[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"National Yang Ming Chiao Tung University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":606},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,43,0,25,[9,50,78,99,126,150,170,187,213,233,253,272,298,322,351,367,388,410,430,447,475,500,529,556,581],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100651414","smart-nursing-ai-agent-for-health-self-management-100651414",false,"NCT07761663","Smart Nursing AI Agent for Health Self-Management","Smart Nursing AI Agent for Health Self-Management Among Middle-aged and Older Adults","Inclusion Criteria:\n\n1. Patients aged 50 years or older who present with mobility limitations such as gait instability, sarcopenia, joint degeneration, chronic pain, or functional decline\n2. Able to ambulate\n3. Alert and oriented\n\nExclusion Criteria:\n\n1. Terminal cancer or major illness with a prognosis of left 6 months\n2. Moderate to severe dementia or language expression disorders\n3. Individuals with significant audiovisual impairments that prevent AI conversation\n4. Unable to complete walking tests on their own","ALL","50 Years",{"count":20,"type":21},102,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to develop and evaluate a smart nursing AI agent to support health self-management among middle-aged and older patients, and further to examine its effectiveness in home care and health self-management. The goal is to propose innovative strategies for middle-aged and older care that enhance the quality of home care and strengthen patients' health self-management abilities. A randomized controlled trial design will be adopted, with a planned enrollment of 102 participants. Participants will be randomly assigned to either the experimental group or the control group. Regardless of group assignment, their routine medical care will remain unchanged. Both groups will participate in the study for 12 weeks (8 weeks of intervention and 4 weeks of follow-up), with identical frequency and number of follow-ups, interviews, and evaluations. The experimental group will receive an 8 week intervention using the smart nursing AI agent care model, which provides daily interaction, reminder systems, personalized recommendations, activity monitoring, goal setting, motivational support, and health self-management education. The control group will continue with the existing standard health education approach. Data collection will include demographic information, medical history, physiological indicators, functional activity measures (e.g., steps, distance, exercise duration), sarcopenia screening, nutritional assessment, physical activity levels, health self-management ability, health literacy, quality of life, and digital usage behaviors. Statistical analyses will be conducted to evaluate the effectiveness, feasibility, and acceptability of the intervention.",[27,28,29],"Mobility Limitations","Community-dwelling Older Adults","Middle-aged and Older Adults",[31,32,33,34,35,36],"Health Self-Management","Smart Nursing AI Agent","eHealth Literacy","community-dwelling older adults","Middle-aged and older adults","mobility limitations","NOT_YET_RECRUITING","2026-08-09",{"date":40,"type":41},"2026-08-12","ACTUAL",{"date":43,"type":21},"2026-08-05",{"date":45,"type":21},"2028-08-05",{"name":47,"class":48},"National Yang Ming Chiao Tung University","OTHER",1,{"id":51,"slug":52,"hasResults":12,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":49},"100649393","vestibular-balance-cognition-dual-task-digital-system-development-of-a-smart-rehabilitation-platform-for-the-elderly-and-prediction-of-balance-function-risks-100649393","NCT07735078","Vestibular Balance-Cognition Dual-Task Digital System: Development of a Smart Rehabilitation Platform for the Elderly and Prediction of Balance Function Risks","Inclusion Criteria:\n\n1. Community-dwelling adults aged 55 years or older.\n2. Able to walk at least 30 meters independently or with the use of a walking aid.\n3. Able to understand the study procedures and communicate in Mandarin or Taiwanese.\n4. Adequate corrected vision to go out independently.\n5. Able to participate in 45-minute sessions of moderate-intensity exercise once per week.\n\nExclusion Criteria:\n\n1. Severe central or peripheral neurological diseases.\n2. Blindness or deafness.\n3. Inability to communicate verbally or to understand simple instructions.\n4. Current fractures or major joint injuries.",true,"55 Years",{"count":59,"type":21},55,"OBSERVATIONAL","This study is being done to better understand how vestibular problems and thinking abilities (such as attention and mental flexibility) are related in older adults, and how doing a balance task and a thinking task at the same time affects their performance. Older adults will first complete questionnaires and simple paper-and-pencil tests of attention, memory, and mental rotation while seated. They will then perform standing balance tasks on a portable force platform under different conditions (eyes open, eyes closed, standing on a foam surface) and will repeat some of the thinking tasks at the same time. Next, participants will walk on a treadmill while wearing small motion sensors, both with and without added thinking tasks such as serial subtraction and digit reordering. The total testing time is about 90 minutes. Two groups will be included: healthy older adults and older adults who have had dizziness or falls in the past two years. By comparing these groups, the study aims to provide a basis for designing future dual-task assessment and training programs to reduce balance problems and falls in older adults.",[63,64,65,66,67,68],"Vestibular Dysfunction","Dizziness","Falls (Accidents) in Old Age","Balance Assessment","Cognitive Function Decline","Dual-Task Performance","RECRUITING","2026-07-26",{"date":72,"type":41},"2026-07-29",{"date":74,"type":41},"2025-02-10",{"date":76,"type":21},"2027-03-11",{"name":47,"class":48},{"id":79,"slug":80,"hasResults":12,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":56,"sex":17,"minAge":85,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":49},"100645489","smart-facial-exercise-coaching-system-for-older-adults-100645489","NCT07700654","Smart Facial Exercise Coaching System for Older Adults","Development and Testing of a Smart Facial Coaching System for Older Adults","Inclusion Criteria:\n\n* Willing to participate in this study voluntarily.\n* Able to provide written informed consent.\n* Aged 60 years or older.\n* Able to communicate in Mandarin Chinese or Taiwanese.\n\nExclusion Criteria:\n\n* Severe visual or hearing impairment.\n* Diagnosis of moderate to severe dementia.\n* Inability to communicate verbally.\n* Presence of obvious structural or pathological lesions of the face.\n* Diseases or conditions affecting swallowing function (e.g., stroke).","60 Years",{"count":87,"type":21},130,[24],"Participants will participate in a 5-day facial exercise program and will be assessed at baseline, immediately after completion of the intervention, and 1 month after completion of the intervention.\n\nOlder adults aged 60 years and above who are able to communicate in Mandarin or Taiwanese and who participate in activities at adult day-care centers or community care centers will be eligible for inclusion. Individuals with severe visual or hearing impairment, moderate to severe dementia, inability to communicate verbally, obvious facial wounds or lesions, or medical conditions affecting swallowing function (e.g., stroke) will be excluded from participation.\n\nA total of approximately 130 participants will be recruited and assigned to one of two groups:\n\nIntervention Group (n ≈ 65): Participants will perform facial exercises using the Smart Facial Coaching System.\n\nControl Group (n ≈ 65): Participants will perform facial exercises by following a video-based facial exercise program.\n\nAfter providing informed consent and meeting the eligibility criteria, participants will complete baseline assessments, including structured questionnaires and the Repetitive Saliva Swallowing Test (RSST).\n\nParticipants in both groups will then perform facial exercises for five consecutive days, with each session lasting approximately 10-15 minutes.\n\nUpon completion of the 5-day facial exercise program, participants will complete post-intervention assessments, including structured questionnaires and the Repetitive Saliva Swallowing Test (RSST).\n\nOne month after completion of the intervention, participants will complete follow-up questionnaires assessing facial exercise behavior and psychosocial outcomes, which will take approximately 15-20 minutes.",[91],"Aging",{"date":93,"type":41},"2026-07-28",{"date":95,"type":21},"2026-07-20",{"date":97,"type":21},"2027-05-21",{"name":47,"class":48},{"id":100,"slug":101,"hasResults":12,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":22,"phases":109,"briefSummary":110,"conditions":111,"keywords":113,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":4},"100647419","healing-stigma-through-stories-100647419","NCT07708402","Healing Stigma Through Stories","Healing Stigma Through Stories: Learning From International Practices to Develop and Evaluate a Narrative Program for Individuals With Schizophrenia","Inclusion Criteria:\n\n* Aged 18 years or older.\n* Diagnosed with schizophrenia or schizoaffective disorder.