[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Pamukkale University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":649},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,41,0,25,[9,50,75,101,129,161,190,214,237,266,289,314,336,359,383,406,429,454,482,507,526,554,576,600,623],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100629327","comparison-of-platelet-rich-plasma-and-activated-cytokine-rich-serum-injection-treatments-in-patients-with-knee-osteoarthritis-koa-prp-acs-100629327",false,"NCT07473232","Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS)","KOA PRP ACS","Inclusion Criteria:\n\n1. Diagnosis of knee osteoarthritis according to ACR criteria at least 6 months ago.\n2. Being between grade 1-2 according to the Kellgren-Lawrence radiological classification.\n3. Not having had PRP injection in the last year.\n4. Knee pain ≥ 5 according to the visual pain scale.\n\nExclusion Criteria:\n\n1. Those with significant neurological or cardiovascular disorders.\n2. Those with active thrombovascular disease.\n3. Those with joint or skin infections.\n4. Those who have recently had an infectious disease.\n5. Those infected with Hepatitis B, C, and HIV.\n6. Those who have received intra-articular knee injections (hyaluronic acid, PRP, corticosteroids, and others) within the last year.\n7. Those who use oral corticosteroids.\n8. Those who have used NSAIDs within the last week.\n9. Those who have used anti-platelet or anti-aggregant drugs within the last week.\n10. Those with coagulation disorders.\n11. Those with hemoglobin \\\u003C10 g\u002Fdl and platelet count \\\u003C100,000\n12. Those with cancer.\n13. Pregnant or breastfeeding women, drug addicts.\n14. Those scheduled for knee surgery or arthroscopy, or those who have undergone knee surgery or arthroscopy.\n15. Those with diseases causing secondary osteoarthritis:\n\n    1. post-traumatic,\n    2. congenital or developmental diseases\n\n       1. Local diseases (leg length discrepancy, varus, valgus deformities, hypermobility syndromes, scoliosis)\n       2. Generalized diseases (Bone dysplasias, Metabolic disorders (hemochromatosis, ochronosis, Gaucher disease, hemoglobinopathy, Ehlers-Danlos disease))\n    3. Calcium storage diseases (calcium pyrophosphate storage disease, etc.)\n    4. Other bone and joint diseases (avascular necrosis, rheumatoid arthritis, gouty arthritis, septic arthritis, Paget's disease, osteoporosis, osteochondritis)\n    5. Other diseases\n\n       1. Endocrine diseases (Diabetes mellitus, acromegaly, hypothyroidism, hyperthyroidism)\n       2. Neuropathic arthropathy (Charcot joint)\n       3. Other (Frost, Kashin-Beck disease, Caisson disease) -","ALL","40 Years","80 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","The effects of single dose injection of platelet rich plasma or conditioned serum in the knee joint in patients with knee osteoarthritis will be compared",[28,29,30],"Knee Arthritis Osteoarthritis","Platelet Rich Plasma Injection","Conditioned Serum",[32,33,34,35,36],"knee osteoarthritis","platelet rich plasma injection","conditioned serum injection","inflammation","cartilage","RECRUITING","2026-08-19",{"date":40,"type":41},"2026-08-20","ACTUAL",{"date":43,"type":41},"2026-04-01",{"date":45,"type":22},"2026-10-30",{"name":47,"class":48},"Pamukkale University","OTHER",1,{"id":51,"slug":52,"hasResults":12,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":4},"100652660","manual-therapy-vs-multicomponent-exercise-in-cervicogenic-headache-100652660","NCT07776093","Manual Therapy vs. Multicomponent Exercise in Cervicogenic Headache","Effects of Manual Therapy Versus Multicomponent Exercise on Sensorimotor Function, Suboccipital Muscle Thickness, and Central Sensitization in Cervicogenic Headache: A Double-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of cervicogenic headache by a specialist physician,\n* Aged between 18 and 45 years,\n* Ability to read and write (literate),\n* Provision of signed informed consent to participate in the study.\n\nExclusion Criteria:\n\n* History of head or neck surgery,\n* History of spinal surgery,\n* History of severe cardiac conditions or cardiac surgery that contraindicates exercise,\n* History of ongoing or past malignancy,\n* Diagnosis of psychiatric disorders,\n* Diagnosis of migraine,\n* Diagnosis of fibromyalgia,\n* Having received medical (except analgesics), physical therapy, or other interventions (e.g., alternative medicine, massage therapy) for cervicogenic headache within the last 6 months,\n* Engaging in regular exercise or attending an exercise facility within the last 6 months,\n* Experiencing headaches strictly associated with the menstrual period,\n* Investigator decision for exclusion based on ethical or clinical grounds,\n* Communication problems interfering with evaluation and treatment.","18 Years","45 Years",{"count":60,"type":22},32,[25],"The purpose of this study is to compare the effects of manual therapy and a multicomponent exercise program on suboccipital muscle thickness, joint position sense, pain, central sensitization, balance, and kinesiophobia in patients diagnosed with cervicogenic headache.\n\nCervicogenic headache is a common secondary headache originating from dysfunction in the upper cervical spine. Dysfunction in the deep neck muscles, impaired neck joint awareness, and heightened pain sensitivity (central sensitization) are frequently observed in these patients. While both manual therapy and targeted exercise are used in physiotherapy practice, evidence regarding their direct comparative effects on suboccipital muscle morphology and somatosensory parameters remains limited.\n\nParticipants will be randomly assigned to one of two treatment groups for a duration of 4 weeks (12 sessions total):\n\n1. Manual Therapy Group: Receives joint mobilization, myofascial release, trigger point release, and suboccipital distraction targeting the cervical region.\n2. Multicomponent Exercise Group: Receives deep cervical flexor strengthening, cervical proprioception training, head-eye coordination training, and progressive balance exercises.\n\nThe main questions the study aims to answer are:\n\n* Do manual therapy and multicomponent exercise improve suboccipital muscle thickness and cervical joint position sense in patients with cervicogenic headache?\n* Is there a significant difference between manual therapy and multicomponent exercise in reducing pain intensity, central sensitization, disability, and fear of movement (kinesiophobia)? It is hypothesized that both intervention protocols will yield significant clinical improvements, with specific synergistic adaptations in muscle structure, somatosensory system processing, and pain-related fear.",[64,65,66],"Cervicogenic Headache","Proprioceptive Disorders","Neck Pain Musculoskeletal","NOT_YET_RECRUITING","2026-08-17",{"date":40,"type":41},{"date":71,"type":22},"2026-09-01",{"date":73,"type":22},"2027-03-31",{"name":47,"class":48},{"id":76,"slug":77,"hasResults":12,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":84,"minAge":57,"maxAge":85,"enrollmentInfo":86,"targetDuration":4,"studyType":23,"phases":88,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":49},"100641580","effects-of-passive-recovery-methods-after-high-intensity-cycling-exercise-100641580","NCT07652398","Effects of Passive Recovery Methods After High-Intensity Cycling Exercise","Acute Effects of Five Passive Recovery Interventions Following High-Intensity Cycling Exercise: A Randomized Five-Period Crossover Trial","RECOVER-CYCLE","Inclusion Criteria:\n\n* Healthy adult volunteers aged 18-30 years\n* Able to perform high-intensity cycling exercise\n* No musculoskeletal injury within the last six months\n* No known cardiovascular, neurological, or metabolic disease\n* Not using medication that may affect exercise performance, pain perception, or recovery\n* Willing to attend all five study sessions\n* Willing to receive all five passive recovery interventions\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Presence of acute or chronic musculoskeletal injury\n* History of cardiovascular, neurological, respiratory, or metabolic disease\n* Contraindication to high-intensity exercise\n* Contraindication to compression therapy, vacuum therapy, kinesiology taping, passive rest, or classical massage\n* Skin allergy, open wound, dermatological disease, or sensitivity to kinesiology tape\n* Use of analgesic, anti-inflammatory, muscle relaxant, or performance-enhancing medication during the study period\n* Participation in another exercise or recovery intervention study during the study period\n* Failure to attend all study sessions or comply with study procedures",true,"FEMALE","30 Years",{"count":87,"type":22},12,[25],"This randomized crossover trial will investigate the acute effects of five passive recovery interventions following a standardized high-intensity cycling exercise protocol. Participants will complete the standardized high-intensity cycling exercise protocol during five separate study sessions. Immediately after each exercise session, participants will receive one of five recovery interventions: compression therapy, vacuum therapy, kinesiology taping, passive rest, or classical massage. The order of the interventions will be randomized according to a balanced crossover sequence. Each participant will experience all five recovery interventions during the study period. Outcomes related to post-exercise recovery will be assessed across intervention periods.",[91,92],"Young Adult Health","Young