[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Oman Ministry of Health\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":249},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,48,77,99,131,162,188,218],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100652415","single-fraction-and-multifraction-arc-based-radiotherapy-for-painful-bone-metastases-100652415",false,"NCT07772206","Single Fraction and Multifraction Arc-Based Radiotherapy for Painful Bone Metastases","The SMART Trial: A Randomised Feasibility Study Comparing Single Fraction and Multifraction Arc-Based Radiotherapy for Painful Bone Metastases","SMART","Inclusion Criteria:\n\n* Age ≥18 years\n* Histologically proven malignancy\n* Radiological evidence of bone or spine metastases\n* Pain score ≥4 on Numeric Rating Scale (NRS-11)\n* ECOG Performance Status 0-3\n* Life expectancy ≥3 months.\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Spinal cord compression requiring emergency therapy\n* Previous radiotherapy to same site\n* Unstable pathological fracture requiring surgery\n* Pregnancy\n* Inability to provide consent\n* Oligometastatic bone metastases requiring Stereotactic Body Radiotherapy (SBRT)","ALL","18 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective randomised pilot feasibility study will compare single-fraction radiotherapy (8 Gy × 1) with multifraction radiotherapy (20 Gy in 5 fractions) for the palliation of painful bone metastases. The study will evaluate pain response at 4 weeks following radiotherapy, together with feasibility, treatment compliance, toxicity, pain flare, retreatment, patient convenience and resource utilisation. The study will generate preliminary data to inform the design of a future definitive randomised trial.",[27,28],"Bone Metastases of a Malignant Tumor","Cancer Pain",[30,31,32,33,34],"Bone Metastases","Feasibility","Single fraction radiotherapy","Multifraction radiotherapy","Pain response,","NOT_YET_RECRUITING","2026-08-14",{"date":38,"type":39},"2026-08-19","ACTUAL",{"date":41,"type":21},"2026-09-01",{"date":43,"type":21},"2027-12-30",{"name":45,"class":46},"Oman Ministry of Health","OTHER_GOV",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100648342","phase-4-telestroke-guided-thrombolysis-for-acute-ischemic-stroke-in-oman-100648342","NCT07721129","TeleStroke-Guided Thrombolysis for Acute Ischemic Stroke in Oman","Thrombolysis for Acute Ischemic Stroke Facilitated by TeleStroke: Oman TeleStroke Initiative","Inclusion Criteria:\n\n* Age \\>18 years. Acute neurologic deficits due to cerebral ischemia\u002Finfarction. Clearly defined onset with duration from stroke onset of \\\u003C4.5 hours. Significant neurological deficit (usually NIHSS score of 4-25).\n\nExclusion Criteria:\n\n* CT brain shows showing evidence of intracranial hemorrhage\n* CT brain showing acute or subacute infarct of size about \\>1\u002F3 Middle Cerebral Artery territory.\n* Arterial puncture at non compressible site in previous 7 days\n* History of previous intracranial hemorrhage.\n* Intracranial neoplasm, AV malformation, or aneurysm\n* Recent head injury OR intracranial or intraspinal surgery in last 3 mo.\n* Persistent Elevated BP \\>185\u002F110 mm Hg despite treatment.\n* Active ongoing internal bleeding.\n* Platelet count \\\u003C100 000\u002Fmm3.\n* Current use of NOACs OR warfarin with INR \\>1.7 OR Inj.Enoxaparin\u002FHeparin in therapeutic dose\n* Blood glucose concentration \\\u003C2.7mmol\u002FL (\\\u003C50mg\u002Fdl).\n\nRelative contraindications: (may consider IV alteplase on individual evaluation).\n\n* Seizure at onset with post ictal residual neurological deficit.\n* Signs of mild stroke in isolation or rapidly improving symptoms.\n* Pregnancy.\n* Recent GI or UT hemorrhage within the last 21 days.