\n* Clinically stable at the time of study enrollment.\n* Able to communicate in Mandarin Chinese or Taiwanese.\n* Able to read and write and complete study questionnaires.\n\nExclusion Criteria:\n\n* Individuals who lack the capacity to provide informed consent. Decision-making capacity will be assessed using a 10-item true\u002Ffalse questionnaire adapted from Okoli et al. (2018). Participants who answer fewer than 7 questions correctly will be excluded. Those who answer 7 or more questions correctly will receive an additional explanation from the research team. Only individuals who demonstrate a complete understanding of the study after this explanation will be enrolled.\n* Unwilling to have the intervention sessions audio-recorded.","18 Years",{"count":108,"type":21},24,[24],"This study is the first phase of the research project. The purpose of this phase is to develop and refine a narrative-based intervention designed to reduce self-stigma among people with schizophrenia.\n\nA small pilot study will be conducted with 24 participants recruited from halfway houses in northern Taiwan. Eligible participants will receive the intervention, which consists of four group sessions and four individual sessions, held once a week for a total of eight weeks. The program uses narrative therapy techniques to help participants explore their personal experiences and reduce self-stigma. Participants will complete a workbook during the program, and the written content will be analyzed to better understand their experiences with stigma. Any personal information will be removed to protect participants' privacy. Before and after the intervention, participants will complete questionnaires on self-stigma, depression, social functioning, well-being, hope, and recovery. Information on medication use will also be collected. Group and individual sessions will be audio-recorded for research purposes. The questionnaire data and recordings will be used to evaluate the feasibility and preliminary effects of the intervention.",[112],"Schizophrenia \u002F Schizoaffective Disorder",[114,115,116,117],"schizophrenia","mix-method study","self-stigma","narrative therapy","2026-07-10",{"date":120,"type":41},"2026-07-16",{"date":122,"type":21},"2026-08-01",{"date":124,"type":21},"2027-07",{"name":47,"class":48},{"id":127,"slug":128,"hasResults":12,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":4,"eligibilityCriteria":132,"healthyVolunteers":56,"sex":17,"minAge":106,"maxAge":133,"enrollmentInfo":134,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":136,"conditions":137,"keywords":139,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":49},"100646812","alterations-in-spiking-following-muscle-fatigue-in-volleyball-players-100646812","NCT07687550","Alterations in Spiking Following Muscle Fatigue in Volleyball Players","Alterations in Spiking Kinematic, Muscle Activation, and Subacromial Structures Following Muscle Fatigue in Volleyball Players","Inclusion Criteria:\n\n* Between 18 and 35 years old\n* At least 2 consecutive years of volleyball experience\n* Involved in volleyball practice or game for at least 4 hours per week\n* Able to perform a cross-body spike with 3-step\n\nExclusion Criteria:\n\n* A history of major shoulder or spinal injury or surgery\n* Experiencing shoulder pain (VAS ≥ 3\u002F10) in the last 6 months","35 Years",{"count":135,"type":21},35,"This study aims (1)to investigate the effects of repetitive functional overhead movements targeting shoulder and scapular muscles on glenohumeral and scapular kinematics and muscle activation during the arm cocking and acceleration of spiking, and changes in subacromial structures in healthy recreational volleyball players; (2) to compare these fatigue-related changes between athletes with good and poor shoulder motor control.",[138],"Fatigue",[138,140,141],"Athlete","Volleyball","2026-07-01",{"date":144,"type":41},"2026-07-07",{"date":146,"type":21},"2026-07",{"date":148,"type":21},"2027-01",{"name":47,"class":48},{"id":151,"slug":152,"hasResults":12,"nctId":153,"briefTitle":154,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":56,"sex":17,"minAge":106,"maxAge":156,"enrollmentInfo":157,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":49},"100642755","the-effect-of-unstable-loads-on-scapular-kinematics-and-muscle-activation-during-overhead-press-in-overhead-athletes-with-subacromial-pain-syndrome-100642755","NCT07646899","The Effect of Unstable Loads on Scapular Kinematics and Muscle Activation During Overhead Press in Overhead Athletes With Subacromial Pain Syndrome","The inclusion criteria for both the experimental and control groups were as follows: (1) amateur or recreational overhead athletes aged 18-40 years (e.g., volleyball, tennis, baseball); (2) sport participation history of more than 3 years; (3) weekly overhead sport participation of more than 4 hours; (4) ability to meet the minimum loading requirements of the equipment for both stable and unstable conditions, defined as a 15-repetition maximum (15RM) for stable shoulder press of ≥10 kg and unstable shoulder press of ≥8 kg.\n\nThe individual inclusion criteria for the experimental group were: (1) diagnosis of subacromial pain syndrome, defined as at least 3 positive findings out of 5 clinical tests (Painful Arc test, Neer impingement test, Empty Can test, Hawkins-Kennedy impingement test, and Resisted External Rotation test); (2) Visual Analogue Scale (VAS) score of ≤3 during shoulder press performance; (3) symptoms present on the dominant side.\n\nThe individual inclusion criteria for the control group were: absence of shoulder pain within the past 6 months, including no pain at the glenohumeral joint, acromioclavicular joint, sternoclavicular joint, scapulothoracic joint, or cervical spine.\n\nThe exclusion criteria were as follows: (1) history of surgical intervention for fracture or dislocation of the shoulder or elbow joint within the past 6 months; (2) direct trauma to the cervical spine or upper extremity within the past 1 month; (3) shoulder pain or neurological symptoms of cervical origin; (4) any condition preventing the completion of the experimental protocol; (5) bilateral shoulder pain.","40 Years",{"count":158,"type":21},27,"The research aims to compare the differences between stable and unstable load conditions during shoulder pressing in overhead athletes with SAPS and to compare the differences between SAPS and healthy athletes with stable and unstable load conditions.",[161],"Subacromial Pain Syndrome","2026-06-09",{"date":164,"type":41},"2026-06-15",{"date":166,"type":41},"2024-09-26",{"date":168,"type":21},"2026-06-30",{"name":47,"class":48},{"id":171,"slug":172,"hasResults":12,"nctId":173,"briefTitle":174,"officialTitle":174,"acronym":4,"eligibilityCriteria":175,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":85,"enrollmentInfo":176,"targetDuration":4,"studyType":22,"phases":178,"briefSummary":179,"conditions":180,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":182,"startDateStruct":183,"completionDateStruct":184,"leadSponsor":186,"locationsCount":4},"100642381","effects-of-cervical-manual-therapy-for-temporomandibular-disorders-with-myalgia-100642381","NCT07647887","Effects of Cervical Manual Therapy for Temporomandibular Disorders With Myalgia","Inclusion Criteria:\n\n* Diagnosed with myogenous TMDs, defined as chronic myalgia (lasting \\>3 months continuously or \\> 6 months intermittently) 90 with or without accompanying arthralgia according to DC\u002FTMD criteria\n* A visual analogue scale (VAS) score of 3 or greater at baseline\n* 18 to 60 years of age\n\nExclusion Criteria:\n\n* Diagnosed with disc displacement without reduction or degenerative joint disease according to the DC\u002FTMD criteria\n* A diagnosis of systemic diseases such as fibromyalgia, rheumatoid arthritis, systemic erythematous lupus, or psoriatic arthritis\n* A diagnosis of neurological disorders (e.g., trigeminal neuralgia, cervical radiculopathy, or myelopathy)\n* Evidence of central nervous system involvement (positive pathological reflexes)\n* A history of traumatic injuries (e.g., contusion, fracture, or whiplash injury) in the last 6 weeks\n* Signs of vertebral artery insufficiency or upper cervical instability revealed by physical examination\n* Receiving cervical spine mobilization or manipulation or acupuncture for their TMDs within the last 1 week\n* any contraindication to TMS",{"count":177,"type":21},48,[24],"Background: Temporomandibular disorders (TMDs) are the leading cause of non-odontogenic orofacial pain interfering with daily activities. TMDs consist of a group of conditions affecting the masticatory muscles, the temporomandibular joint (TMJ), or the associated structures. Previous studies showed alterations in TMJ kinematics, cortical excitability, electromyographic (EMG) activity of the masticatory muscles, and tongue pressure in individuals with TMDs compared to healthy controls. Furthermore, several studies have demonstrated that manual therapy applied to the cervical joint could reduce pain and improve jaw function in individuals with TMDs. However, the effects of upper cervical mobilization on TMJ kinematics, cortical excitability, tongue pressure, and EMG of masticatory muscles during mouth opening in individuals with myogenous TMDs remain unknown.