[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Orivian inc\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":52},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100647850","hme-amino-acid-supplementation-for-strength-performance-and-recovery-in-trained-adult-males-100647850",false,"NCT07715201","HME Amino Acid Supplementation for Strength, Performance, and Recovery in Trained Adult Males","A Pilot Randomized, Double-Blind, Placebo-Controlled Trial of HME (Human Muscle Equivalent) Supplementation on Strength, Body Composition, Athletic Performance, and Recovery in Trained Adults","Inclusion Criteria:\n\n* Age 18 to 45 years inclusive\n* Biological male\n* Active competitive athlete in a recognized sport OR certified fitness professional (personal trainer, strength and conditioning coach, or equivalent)\n* Minimum 3 structured resistance-training sessions per week for at least 1 year continuously\n* Habitual protein intake 1.2 to 2.0 g\u002Fkg\u002Fday confirmed by 7-day food diary at screening\n* Current creatine users willing to use study-provided creatine monohydrate 5 g\u002Fday; non-users willing not to initiate creatine during the trial\n* Able to provide written informed consent in English\n* Willing and able to attend all supervised training sessions and assessment visits for 10 weeks\n* Access to a digital kitchen scale or willing to obtain one for food-record completion\n\nExclusion Criteria:\n\n* Use of anabolic steroids, SARMs, prohormones, or beta-alanine supplements (other than the study product) within 8 weeks of screening\n* Current use of any amino acid supplement or weight-gainer product not cleared by the research coordinator\n* Currently in an active competitive season with non-negotiable training demands the investigator determines are incompatible with the supervised programme\n* Musculoskeletal injury in the preceding 3 months affecting ability to perform study assessments or training\n* Any medical condition, medication, or dietary restriction that in the Medical Officer's opinion would affect the safety or validity of participation\n* Participation in another intervention study within 4 weeks of screening\n* Unwillingness to standardize creatine intake per protocol (current users) or to abstain from initiating creatine (non-users)",true,"MALE","18 Years","45 Years",{"count":21,"type":22},50,"ESTIMATED","INTERVENTIONAL",[25],"NA","This pilot randomized controlled trial evaluates HME (Human Muscle Equivalent), a free-form amino acid supplement formulated to match the amino acid composition of human skeletal muscle, taken at its Health Canada licensed dose (3 g powder plus one 50 mg slow-release beta-alanine capsule daily). Trained adult males (competitive athletes or certified fitness professionals) are randomized to HME or an identical-appearing placebo for 10 weeks: a 2-week supplement-only lead-in followed by 8 weeks of supplement plus supervised resistance training. The primary aim is to estimate the effect of HME on composite maximal strength (1-repetition maximum leg press plus chest press) compared with placebo. Secondary measures include isometric knee-extension strength, countermovement jump height, and subjective recovery.",[28,29,30],"Muscle Strength","Athletic Performance","Resistance Training",[32,33,34,35,36,37,38,39],"amino acids","human muscle equivalent","dietary supplement","HME","body composition","recovery","sports nutrition","1-RM","RECRUITING","2026-07-21",{"date":43,"type":44},"2026-07-23","ACTUAL",{"date":46,"type":44},"2026-06-29",{"date":48,"type":22},"2027-03-30",{"name":50,"class":51},"Orivian inc","INDUSTRY",""]