\n* Recent MI within previous 3 months (to exclude anterolateral infarct \u002F STEMI)",{"count":56,"type":21},200,[58],"PHASE4","The goal of this study is to establish and examine the efficacy of using a Telestroke network in Oman to facilitate using emergent thrombolysis for patients with acute ischemic stroke encountered in selected peripheral hospitals. It is proposed to establish a TeleStroke network involving two central hospitals in Muscat linked to three to five peripheral hospitals in Oman which currently have access to CT scans and basic infrastructure for management of AIS patients- but do not have a Neurology service. Selected staff from Internal Medicine\u002FEmergency Medicine departments, Nursing, Technical service and support staffs will be trained in the process of assessment and management of AIS patients including the use of IV alteplase or tenecteplase. They will also be trained in timely access of a Neurologist on call at the central hospital(s) using a TeleStroke network. The Neurologist would conduct a Telestroke based clinical assessment of the AIS patient, review imaging and laboratory results in a timely manner and advice the medical team at the peripheral hospital regarding administration of IV alteplase\u002Ftenecteplase. The main purpose of such consultation would be to recognize eligible patients for administration of IV thrombolysis safely at the earliest opportunity within 4.5 hours, leading to increased rates of such thrombolysis with expected improved outcomes. Outcomes would be compared among 100 patients with AIS managed across these 5 hospitals prior to initiation of the practice of thrombolysis and at least 100 patients treated each with IV alteplase using TeleStroke Consultation with Neurologist. Demonstration of efficacy of TeleStroke based stroke thrombolysis would lead to effective implementation of this practice in Oman.",[61,62],"Ischemic Stroke, Acute","Ischemic Stroke",[64,65,66,67,68],"Stroke","Acute Ischemic Stroke","Thrombolysis","Telestroke","Telemedicine","2026-07-19",{"date":71,"type":39},"2026-07-22",{"date":73,"type":21},"2026-08-01",{"date":75,"type":21},"2027-03-30",{"name":45,"class":46},{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":4},"100644855","ice-cold-water-flushing-of-the-ampulla-after-endoscopic-sphincterotomy-to-reduce-post-ercp-pancreatitis-100644855","NCT07677397","Ice Cold Water Flushing of the Ampulla After Endoscopic Sphincterotomy to Reduce Post-ERCP Pancreatitis","A Multicenter Randomized Controlled Trial of Ice Cold Water Flushing of the Ampulla After Endoscopic Sphincterotomy to Reduce Post-ERCP Pancreatitis","ERCP","Inclusion Criteria:\n\n* All adults (agesld 18 years old) scheduled for an endoscopic sphincterotomy at the participating hospitals.\n\nExclusion Criteria:\n\n* Patients with missing data, acute or chronic pancreatitis, pancreatic cancer, or those unable to provide informed consent.",{"count":86,"type":21},210,[24],"Endoscopic retrograde cholangiopancreatography (ERCP) is an essential diagnostic and therapeutic tool used to manage diseases of the pancreatic and biliary systems. During the procedure, an upper endoscope is used to reach the major duodenal papilla, and a contrast material is injected into the ducts for radiologic imaging. In an endoscopic sphincterotomy, a specialized knife cuts the biliary sphincter to treat papilla conditions or facilitate therapeutic interventions.\n\nThe most common complication following an ERCP is pancreatitis, carrying an incidence rate of 3.5% to 9.7%. Standard preventive strategies currently include careful patient selection, rectal administration of NSAIDs (like indomethacin or diclofenac), aggressive intravenous hydration, and pancreatic stent placement.