\n\nPurpose: This study aims to investigate the immediate effects of upper cervical mobilization on TMJ kinematics, EMG of masticatory system muscles, cortical excitability, and tongue pressure in individuals with myogenous TMDs.\n\nMethods: A randomized controlled trial will be conducted with a total sample size of 48 participants. Individuals diagnosed with myogenous TMDs, defined as chronic myalgia (lasting \\>3 months continuously or \\> 6 months intermittently) according to the Diagnostic Criteria for Temporomandibular Disorders, will be recruited for this study. Participants will be randomly assigned to either the experimental or the control group, stratified by age and sex. The experimental group will receive a single session of upper cervical mobilization, while the control group will receive a placebo maneuver. The primary outcomes will include TMJ kinematics and EMG activity of the masseter and suprahyoid muscles, while the secondary outcomes will include cortical excitability, tongue pressure, pain intensity, and upper cervical mobility. All measurements will be taken before and immediately after the intervention.\n\nStatistical analysis: The continuous and categorical variables of clinical and demographic characteristics will be analyzed by an independent t test\u002FMann-Whitney U test and a Chi-square test, respectively. A 2×2 mixed-model analysis of variance (ANOVA) will be used to analyze the outcome measures and to test the main effects and interactions between time and group. If there is a significant interaction effect, post hoc pairwise comparisons with Bonferroni correction will be used. The alpha level is set at 0.05.",[181],"Temporomandibular Disorders (TMDs)",{"date":164,"type":41},{"date":142,"type":21},{"date":185,"type":21},"2027-12-31",{"name":47,"class":48},{"id":188,"slug":189,"hasResults":12,"nctId":190,"briefTitle":191,"officialTitle":191,"acronym":4,"eligibilityCriteria":192,"healthyVolunteers":56,"sex":17,"minAge":106,"maxAge":4,"enrollmentInfo":193,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":195,"conditions":196,"keywords":199,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":205,"lastUpdatePostDateStruct":206,"startDateStruct":208,"completionDateStruct":210,"leadSponsor":212,"locationsCount":49},"100627455","kinematics-and-muscle-activation-of-scapula-in-upper-string-players-with-neck-pain-100627455","NCT07448857","Kinematics and Muscle Activation of Scapula in Upper String Players With Neck Pain","Inclusion Criteria:\n\n* Age ≥ 18 years old.\n* Having at least 5 years of string instrument playing experience and practicing for more than 6 hours per week.\n* For the neck pain group: Experiencing non-specific neck pain for at least 2 weeks, with pain located between the superior nuchal line and the T1 spinous process, and a pain intensity of at least 3 on the Numeric Rating Scale (NRS ≥ 3).\n* For the healthy control group: Having no history of neck or shoulder pain within the past year (matched with the neck pain group by age, gender, and handedness).\n\nExclusion Criteria:\n\n* History of any neck or shoulder surgery or fracture.\n* Experiencing pain below the elbow with an intensity of at least 3 (NRS ≥ 3).\n* Diagnosed history of any structural cervical spine issues, such as herniation of intervertebral disc (HIVD), cervical spine spondylosis, or spondylolisthesis.\n* Positive response on any of the following 5 cervical spine screening tests: cervical distraction test, Spurling's test, Valsalva test, rotational alar ligament stress test, or Sharp-Purser test.\n* Any neurological disorders.\n* Pregnancy during the study period.",{"count":194,"type":21},60,"This study will analyze and compare scapular kinematics and muscle activation patterns between upper string musicians with and without neck pain during arm elevation and playing tasks (open strings, scales, musical pieces), providing insights for performance training and rehabilitation programs to reduce playing-related musculoskeletal disorders.",[197,198],"Non-specific Neck Pain","Playing Related Musculoskeletal Disorders",[200,201,202,203,204,198],"Non-specific neck pain","upper string musicians","scapular kinematics","muscle activity","shoulder electromyography","2026-05-11",{"date":207,"type":41},"2026-05-14",{"date":209,"type":41},"2026-05-10",{"date":211,"type":21},"2026-12-31",{"name":47,"class":48},{"id":214,"slug":215,"hasResults":12,"nctId":216,"briefTitle":217,"officialTitle":217,"acronym":4,"eligibilityCriteria":218,"healthyVolunteers":56,"sex":17,"minAge":106,"maxAge":156,"enrollmentInfo":219,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":220,"conditions":221,"keywords":223,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":225,"lastUpdatePostDateStruct":226,"startDateStruct":228,"completionDateStruct":230,"leadSponsor":232,"locationsCount":49},"100634730","kinematics-and-muscle-activity-during-the-tennis-serve-and-musculoskeletal-characteristics-in-tennis-players-with-subacromial-pain-syndrome-or-history-of-shoulder-pain-100634730","NCT07543484","Kinematics and Muscle Activity During the Tennis Serve and Musculoskeletal Characteristics in Tennis Players With Subacromial Pain Syndrome or History of Shoulder Pain","Inclusion Criteria:\n\n* Amateur tennis players\n* National Tennis Rating Program (NTRP) should level ≥ 3.5\n* Training experience: ≥ 3 years, current or former school team players\n* Training volume: ≥ 4 hours\u002Fweek\n\nExclusion Criteria:\n\n* Any current musculoskeletal injuries preventing maximum skill execution at the time of testing\n* Previously had any form of surgery or trauma\n* Patient-reported pain that will inhibit participation in this study",{"count":194,"type":21},"Tennis players often suffer from shoulder pain due to the repetitive high-loaded overhead movements during serving, and subacromial pain syndrome is one of the main types of shoulder pain. Previous shoulder injury has been identified as one of the risk factors for shoulder overuse injuries in overhead sports. No research has explored differences in trunk kinematics and shoulder muscle activities among tennis players with and without subacromial pain syndrome or a history of shoulder pain. Furthermore, limited studies have examined shoulder kinematics during tennis serve and musculoskeletal characteristics in tennis players with subacromial pain syndrome or a history of shoulder pain. Therefore, this study aims to investigate shoulder and trunk kinematics and shoulder muscle activity during the tennis serve and musculoskeletal characteristics in tennis players with subacromial pain syndrome or a history of shoulder pain. This study will recruit sixty tennis players with subacromial pain syndrome, a history of shoulder pain, and healthy players. The electromagnetic tracking system will be applied to collect shoulder and trunk kinematics during the tennis serve, and surface electromyography will be simultaneously used for recording shoulder muscle activities. Moreover, we will collect shoulder and trunk rotational joint range of motion, isometric strength and rate of force development of shoulder internal and external rotation, scapulothoracic and glenohumeral joint control capability, upper quarter Y-balance test performance, and posterior shoulder endurance. This study will compare the difference of these measures in tennis players with subacromial pain syndrome or a history of shoulder pain to healthy players.",[222],"Shoulder Pain",[224],"shoulder pain, tennis, kinematics, electromyography","2026-04-15",{"date":227,"type":41},"2026-04-22",{"date":229,"type":41},"2026-01-29",{"date":231,"type":21},"2027-01-29",{"name":47,"class":48},{"id":234,"slug":235,"hasResults":12,"nctId":236,"briefTitle":237,"officialTitle":237,"acronym":4,"eligibilityCriteria":238,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":4,"enrollmentInfo":239,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":240,"conditions":241,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":225,"lastUpdatePostDateStruct":246,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":4},"100634709","effectiveness-of-laser-acupuncture-in-improving-arterial-stiffness-among-patients-with-cardiorenal-metabolic-syndrome-100634709","NCT07543211","Effectiveness of Laser Acupuncture in Improving Arterial Stiffness Among Patients With Cardiorenal Metabolic Syndrome","Inclusion Criteria:\n\n1. Age 18 years or older\n2. Diagnosed with at least two conditions related to cardio-renal-metabolic syndrome (e.g., hypertension, diabetes mellitus, chronic kidney disease, or dyslipidemia)\n3. Receiving routine laser acupuncture treatment in a clinical setting\n4. Able to understand the study procedures and provide informed consent\n\nExclusion Criteria:\n\n1. Presence of acute cardiovascular events (e.g., acute myocardial infarction, stroke)\n2. Acute kidney injury\n3. Presence of medical devices or conditions that contraindicate the use of laser acupuncture at the treatment site (e.g., arteriovenous shunt)\n4. Unable to complete the study procedures or follow-up assessments",{"count":135,"type":21},"Background: Cardio-renal metabolic syndrome (CRMS) is a vicious cycle of cardiac, renal, and metabolic disease, representing a high-risk for atherosclerosis. Laser acupuncture modulates vascular inflammation and improves endothelial function via low-level laser therapy (LLLT, \\\u003C500mW) at acupoints or musculoskeletal pain sites. Few studies have focused on CRMS populations. This study evaluates laser acupuncture effects on arterial stiffness in CRMS.