[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Pop Test Oncology LLC\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100570850","phase-1-pt150-drug-for-use-in-alcohol-use-disorder-100570850",false,"NCT06712602","PT150 Drug for Use in Alcohol Use Disorder","Selective Glucocorticoid Receptor Antagonism in Alcohol Use Disorder: A Human Laboratory Study","Inclusion Criteria:\n\nMeet diagnostic criteria for AUD (moderate or severe) per the Diagnostic and Statistical Manual of Mental Disorders - 5th edition (DSM-5)\n\nNot seeking treatment at the time of the study\n\nEnglish-speaking\n\nBetween the ages of 21 and 55 years (individuals under 21 are excluded based on the recommendations of NIAAA that alcohol should not be administered to individuals under the legal drinking age)\n\nAbstinent from alcohol no more than 3 days per week on average\n\nPhysically and psychiatrically healthy other than the diagnoses for AUD or tobacco use disorder\n\nECG, read by cardiologist, within normal limits\n\nBody mass index of 19 - 35\n\nUsing an effective form of birth control (e.g., birth control pills, surgical sterilization, condoms, IUD, cervical cap with a spermicide or abstinence) if female\n\nAble to abstain from ALC for 12 hours prior to sessions\n\nNo contraindications to ALC or PT150\n\nExclusion Criteria:\n\nMeet diagnostic criteria for SUDs, save nicotine, other than AUD that in the opinion of a study physician would require medical intervention (e.g., opioid use disorder) or compromise the well-being of the participant\n\nHave abnormal blood chemistry, complete blood count or urinalysis values deemed clinically significant\n\nHave a history of serious physical disease or current physical disease (e.g., impaired cardiovascular functioning, histories of seizure, head trauma or CNS tumors)\n\nHave a current or past history of psychiatric disorder that would interfere with participation (e.g., psychotic \\[schizophrenia, schizoaffective\\]), bipolar, major depressive disorder)\n\nHave had suicidal ideations in the past 90 days\n\nPregnant or nursing\n\nAre unwilling\u002Funable to comply with study procedures\n\nParticipants scoring \\>6 on the Clinical Institute Withdrawal Assessment for Alcohol Revised (CIWA-Ar); the CIWA-Ar will be administered prior to each experimental session participants who score \\>6 will be excluded further participation.","ALL","21 Years","55 Years",{"count":20,"type":21},34,"ESTIMATED","INTERVENTIONAL",[24],"PHASE1","The goal of this study is to learn if PT150 can reduce the behavioral and physical effects of stress, alcohol, and alcohol use in people with alcohol use disorder.",[27],"Alcohol Use Disorder",[29,27,30],"Alcohol","Alcoholism","RECRUITING","2026-09-14",{"date":34,"type":35},"2026-09-16","ACTUAL",{"date":37,"type":35},"2025-02-01",{"date":39,"type":21},"2028-07-31",{"name":41,"class":42},"Pop Test Oncology LLC","INDUSTRY",""]