Adults","2026-08-07",{"date":95,"type":41},"2026-08-11",{"date":97,"type":41},"2026-06-22",{"date":99,"type":22},"2026-08-21",{"name":47,"class":48},{"id":102,"slug":103,"hasResults":12,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":12,"sex":108,"minAge":57,"maxAge":19,"enrollmentInfo":109,"targetDuration":4,"studyType":23,"phases":111,"briefSummary":112,"conditions":113,"keywords":116,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":49},"100649952","transcutaneous-tibial-nerve-stimulation-for-urinary-incontinence-after-radical-prostatectomy-100649952","NCT07742176","Transcutaneous Tibial Nerve Stimulation for Urinary Incontinence After Radical Prostatectomy","Efficacy of Transcutaneous Tibial Nerve Stimulation in Patients With Urinary Incontinence After Radical Prostatectomy: A Randomized, Double-Blind, Sham-Controlled Clinical Trial","Inclusion Criteria:\n\n* Male patients aged 18-80 years\n* Urinary incontinence greater than 8 g on the 24-hour pad test after radical prostatectomy\n* Postoperative catheter removed, between 2 weeks and 1 year after surgery\n* Willing to complete study questionnaires and able to understand the procedures, benefits, and possible side effects\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* History of urinary incontinence prior to radical prostatectomy\n* History of conservative treatment after prostatectomy, including tibial nerve stimulation, magnetic stimulation, or electrical stimulation\n* Prolonged indwelling urethral catheterization (more than 15 days)\n* Anatomical\u002Fpost-traumatic malformations or active skin conditions at electrode sites preventing electrode application or stimulation\n* History of prior urological surgery\n* Inability to voluntarily contract pelvic floor muscles on digital rectal examination per ICS terminology\n* Currently receiving or having received radiotherapy\n* Urethral stricture or active urinary tract infection\n* Heart failure, pacemaker, or implanted defibrillator\n* History of transurethral resection of the prostate (TURP) for benign prostatic hyperplasia\n* Use of medications that may affect bladder function (antimuscarinics, duloxetine, tricyclic antidepressants, etc.)\n* History of neurogenic bladder or peripheral\u002Fcentral neurological pathology\n* Inability to attend treatment sessions regularly due to distance or physical limitations","MALE",{"count":110,"type":22},104,[25],"Urinary incontinence (UI) after radical prostatectomy (RP) is a common postoperative complication that significantly affects quality of life. This study aims to evaluate the efficacy of active transcutaneous tibial nerve stimulation (TTNS), added to standard pelvic floor muscle training (PFMT), compared with sham TTNS, in patients with UI after RP. The study uses a randomized, double-blind, sham-controlled design. The primary outcome is incontinence severity measured by the 24-hour pad test. Secondary outcomes include voiding diary parameters, pelvic floor muscle strength (perineometry), quality of life, sexual function, and anxiety\u002Fdepression levels.",[114,115],"Urinary Incontinence (UI)","Prostatectomy",[117,118,119,120],"Radical prostatectomy","Urinary incontinence","Pelvic floor muscle training","Transcutaneous tibial nerve stimulation","2026-08-05",{"date":123,"type":41},"2026-08-06",{"date":125,"type":22},"2026-08",{"date":127,"type":22},"2027-12",{"name":47,"class":48},{"id":130,"slug":131,"hasResults":12,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":135,"eligibilityCriteria":136,"healthyVolunteers":12,"sex":84,"minAge":57,"maxAge":137,"enrollmentInfo":138,"targetDuration":4,"studyType":23,"phases":140,"briefSummary":141,"conditions":142,"keywords":145,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":49},"100650296","dance-based-exercise-versus-clinical-pilates-in-women-with-overweight-or-obesity-100650296","NCT07745166","Dance-Based Exercise Versus Clinical Pilates in Women With Overweight or Obesity","Comparison of Dance-Based Exercise and Clinical Pilates in Terms of Exercise Adherence, Acceptability, and Clinical Outcomes in Women With Overweight or Obesity: A Randomized Active-Comparator Trial","DANCE-PIL","Inclusion Criteria:\n\n* Female gender\n* Aged 18 to 60 years\n* Body Mass Index (BMI) between 25 and 35 kg\u002Fm²\n* Clinically stable\n* Able to participate regularly in the exercise program\n* Volunteering to participate and providing written informed consent\n\nExclusion Criteria:\n\n* Being pregnant or breastfeeding\n* Currently on an active weight loss diet\n* Receiving pharmacological treatment for obesity\n* History of bariatric surgery\n* Uncontrolled hypertension, uncontrolled diabetes, unstable cardiac disease, or serious cardiovascular risk for exercise\n* Chronic respiratory system disease significantly affecting exercise tolerance\n* Cancer, cerebrovascular disease, or severe systemic disease preventing safe exercise\n* Musculoskeletal injury, neurological disease, or significant balance\u002Fvestibular\u002Fvisual problems affecting exercise participation\n* Uncontrolled psychiatric illness\n* Acute infection\n* Participating in a structured exercise program within the last 6 months\n* Transport, time, or health barriers preventing regular attendance","60 Years",{"count":139,"type":22},50,[25],"Purpose of the Study:\n\nRegular physical activity is key in managing overweight and obesity, but keeping up with a program can be challenging. The main purpose of this study is to compare how well women with overweight or obesity stick to (adhere to) a 10-week dance-based exercise program versus a clinical Pilates program. The study also aims to explore how enjoyable, acceptable, and tolerable both programs are, and how they affect participants' quality of life, physical activity levels, body measurements, and physical performance.\n\nWhat the Study Involves:\n\nFemale volunteers aged 18 to 60 with a body mass index (BMI) between 25 and 35 kg\u002Fm² will be randomly assigned to one of two groups:\n\n1. Dance-Based Exercise Group: Participants will join group dance sessions designed with low-impact, rhythmic movements to avoid joint strain.\n2. Clinical Pilates Group: Participants will join group Pilates sessions on mats, focusing on core stability, posture, breathing, and muscle control.\n\nBoth programs will run for 10 weeks, with face-to-face sessions held twice a week for about 45 to 60 minutes under the supervision of a physiotherapist. Participants will be evaluated before starting the exercise programs and immediately after completing the 10-week intervention.",[143,144],"Overweight","Obesity",[143,144,146,147,148,149,150,151,152],"Exercise Adherence","Clinical Pilates","Dance-Based Exercise","Acceptability","Women's Health","Physical Performance","Quality of Life","2026-07-30",{"date":155,"type":41},"2026-08-04",{"date":157,"type":22},"2026-09",{"date":159,"type":22},"2027-05",{"name":47,"class":48},{"id":162,"slug":163,"hasResults":12,"nctId":164,"briefTitle":165,"officialTitle":166,"acronym":4,"eligibilityCriteria":167,"healthyVolunteers":12,"sex":84,"minAge":57,"maxAge":137,"enrollmentInfo":168,"targetDuration":4,"studyType":23,"phases":170,"briefSummary":171,"conditions":172,"keywords":174,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":188,"leadSponsor":189,"locationsCount":49},"100649874","body-based-and-mind-based-regulation-in-overweight-and-obese-women-100649874","NCT07738263","Body-Based and Mind-Based Regulation in Overweight and Obese Women","Effects of Body-Based and Mind-Based Regulation Approaches on Heart Rate Variability, Emotional Eating, and Psychological Indicators in Overweight and Obese Women: An Evaluator-Blinded Randomized Trial","Inclusion Criteria:\n\n* Female participants.\n* Age between 18 and 60 years.\n* Body mass index (BMI) between 27.0 and 39.9 kg\u002Fm².\n* No regular participation in yoga, meditation, breathing exercises, structured relaxation programs, or similar mind-body practices within the previous 3 months.\n* No initiation of a structured weight-loss program within the previous 3 months.\n* Able to attend weekly intervention sessions, modules, and study assessments.\n* Willing to refrain from starting any new exercise, yoga, meditation, diet, or weight-loss program during the study.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* BMI ≥40 kg\u002Fm².\n* Uncontrolled hypertension or severe cardiovascular disease.\n* Cardiac arrhythmia, pacemaker, or other cardiac conditions that may affect heart rate variability (HRV).\n* Regular use of beta-blockers, antiarrhythmic agents, or other medications that substantially affect HRV (including medications affecting heart rate\u002Frhythm, anticholinergic drugs, tricyclic antidepressants, and stimulant\u002Fsympathomimetic medications).\n* Neurological disease.\n* Uncontrolled thyroid disease or uncontrolled metabolic\u002Fendocrine disorders.\n* Pregnancy or breastfeeding.\n* History of bariatric surgery.\n* Initiation of weight-loss medication or GLP-1 receptor agonist therapy within the previous 6 months.\n* Current or clinically diagnosed anorexia nervosa, bulimia nervosa, binge eating disorder, or other eating disorders requiring active treatment (emotional eating alone is not an exclusion criterion).\n* Psychological or psychiatric conditions that would interfere with safe participation.\n* Diagnosed obstructive sleep apnea or untreated severe sleep disorders.\n* Regular tobacco or nicotine product use within the previous 3 months.\n* Musculoskeletal conditions preventing participation in the intervention.\n* Cardiopulmonary or orthopedic limitations that make exercise unsafe.",{"count":169,"type":22},30,[25],"This study will compare two regulation-based approaches in women with overweight or obesity. The first approach is a body-based regulation program including breathing awareness, body-awareness-based yoga practices, non-invasive manual auricular stimulation, and restorative relaxation. The second approach is a mind-based regulation program including structured psychoeducation and cognitive-emotional awareness activities focused on stress, emotions, automatic thoughts, and emotional eating.