\n\nPurpose: To assess the effects of improvement of laser acupuncture in patients with CRMS, and to evaluate its feasibility as supportive therapy.\n\nMethods: A single-group pre-post design is used. Participants are patients with CRMS receiving laser acupuncture at a Chinese medicine clinic in Taiwan. CRMS is interrelated by cardiac, renal, and metabolic disease. Inclusion criteria require diagnosis in ≥2 of 3 systems (cardiovascular, renal, or metabolic; n = 35). Laser acupuncture will be applied to bilateral BL40 for 12 weeks (1-3 sessions\u002Fweek, 60mins\u002Fsession). Pulse wave velocity(PWV) measured by Omron HBP- 8000 as the primary outcome for arterial stiffness. Paired t-tests and GEE will be used for analysis.\n\nExpected Results: PWV is expected to show significant improvement after intervention.",[242,243,244,245],"Hypertension","Diabetes Mellitus","Chronic Kidney Disease","Cardio-Renal-Metabolic Syndrome",{"date":247,"type":41},"2026-04-21",{"date":249,"type":21},"2026-05",{"date":251,"type":21},"2026-10",{"name":47,"class":48},{"id":254,"slug":255,"hasResults":12,"nctId":256,"briefTitle":257,"officialTitle":257,"acronym":4,"eligibilityCriteria":258,"healthyVolunteers":56,"sex":17,"minAge":106,"maxAge":18,"enrollmentInfo":259,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":261,"conditions":262,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":264,"lastUpdatePostDateStruct":265,"startDateStruct":267,"completionDateStruct":269,"leadSponsor":271,"locationsCount":49},"100552381","structure-and-function-of-the-upper-trapezius-and-its-role-in-chronic-shoulder-pain-an-investigation-of-kinematics-morphology-muscle-quality-and-activation-distribution-100552381","NCT06472349","Structure and Function of the Upper Trapezius and Its Role in Chronic Shoulder Pain: an Investigation of Kinematics, Morphology, Muscle Quality and Activation Distribution","Inclusion Criteria:\n\n* Chronic shoulder pain group\n\n  * 18-50 years old18-50 years old\n  * unilateral and non-traumatic shoulder pain\n  * pain duration longer than 3 months\n  * pain intensity more than VAS=2 during movement\n  * presence 3 of 5 positive pain provocation tests: Hawkins-Kennedy test, Jobe test, or Neer's test Painful Arc, and Resistance Test against External Rotation.\n* Healthy control group\n\n  * presenting no shoulder pain at rest or during daily activities\n  * negative results of the pain provocation test: Hawkins-Kennedy test, Jobe test, Neer's test, Painful Arc, Resistance Test against External Rotation and Spurling's neck compression test.\n\nExclusion Criteria:\n\n\\- Chronic shoulder pain group\n\n* history of significant shoulder trauma, such as fracture or ultrasonography clinically suspected full thickness cuff tear\n* recent shoulder dislocation in the last 2 years\n* diagnosis of adhesive capsulitis characterized by a gradual and painful loss of both active and passive ROM in all shoulder planes, primarily external rotation\n* shoulder pain originating from the cervical spine by using Spurling's neck compression test\n* shoulder pain owing to the following disorders: arthritis (e.g., rheumatoid arthritis, osteoarthritis of shoulder complex), neurologic (e.g., stroke), neoplastic (e.g., breast cancer). and\u002For referred pain (e.g., visceral referred pain)\n* corticoid injections over the shoulder during 6 months prior to the study\n* history of shoulder and neck surgery",{"count":260,"type":21},100,"Prior research has explored factors influencing muscle activation, including muscle thickness, fear avoidance beliefs (kinesiophobia), and somatosensory integration. In individuals with chronic shoulder pain, various characteristics impacting symptoms and treatment outcomes have been identified, such as psychosocial factors, fear avoidance, central sensitization, somatosensory impairments, and brain morphology changes. These shared characteristics affecting both muscle activation and chronic shoulder pain may potentially modulate upper trapezius muscle activation during functional movements in patients with chronic shoulder pain. Notably, there remains a gap in the literature concerning investigations into the upper trapezius muscle's morphology and quality, fear avoidance, central sensitization, somatosensory impairments, and their interplay with upper trapezius muscle activation in chronic shoulder pain patients.\n\nTo address these gaps, this study aims to: this study aims to: 1) compare different methods of measuring clavicular kinematics using an electromagnetic tracking system; 2) establish the reliability and validity of measuring muscle thickness and fat infiltration through ultrasound and magnetic resonance imaging; 3) compare shoulder kinematics, muscle activation, muscle morphology, and muscle fat infiltration in individuals with chronic shoulder pain with matched healthy controls; 4) explore the correlation between the factors that may influence upper trapezius muscle activation, including basic data of the subjects, muscle morphology, and muscle fat infiltration.",[263],"Chronic Shoulder Pain","2026-04-09",{"date":266,"type":41},"2026-04-14",{"date":268,"type":41},"2023-12-12",{"date":270,"type":21},"2026-12",{"name":47,"class":48},{"id":273,"slug":274,"hasResults":12,"nctId":275,"briefTitle":276,"officialTitle":277,"acronym":278,"eligibilityCriteria":279,"healthyVolunteers":56,"sex":17,"minAge":280,"maxAge":106,"enrollmentInfo":281,"targetDuration":4,"studyType":22,"phases":283,"briefSummary":284,"conditions":285,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":289,"lastUpdatePostDateStruct":290,"startDateStruct":292,"completionDateStruct":294,"leadSponsor":296,"locationsCount":297},"100586859","multi-modal-digital-interventions-for-adolescent-weight-management-100586859","NCT06920862","Multi-Modal Digital Interventions for Adolescent Weight Management","Effectiveness of Multi-Modal Digital Interventions for Adolescent Weight Management: A Randomized Controlled Trial","M2DI-AWM","Inclusion Criteria:\n\n* Adolescents aged 12-18 years.\n* Body Mass Index (BMI) ≥ 85th percentile according to the Health Promotion Administration (HPA) standards.\n* Willing to participate in a digital intervention for weight control.\n* At least one parent or guardian provides consent for participation.\n* Able to understand and use digital devices (smartphones, tablets, or computers).\n\nExclusion Criteria:\n\n* Significant communication barriers (e.g., severe speech, hearing, or cognitive impairments).\n* Psychiatric disorders that affect interpersonal interaction (e.g., schizophrenia, severe depression).\n* Previous negative experiences with digital health interventions (VR or AI-based coaching).\n* Severe motion sickness that affects the ability to use VR-based tools.\n* Currently enrolled in another weight management program that may interfere with study outcomes.","12 Years",{"count":282,"type":21},200,[24],"The goal of this randomized controlled trial is to evaluate the effectiveness of a multi-modal digital intervention, based on the Theory of Planned Behavior (TPB), in promoting healthy weight control behaviors among overweight and obese adolescents. This study also aims to reduce the risk of unhealthy weight control behaviors by leveraging artificial intelligence-driven coaching, interactive platforms, gamified applications, and real-time feedback mechanisms.\n\nThe main questions this study aims to answer are:\n\n1. Can a multi-modal digital intervention effectively modify adolescents' primary beliefs underlying TPB constructs (attitude, subjective norms, and perceived behavioral control)?\n2. How do TPB constructs influence weight control intentions, and how do these intentions translate into either healthy or unhealthy weight control behaviors? What role do adolescents' body image, body satisfaction, and mental health play in moderating the relationship between weight control intention and behavior?\n\nParticipants will:\n\n1. Be adolescents aged 12-18 years with a BMI ≥ 85th percentile.\n2. Be randomly assigned to either the intervention group (multi-modal digital intervention) or the control group (general health education).\n3. Engage in AI-driven coaching, interactive digital sessions, and gamified experiences tailored to TPB constructs.\n4. Complete biweekly sessions over a period of three months (each session lasting two hours).\n5. Receive personalized feedback and real-time monitoring through the Virti platform.\n6. Participate in follow-up assessments at one month and three months post-intervention.