\n\nThe Innovation: Flushing the ampulla with ice-cold water after a sphincterotomy is a safe,easy, and cost-effective evolving intervention. While initial data demonstrates its safety,there is a clear deficiency in multicenter randomized trials assessing its overall clinical effectiveness, and no such studies have been conducted in the Gulf region. The primary goal of this study is to evaluate the effectiveness of ice-cold water flushing ofthe ampulla after endoscopic sphincterotomy in reducing the incidence of post-ERCP pancreatitis.",[90],"Post ERCP Pancreatitis","2026-06-27",{"date":93,"type":39},"2026-06-30",{"date":95,"type":21},"2026-06-28",{"date":97,"type":21},"2027-06-30",{"name":45,"class":46},{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":105,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":22,"phases":109,"briefSummary":110,"conditions":111,"keywords":114,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":4},"100641748","the-effect-of-motivational-interviewing-on-treatment-adherence-and-self-efficacy-among-omani-adults-with-thalassemia-100641748","NCT07660224","The Effect of Motivational Interviewing on Treatment Adherence and Self-Efficacy Among Omani Adults With Thalassemia","The Effect of Motivational Interviewing on Treatment Adherence and Self-Efficacy Among Omani Adults With Beta-Thalassemia Major","MITAS","Inclusion Criteria:\n\n* Adults aged 18 years and older.\n* Diagnosed with transfusion-dependent beta-thalassemia major.\n* Receiving iron chelation therapy for at least 6 months.\n* Receiving regular follow-up at the participating study sites.\n* Able to communicate in Arabic or English.\n* Willing and able to provide informed consent.\n* Able to attend the motivational interviewing sessions and complete study questionnaires.\n\nExclusion Criteria:\n\n* Current hospitalization for an acute medical condition at the time of recruitment.\n* Severe cognitive impairment or psychiatric illness that may affect participation.\n* Participation in another structured psychosocial or behavioral intervention program.\n* Unable or unwilling to provide informed consent.",{"count":108,"type":21},45,[24],"Beta-thalassemia major is a chronic hereditary blood disorder that requires lifelong treatment, including regular blood transfusions and iron chelation therapy. Poor adherence to treatment remains a significant challenge and may lead to iron overload and related complications. Self-efficacy is an important factor influencing patients' ability to adhere to treatment recommendations.\n\nThis study aims to evaluate the effect of nurse-delivered Motivational Interviewing (MI) on treatment adherence and self-efficacy among Omani adults with beta-thalassemia major. A pre-experimental one-group repeated-measures design will be used. Approximately 45 participants will be recruited from the Oman National Center for Hematology and Bone Marrow Transplantation and Royal Hospital in Muscat, Oman.\n\nParticipants will receive three individualized MI sessions over a period of six to eight weeks. Treatment adherence and self-efficacy will be assessed at baseline, immediately after completion of the intervention, and at three-month follow-up. Secondary outcomes include serum ferritin level and frequency of thalassemia-related hospital admissions. The findings will provide evidence regarding the usefulness of motivational interviewing in improving adherence-related outcomes among adults with beta-thalassemia major.",[112,113],"Beta-Thalassemia Major","Transfusion-Dependent Thalassemia",[115,112,116,117,118,119,120,121,122],"Motivational Interviewing","Treatment Adherence","Self-Efficacy","Iron Chelation Therapy","Adult Patients","Nursing Intervention","Thalassemia","Oman","2026-06-16",{"date":125,"type":39},"2026-06-22",{"date":127,"type":21},"2026-11-01",{"date":129,"type":21},"2027-11-30",{"name":45,"class":46},{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":17,"minAge":138,"maxAge":139,"enrollmentInfo":140,"targetDuration":4,"studyType":22,"phases":142,"briefSummary":144,"conditions":145,"keywords":147,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":159,"leadSponsor":161,"locationsCount":47},"100624701","phase-3-comparative-efficacy-of-4-mg-vs-8-mg-submucosal-dexamethasone-in-postoperative-pain-management-after-dental-implant-surgery-a-randomized-double-blind-controlled-clinical-trial-100624701","NCT07413055","Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial","Comparative