\n\nParticipants will be women aged 18 to 60 years with a body mass index between 27.0 and 39.9 kg\u002Fm². Eligible participants will be randomly assigned to one of the two intervention groups. Both programs will last 8 weeks.\n\nThe main aim of the study is to examine and compare the preliminary effects of these two approaches on heart rate variability, especially RMSSD, which is an indicator of cardiac vagal regulation. The study will also assess emotional eating, self-compassion, mindfulness, body measurements, body composition, adherence to the program, and possible adverse events. Assessments will be performed at baseline and after the 8-week intervention by an evaluator who is blinded to group allocation.",[173],"Overweight and\u002For Obesity",[175,176,177,178,179,180,181,182,183,184],"obesity","overweight","Heart Rate Variability","Emotional Eating","Body-Based Regulation","Mind-Based Regulation","Autonomic Nervous System","Psychological Well-Being","women","Randomized Controlled Trial",{"date":186,"type":41},"2026-07-31",{"date":157,"type":22},{"date":159,"type":22},{"name":47,"class":48},{"id":191,"slug":192,"hasResults":12,"nctId":193,"briefTitle":194,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":12,"sex":84,"minAge":57,"maxAge":4,"enrollmentInfo":196,"targetDuration":4,"studyType":23,"phases":198,"briefSummary":199,"conditions":200,"keywords":202,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":213,"locationsCount":49},"100621153","comparison-of-the-efficacy-of-perineal-and-intravaginal-electrical-stimulation-in-women-with-idiopathic-overactive-bladder-100621153","NCT07366918","Comparison of the Efficacy of Perineal and Intravaginal Electrical Stimulation in Women With Idiopathic Overactive Bladder","Inclusion Criteria:\n\n* Women over the age of 18 with a clinical diagnosis of idiopathic OAB\n* Intolerant or unresponsive to antimuscarinic or oral β3 adrenoceptor agonist (mirabegron) medications and not using them for at least 4 weeks\n* Ability to understand the procedures, advantages, and potential side effects\n* Ability to provide written, informed consent\n* Pelvic floor muscle (PFM) strength of 3\u002F5 or higher (modified Oxford scale, minimum: 0 - maximum: 5)\n\nExclusion Criteria:\n\n* Women with pure stress urinary incontinence\n* History of conservative treatment for OAB within the last 6 months (MI, IVES, perineal ES, etc.)\n* Pregnant or planning to become pregnant at the time of the study\n* Diagnosis of vaginal infection, urinary tract infection, or cancer\n* Women with urinary incontinence within the last 3 months Those who have undergone urogynecological surgery\n* Those with genital area disorders that may preclude the use of a vaginal probe or perineal electrode\n* Those diagnosed with stage 2 or higher according to the Pelvic Organ Prolapse Assessment (POP-Q)\n* Those with a pacemaker or implanted defibrillator\n* Those with neurogenic bladder or a history of neurological disease\n* Those with a urine residual of more than 100 ml detected by ultrasound (using an ultrasound device)\n* Those with allergies to condoms or lubricating gels used with a vaginal probe or perineometer",{"count":197,"type":22},63,[25],"The investigators conducted a prospective, randomized double-blind, placebo-controlled study based on a placebo technique to evaluate the efficacy of IVES vs perineal ES in women with idiopathic OAB.\n\nThe main questions aimed to be answered are:\n\nIs Intravaginal Electrical Stimulation (IVES) or perineal ES more effective on clinical parameters related to incontinence and quality of life in women with idiopathic overactive bladder (OAB)? Participants (n:63) with idiopathic OAB who meet the exclusion and inclusion criteria will be divided into 3 groups using a randomization table. The first group will receive IVES and bladder training (n:21), second group will receive perineal ES and bladder training (n:21) and third group will receive bladder training (n=21) . Measurements will be performed twice in total, before and at the end of treatment (8th week).",[201],"Urinary Bladder, Overactive",[203,118,204,205],"Idiopathic overactive bladder","perineal electrical stimulation","Intravaginal electrical stimulation","2026-07-27",{"date":208,"type":41},"2026-07-29",{"date":210,"type":41},"2025-12-01",{"date":212,"type":22},"2027-01-01",{"name":47,"class":48},{"id":215,"slug":216,"hasResults":12,"nctId":217,"briefTitle":218,"officialTitle":218,"acronym":4,"eligibilityCriteria":219,"healthyVolunteers":12,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":220,"targetDuration":4,"studyType":23,"phases":222,"briefSummary":223,"conditions":224,"keywords":226,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":229,"lastUpdatePostDateStruct":230,"startDateStruct":232,"completionDateStruct":234,"leadSponsor":236,"locationsCount":49},"100455794","intracochlear-platelet-rich-fibrin-application-in-cochlear-implantation-100455794","NCT05215197","Intracochlear Platelet-rich Fibrin Application in Cochlear Implantation","Inclusion Criteria:\n\n* Patients with sensorineural hearing loss\n* Patients who will have cochlear implant surgery with CI422 electrode\n\nExclusion Criteria:\n\n* Patients with cochlear abnormality\n* Patients with auditory neuropathy",{"count":221,"type":22},10,[25],"Fibrosis due to surgical trauma is a common problem with cochlear implants. Fibrosis limits the effectiveness of implant and increases the power consumption. Our aim in this study is to benefit from the anti-inflammatory effects of autologous platelet-rich fibrin to reducing the fibrotic cascade.",[225],"Hearing Loss, Sensorineural",[227,228],"cochlear implant","platelet rich fibrin","2026-07-12",{"date":231,"type":41},"2026-07-14",{"date":233,"type":41},"2022-01-31",{"date":235,"type":22},"2028-12-20",{"name":47,"class":48},{"id":238,"slug":239,"hasResults":12,"nctId":240,"briefTitle":241,"officialTitle":241,"acronym":4,"eligibilityCriteria":242,"healthyVolunteers":83,"sex":84,"minAge":243,"maxAge":57,"enrollmentInfo":244,"targetDuration":4,"studyType":23,"phases":246,"briefSummary":247,"conditions":248,"keywords":252,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":259,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":49},"100647179","impact-of-plyometric-training-methods-on-athletic-performance-and-detraining-processes-in-youth-female-soccer-players-100647179","NCT07705087","Impact of Plyometric Training Methods on Athletic Performance and Detraining Processes in Youth Female Soccer Players","Inclusion Criteria:\n\n* No history of surgery due to musculoskeletal injuries within the past 6 months.\n* No use of ergogenic supplements within the past 3 months.\n* Regular participation in routine team training sessions for at least 2 months prior to the study.\n\nExclusion Criteria:\n\n* History of any recent injury requiring a recovery period of more than one week.\n* Use of ergogenic aids or nutritional supplements during the intervention period.\n* Missing two consecutive or four non-consecutive training sessions during the study period.\n* Participation in additional structured physical training or exercises outside of the routine team practices and the study protocol.","13 Years",{"count":245,"type":22},36,[25],"Lower extremity strength, explosive power, dynamic balance, and functional range of motion are critical determinants of athletic performance and injury prevention in soccer (football). While plyometric training is widely used to improve these qualities, the comparative effects of bodyweight plyometric training versus externally loaded plyometric training, and the maintenance of these effects during detraining periods, remain unclear. This study aims to investigate the effects of two different plyometric training methods on athletic performance and subsequent detraining processes in young female soccer players. Participants will be randomly assigned to three groups: Bodyweight Plyometric Training Group (BW-PT), External Loading Plyometric Training Group (EL-PT, who will wear vests weighing 10% of their body weight), and Control Group (CG, who will only continue with routine soccer training). Training interventions will be conducted for 6 weeks, immediately followed by a 4-week detraining period. To comprehensively assess athletic performance, the following measurements will be taken at baseline (pre-test), immediately after the training period (post-test), and after the detraining period (maintenance test): Isokinetic muscle strength of knee extensors and flexors (peak torque and force development rate at 60°\u002Fs and 120°\u002Fs), Jumping performance (standing long jump, vertical jump height, and 15-second repeated jump test), Functional range of motion (via Functional Movement Screen - FMS), Dynamic balance (via Y-Balance Test). The primary objective is to determine which plyometric loading strategy, compared to traditional soccer training, provides superior and longer-lasting physiological and biomechanical adaptations in young female athletes.",[249,250,251],"Healthy","Athletic Performance","Detraining",[253,254,255,256,257],"Plyometric training","Female football players","Isokinetic strength","Jump performance","Neuromuscular control","2026-07-10",{"date":260,"type":41},"2026-07-15",{"date":262,"type":22},"2026-07-20",{"date":264,"type":22},"2026-10-19",{"name":47,"class":48},{"id":267,"slug":268,"hasResults":12,"nctId":269,"briefTitle":270,"officialTitle":271,"acronym":4,"eligibilityCriteria":272,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":273,"targetDuration":4,"studyType":23,"phases":274,"briefSummary":275,"conditions":276,"keywords":279,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":285,"startDateStruct":286,"completionDateStruct":287,"leadSponsor":288,"locationsCount":49},"100647172","kinesio-taping-for-neurogenic-bowel-dysfunction-in-spinal-cord-injury-100647172","NCT07705984","Kinesio