\n\nResearchers will compare the intervention group to the control group to determine whether the multi-modal digital intervention leads to a higher adoption of healthy weight control behaviors and a lower prevalence of unhealthy weight control behaviors.",[286,287,288],"Obesity, Adolescent","Weight Change, Body","Weight Stigma","2026-04-06",{"date":291,"type":41},"2026-04-13",{"date":293,"type":41},"2025-08-01",{"date":295,"type":21},"2029-12-31",{"name":47,"class":48},2,{"id":299,"slug":300,"hasResults":12,"nctId":301,"briefTitle":302,"officialTitle":303,"acronym":4,"eligibilityCriteria":304,"healthyVolunteers":56,"sex":17,"minAge":305,"maxAge":156,"enrollmentInfo":306,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":308,"conditions":309,"keywords":311,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":315,"lastUpdatePostDateStruct":316,"startDateStruct":318,"completionDateStruct":320,"leadSponsor":321,"locationsCount":49},"100627257","motion-and-emg-analysis-of-the-forehand-topspin-forehand-stroke-and-forehand-attack-in-elite-table-tennis-players-100627257","NCT07446283","Motion and EMG Analysis of the Forehand Topspin, Forehand Stroke, and Forehand Attack in Elite Table Tennis Players","Motion and Electromyographic Analysis of the Forehand Topspin Against Topspin, Forehand Topspin Against Backspin, Forehand Stroke, and Forehand Attack in Elite Table Tennis Players","Inclusion Criteria:\n\n* The ages range from 13 to 40 years old\n* Competed in the Chinese Taipei Table Tennis Ranking Tournament or the National Table Tennis Championships within the past three years\n* At least four years of table tennis experience, and train for more than 10 hours per week\n\nExclusion Criteria:\n\n* History of upper limb surgery or fracture\n* History of shoulder dislocation\n* History of spine injury in the last year\n* Systemic autoimmune disease or cancer\n* Pregnancy\n* Any neurological complications","13 Years",{"count":307,"type":21},40,"This research will analyze and compare the muscle activation levels, muscle recruitment timing, trunk kinematics, and shoulder joint kinematics between the four forehand strokes and between elite table tennis players with and without shoulder injuries, providing insights for daily training and rehabilitation programs to reduce the occurrence of sports injuries.",[310],"Elite Table Tennis Players",[312,204,313,314],"elite table tennis players","trunk kinematics","trunk electromyography","2026-03-30",{"date":317,"type":41},"2026-04-03",{"date":319,"type":41},"2026-01-02",{"date":211,"type":21},{"name":47,"class":48},{"id":323,"slug":324,"hasResults":12,"nctId":325,"briefTitle":326,"officialTitle":327,"acronym":4,"eligibilityCriteria":328,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":329,"enrollmentInfo":330,"targetDuration":4,"studyType":22,"phases":331,"briefSummary":332,"conditions":333,"keywords":335,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":344,"startDateStruct":346,"completionDateStruct":348,"leadSponsor":350,"locationsCount":49},"100630963","vestibular-training-on-community-ambulation-and-fall-risk-in-stroke-100630963","NCT07494500","Vestibular Training on Community Ambulation and Fall Risk in Stroke","Effects of Vestibular Training on Community Ambulation and Fall Risk in Individuals With Chronic Stroke","Inclusion Criteria:\n\n* Diagnosis of First-occurrenced stroke\n* ≥ 6 months after stroke\n* Ability to walk at least 400 meters with or without the use of a walking assistive device\n* Mini-Mental State Examination score ≥ 24\n* Age between 18 and 80 years\n\nExclusion Criteria:\n\n* Other neurological or musculoskeletal conditions affected postural stability\n* Presence of dizziness or vertigo\n* Presence of conditions affecting cervical blood flow or limiting cervical range of motion\n* Visual impairment\n* Unstable cardiac status or uncontrolled hypertension","80 Years",{"count":307,"type":21},[24],"Nearly half of individuals with stroke experience limitations in community ambulation, and 35.7% of community-dwelling stroke survivors experienced falls while walking, indicating that falls are common during routine daily activities in community settings. Sensory reweighting refers to the ability to appropriately prioritize and integrate sensory inputs to maintain postural stability. Stroke survivors often demonstrate impaired sensory reweighting, characterized by excessive reliance on visual and proprioceptive cues and insufficient integration of vestibular information. This deficit adversely affects postural control and subsequently compromises gait performance and fall risk .In addition, many individuals with stroke exhibit reduced gaze stability during walking and turning, suggesting potential impairments in the vestibulo-ocular reflex (VOR), a key mechanism for maintaining stable vision during head movement. Insufficient gaze stability has been associated with gait disturbances; therefore, deficits in sensory reweighting and VOR function may contrib-ute to limited community ambulation and increased fall risk. Although previous studies have primarily focused on general balance training, few have directly targeted vestibular input. Thus, the effectiveness of vestibular-specific training for improving community ambulation and reducing fall risk in chronic stroke remains unclear. This study aims to investigate the effects of vestibular training on community ambulation and fall risk in individuals with chronic stroke.",[334],"Stroke",[336,337,338,339,340,341,342],"community ambulation","vestibular training","vestibular rehabilitation","fall risk","stroke","dynamic acuity","gait","2026-03-20",{"date":345,"type":41},"2026-03-27",{"date":347,"type":21},"2026-04-01",{"date":349,"type":21},"2028-07-31",{"name":47,"class":48},{"id":352,"slug":353,"hasResults":12,"nctId":354,"briefTitle":355,"officialTitle":356,"acronym":4,"eligibilityCriteria":328,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":329,"enrollmentInfo":357,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":359,"conditions":360,"keywords":361,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":363,"startDateStruct":364,"completionDateStruct":365,"leadSponsor":366,"locationsCount":49},"100630962","reliability-of-community-ambulation-ability-fall-risk-and-dynamic-visual-acuity-assessments-in-stroke-100630962","NCT07494487","Reliability of Community Ambulation Ability, Fall Risk, and Dynamic Visual Acuity Assessments in Stroke","Reliability of Community Ambulation Assessments, Taiwan Chinese Version of Falls Efficacy Scale, and Dynamic Visual Acuity Test in Individuals With Chronic Stroke",{"count":358,"type":21},30,"Nearly half of individuals with stroke experience limitations in community ambulation, and 35.7% of community-dwelling stroke survivors experienced falls while walking, indicating that falls are common during routine daily activities in community settings. Patla (1999) proposed that community mobility is influenced by eight factors: ambient conditions, terrain characteristics, external physical load, attentional demands, postural transitions, traffic level, time constraints, and walking distance. This framework suggests that community ambulation requires consideration of multiple physiological domains as well as environmental factors. However, current assessments of community ambulation primarily rely on indoor walking speed as an indicator, which may be insufficient to fully evaluate patients' community ambulation ability. Previous studies have not yet established the reliability of community ambulation assessments such as the Walking Ability Questionnaire, community walking speed, and the Falls Efficacy Scale (Taiwan Chinese version)-in individuals with chronic stroke. Additionally, stroke survivors often demonstrate insufficient integration of vestibular information, which may affect gait performance through impaired dynamic visual acuity. Therefore, this study aims to investigate the reliability of community ambulation assessments and dynamic visual acuity testing in individuals with chronic stroke.",[334],[339,336,340,341,362],"reliability",{"date":345,"type":41},{"date":347,"type":21},{"date":349,"type":21},{"name":47,"class":48},{"id":368,"slug":369,"hasResults":12,"nctId":370,"briefTitle":371,"officialTitle":372,"acronym":4,"eligibilityCriteria":373,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":329,"enrollmentInfo":374,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":376,"conditions":377,"keywords":379,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":383,"startDateStruct":384,"completionDateStruct":385,"leadSponsor":387,"locationsCount":297},"100630960","inhibitory-control-and-gait-adaptability-in-parkinsons-disease-100630960","NCT07494461","Inhibitory Control and Gait Adaptability in Parkinson's Disease","Relationship Between Inhibitory Control and Gait Adaptability During Obstacle Crossing in People With Parkinson's Disease","Inclusion Criteria:\n\n* A clinical diagnosis of idiopathic Parkinson's disease;\n* Stable use of prescribed antiparkinsonian medication for at least two weeks;\n* Modified Hoehn and Yahr stage I to III;\n* Age between 18 and 80 years;\n* Ability to ambulate independently for at least 30 meters without assistive devices;\n* A Mini-Mental State Examination (MMSE) score of ≥ 24;\n* Corrected vision and hearing sufficient to effectively receive external stimuli\n\nExclusion Criteria:\n\n* The presence of any neurological, musculoskeletal, or cardiovascular disorders that could affect participation in this study;\n* The presence of psychiatric disorders that could interfere with the ability to follow instructions or comply with study procedures;\n* A history of brain surgery, such as deep brain stimulation (DBS)",{"count":375,"type":21},50,"People with Parkinson's disease (PD) may have difficulty stopping or changing their movements, especially when walking around obstacles.\n\nThe goal of this observational study is to learn if a specific cognitive function, called inhibitory control (the ability to stop or control actions) is associated with gait adaptability in people with Parkinson's disease. Gait adaptability means the ability to adjust how a person walks in response to changes in the environment, such as stepping over obstacles.