[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Prima Mente\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100657638","evaluation-of-blood-based-biomarkers-and-remote-cognitive-assessment-for-dementia-triage-sandbox-100657638",false,"NCT07842029","Evaluation of Blood-Based Biomarkers and Remote Cognitive Assessment for Dementia Triage (SANDBOX)","SANDBOX: Scalable Assessment of Neurodegenerative Diagnosis Via Biomarkers and Online Examination","SANDBOX","Inclusion Criteria:\n\n* The participant is willing and able to provide informed consent for participation in the study, or if unable to consent, a consultee (nearest of kin or holder of Power of Attorney) is available to make a declaration.\n* Eligibility for recruitment in Scotland is restricted to participants who are able to provide informed consent themselves; participants requiring consultee consent will not be recruited in Scotland.\n* Male or female, aged 50 years or older.\n* The participant is currently on a waiting list for a participating Memory Clinic.\n* The participant lives within traveling distance to a study site.\n* The participant agrees to complete all study procedures, including genetic testing.\n\nExclusion Criteria:\n\n* The participant may not enter the study if any of the following criteria apply:\n* The participant has known or anticipated challenges with venous blood sampling.\n* The participant is not fluent in English.\n* The participant has a historical diagnosis of dementia.","ALL","50 Years",{"count":20,"type":21},1000,"ESTIMATED","OBSERVATIONAL","Dementia is a leading cause of death in the UK, and long waits for diagnosis can delay access to care and treatment. The SANDBOX study is a research study in NHS Memory Clinics investigating whether providing clinicians with additional test results could help them diagnose dementia earlier.\n\nAdults aged 50 or over who have been referred to a Memory Clinic by their GP may be invited to take part. Taking part is voluntary and will not affect a participant's care. Participation adds to their NHS care and does not replace or delay it.\n\nParticipants complete three assessments: a blood test that measures two proteins which can indicate whether Alzheimer's-related changes may be happening in the brain (not currently available on the NHS); a genetic test for the APOE gene, which influences Alzheimer's risk; and a cognitive assessment of memory and thinking that includes a recorded speech task analysed for subtle language changes. All results are shared with the participant's clinician.\n\nThis research will help determine whether this approach can support earlier dementia diagnosis and improve care for patients across the UK.",[25,26],"Dementia","Cognitive Impairment",[15,28,29,30,31,32],"dementia","cognitive impairment","cognitive decline","Alzheimer's","Neurodegeneration","RECRUITING","2026-09-21",{"date":36,"type":37},"2026-09-25","ACTUAL",{"date":39,"type":37},"2025-11-13",{"date":41,"type":21},"2027-11-30",{"name":43,"class":44},"Prima Mente","INDUSTRY",12,""]