Taping for Neurogenic Bowel Dysfunction in Spinal Cord Injury","Effectiveness of Kinesio Taping on Neurogenic Bowel Dysfunction in Individuals With Spinal Cord Injury: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18 years or older with traumatic or nontraumatic spinal cord injury\n* Neurological level of injury at T12 or above\n* Upper motor neuron-type neurogenic bowel dysfunction\n* Duration of spinal cord injury longer than 6 months\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Age younger than 18 years\n* Neurological level of injury below T12\n* Gastrointestinal disease diagnosed before the spinal cord injury, including irritable bowel syndrome or inflammatory bowel disease\n* History of conservative treatment for neurogenic bowel dysfunction within the previous 6 months\n* Colostomy or history of bowel surgery\n* Neurological disease other than spinal cord injury that may cause gastrointestinal or anal sphincter dysfunction\n* Cognitive impairment that may interfere with participation in the study",{"count":169,"type":22},[25],"Neurogenic bowel dysfunction is a common complication of spinal cord injury and may cause constipation, difficulty with defecation, prolonged bowel care, incomplete evacuation, fecal incontinence, and reduced quality of life. This randomized controlled trial aims to evaluate the effectiveness of Kinesio Taping added to a routine bowel management program in adults with spinal cord injury and upper motor neuron-type neurogenic bowel dysfunction.\n\nThirty participants will be randomly assigned to one of two parallel groups. The control group will receive a routine bowel management program, while the intervention group will receive Kinesio Taping in addition to the routine bowel management program. Kinesio Taping will be applied to the lower abdominal and lumbosacral regions three times per week for 4 weeks.\n\nThe primary outcome will be defecation frequency recorded using a 7-day bowel diary. Secondary outcomes will include stool consistency, defecation duration, perceived constipation severity, neurogenic bowel dysfunction severity, and health-related quality of life. Assessments will be performed before and after the 4-week intervention.",[277,278],"Neurogenic Bowel Dysfunction","Spinal Cord Injury",[280,281,282,283,284],"Kinesio Taping","Neurogenic Bowel","Constipation","Bowel Management","Spinal Cord Injury Rehabilitation",{"date":260,"type":41},{"date":153,"type":22},{"date":45,"type":22},{"name":47,"class":48},{"id":290,"slug":291,"hasResults":12,"nctId":292,"briefTitle":293,"officialTitle":294,"acronym":295,"eligibilityCriteria":296,"healthyVolunteers":83,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":297,"targetDuration":4,"studyType":23,"phases":299,"briefSummary":300,"conditions":301,"keywords":304,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":308,"startDateStruct":309,"completionDateStruct":311,"leadSponsor":313,"locationsCount":4},"100647095","otago-exercises-in-diabetes-mellitus-examining-its-effectiveness-100647095","NCT07705958","OTAGO Exercises in Diabetes Mellitus Examining Its Effectiveness","OTAGO Exercises in Individuals Diagnosed With Diabetes Mellitus Examining Its Effectiveness","OTAGO in DM","Inclusion Criteria:\n\n* Cases diagnosed with Diabetes Mellitus,\n* Cases that do not have any orthopedic\u002Fneurological\u002Fcardiopulmonary disease other than Diabetes Mellitus that will directly affect the evaluation results,\n* Having agreed to participate in the study voluntarily,\n* Having been diagnosed with Type 2 DM for at least 1 year\n\nExclusion Criteria:\n\n* Not agreeing to participate in the study,\n* Individuals with additional diseases other than DM that will affect the evaluations,\n* Having a smoking habit or history\n* Restriction in joint movements or any orthopedic\u002Fneurological\u002Fcardiopulmonary disease that may cause this,\n* Not being able to cooperate,\n* Having vision loss,\n* Having hearing loss,\n* Having a diabetic ulcer on the foot,",{"count":298,"type":22},56,[25],"Diabetes Mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia, which occurs in insulin deficiency or when the body cannot effectively use the insulin produced. Moreover, according to the \"Global Report on Diabetes\" data published by the World Health Organization (WHO) in 2016, it is an important public health problem, one of the four priority non-communicable diseases (1, 2). In addition to the high mortality rates caused by complications due to DM, it is also known that it can cause low quality of life and many other additional problems in individuals. Possible complications are chronic and serious problems such as heart attack, risk of stroke, kidney failure, vision loss and nerve damage. One of the most common and most disabling complications is neuropathy. It should also be noted that approximately half of diabetic neuropathy is asymptomatic and patients diagnosed with DM may have neuropathy due to causes other than diabetes (2). These complications and damage that DM can cause can lead to decreased blood flow combined with neuropathy; As a result, foot ulcers and infections may occur; Amputation rates may increase. In addition to such additional complications that diabetic neuropathy may cause, due to all these; Loss of protective plantar sensation may also occur (3). This loss of protective sensation may lead to cutaneous deficits in the lower extremities, loss of muscle strength and reflexes, and gait and balance disorders (4). The mechanism that makes an important contribution to functional joint stability and the continuity of this stability, along with the feedback mechanisms required to ensure neuromuscular control, is proprioception, which includes joint movement (kinesthesia) and joint position sense (EPH) and is a subunit of the somatosensory system (5-7). . Rehabilitation with various injuries and other clinical conditions; Clinical studies to determine its effects on joint proprioception, neuromuscular control and balance have mostly focused on knee and ankle joints (5). The main reason for this can be attributed to the great importance of the knee and ankle joints in the lower extremities in maintaining general body kinematics and balance (8). Additionally, it has been reported in the literature that EPH and plantar sensory loss are observed in individuals diagnosed with DM, and these complications may cause additional problems (10, 12, 18-22). Additionally, many studies in the literature on this subject have been conducted in individuals with diabetic neuropathy, and changes in functional parameters such as plantar sensation, proprioception, muscle strength and balance have been examined (10, 19, 20, 22, 23). However, it has been found that not only individuals with neuropathy but also individuals diagnosed with DM without neuropathy have balance disorders (24).\n\nThere are many studies in the literature about the effects of different exercise training on proprioception. In general, studies have reported that exercise training without weight bearing on the extremity has no effect on proprioception, but as a result of exercises performed with weight bearing on the extremity, a significant improvement was noted in both proprioceptive performance and muscle strength (25). In one of the most recent studies on this subject, it was stated that proprioceptive sensitivity increased in individuals with knee osteoarthritis with 8-week squat strengthening training performed by transferring weight to the extremity (26). Additionally, there are studies in the literature reporting different results regarding the effects of stretching exercises on proprioceptive performance. Some studies have reported that static stretching has no effect on proprioception, while others have reported that it has a positive effect on proprioception (27,28).\n\nThe Otago Exercise Program is an evidence-based, home-based, individually tailored strength and balance retraining program. Research shows that the Otago Exercise Program is effective in reducing the risk of death and the incidence of falls in older adults over a one-year period. In one study, falls were reduced by 35% in older adults has been reported(29)\n\nThis study was planned to examine the effectiveness of balance exercises given as a home program to individuals diagnosed with Type 2 DM.",[302,303],"Diabetes Mellitus","Balance",[305,306,307],"balance","otago exercise","Diabetes mellitus",{"date":260,"type":41},{"date":310,"type":22},"2026-08-01",{"date":312,"type":22},"2026-12-01",{"name":47,"class":48},{"id":315,"slug":316,"hasResults":12,"nctId":317,"briefTitle":318,"officialTitle":319,"acronym":4,"eligibilityCriteria":320,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":321,"targetDuration":323,"studyType":324,"phases":4,"briefSummary":325,"conditions":326,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":328,"lastUpdatePostDateStruct":329,"startDateStruct":331,"completionDateStruct":333,"leadSponsor":335,"locationsCount":49},"100645835","the-kings-brief-lnterstitial-lung-disease-questionnaire-100645835","NCT07700004","The King's Brief Lnterstitial Lung Disease Questionnaire","Investigation of the Turkish Validity and Reliability of The King's Brief Interstitial Lung Disease Questionnaire (K-BILD) in Individuals With Interstitial Lung Involvement Secondary to Rheumatological Diseases","Inclusion Criteria:-Having been diagnosed with interstitial lung disease by a rheumatologist,\n\n* Being 18 years of age or older,\n* Agreeing to participate in the study.