Efficacy of 4 mg vs. 8 mg Submucosal Dexamethasone in Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial","Inclusion Criteria:\n\n* Males \\& females\n* Age range (21-80)\n* ASA I \\& II according to (American Society of Anesthesiologists) classification\n* Single tooth implant\n* Type 3 \\& type 4 implant placement timing (Chen and Buser, 2009)\n\nExclusion Criteria:\n\n* Any known allergy to any medications which will be used in the study\n* Smokers\u002F Alcoholics\n* Pregnant and lactating women\n* Bone augmentation\u002F sinus lifting required during the surgery\n* The need of antibiotic prophylaxis","21 Years","80 Years",{"count":141,"type":21},138,[143],"PHASE3","This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site.\n\nLater, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded.\n\nPreoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores.\n\nThe results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.",[146],"Postoperative Pain",[148,149,150,151,152,153],"Dexamethasone","Dental implants","Postoperative pain","Submucosal injection","Analgesic consumption","Anxiety","RECRUITING","2026-03-25",{"date":157,"type":39},"2026-03-30",{"date":155,"type":21},{"date":160,"type":21},"2026-12-01",{"name":45,"class":46},{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":11,"sex":17,"minAge":169,"maxAge":4,"enrollmentInfo":170,"targetDuration":4,"studyType":22,"phases":172,"briefSummary":173,"conditions":174,"keywords":176,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":183,"completionDateStruct":185,"leadSponsor":187,"locationsCount":47},"100630697","impact-of-sglt2-inhibitors-on-chronic-peritoneal-dialysis-patients-100630697","NCT07491042","Impact of SGLT2 Inhibitors on Chronic Peritoneal Dialysis Patients.","Impact of SGLT2 Inhibitors on Chronic Peritoneal Dialysis Patients: A Six-month Prospective .Study","Inclusion Criteria:\n\n* o age equal to or more than13 years.\n\n  * All genders.\n  * All patients undergoing chronic Peritoneal Dialysis.\n  * Urine output equal or more than 150 ml\u002F24 hours.\n\nExclusion Criteria:\n\n* o Age less than 13 years\n\n  * Patients with type I diabetes mellitus.\n  * Patients with recurrent urinary tract infection (UTI) or peripheral vascular diseases (P.V.D).\n  * Patients with urine output less than 150 ml\u002F24hours.\n  * Patients with recurrent hypoglycemic episodes\n  * Patients with acute or chronic liver disease,\n  * Patients who refuse to participate in the study.\n  * peritoneal Dialysis catheter (PDC) related peritonitis in last 3 months","13 Years",{"count":171,"type":21},38,[24],"This project aims to examine the effects of six-month treatment with selective SGLT2 inhibitor dapagliflozin in patients with end-stage kidney disease on chronic peritoneal dialysis.\n\nMethods: A prospective, open label, single-arm interventional clinical trial, will conduct at Nizwa Hospital from March 1st, 2026, to August 31th , 2026, and includes thirty (30) end-stage kidney disease diabetic and non-diabetic patients on chronic peritoneal dialysis, will receive selective SGLT2i Dapagliflozin 10 mg once daily (OD). Clinical and laboratory parameters will be assessed at baseline, then three and six months after drug initiation.\n\nThe primary outcomes are:1- change in ultrafiltration volume, 2- change in Kt\u002FV (dialysis adequacy), 3. Change in the mean 24-hour urine volume.",[175],"End Stage Chronic Renal Failure",[177,178,179],"SGLT-2 inhibitor","Peritoneal Dialysis","urine volume","2026-03-19",{"date":182,"type":39},"2026-03-24",{"date":184,"type":21},"2026-04-01",{"date":186,"type":21},"2027-01-31",{"name":45,"class":46},{"id":189,"slug":190,"hasResults":11,"nctId":191,"briefTitle":192,"officialTitle":193,"acronym":4,"eligibilityCriteria":194,"healthyVolunteers":11,"sex":17,"minAge":195,"maxAge":169,"enrollmentInfo":196,"targetDuration":4,"studyType":22,"phases":198,"briefSummary":199,"conditions":200,"keywords":202,"overallStatus":154,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":47},"100624406","the-use-of-an-audio-visual-method-in-counseling-for-pediatric-lumbar-puncture-procedure-100624406","NCT07409220","The