\n\nThe main questions the study aims to answer are:\n\n* If brain activation related to inhibitory control, measured by EEG, is associated with gait adaptability during obstacle crossing in people with Parkinson's disease?\n* If behavioral inhibitory control is associated with gait adaptability during obstacle crossing in people with Parkinson's disease?\n\nParticipants take part in one study visit. During this visit, participants complete simple thinking tests, have their brain activity recorded using EEG, and perform walking tasks that include stepping over obstacles.",[378],"Parkinson Disease (PD)",[380,381,382],"Electroencephalography","Executive function","Obstacle crossing",{"date":345,"type":41},{"date":347,"type":21},{"date":386,"type":21},"2029-08-31",{"name":47,"class":48},{"id":389,"slug":390,"hasResults":12,"nctId":391,"briefTitle":392,"officialTitle":393,"acronym":4,"eligibilityCriteria":394,"healthyVolunteers":56,"sex":17,"minAge":156,"maxAge":329,"enrollmentInfo":395,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":397,"conditions":398,"keywords":401,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":343,"lastUpdatePostDateStruct":403,"startDateStruct":405,"completionDateStruct":407,"leadSponsor":409,"locationsCount":297},"100561342","brain-activity-cognitive-function-and-walking-ability-in-parkinsons-disease-100561342","NCT06588920","Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease","Brain Activity, Cognitive Function, and Walking Ability in People With Parkinson's Disease","Inclusion Criteria:\n\n* Diagnoses of idiopathic Parkinson disease\n* Stable dopaminergic medicine ≥ 2 weeks\n* Able to walk 10 meters without aid\n* Mini-Mental Status Examination ≥ 24 points\n* No uncorrected visual or auditory disorders\n* Education at least junior high school\n* No other disease may affect balance\n\nExclusion Criteria:\n\n* Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders\n* History of brain surgery (e.g. deep brain stimulation)",{"count":396,"type":21},70,"The dual-task automated walking performance in people with Parkinson\\'s disease (PD) is affected by their gait disturbances and impaired executive functions. Currently, the relationship between brain activity related to inhibitory control, executive functions, and dual-task walking performance in people with PD is not well understood. Therefore, this study aims to investigate the significance of different executive function domains on gait stability in healthy older adults and people with PD; whether brain activation related to inhibitory control is associated with gait stability in healthy older adults and people with PD.",[399,400],"Healthy Older Adults","Parkinson Disease",[381,402,380],"Gait",{"date":404,"type":41},"2026-03-24",{"date":406,"type":41},"2024-10-09",{"date":408,"type":21},"2027-08-31",{"name":47,"class":48},{"id":411,"slug":412,"hasResults":12,"nctId":413,"briefTitle":414,"officialTitle":415,"acronym":4,"eligibilityCriteria":416,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":4,"enrollmentInfo":417,"targetDuration":4,"studyType":22,"phases":418,"briefSummary":419,"conditions":420,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":422,"lastUpdatePostDateStruct":423,"startDateStruct":425,"completionDateStruct":427,"leadSponsor":429,"locationsCount":4},"100617893","immediate-effects-of-manual-and-verbal-cueing-during-movement-control-training-in-chronic-non-specific-low-back-pain-100617893","NCT07324538","Immediate Effects of Manual and Verbal Cueing During Movement Control Training in Chronic Non-Specific Low Back Pain","A Randomized Controlled Trial Comparing the Immediate Effects of Manual and Verbal Cueing During Movement Control Training in Individuals With Chronic Non-Specific Low Back Pain","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Clinically diagnosed chronic non-specific low back pain with symptoms lasting longer than 12 weeks\n* Able to understand and comply with the assessment and intervention procedures\n\nExclusion Criteria:\n\n* History of surgery involving the lower back or lower extremities\n* Presence of neurological symptoms, such as paresthesia or numbness\n* Signs or symptoms of nerve root compression\n* History of surgery within the past 3 months\n* History of cancer\n* Presence of major medical or psychiatric disorders\n* Presence of systemic inflammatory conditions\n* Pregnancy\n* Structural scoliosis\n* Inability to walk or stand independently, or any condition deemed unsuitable for participation by the investigator\n* Participation in any movement control exercise training within the past year",{"count":307,"type":21},[24],"Chronic non-specific low back pain is commonly associated with impaired movement control. Movement control training is often used in rehabilitation, and different cueing methods may influence how patients perform and learn movements.\n\nThe purpose of this randomized controlled trial is to compare the immediate effects of manual cueing and verbal cueing during movement control training in individuals with chronic non-specific low back pain. Participants will be randomly assigned to receive either manual cueing or verbal cueing during a standardized movement training session.\n\nThe study will examine immediate changes in movement control performance, perceived difficulty, and related clinical outcomes following the intervention. The results of this study may help clinicians better understand how different cueing strategies influence movement performance in people with chronic non-specific low back pain.",[421],"Chronic Low Back Pain (Non-specific, Uncomplicated)","2026-01-22",{"date":424,"type":41},"2026-01-23",{"date":426,"type":21},"2026-03-15",{"date":428,"type":21},"2027-01-31",{"name":47,"class":48},{"id":431,"slug":432,"hasResults":12,"nctId":433,"briefTitle":434,"officialTitle":435,"acronym":4,"eligibilityCriteria":436,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":4,"enrollmentInfo":437,"targetDuration":4,"studyType":22,"phases":439,"briefSummary":440,"conditions":441,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":422,"lastUpdatePostDateStruct":442,"startDateStruct":443,"completionDateStruct":444,"leadSponsor":446,"locationsCount":4},"100617425","comparison-of-abdominal-expansion-and-abdominal-drawing-in-training-with-manual-and-verbal-cueing-in-chronic-non-specific-low-back-pain-100617425","NCT07318454","Comparison of Abdominal Expansion and Abdominal Drawing-In Training With Manual and Verbal Cueing in Chronic Non-Specific Low Back Pain","A Randomized Controlled Trial Comparing Abdominal Expansion and Abdominal Drawing-In Training With Manual and Verbal Cueing in Individuals With Chronic Non-Specific Low Back Pain","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Clinically diagnosed with chronic non-specific low back pain, with symptoms persisting for more than 12 weeks.\n* Able to understand the study procedures and comply with the full intervention and assessment protocol.\n\nExclusion Criteria:\n\n* History of surgery involving the lower back or lower extremities.\n* Presence of neurological symptoms, such as numbness or tingling sensations.\n* Signs or symptoms of nerve root compression.\n* History of any surgical procedure within the past 3 months.\n* Diagnosis of cancer.\n* Presence of major medical or psychiatric disorders.\n* Presence of systemic inflammatory disease.\n* Pregnancy.\n* Structural scoliosis of the spine.\n* Inability to ambulate or stand independently, or other conditions deemed unsuitable for participation.\n* Participation in any movement control-based exercise training within the past year.\n* Accumulated experience of more than 4 weeks of abdominal drawing-in manoeuvre (ADIM) training or Dynamic Neuromusculoskeletal Stabilization abdominal expansion (DNS-AE) training within the past year.",{"count":438,"type":21},96,[24],"This study aims to investigate the interactive effects of two core stability training strategies-abdominal drawing-in manoeuvre (ADIM) and Dynamic Neuromusculoskeletal Stabilization abdominal expansion (DNS-AE)-and two instructional approaches (verbal cueing and manual facilitation) on training outcomes in individuals with chronic non-specific low back pain.\n\nA 2×2 factorial randomized controlled trial design will be employed. Ninety-six participants with chronic non-specific low back pain will be randomly allocated, using block randomization, to one of four intervention groups in equal proportions. All groups will receive a 4-week intervention program, with training conducted twice per week.