\n\nExclusion Criteria:- Presence of a neurological disease\n\n* Presence of any orthopedic problem that affects functionality\n* History of any orthopedic surgery in the last year\n* Inability to speak or understand Turkish fluently\n* Presence of a psychiatric illness that affects cooperation\n* Heart failure that affects daily living activities\n* Being a cancer patient",{"count":322,"type":22},45,"1 Day","OBSERVATIONAL","The aim of this study is to examine the validity and reliability of the Turkish Validity and Reliability of The King's Brief Interstitial Lung Disease Questionnaire (K-BILD) in Individuals with Interstitial Lung Involvement Secondary to Rheumatological Diseases.",[327],"Interstitial Lung Disease Due to Systemic Disease","2026-07-07",{"date":330,"type":41},"2026-07-13",{"date":332,"type":22},"2026-07-05",{"date":334,"type":22},"2027-05-15",{"name":47,"class":48},{"id":337,"slug":338,"hasResults":12,"nctId":339,"briefTitle":340,"officialTitle":341,"acronym":4,"eligibilityCriteria":342,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":343,"enrollmentInfo":344,"targetDuration":4,"studyType":23,"phases":345,"briefSummary":346,"conditions":347,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":353,"lastUpdatePostDateStruct":354,"startDateStruct":355,"completionDateStruct":356,"leadSponsor":358,"locationsCount":49},"100646228","extracorporeal-shock-wave-therapy-in-botulinum-toxin-treated-patients-with-post-stroke-ankle-plantar-flexor-spasticity-100646228","NCT07695038","Extracorporeal Shock Wave Therapy in Botulinum Toxin-Treated Patients With Post-Stroke Ankle Plantar Flexor Spasticity","Effectiveness of Extracorporeal Shock Wave Therapy as an Adjunct to Botulinum Toxin Injection in Patients With Post-Stroke Ankle Plantar Flexor Spasticity: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of stroke according to the World Health Organization (WHO) (1989) definition.\n* Stroke diagnosis confirmed by magnetic resonance imaging (MRI).\n* Patients aged between 18 and 65 years.\n* Clinically stable condition after stroke.\n* Patients who have undergone routine Botulinum Toxin Type A (BoNT-A) injection to the gastrocnemius muscle.\n* Presence of ankle plantar flexor spasticity with a Modified Ashworth Scale (MAS) score of greater than or equal to 1 (MAS ≥ 1).\n\nExclusion Criteria:\n\n* Presence of fixed contracture at the ankle joint.\n* History of prior antispastic surgical procedures.\n* Changes in antispastic medication dosage or type within the last 6 months.\n* Active infection or malignancy at the application site.\n* Presence of a cardiac pacemaker.\n* Bleeding disorders or advanced vascular disease.\n* Pregnancy.\n* Presence of neuromuscular junction disease or motor neuron disease.\n* Known allergy or hypersensitivity to Botulinum Toxin Type A.\n* Current use of antibiotics.","65 Years",{"count":60,"type":22},[25],"The goal of this clinical trial is to learn if radial Extracorporeal Shock Wave Therapy (rESWT) is effective in reducing ankle plantar flexor spasticity and improving walking functions in stroke patients who have already received Botulinum Toxin type A (BoNT-A) injections. The main questions it aims to answer are:\n\n* Does adding rESWT to standard physical therapy significantly lower muscle spasticity in patients who have received BoNT-A, compared to receiving physical therapy alone after the injection?\n* Does combining rESWT with BoNT-A injection improve functional walking parameters (such as gait speed, cadence, and step length) and daily life independence more than the BoNT-A and physical therapy combination alone?\n* Can rESWT induce additional structural and flexibility improvements in the BoNT-A injected gastrocnemius muscle, as measured objectively by ultrasound imaging and strain elastography?\n\nResearchers will compare a group of participants receiving both rESWT and conventional physical therapy (Group 1) to a comparison group receiving only conventional physical therapy (Group 2) to see if rESWT provides additional clinical benefits. All participants in both groups will have already undergone routine BoNT-A injections one week prior to starting the study treatments.\n\nParticipants will:\n\n* Undergo a 3-week conventional physical therapy and rehabilitation program, consisting of 2 to 3 hours of therapy per day, 5 days a week.\n* Receive 3 weekly sessions of rESWT (2000 pulses per session applied to the calf muscles) if they are randomized into the rESWT group.\n* Attend clinical evaluation visits and objective assessment sessions-including high-tech computerized gait analysis and specialized musculoskeletal ultrasound imaging-before the treatment, at the end of the 3rd week, and at a 12-week follow-up.",[348,349,350,351,352],"Stroke","Post-stroke Spasticity of the Lower Limb","Post-Stroke Spasticity","Spasticity of the Plantar Flexors","Spasticity, Post-Stroke","2026-07-04",{"date":258,"type":41},{"date":262,"type":22},{"date":357,"type":22},"2027-08-20",{"name":47,"class":48},{"id":360,"slug":361,"hasResults":12,"nctId":362,"briefTitle":363,"officialTitle":364,"acronym":4,"eligibilityCriteria":365,"healthyVolunteers":12,"sex":84,"minAge":57,"maxAge":85,"enrollmentInfo":366,"targetDuration":4,"studyType":23,"phases":367,"briefSummary":368,"conditions":369,"keywords":371,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":376,"lastUpdatePostDateStruct":377,"startDateStruct":379,"completionDateStruct":380,"leadSponsor":382,"locationsCount":49},"100642780","connective-tissue-massage-and-music-based-progressive-muscle-relaxation-in-primary-dysmenorrhea-100642780","NCT07647276","Connective Tissue Massage and Music-Based Progressive Muscle Relaxation in Primary Dysmenorrhea","The Effects of Connective Tissue Massage and Music-Based Progressive Muscle Relaxation on Pain Intensity, Pressure Pain Threshold, and Menstruation-Related Symptoms in Women With Primary Dysmenorrhea: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Having a diagnosis of primary dysmenorrhea made by a Gynecology and Obstetrics specialist\n* Being between 18-30 years of age\n* Being nulliparous\n* Having a regular menstrual cycle (28 ± 7 days)\n* Having menstrual pain intensity greater than 4 cm on the Visual Analog Scale for the last 6 months\n* Voluntarily agreeing to participate in the study\n\nExclusion Criteria:\n\n* Having been diagnosed at least 6 months prior with gastrointestinal, urogynecological, autoimmune, or psychiatric diseases and\u002For chronic pain syndromes\n* Having any neurological or systemic disease\n* Having a history of childbirth or previous pregnancy\n* Being pregnant\n* Using an intrauterine device (IUD)\n* Having any pelvic pathology or history of pelvic surgery\n* Chronic use of medications, including oral contraceptives or antidepressants\n* Currently receiving anti-inflammatory, analgesic, or psychotherapeutic drug treatment\n* Having irregular menstrual cycles (\\\u003C21 or \\>35 days and\u002For cycle variation \\>4 days)\n* Presence of pathology indicating secondary dysmenorrhea",{"count":245,"type":22},[25],"This randomized controlled clinical trial aims to investigate the effects of Connective Tissue Massage (CTM) and music-based Progressive Muscle Relaxation Training (PMRT) on pain intensity, pressure pain threshold, analgesic use, and menstruation-related symptoms in women with primary dysmenorrhea. Participants will be randomly assigned to one of three groups: CTM, music-based PMRT, or control. Baseline assessment will be conducted during menstrual days 1-2 of Cycle 0. The interventions will be applied during the premenstrual intervention window of Cycle 0, from the estimated ovulation day, calculated as cycle length minus 14 days, until Cycle 1 Day 1. Post-intervention assessment will be conducted during menstrual days 1-2 of Cycle 1. No intervention will be applied after the post-intervention assessment, and follow-up assessment will be conducted during menstrual days 1-2 of Cycle 2. Outcomes including pain intensity, pressure pain threshold, analgesic use, menstrual symptoms, attitudes toward menstruation, functional and emotional impact of dysmenorrhea, and pain catastrophizing will be evaluated across menstrual cycles. Participant satisfaction and adherence to the interventions will also be assessed.",[370],"Primary Dysmenorrhea",[372,373,374,375],"Primary dysmenorrhea","Connective tissue massage","Progressive muscle relaxation training","Pain","2026-06-26",{"date":378,"type":41},"2026-06-30",{"date":97,"type":41},{"date":381,"type":22},"2026-11-15",{"name":47,"class":48},{"id":384,"slug":385,"hasResults":12,"nctId":386,"briefTitle":387,"officialTitle":388,"acronym":4,"eligibilityCriteria":389,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":390,"targetDuration":4,"studyType":23,"phases":391,"briefSummary":392,"conditions":393,"keywords":395,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":400,"lastUpdatePostDateStruct":401,"startDateStruct":402,"completionDateStruct":403,"leadSponsor":405,"locationsCount":49},"100642023","comparison-of-the-effects-of-two-different-exercise-programs-on-femoral-cartilage-thickness-and-clinical-parameters-in-individuals-with-knee-osteoarthritis-100642023","NCT07657481","Comparison of the Effects of Two Different Exercise Programs on Femoral Cartilage Thickness and Clinical Parameters in Individuals With Knee Osteoarthritis","Comparison of the Effects of Two Different Home Exercise Programs on Femoral Cartilage Thickness and Clinical Parameters in Individuals With Knee Osteoarthritis: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age ≥18 years\n2. Diagnosis of knee osteoarthritis according to ACR criteria, Kellgren-Lawrence grade 2-3\n3. Knee pain for at least 3 months\n4. Having the physical capacity to perform a home exercise program\n5. Willingness to provide written informed consent\n\nExclusion Criteria:\n\n1. History of knee, hip, or spine surgery\n2. Active inflammatory arthritis (e.g., rheumatoid arthritis, gout, psoriatic arthritis)\n3. Intra-articular injection within the last 3 months\n4. Neurological or neuromuscular disorders\n5. Body mass index (BMI) \\> 40 kg\u002Fm²\n6. Pregnancy\n7. Cardiovascular or orthopedic contraindications preventing participation in a regular exercise program\n8. Cognitive impairment",{"count":298,"type":22},[25],"Knee osteoarthritis (OA) is one of the most common joint disorders worldwide and is a leading cause of pain, limited mobility, and functional disability, particularly in the elderly population. According to 2020 data, approximately 654 million individuals aged 40 years and older are affected by knee OA worldwide, with a global prevalence of 22.9% in this age group. In our country as well, OA is reported as the second most common rheumatologic disease. The disease not only negatively affects individuals' quality of life but also creates a significant socioeconomic burden through work loss, hospital admissions, and the need for surgical interventions.