Use of an Audio-visual Method in Counseling for Pediatric Lumbar Puncture Procedure","The Use of an Audio-visual Method in Counseling for Pediatric Lumbar Puncture Procedure. A Randomized Controlled Trial.","Inclusion Criteria:\n\n* All Parents\u002Flegal guardians of 0-13 years old children who were identified to get an emergent lumbar puncture procedure, as decided by the attending physician during the Emergency Department shift.\n* Participants who speak Arabic or English\n\nExclusion Criteria:\n\n\\- Participants who are not Arabic nor English speakers.","12 Hours",{"count":197,"type":21},154,[24],"The goal of this clinical trial is to compare the use of usual verbal counseling supported by a video illustration comparing to the use of usual verbal counseling alone prior to obtaining spinal fluid ( Lumbar puncture - LP ) procedure, from children suspected to have brain infection in the Emergency department settings.\n\nThis trial is trying to answer if use of video illustration is associated with higher acceptance rate for the procedure by the parents of children who are suspected to have brain infection (meningitis) in the pediatric emergency room settings at a tertiary hospital.\n\nWho is suitable to participate? Parents\u002Flegal guardians of all children aged between 1day to 12 years, who are suspected to have brain infection (meningitis) attending the Pediatric emergency room at the Royal Hospital.\n\nParticipants will:\n\nBe counseled using verbal snd video method = Intervention group OR verbal method only = Control group The Researchers will collect the acceptance rate in performing LP in both groups.",[201],"Meningitis in Children",[203,204,205,206,207,208,209],"lumbar puncture","counseling","audiovisual aids","verbal","video","emergency","pediatrics","2026-02-11",{"date":212,"type":39},"2026-02-13",{"date":214,"type":39},"2025-01-31",{"date":216,"type":21},"2026-07-30",{"name":45,"class":46},{"id":219,"slug":220,"hasResults":11,"nctId":221,"briefTitle":222,"officialTitle":223,"acronym":4,"eligibilityCriteria":224,"healthyVolunteers":225,"sex":17,"minAge":138,"maxAge":4,"enrollmentInfo":226,"targetDuration":4,"studyType":22,"phases":228,"briefSummary":229,"conditions":230,"keywords":235,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":47},"100600686","intervention-study-on-compassion-fatigue-and-satisfaction-in-omani-nurses-100600686","NCT07100717","Intervention Study on Compassion Fatigue and Satisfaction in Omani Nurses","Compassion Fatigue and Compassion Satisfaction Among Nurses in Oman: Intervention Study","Inclusion Criteria:\n\n* Registered nurses (males \\& females; Omani \\& Non-Omani)\n* With direct patient care\n* A minimum of six months experience in same hospital's unit\u002Fword\n* Currently not receiving psychiatric or mental therapy\n\nExclusion Criteria:\n\n* Registered nurses with no direct patient care\n* Less than six months of work experience in a hospital unit\u002Fword\n* Currently under psychiatric or mental therapy",true,{"count":227,"type":21},50,[24],"The purpose of this study is to assess the level of compassion fatigue and compassion satisfaction among nurses working at Ministry of Health hospitals. It will also examine the significant demographics, work-related contributing factors, and the impact of a mindfulness self-care program on nurses' compassion fatigue and compassion satisfaction level.",[231,232,233,234],"Registered Nurses","Compassion Fatigue","Occupational Stress","Mental Health",[236,122,232,237,238,239,240,234],"Nurses","Compassion Satisfaction","Burnout","Intervention","Healthcare Workers","2025-07-27",{"date":243,"type":39},"2025-08-03",{"date":245,"type":21},"2025-09-21",{"date":247,"type":21},"2027-12-31",{"name":45,"class":46},""]