[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"North Carolina Agriculture & Technical State University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":136},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,44,71,104],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100652093","pharmacokinetic-pk-study-of-phytochemicals-in-whole-grains-wgs--corn-100652093",false,"NCT07767162","Pharmacokinetic (PK) Study of Phytochemicals in Whole Grains (WGs)- Corn","Inclusion Criteria:\n\n* Adults aged 25-70 years\n* Body mass index (BMI) between 18 and 30 kg\u002Fm²\n* Able to read, speak, and understand English\n* No known allergy or intolerance to the test foods\n* Normal blood and urine biochemical parameters\n* No antibiotic use within the past 6 months\n* Willing and able to comply with all study procedures, including dietary restrictions throughout the study period\n* No medical conditions or lifestyle factors that, in the opinion of the investigators, would interfere with the study objectives\n\nExclusion Criteria:\n\n* Active disease, including gout, heart disease, peripheral vascular disease, kidney disease, liver disease, cancer, diabetes, gastrointestinal disorders, or endocrine disorders that may interfere with the study\n* Current smoker or use of tobacco products\n* Unwilling or unable to comply with the required dietary restrictions during the study period",true,"ALL","25 Years","70 Years",{"count":20,"type":21},16,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this research study is to identify biomarkers of whole grain (WG) corn intake following an acute exposure in a pharmacokinetic (how the body absorbs, processes, and gets rid of a substance or ingredient) feeding study. In this aim, we will conduct a randomized crossover acute pharmacokinetic study of corn. We will then use a targeted metabolomics approach to identify the exposure markers of corn intake, further develop analytical methods to study its pharmacokinetics, and build our in-house WG metabolite database, and an untargeted metabolomics approach to investigate postprandial biomarkers of corn intake. At the completion of this study, our expectation is that we will identify corn phytochemicals and its metabolites as objective biomarkers of total and individual WG corn that are commonly consumed by Americans.",[27,28],"Healthy Adult Females","Healthy Adult Males",[30],"whole grain corn","RECRUITING","2026-08-11",{"date":34,"type":35},"2026-08-17","ACTUAL",{"date":37,"type":35},"2026-08-04",{"date":39,"type":21},"2026-12-31",{"name":41,"class":42},"North Carolina Agriculture & Technical State University","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":59,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":65,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":43},"100652028","effects-of-flavonoid-foods-on-carbonyl-stress-100652028","NCT07767149","Effects of Flavonoid Foods on Carbonyl Stress","Effects of Flavonoid-rich Foods on Carbonyl Stress","Inclusion Criteria:\n\n* 1\\. Age 25-70 years 2. BMI between 18 and 30 3. Have no known allergy to test food 4. have no known allergies to green tea, apples, blueberries, soy milk, and pineapples 5. Be not engaging in high-intensity exercise 6. Having blood and urine clinical tests in the normal range. 7. Be not taking antibiotics for six months 8. Be not currently taking medication\n\n  1. No taking any prescription drugs\n  2. If supplements were taken, flavonoid-enriched supplements (see list below) should be avoided.\n\n     Major brands Notes Soy Isoflavones All flavonoid-enriched supplements should be avoided. Lipo-Flavonoid Citrus Bioflavonoids Complex Super Flavonoids Super Antioxidants Quercetin Supplement Essential-C and flavonoids Milk Thistle Other flavonoids supplements, including but not limited: Luteolin, Rutin, etc\n  3. No any drugs or supplements within three weeks of the experiment 9. Be nonsmoking 10. Have no alcoholic intoxication\n\n  \u003C!-- -->\n\n  1. No alcoholic addiction\n  2. \\\u003C 3-4 drinks per week (less than 2 glasses (300 mL) per drink)\n  3. No alcohol within 3 three weeks of the experiment 11. Have no extended exposure to industrial wastes\n\nExclusion Criteria:\n\n* 1\\. Disease: gout, heart disease, peripheral vascular disease, degenerative kidney, degenerative liver, diabetes, GI disorders, or endocrine disorders 2. Cancer patients\n\n  1. Currently diagnosed cancer patients will be excluded.