\n\nThe pathogenesis of knee OA is a complex process involving articular cartilage degeneration, subchondral bone sclerosis, synovial tissue proliferation, and osteophyte formation. Once cartilage damage begins, its capacity for spontaneous healing is extremely limited; therefore, early interventions aimed at slowing or halting disease progression are of critical importance. In this context, non-pharmacological interventions, particularly exercise programs that may contribute to maintaining cartilage integrity, are strongly recommended as first-line treatment options in current clinical guidelines.\n\nThe beneficial effects of exercise therapy on pain and function in patients with knee OA are well documented. However, the structural effects of exercise on femoral cartilage thickness have been relatively less investigated. Tuna et al. evaluated femoral cartilage thickness using ultrasonography in 40 patients with knee OA following a 12-week quadriceps strengthening program and reported statistically significant increases in cartilage thickness in the medial condyle, lateral condyle, and intercondylar region at 3 months. This pioneering study suggests that muscle strengthening programs may have not only symptomatic but also structural benefits. Similarly, Bozan et al. reported a strong positive correlation between quadriceps muscle thickness (rectus femoris + vastus intermedius) and femoral cartilage thickness, supporting the idea that muscle loss parallels cartilage degeneration. However, these studies focused exclusively on the quadriceps muscle, and the effects of hip musculature on femoral cartilage thickness have not been investigated. Recent biomechanical studies indicate that hip abductor and adductor muscles play a critical role in knee joint loading patterns.\n\nHip abductor muscles provide pelvic stability during gait and directly influence knee adduction moments. Weakness of the gluteus medius leads to contralateral pelvic drop, increasing medial compartment loading on the ipsilateral knee and accelerating medial tibiofemoral cartilage wear. Indeed, Segal et al., using data from the Multicenter Osteoarthritis Study (MOST), demonstrated via MRI that greater hip abductor strength significantly reduces the risk of progression of medial patellofemoral and lateral tibiofemoral cartilage damage. On the other hand, hip adductor muscles are also thought to contribute to knee adduction moments by eccentrically controlling femoral varus motion; however, this relationship has been studied far less compared to quadriceps and abductors.\n\nSystematic reviews and meta-analyses have shown that individuals with knee OA have up to 24% lower isometric hip abductor strength compared to healthy controls. Randomized controlled trials investigating combined hip and quadriceps strengthening programs have reported significant improvements in pain and function. However, none of these studies have used femoral cartilage thickness measured by ultrasonography as a primary outcome.\n\nA review of the current literature reveals that although studies exist examining the effects of quadriceps strengthening on femoral cartilage thickness, no randomized controlled trial has compared hip abductor and adductor strengthening exercises with a quadriceps strengthening program, using ultrasonographic femoral cartilage thickness as the primary outcome measure. This study aims to address this gap. All interventions will be applied as non-invasive home exercise programs, and all measurements will be performed using ultrasonography. Baseline, 1-month, and 3-month assessments will also allow evaluation of the temporal effects of exercise on cartilage structure. The findings are expected to provide scientific evidence regarding the structural protective effects of hip exercises in knee OA rehabilitation and serve as pilot data for future large-scale multicenter studies.\n\nThe aim of this study is to compare patients with knee OA receiving quadriceps strengthening exercises alone with those receiving additional hip abductor\u002Fadductor strengthening exercises in terms of changes in femoral cartilage thickness, and to evaluate whether there is a correlation between femoral cartilage thickness and the thickness of the rectus femoris, gluteus medius,",[394],"Osteo Arthritis of the Knee",[396,397,398,399],"knee osteoartritis","femoral cartilage thikness","quadriceps strengthening exercises","hip abductor and adductor strengthening exercises","2026-06-17",{"date":97,"type":41},{"date":40,"type":22},{"date":404,"type":22},"2027-07-01",{"name":47,"class":48},{"id":407,"slug":408,"hasResults":12,"nctId":409,"briefTitle":410,"officialTitle":411,"acronym":412,"eligibilityCriteria":413,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":414,"targetDuration":4,"studyType":324,"phases":4,"briefSummary":416,"conditions":417,"keywords":419,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":423,"lastUpdatePostDateStruct":424,"startDateStruct":425,"completionDateStruct":427,"leadSponsor":428,"locationsCount":49},"100641704","central-sensitization-and-functional-outcomes-in-chronic-shoulder-pain-100641704","NCT07654023","Central Sensitization and Functional Outcomes in Chronic Shoulder Pain","The Effects of Central Sensitization and Psychological Factors on Functional Outcomes Following Rehabilitation in Individuals With Chronic Shoulder Pain","SHOULDER-CS","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Presence of chronic shoulder pain lasting at least 3 months\n* Clinical findings consistent with shoulder-related pain\n* Willingness to participate in a 6-week physiotherapy rehabilitation program\n* Ability to complete study assessments and questionnaires\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* History of shoulder surgery within the previous 6 months\n* Major shoulder trauma within the previous 6 months\n* Serious pathology affecting the shoulder (e.g., infection, tumor, systemic inflammatory disease)\n* Neurological disorders affecting the upper extremity (e.g., cervical radiculopathy, myelopathy, peripheral nerve injury)\n* Severe cognitive impairment\n* Communication problems preventing participation\n* Shoulder injection within the previous 4 weeks\n* Pregnancy",{"count":415,"type":22},59,"This prospective observational cohort study aims to investigate whether baseline central sensitization and psychological factors predict functional outcomes following rehabilitation in individuals with chronic shoulder pain. Participants with chronic shoulder pain will receive a standardized 6-week physiotherapy and rehabilitation program routinely applied in the clinic. Assessments will be performed before and after treatment, including pain severity, shoulder function, central sensitization symptoms, and psychological factors such as pain catastrophizing. The findings of this study may contribute to a better understanding of biopsychosocial factors affecting rehabilitation outcomes in chronic shoulder pain and help improve individualized rehabilitation approaches.",[418],"Chronic Shoulder Pain",[420,421,422],"Chronic shoulder pain","Central sensitization","Physical therapy","2026-06-13",{"date":400,"type":41},{"date":426,"type":22},"2026-06-15",{"date":310,"type":22},{"name":47,"class":48},{"id":430,"slug":431,"hasResults":12,"nctId":432,"briefTitle":433,"officialTitle":434,"acronym":4,"eligibilityCriteria":435,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":343,"enrollmentInfo":436,"targetDuration":4,"studyType":23,"phases":437,"briefSummary":438,"conditions":439,"keywords":442,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":446,"lastUpdatePostDateStruct":447,"startDateStruct":449,"completionDateStruct":451,"leadSponsor":453,"locationsCount":49},"100636558","the-effect-of-kinesio-taping-on-hand-functions-in-zone-v-vi-extensor-tendon-injuries-100636558","NCT07567248","The Effect of Kinesio Taping on Hand Functions in Zone V-VI Extensor Tendon Injuries","Investigation of the Effect of Kinesio Taping on Hand Functions in Zone V-VI Extensor Tendon Injuries: A Double-Blind Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Aged between 18 and 65 years\n* Having an isolated Zone V-VI extensor tendon injury\n* Having undergone primary treatment for the injury\n\nExclusion Criteria:\n\n* History of prior surgery on the affected extremity\n* Presence of accompanying neurological, orthopedic, rheumatologic, or metabolic disease in the affected extremity\n* Presence of flexor tendon injury\n* Presence of fractures of the metacarpals, carpal bones, or radius\u002Fulna\n* Presence of an open incision line\n* Delayed wound healing\n* Presence of peripheral nerve injury\n* Presence of replantation or amputation",{"count":245,"type":22},[25],"This study aims to investigate the effects of Kinesio Taping (KT) on hand function in patients with Zone V-VI Extensor Digitorum Communis (EDC) tendon injuries following primary repair. Extensor tendon injuries in this region often lead to complications such as adhesion formation, reduced range of motion, extensor lag, and impaired hand function, despite standard rehabilitation approaches. Therefore, additional interventions that may enhance tendon gliding and neuromuscular control are of clinical interest.