[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Prairie View A&M University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":53},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100658335","precision-nutrition-for-obesity-and-prediabetes-prevention-in-under-supported-communities-100658335",false,"NCT07850531","Precision Nutrition for Obesity and Prediabetes Prevention in Under-supported Communities","Building Capacity in Precision Nutrition to Address Obesity and Diabetes in Underserved Communities","PNOD","Inclusion Criteria:\n\n* Adults aged 18 to 65 years\n* African American or Hispanic\u002FLatino adults\n* Residents of Texas\n* Body mass index (BMI) ≥ 25 kg\u002Fm² and\u002For fasting blood glucose levels of 100-125 mg\u002FdL\n* Hemoglobin A1C (HbA1C) between 5.7% and 6.4%\n* Daily access to a cell phone and the internet\n* Able to participate in moderate-to-vigorous physical activity\n* Able and willing to provide informed consent\n\nExclusion Criteria:\n\n* Do not meet the inclusion criteria\n* Following a prescribed diet for any reason, including weight loss, within the previous 3 months\n* Diagnosed diabetes mellitus\n* Cardiovascular disease\n* Eating disorders\n* Lung disease\n* Liver disease\n* Thyroid disease\n* Crohn's disease\n* Pregnant\n* Lactating","ALL","18 Years","65 Years",{"count":21,"type":22},100,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized controlled trial will evaluate the effectiveness of a culturally sensitive precision nutrition intervention for improving obesity- and diabetes-related outcomes among African American and Hispanic\u002FLatino adults who are overweight, obese, or have prediabetes. Participants will be randomized to either a precision nutrition intervention group or a control group receiving standard nutrition counseling and educational materials. The intervention incorporates individualized dietary recommendations based on participant characteristics, including dietary habits, physical activity, socioeconomic factors, psychosocial factors, phenotype, and genotype. Outcomes will be assessed at baseline, 6 weeks, and 12 weeks and will include body weight, diet quality, fasting blood glucose, hemoglobin A1C, body composition, physical activity, blood pressure, and metabolic biomarkers. Feasibility, acceptability, and sustainability of the intervention will also be evaluated.",[28,29],"Obesity & Overweight","Prediabetes",[31,32,33,34,35,36,37,38,39,29,40],"Precision Nutrition","Personalized Nutrition","Weight Loss","Diabetes Prevention","Nutrition Counseling","Physical Activity","Culturally Sensitive Intervention","African American Adults","Hispanic\u002FLatino Adults","Obesity","NOT_YET_RECRUITING","2026-09-24",{"date":44,"type":45},"2026-09-30","ACTUAL",{"date":47,"type":22},"2026-10-01",{"date":49,"type":22},"2027-08-31",{"name":51,"class":52},"Prairie View A&M University","OTHER",""]