\n  2. Medication free for \\>2 years could be considered.",{"count":52,"type":21},36,[24],"This randomized crossover study will compare low- and high-flavonoid diets in healthy adults to identify flavonoid-derived biomarkers in urine and plasma. Using targeted LC-MS metabolomics, researchers will measure known and novel flavonoid metabolites and evaluate whether a higher flavonoid intake reduces carbonyl stress markers, including reactive carbonyl species (RCS) and advanced glycation end products (AGEs).",[56,57,58],"Human Health","Flavonoids","Carbonyl Stress",[60,61,62,63,64],"flavonoids","Carbonyl stress","Advanced glycation end products (AGEs)","Metabolomics","Reactive carbonyl species (RCS)",{"date":34,"type":35},{"date":67,"type":21},"2026-09-02",{"date":69,"type":21},"2027-12-31",{"name":41,"class":42},{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":15,"sex":16,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":84,"conditions":85,"keywords":89,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":43},"100638605","low-energy-availability-and-hypertension-in-division-i-hbcu-athletes-100638605","NCT07583940","Low Energy Availability and Hypertension in Division I HBCU Athletes","Cardiovascular Outcomes and Relative Energy Deficiency in Division I HBCU Athletes: CORE-DI Study","CORE-DI","Inclusion Criteria:\n\nAge: 18-25yrs Sex: Male and Female Training Status\u002FExperience: HBCU Division I collegiate athletes with \\>3yrs of previous competitive experience\n\nExclusion Criteria:\n\n* Persons who self-report any known disease, or unknown issue precluding collegiate competitive participation: Excluded\n* Those who have any orthopedic injuries, concussions, or conditions which would preclude safe testing: Excluded\n* Individuals who are not yet adults \\\u003C18yrs (e.g.: infants, children, teenagers):\n\nExcluded\n\n* Persons who have a pacemaker: Excluded\n* Persons who are pregnant: Excluded","18 Years","26 Years",{"count":82,"type":21},150,"OBSERVATIONAL","Low energy availability (LEA) occurs when the body does not get enough calories to support both daily life and exercise. This can happen when athletes train hard but do not eat enough to match their energy needs. In both 2012 and 2023, the International Olympic Committee on Sports Nutrition recognized LEA as an important factor that can increase the risk of cardiometabolic disease (CMD), which includes conditions like high blood pressure, diabetes, and heart disease. LEA can affect many systems in the body. It may disrupt hormones (such as menstrual cycles), cause changes in blood sugar and cholesterol levels, weaken bones, impair digestion, and negatively impact mental health. Over time, these changes may be linked to chronic inflammation, which plays a key role in the development of disease. Maintaining proper energy balance can be especially challenging for athletes because they often train at levels well above general health recommendations. As a result, even highly fit athletes may unintentionally remain in a calorie deficit. Our recent pilot research found a significant relationship between LEA and high blood pressure in Black Division I collegiate athletes. This is important because this group has historically been understudied and may face a higher risk of serious heart-related events, including sudden cardiac death. Despite assumptions that collegiate athletes are uniformly healthy, there is a need to better understand hidden health risks in this population. Our research aims to improve how we identify and monitor early signs of cardiometabolic disease by examining markers such as inflammation, blood sugar, and cholesterol levels. These insights will help healthcare providers, athletes, and families make more informed decisions about nutrition, training, and long-term health. Ultimately, this work seeks to develop practical, evidence-based strategies to protect athlete health and reduce the risk of serious cardiovascular outcomes.",[86,87,88],"Vascular Stiffness","Hypertension (HTN)","Nutritional Deficiency Related Cardiovascular Risk in Athletes",[90,91,92,93,94,95],"vascular stiffness,","hypertension","nutritional deficiency","energy balance","RED-S","SDOH","2026-05-06",{"date":98,"type":35},"2026-05-13",{"date":100,"type":35},"2026-01-06",{"date":102,"type":21},"2028-06-30",{"name":41,"class":42},{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":15,"sex":16,"minAge":110,"maxAge":111,"enrollmentInfo":112,"targetDuration":4,"studyType":22,"phases":114,"briefSummary":115,"conditions":116,"keywords":119,"overallStatus":127,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":43},"100583625","evaluating-a-digital-intervention-to-improve-adolescent-condom-use-and-communication-100583625","NCT06878755","Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication","Inclusion Criteria:\n\n* 14-17 years old\n* lives in the U.S.\n* identifies as a queer teen guy or sexual minority male\n\nExclusion Criteria:\n\n* younger than 14\n* older than 17\n* does not live in U.S.\n* does not identify as a queer teen guy or sexual minority male","14 Years","17 Years",{"count":113,"type":21},300,[24],"The purpose of this study is to test the effectiveness, likability, and implementation potential of PACT, an adapted digital program to teach non-heterosexual adolescent boys about sexual consent and condom negotiation in a randomized controlled trial over 9 months.",[117,118],"Condomless Sex","Sexual Assault",[120,121,122,123,124,125,126],"online intervention","digital health","sexual consent","condom use","condom negotiation","LGBTQ health","adolescents","NOT_YET_RECRUITING","2026-03-24",{"date":130,"type":35},"2026-03-30",{"date":132,"type":21},"2026-06",{"date":134,"type":21},"2028-01",{"name":41,"class":42},""]