\n\nIn this double-blind randomized controlled trial, patients will be assigned to either a KT group or a sham taping control group. Both groups will receive a standardized postoperative rehabilitation program, while the intervention group will additionally receive KT applications between postoperative weeks 6 and 12. Outcome measures, including range of motion, grip and pinch strength, and functional hand performance, will be assessed at 12 and 24 weeks.\n\nThe study seeks to determine whether KT provides additional benefits beyond conventional rehabilitation in improving functional recovery after extensor tendon injuries, addressing an important gap in the current literature.",[440,441],"Extensor Tendons of Finger Anomalies","Tendon Injuries",[443,444,445],"Extensor tendon","Functional recovery","Extensor lag","2026-04-28",{"date":448,"type":41},"2026-05-05",{"date":450,"type":22},"2026-05-07",{"date":452,"type":22},"2027-06-07",{"name":47,"class":48},{"id":455,"slug":456,"hasResults":12,"nctId":457,"briefTitle":458,"officialTitle":459,"acronym":4,"eligibilityCriteria":460,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":343,"enrollmentInfo":461,"targetDuration":4,"studyType":23,"phases":463,"briefSummary":464,"conditions":465,"keywords":469,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":474,"lastUpdatePostDateStruct":475,"startDateStruct":477,"completionDateStruct":479,"leadSponsor":481,"locationsCount":4},"100633885","emg-triggered-electrical-stimulation-after-medianulnar-nerve-repairs-100633885","NCT07532499","EMG-Triggered Electrical Stimulation After Median\u002FUlnar Nerve Repairs","The Impact of EMG-Triggered Electrical Stimulation of Extensor Muscles on Functional Status Following Median and\u002For Ulnar Nerve Repairs: A Single-Blind, Randomized Controlled Study","Inclusion Criteria:\n\n* Intact communication skills\n* No prior history of neurological, orthopedic, rheumatologic, or metabolic diseases affecting the involved extremity\n\nExclusion Criteria:\n\n* Presence of concomitant central nervous system involvement\n* Pregnancy\n* Patients with cardiac pacemakers\n* Patients with cardiac arrhythmias\n* Patients with epilepsy",{"count":462,"type":22},26,[25],"Immobilization following median and\u002For ulnar nerve repairs results in strength loss in the wrist and finger extensor muscles. Given the critical importance of wrist extension for functional grip, this condition significantly restricts hand functions. Therefore, this study aims to investigate the effects of EMG-triggered electrical stimulation applied to the wrist and finger extensors, in addition to conventional physiotherapy, on functional outcomes in patients undergoing median and\u002For ulnar nerve repair, with the objective of restoring extensor muscle weakness induced by immobilization.",[466,467,468],"Peripheral Nerve Injuries","Median Nerve Injury","Ulnar Nerve Injury",[470,471,472,473],"peripheral nerve injuries","EMG-triggered electrical stimulation","physiotherapy","functional recovery","2026-04-13",{"date":476,"type":41},"2026-04-16",{"date":478,"type":22},"2026-04-30",{"date":480,"type":22},"2027-11-30",{"name":47,"class":48},{"id":483,"slug":484,"hasResults":12,"nctId":485,"briefTitle":486,"officialTitle":487,"acronym":4,"eligibilityCriteria":488,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":343,"enrollmentInfo":489,"targetDuration":491,"studyType":324,"phases":4,"briefSummary":492,"conditions":493,"keywords":496,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":474,"lastUpdatePostDateStruct":500,"startDateStruct":502,"completionDateStruct":504,"leadSponsor":506,"locationsCount":49},"100622798","perceived-ability-and-hand-function-100622798","NCT07388303","Perceived Ability and Hand Function","The Relationship Between Perceived Manual Ability and Functional Measurements in Patients With Hand-Forearm Injuries","Inclusion Criteria:\n\n* Having sustained a hand and\u002For forearm injury and\u002For having undergone surgery related to this injury.\n* Being voluntary to participate in the study.\n\nExclusion Criteria:\n\n* Patients with concomitant central nervous system involvement.\n* Patients with a history of previous injury to the same extremity.\n* Patients with rheumatological disorders.",{"count":490,"type":22},34,"12 Weeks","Patient-reported outcome measures, which are subjective by nature, need to be correlated with clinician-administered professional measurements as a further step toward expanding their clinical utility. Therefore, this study aimed to investigate the relationship between perceived manual dexterity and functional measurements in patients with hand-forearm injuries.",[494,495],"Hand Injuries","Forearm Injuries",[497,498,499],"hand forearm injuries","perceived manual ability","functional measurements",{"date":501,"type":41},"2026-04-14",{"date":503,"type":41},"2025-01-06",{"date":505,"type":22},"2026-05-31",{"name":47,"class":48},{"id":508,"slug":509,"hasResults":12,"nctId":510,"briefTitle":511,"officialTitle":511,"acronym":4,"eligibilityCriteria":512,"healthyVolunteers":83,"sex":17,"minAge":343,"maxAge":4,"enrollmentInfo":513,"targetDuration":4,"studyType":324,"phases":4,"briefSummary":515,"conditions":516,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":518,"lastUpdatePostDateStruct":519,"startDateStruct":521,"completionDateStruct":523,"leadSponsor":525,"locationsCount":49},"100632930","predictors-of-climate-change-health-literacy-in-older-individuals-100632930","NCT07520084","Predictors of Climate Change Health Literacy in Older Individuals","Inclusion Criteria:- Being 65 years of age or older\n\n* Volunteering to participate in the study\n* Inclusion of elderly individuals who score 6 or higher on the Hodkinson Mental Test.\n\nExclusion Criteria:- older adults who cannot be contacted due to reasons such as Alzheimer's disease, dementia, or psychosis\n\n* Having another chronic illness that may cause pain (rheumatic diseases, hemiplegia, multiple sclerosis, diabetes, etc.)\n* Having a neurological disease (hemiplegia, Parkinson's, multiple sclerosis, vertigo, epilepsy, etc.)\n* Being blind\n* Having an orthopedic, neurological, or intellectual disability",{"count":514,"type":22},159,"The aim of this study is to identify predictors of climate change health literacy in older adults.",[517],"Older Adults (65 Years and Older)","2026-04-02",{"date":520,"type":41},"2026-04-09",{"date":522,"type":41},"2026-03-25",{"date":524,"type":22},"2026-09-15",{"name":47,"class":48},{"id":527,"slug":528,"hasResults":12,"nctId":529,"briefTitle":530,"officialTitle":531,"acronym":4,"eligibilityCriteria":532,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":343,"enrollmentInfo":533,"targetDuration":534,"studyType":324,"phases":4,"briefSummary":535,"conditions":536,"keywords":540,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":545,"lastUpdatePostDateStruct":546,"startDateStruct":548,"completionDateStruct":550,"leadSponsor":552,"locationsCount":553},"100615353","the-investigation-of-kinesiophobia-in-conservative-distal-radius-fractures-100615353","NCT07291505","The Investigation of Kinesiophobia in Conservative Distal Radius Fractures","Investigation of the Predictability of Kinesiophobia on Functional Outcomes in Conservatively Treated Distal Radius Fractures","Inclusion Criteria:\n\n* Having been treated conservatively with an isolated distal radius fracture diagnosis,\n* Having a cognitive level that allows one to understand assessment methods and apply instructions.