene that may increase the risk of Alzheimer's disease? Researchers will compare participants with healthier lifestyles to those with less healthy lifestyles, to see whether healthier lifestyles are linked to better memory and thinking and different blood marker levels.\n\nParticipants will:\n\nJoin an online lifestyle intervention program for 1 year. Receive personalized advice about diet, exercise, mental activities, and social participation through an online platform, WeChat tools, an AI assistant, and online messages.\n\nComplete memory and thinking tests and lifestyle questionnaires at the start of the study, at 6 months, and at 12 months.\n\nGive blood samples at the start of the study and at 12 months for tests related to Alzheimer's disease.\n\nHave APOE gene testing at the start of the study.",[54,55,56],"Intact Cognitive Function","MCI","Mild Dementia","2026-08-14",{"date":59,"type":32},"2026-08-18",{"date":61,"type":21},"2026-11-01",{"date":63,"type":21},"2027-12-31",{"name":38,"class":39},{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":4,"eligibilityCriteria":70,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":71,"targetDuration":4,"studyType":22,"phases":72,"briefSummary":73,"conditions":74,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},"100440407","neural-mechanisms-of-cognitive-assessment-and-rehabilitation-for-cognitive-decline-100440407","NCT05014893","Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive Decline","Inclusion Criteria:\n\n* Adults being able to walk at least a block, and\n* Adults with subjective cognitive decline (SCD), or\n* Adults with mild cognitive impairment (MCI), or\n* Adults with normal cognitive function\n\nExclusion Criteria:\n\n* Clinical diagnosis of dementia\n* Adults who cannot follow the protocal",{"count":50,"type":21},[24],"This study investigates the neural mechanisms of cognitive function decline, cognitive assessment methods for subjects with mild cognitive dysfunction (Mild cognitive impairment, MCI, or cognitive decline milder than MCI), and the approaches used to improve and restore cognitive function.",[75,76,77,78],"Mild Cognitive Impairment (MCI)","Subjective Cognitive Decline (SCD)","Aging","Healthy","RECRUITING","2025-05-20",{"date":82,"type":32},"2025-05-22",{"date":84,"type":32},"2021-08-06",{"date":86,"type":21},"2026-12-31",{"name":38,"class":39},1,{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":95,"eligibilityCriteria":96,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":97,"enrollmentInfo":98,"targetDuration":4,"studyType":22,"phases":100,"briefSummary":101,"conditions":102,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":104,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":108,"locationsCount":109},"100361078","fall-prevention-in-elderly-mechanisms-and-strategies-100361078","NCT03981471","Fall Prevention in Elderly: Mechanisms and Strategies","STrategies and mechAnisms of Community-Based falL Prevention in Elderly","STABLE","Inclusion Criteria:\n\n* community dwelling adults without medical conditions to impair walking ability\n\nExclusion Criteria:\n\n* cognitively or physically unable to cooperate with the examiner to finish the test","85 Years",{"count":99,"type":21},4000,[24],"In communities with over 100,000 residents, to investigate the incidence and mechanisms of fall in elderly, and strategies of fall prevention.",[103],"Elderly",{"date":82,"type":32},{"date":106,"type":32},"2019-06-03",{"date":86,"type":21},{"name":38,"class":39},2,{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":117,"enrollmentInfo":118,"targetDuration":4,"studyType":120,"phases":4,"briefSummary":121,"conditions":122,"keywords":4,"overallStatus":79,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":130,"locationsCount":88},"100360906","developing-effectiveness-evaluation-and-therapeutic-programs-of-rehabilitation-100360906","NCT03979235","Developing Effectiveness Evaluation and Therapeutic Programs of Rehabilitation","Developing Clinic-oriented Quantitative Effectiveness Evaluation and Individualized Therapeutic Programs of Rehabilitation","Inclusion Criteria (for healthy people):\n\n* no history of psychological\u002Fpsychotic problems, no history of important diseases.\n\nExclusion Criteria (for healthy people):\n\n* history of psychological\u002Fpsychotic problems\n\nInclusion Criteria (for patients with motor deficits or dysphagia):\n\n* patients with motor function impairment such as post stroke hemiplegia.\n\nExclusion Criteria (for patients with motor deficits or dysphagia):\n\n* cognitively or physically unable to cooperate with the examiner to finish the test","80 Years",{"count":119,"type":21},40,"OBSERVATIONAL","Using robotics, sensors, and sEMG to develop clinic-oriented quantitative effectiveness evaluation and individualized programs of rehabilitation",[123,124,27],"Healthy Volunteers","Motor Deficits",{"date":126,"type":32},"2025-05-23",{"date":128,"type":32},"2019-06-05",{"date":86,"type":21},{"name":38,"class":39},""]