\n\nOutcome measures will be assessed at four time points: before the intervention (baseline), immediately after the first training session, at the completion of the 4-week intervention, and at a 3-month follow-up, to evaluate short-term and mid-term effects as well as the sustainability of training outcomes.",[421],{"date":424,"type":41},{"date":347,"type":21},{"date":445,"type":21},"2026-09-30",{"name":47,"class":48},{"id":448,"slug":449,"hasResults":12,"nctId":450,"briefTitle":451,"officialTitle":452,"acronym":4,"eligibilityCriteria":453,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":454,"enrollmentInfo":455,"targetDuration":4,"studyType":22,"phases":457,"briefSummary":458,"conditions":459,"keywords":461,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":468,"lastUpdatePostDateStruct":469,"startDateStruct":470,"completionDateStruct":472,"leadSponsor":474,"locationsCount":49},"100620807","comparing-myofascial-exercise-and-trigger-point-therapy-for-non-specific-low-back-pain-100620807","NCT07362420","Comparing Myofascial Exercise and Trigger Point Therapy for Non-Specific Low Back Pain","Effects of Myofascial Chain-Based Specific Exercise and Myofascial Trigger Point Therapy in People With Non-Specific Low Back Pain","Inclusion Criteria:\n\n* Adults aged 18 to 65 years\n* Nonspecific low back pain lasting longer than 6 weeks\n* Average low back pain intensity of 3 or higher on a 0-10 Numeric Pain Rating Scale\n* Presence of at least 6 myofascial trigger points identified across bilateral target muscles\n* Presence of muscle function impairments in at least 6 muscle groups based on functional muscle testing\n* Able to understand study procedures and participate in an exercise-based intervention\n* Willing and able to attend treatment sessions and complete study assessments\n\nExclusion Criteria:\n\n* Currently pregnant\n* Diagnosed spondylolisthesis or vertebral compression fracture\n* Known malignancy or history of cancer affecting the spine\n* Previous lumbar spine surgery\n* Known neurological, infectious, or systemic disease that may affect pain or movement\n* Any other medical condition that, in the opinion of the investigators, would interfere with safe participation in the study","65 Years",{"count":456,"type":21},105,[24],"The goal of this clinical trial is to learn if two common physical therapy approaches, used alone or together, can help reduce pain and improve daily function in adults with nonspecific low back pain. Nonspecific low back pain means low back pain without a clear medical cause.\n\nThe main questions this study aims to answer are:\n\n1. Does hands-on pressure to painful muscle spots (called myofascial trigger point therapy) help lower low back pain?\n2. Does a guided exercise program that focuses on how muscles work together help lower low back pain?\n3. Does combining hands-on therapy with exercise work better than using either approach alone?\n\nResearchers will compare three groups to see which approach leads to greater improvement. One group will receive hands-on trigger point therapy, one group will do a specific exercise program, and one group will receive both treatments.\n\nParticipants will:\n\n* Be assigned to one of the three treatment groups by chance\n* Receive treatment twice a week for four weeks\n* Complete simple assessments before treatment starts, after the first treatment session, and after the final session\n\nThe results of this study may help physical therapists choose better noninvasive treatment options for people with nonspecific low back pain.",[460],"Non-specific Low Back Pain",[460,462,463,464,465,466,467],"Low Back Pain","Myofascial Trigger Points","Myofascial Chain","Exercise Therapy","Manual Therapy","Physical Therapy","2026-01-15",{"date":424,"type":41},{"date":471,"type":21},"2026-01-30",{"date":473,"type":21},"2026-11-30",{"name":47,"class":48},{"id":476,"slug":477,"hasResults":12,"nctId":478,"briefTitle":479,"officialTitle":480,"acronym":4,"eligibilityCriteria":481,"healthyVolunteers":12,"sex":17,"minAge":106,"maxAge":4,"enrollmentInfo":482,"targetDuration":4,"studyType":22,"phases":483,"briefSummary":484,"conditions":485,"keywords":489,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":493,"lastUpdatePostDateStruct":494,"startDateStruct":496,"completionDateStruct":497,"leadSponsor":499,"locationsCount":49},"100620282","mobile-app-assisted-home-exercise-for-musculoskeletal-disorders-100620282","NCT07355595","Mobile App-Assisted Home Exercise for Musculoskeletal Disorders","The Effect of the Mobile App-Assisted Home Exercise Program on Clinical Outcomes in Patients With Musculoskeletal Disorders","Inclusion Criteria:\n\n* Aged 18 years and above\n* Presenting with musculoskeletal disorders leading to pain in the neck, shoulder, low back, or knee\n* Scoring 3 or higher on the Numeric Pain Rating Scale\n\nExclusion Criteria:\n\n* Diagnosis of malignant tumors\n* Presence of serious systemic or neurological conditions that may interfere with assessment or treatment, such as uncontrolled hypertension, serious cardiac diseases, or Parkinson's disease\n* Inability to use a mobile smartphone\n* Pregnancy",{"count":358,"type":21},[24],"Overview This study evaluates the effectiveness of a dedicated mobile health (mHealth) application in supporting home exercise programs for patients with musculoskeletal disorders, such as neck, shoulder, back, or knee pain. The research aims to address the widespread challenge of low patient adherence to unsupervised home-based exercises.\n\nStudy Design The project employs a dual-methodology approach:\n\nClinical Trial: 30 participants presenting with neck, shoulder, back, or knee pain will be randomly assigned to either an app-assisted group or a traditional home exercise group. Both groups will undergo 4 weeks of physiotherapy. The study will compare pain intensity, physical function, and exercise adherence between the two cohorts.\n\nRetrospective Analysis: To complement the trial, the study will analyze a large-scale database containing approximately 700,000 anonymized real-world data entries. This analysis aims to observe real-time pain fluctuations before and after exercise sessions within routine clinical settings.\n\nGoal The primary objective is to determine if integrating mHealth technology into traditional rehabilitation can enhance clinical outcomes and improve patient adherence to home-based exercise routines.",[486,462,487,222,488],"Musculoskeletal Disorders","Neck Pain","Knee Pain",[490,491,492],"e-Health","Mobile Applications","Home Exercise Program","2026-01-12",{"date":495,"type":41},"2026-01-21",{"date":468,"type":21},{"date":498,"type":21},"2026-09-15",{"name":47,"class":48},{"id":501,"slug":502,"hasResults":12,"nctId":503,"briefTitle":504,"officialTitle":505,"acronym":4,"eligibilityCriteria":506,"healthyVolunteers":12,"sex":17,"minAge":507,"maxAge":508,"enrollmentInfo":509,"targetDuration":4,"studyType":22,"phases":511,"briefSummary":512,"conditions":513,"keywords":515,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":521,"lastUpdatePostDateStruct":522,"startDateStruct":524,"completionDateStruct":526,"leadSponsor":528,"locationsCount":49},"100581764","impact-of-picture-book-reading-on-preterm-infant-stability-parental-anxiety-and-parent-child-attachment-100581764","NCT06854549","Impact of Picture Book Reading on Preterm Infant Stability, Parental Anxiety, and Parent-Child Attachment","The Effectiveness of Parental Reading Picture-book Intervention on Cardiopulmonary Stability, Hospitalization Anxiety and Parent-Child Attachment Relationship With Premature Infants","Inclusion Criteria:\n\n* Preterm Infants:\n\n  1. Born between 28+0 and 36+6 weeks of gestation.\n  2. Transferred out of the incubator as per medical advice.\n  3. Passed the newborn hearing screening in both ears.\n* Parents of Preterm Infants:\n\n  1. Able to read and comprehend Chinese-language materials.\n  2. Capable of communicating in Mandarin.\n\nExclusion Criteria:\n\n* Preterm Infants:\n\n  1. Presence of external ear abnormalities.\n  2. Receiving sedatives, hypnotics, or caffeine therapy.\n* Parents of Preterm Infants:\n\n  1. Having auditory or speech impairments.","28 Weeks","37 Weeks",{"count":510,"type":21},88,[24],"This study investigates the effects of a parent-child picture book reading intervention on the cardiopulmonary stability of preterm infants, parental anxiety, and parent-child attachment. A randomized controlled trial will be conducted in a neonatal intensive care unit (NICU) and neonatal intermediate care unit in northern Taiwan. A total of 88 preterm infants and their parents will be randomly assigned to an intervention or control group. Parents in the intervention group will read picture books to their infants from a corrected gestational age of 28 weeks to 36 weeks and 6 days. Physiological data (heart rate, respiratory rate, oxygen saturation, and heart rate variability) and parental anxiety levels will be assessed at multiple time points. The study aims to determine whether this intervention improves infant stability, reduces parental anxiety, and enhances parent-child attachment, contributing to improved neonatal care practices.",[514],"Effects of Parent-Child Reading on Preterm Infant Stability, Parental Anxiety, and Parent-Child Attachment",[516,517,518,519,520],"Reading Picture-book","Premature Infants","Hospitalization anxiety","Cardiopulmonary stability","parent-child attachment relationship","2025-09-24",{"date":523,"type":41},"2025-09-30",{"date":525,"type":41},"2025-06-23",{"date":527,"type":21},"2026-06-28",{"name":47,"class":48},{"id":530,"slug":531,"hasResults":12,"nctId":532,"briefTitle":533,"officialTitle":534,"acronym":535,"eligibilityCriteria":536,"healthyVolunteers":12,"sex":17,"minAge":537,"maxAge":106,"enrollmentInfo":538,"targetDuration":4,"studyType":22,"phases":539,"briefSummary":540,"conditions":541,"keywords":543,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":549,"lastUpdatePostDateStruct":550,"startDateStruct":552,"completionDateStruct":554,"leadSponsor":555,"locationsCount":49},"100581765","therapeutic-robots-for-alleviating-icu-stress-in-children-100581765","NCT06854562","Therapeutic Robots for Alleviating ICU Stress in Children","The Effectiveness of Using a Therapeutic Robot to Alleviate Hospitalization Stress Among Children in Intensive Care Units: A Randomized Controlled Trial","NYMCTU","Inclusion Criteria:\n\n1. Patients admitted to the intensive care unit (ICU).