\n\nExclusion Criteria:\n\n* Comorbid musculoskeletal-neurovascular injuries\n* Bilateral injuries",{"count":490,"type":22},"18 Weeks","This study aimed to investigate the predictability of kinesiophobia on functional outcomes in conservatively treated patients with distal radius fractures. For this purpose, patients' level of kinesiophobia will be assessed using the Tampa Kinesiophobia Scale. To assess the functional status of patients, joint range of motion and upper extremity weight bearing measurements will be performed. Patients' functionality will be additionally assessed with the Patient Rated Wrist Evaluation Questionnaire.",[537,538,539],"Distal Radius Fracture","Kinesiophobia","Functional Status",[541,542,543,544],"Tampa Scale of Kinesiophobia","distal radius fracture","wrist function","upper extremity weight bearing","2026-03-09",{"date":547,"type":41},"2026-03-10",{"date":549,"type":41},"2026-02-02",{"date":551,"type":22},"2026-12-30",{"name":47,"class":48},2,{"id":555,"slug":556,"hasResults":12,"nctId":557,"briefTitle":558,"officialTitle":559,"acronym":4,"eligibilityCriteria":560,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":343,"enrollmentInfo":561,"targetDuration":4,"studyType":324,"phases":4,"briefSummary":563,"conditions":564,"keywords":566,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":545,"lastUpdatePostDateStruct":569,"startDateStruct":571,"completionDateStruct":573,"leadSponsor":575,"locationsCount":553},"100615352","health-literacy-level-and-functional-outcomes-in-patients-with-hand-and-forearm-injuries-100615352","NCT07291492","Health Literacy Level and Functional Outcomes in Patients With Hand and Forearm Injuries","Examining the Relationship Between Health Literacy Level and Functional Outcomes in Patients With Hand and Forearm Injuries","Inclusion Criteria:\n\n* Aged 18-65 years\n* Voluntarily agreed to participate\n* Presented with hand and\u002For forearm injuries\n\nExclusion Criteria:\n\n* Concomitant shoulder or elbow injuries\n* History of surgery due to neurological, rheumatological, or metabolic conditions affecting the entire upper extremity\n* Employment in a health-related profession",{"count":562,"type":22},117,"The aim of this study is to examine the association between health literacy, patient-reported outcome measures, and grip strength in a cohort of patients with hand injuries.",[494,565],"Forearm Fractures",[567,568],"Health Literacy","Functional Outcomes",{"date":570,"type":41},"2026-03-11",{"date":572,"type":41},"2026-01-15",{"date":574,"type":22},"2026-03-23",{"name":47,"class":48},{"id":577,"slug":578,"hasResults":12,"nctId":579,"briefTitle":580,"officialTitle":581,"acronym":4,"eligibilityCriteria":582,"healthyVolunteers":12,"sex":84,"minAge":57,"maxAge":343,"enrollmentInfo":583,"targetDuration":4,"studyType":23,"phases":584,"briefSummary":585,"conditions":586,"keywords":589,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":593,"lastUpdatePostDateStruct":594,"startDateStruct":596,"completionDateStruct":598,"leadSponsor":599,"locationsCount":49},"100604786","comparison-of-ipc-therapy-as-an-alternative-or-an-adjunct-to-mld-within-cdt-for-bcrl-100604786","NCT07154043","Comparison of IPC Therapy as an Alternative or an Adjunct to MLD Within CDT for BCRL","Comparison of Intermittent Pneumatic Compression Therapy as an Alternative or an Adjunct to Manual Lymphatic Drainage Within Complete Decongestive Therapy for Breast Cancer-Related Lymphedema","Inclusion Criteria:\n\n* Female gender\n* Patients aged 18-65 years\n* Having a history of unilateral mastectomy and lymph node dissection at least one year ago due to breast cancer diagnosis.\n* Having unilateral breast cancer-related upper extremity lymphedema (\\>20% volume difference between the two upper extremities or \\>2 cm difference in circumference at any measured point) according to the diagnostic criteria of the International Society of Lymphology (Committee 2023) for at least six months.\n* Not having received lymphedema treatment or exercise therapy for the last six months\n* Completing breast cancer primary treatment at least 6 months ago (except hormone therapy\u002Faromatase inhibitors)\n\nExclusion Criteria:\n\n* Bilateral breast cancer\n* Bilateral axillary lymph node dissection\n* Metastatic breast cancer\n* Receiving ongoing radiotherapy or chemotherapy\n* Primary or bilateral lymphedema\n* Having active cancer\n* Presence of stage 3 lymphedema\n* Uncontrolled serious systemic disease (cardiopulmonary diseases, arterial or venous diseases, renal dysfunction, uncontrolled hypertension or hypotension, cardiac arrhythmia, scleroderma, Sudek's atrophy).\n* Current or recent (within the last 3 months) infection (cellulitis, lymphangitis) or deep venous thrombosis\n* Presence of open wounds\n* Using medications that may affect body fluid and electrolyte balance (diuretics, etc.).\n* Individuals with serious mental and sensory problems\n* Being pregnant\n* Body mass index \\>40 kg\u002Fm2",{"count":322,"type":22},[25],"Breast cancer is the most common cancer among women worldwide and lymphedema is one of its most significant complications. Breast cancer-related lymphedema (BCRL) may develop shortly after treatment or even years later, causing physical and psychological burden, functional impairment, and reduced quality of life. Complete decongestive therapy (CDT), which includes manual lymph drainage (MLD), compression, skin care, and exercise, is the standard approach. Intermittent pneumatic compression (IPC) has been proposed as an additional option, and current consensus reports emphasize the need for studies evaluating IPC in combination with MLD.\n\nPrevious studies comparing IPC and MLD, either alone or in combination, have shown inconsistent results. Some reported no significant difference between treatment groups, while others suggested additional benefits of IPC, particularly in reducing limb heaviness and tension. However, there is still insufficient evidence to clarify the exact role of IPC within CDT.\n\nThe aim of this study is to investigate the acute effects of using IPC instead of MLD, or in combination with MLD, on arm circumference, arm volume, shoulder range of motion, and quality of life in patients with BCRL.",[587,588],"Breast Cancer-Related Lymphedema","BCRL",[587,590,591,592],"Manual Lymph Drainage","Intermittent Pneumatic Compression","Complete Decongestive Therapy","2026-03-03",{"date":595,"type":41},"2026-03-04",{"date":597,"type":41},"2025-09-15",{"date":312,"type":22},{"name":47,"class":48},{"id":601,"slug":602,"hasResults":12,"nctId":603,"briefTitle":604,"officialTitle":605,"acronym":4,"eligibilityCriteria":606,"healthyVolunteers":83,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":607,"targetDuration":4,"studyType":23,"phases":608,"briefSummary":609,"conditions":610,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":615,"lastUpdatePostDateStruct":616,"startDateStruct":618,"completionDateStruct":620,"leadSponsor":622,"locationsCount":4},"100624126","the-effect-of-the-excellence-model-based-clinical-practice-preparation-program-on-students-100624126","NCT07405580","The Effect of the Excellence Model-Based Clinical Practice Preparation Program on Students","The Effect of a Preparation Program for Clinical Practice Based on the Excellence Model on Students' Readiness, Excellence, Clinical Comfort, and Anxiety Levels: A Randomized Controlled Trial","Inclusion criteria:\n\n* Being a nursing student,\n* Taking the Child Health and Nursing course for the first time,\n* Attending the course,\n* Not having previously taken pediatric nursing readiness training,\n* Agreeing to participate in the study voluntarily.\n\nExclusion criteria:\n\n* The student's refusal to participate in the study,\n* Withdrawal from the study before completing all stages of the research.",{"count":139,"type":22},[25],"Objective: This study was designed to develop a clinical practice preparation program based on the Pediatric Nursing Excellence Model for undergraduate nursing students and to evaluate the program's effect on students' readiness, clinical comfort and anxiety, and levels of excellence.\n\nMethod: This study is a pretest-posttest randomized controlled experimental study. The research is planned to be conducted with nursing students taking the Pediatric Health and Disease Nursing course. The study groups will consist of students who go out for clinical practice within the scope of this course. In the power analysis performed with the G\\*Power 3.1.9.7 program, the sample size was found to be 25 for the experimental group and 25 for the control group, for a total of 50. Research data will be collected using a questionnaire. The questionnaire consists of four sections containing the following questions: \"Student Descriptive Characteristics Information Form,\" \"Nursing Students' Readiness for Clinical Practice Scale,\" \"Pediatric Nursing Students' Clinical Comfort and Anxiety Instrument,\" and \"Pediatric Nursing Excellence (PHM) Model Questionnaire.\" In the study, students in the experimental group will receive routine orientation training and a clinical practice readiness program based on the excellence model. Students in the control group will only receive routine orientation training. Data analysis will be performed using the SPSS 20.0 software package.",[611,612,613,614],"Clinical Comfort and Worry","Readiness Levels for Clinical Practice","Pediatric Nursing Excellence Level","Nursing Student","2026-02-17",{"date":617,"type":41},"2026-02-19",{"date":619,"type":22},"2026-02-16",{"date":621,"type":22},"2027-06-30",{"name":47,"class":48},{"id":624,"slug":625,"hasResults":12,"nctId":626,"briefTitle":627,"officialTitle":628,"acronym":4,"eligibilityCriteria":629,"healthyVolunteers":12,"sex":17,"minAge":57,"maxAge":343,"enrollmentInfo":630,"targetDuration":632,"studyType":324,"phases":4,"briefSummary":633,"conditions":634,"keywords":636,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":641,"lastUpdatePostDateStruct":642,"startDateStruct":644,"completionDateStruct":646,"leadSponsor":648,"locationsCount":49},"100622799","functional-improvement-and-fine-dexterity-in-thumb-tendon-injuries-100622799","NCT07388316","Functional Improvement and Fine Dexterity in Thumb Tendon Injuries","Investigation of the Relationship Between Functional Improvement and Changes in Fine Manual Dexterity in Isolated Thumb Tendon Injuries","Inclusion Criteria:\n\n* No history of neurological, orthopaedic, rheumatological, metabolic disease or surgery in the relevant extremity\n\nExclusion Criteria:\n\n* Comorbid musculoskeletal-neurovascular injuries",{"count":631,"type":22},52,"24 Weeks","Considering the thumb's contribution to fine dexterity and precision grip, this study aims to evaluate fine manual dexterity alongside functional outcomes following isolated thumb tendon injuries, and to examine the relationship between postoperative functional improvement and changes in fine manual dexterity.",[635,441],"Thumb Injury",[637,638,639,640],"functional status","fine dexterity","thumb","tendon injury","2026-02-04",{"date":643,"type":41},"2026-02-06",{"date":645,"type":22},"2026-02-26",{"date":647,"type":22},"2027-03-01",{"name":47,"class":48},""]