\n2. Age range for enrollment is 8 to 18 years.\n3. Able to stay awake and respond.\n4. Able to communicate in Mandarin or Taiwanese.\n5. Have been informed and have agreed to participate in the study.\n\nExclusion Criteria:\n\n1. Patients with a pacemaker.\n2. Patients who require isolation according to hospital infection control regulations.\n3. Patients with wounds that continue to ooze under the gauze covering.\n4. Patients experiencing vomiting symptoms within the past 24 hours.\n5. Patients assessed by a physician to be in a life-threatening condition.","8 Years",{"count":456,"type":21},[24],"The purpose of this study is: (a) to examine the changes in anxiety, depression symptoms, and positive\u002Fnegative emotions before and after the intervention, as well as before discharge from the intensive care unit (ICU) in the experimental group (using the therapeutic robot PARO), the control group (using a stuffed seal), and the comparison group (receiving standard care). (b) To compare the effectiveness in relieving anxiety, depression symptoms, and positive\u002Fnegative emotions among the experimental group, control group, and comparison group for ICU pediatric and adolescent patients in the school-age period.\n\nThe research questions addressed in this study are:\n\n1. What are the changes in anxiety, depression symptoms, and negative emotions before and after the intervention in the experimental group?\n2. What are the changes in anxiety, depression symptoms, and negative emotions before and after the intervention in the control group?\n3. What are the changes in anxiety, depression symptoms, and negative emotions before and after the intervention in the comparison group?\n4. What is the effectiveness in reducing anxiety after the intervention among the experimental group, control group, and comparison group?\n5. What is the effectiveness in alleviating depression symptoms after the intervention among the experimental group, control group, and comparison group?\n6. What is the effectiveness in reducing negative emotions and increasing positive emotions after the intervention among the experimental group, control group, and comparison group?",[542],"Pediatric Intensive Care Units",[544,545,546,547,548],"Therapeutic Robot","Pediatric Intensive Care Unit (PICU)","School-age Children","Adolescents","Hospitalization Stress Response","2025-09-16",{"date":551,"type":41},"2025-09-22",{"date":553,"type":41},"2025-08-14",{"date":185,"type":21},{"name":47,"class":48},{"id":557,"slug":558,"hasResults":12,"nctId":559,"briefTitle":560,"officialTitle":560,"acronym":4,"eligibilityCriteria":561,"healthyVolunteers":56,"sex":17,"minAge":454,"maxAge":329,"enrollmentInfo":562,"targetDuration":4,"studyType":22,"phases":563,"briefSummary":564,"conditions":565,"keywords":567,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":573,"lastUpdatePostDateStruct":574,"startDateStruct":576,"completionDateStruct":578,"leadSponsor":580,"locationsCount":49},"100585387","effects-of-home-based-lower-extremity-muscle-power-training-on-functional-muscle-and-balance-performance-in-older-adults-100585387","NCT06901700","Effects of Home-based Lower Extremity Muscle Power Training on Functional Muscle and Balance Performance in Older Adults","Inclusion Criteria:\n\n* 65\\~80 years old community-dwelling adults\n* MMSE≥24\n* Use smart phone routinely\n\nExclusion Criteria:\n\n* Recent (\\\u003C1 year) musculoskeletal injury or disability in the lower limbs\n* Unstable cardiovascular, neurological disease, or metabolic disease interfering with participating in the study",{"count":307,"type":21},[24],"Background: Muscle power, defined as the rate at which muscular force is generated to produce movement, declines more rapidly with age than muscle strength. The decline in lower extremity muscle power is associated with reduced functional independence, impaired mobility, and an increased risk of falls among older adults. While power training has been shown to improve muscle power, balance, and functional abilities, the feasibility and effectiveness of home-based interventions have not been thoroughly investigated.\n\nPurpose: The aim of this study is to investigate the effects of home-based lower extremity muscle power training program on functional muscle and balance performance in older adults.\n\nMethods: This is a single-blind, randomized controlled trial. Forty community-dwelling older adults will be recruited and randomly assigned to the experimental group (n=20) and control group (n=20). Participants in the experimental group will complete 24 sessions of home-based lower extremity muscle power training targeting the lower limb muscle groups in 8 weeks. The training intensity will be progressively adjusted according to participants' performance. Participants in the control group will maintain their daily activities. In addition, both groups will receive health education. Primary outcomes include functional muscle power measured by the Four-Step Stair Climb Power Test, functional muscle strength measured by Five Times Sit-to-Stand Test, and the functional balance performance measured by the Mini-BESTest, and Timed Up and Go Test. The fall confidence, as the secondary outcome, will be measured by Falls Efficacy Scale International.\n\nStatistical analysis: The SPSS® version 29 will be used for statistical analysis. Independent-t-test or chi-square test will be conducted to compare the baseline demographic characteristics between groups. Two-way repeated measure ANOVA will be used to compare the differences between groups and times, post-hoc analyses will be performed using Tukey's test. The significance level is set at 0.05.",[566],"Older Adults",[568,569,570,571,572],"Power training","Home-based training","Muscle performance","Balance","Older adults","2025-08-28",{"date":575,"type":41},"2025-09-05",{"date":577,"type":41},"2025-07-16",{"date":579,"type":21},"2026-04-30",{"name":47,"class":48},{"id":582,"slug":583,"hasResults":12,"nctId":584,"briefTitle":585,"officialTitle":586,"acronym":4,"eligibilityCriteria":587,"healthyVolunteers":56,"sex":17,"minAge":156,"maxAge":588,"enrollmentInfo":589,"targetDuration":4,"studyType":22,"phases":591,"briefSummary":592,"conditions":593,"keywords":595,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":599,"lastUpdatePostDateStruct":600,"startDateStruct":602,"completionDateStruct":604,"leadSponsor":605,"locationsCount":49},"100500762","the-effects-of-fnirs-based-neurofeedback-training-on-balance-and-gait-in-parkinsons-disease-100500762","NCT05800470","The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease","The Novel Application of fNIRS-based Neurofeedback to Enhance Effects of Motor Imagery on Balance and Gait Performance in Individuals With Parkinson's Disease","Part 1\n\nAdditional Inclusion Criteria for PD:\n\n1. diagnosis of idiopathic PD by neurologist with Hoehn and Yahr stage \\\u003C 4;\n2. stable medical condition;\n3. capability of walking independently without walking devices.\n\nExclusion Criteria:\n\n1. cognitive impairment indicated by MMSE score \\\u003C 24;\n2. motor imagery ability indicated by KVIQ score \\\u003C 25;\n3. unable recognize 26 letters in the English alphabet\n4. history of diseases or conditions known to interfere with participating this study (e.g. epilepsy, metal implants in the brain, or deep brain stimulation);\n5. diagnosis of any other neurological disease or psychiatric disorder (e.g. stroke, anxiety disorder, or depression);\n6. using central nervous system medications other than for PD, e.g. antiepileptic drugs in recent 3 months.\n\nPart 2\n\nInclusion Criteria:\n\n1. aged 40-85 y\u002Fo;\n2. diagnosis of idiopathic PD by neurologist with Hoehn and Yahr stage \\\u003C 4;\n3. stable medical condition;\n4. capability of walking independently for 10 minutes, which is the time needed for imagery walking training in order to eliminate the possible influence of physical fatigue.\n\nExclusion Criteria:\n\n1. cognitive impairment indicated by MMSE score \\\u003C 24;\n2. history of diseases or conditions known to interfere with participating this study (e.g. epilepsy, metal implants in the brain, or deep brain stimulation);\n3. diagnosis of any other neurological disease or psychiatric disorder (e.g. stroke, anxiety disorder, or depression);\n4. using central nervous system medications other than for PD, e.g. antiepileptic drugs in recent 3 months.","85 Years",{"count":590,"type":21},93,[24],"A cross-sectional study (part 1) aims to investigate the influence of fatigue on the MI ability in PD compared to healthy controls. A randomized controlled trial (part 2) aims to compare the effect of fNIRS-based NFB-MI on balance and gait performance versus MI only in people with PD.",[400,594],"Movement Disorder, Functional",[596,597,598],"Neurofeedback","Motor imagery","Parkinson's disease","2025-08-03",{"date":601,"type":41},"2025-08-07",{"date":603,"type":41},"2025-03-19",{"date":293,"type":21},{"name":47,"class":48},""]