[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Shanghai University of Sport\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":149},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,44,74,103,121],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100652246","hippocampal-temporal-interference-stimulation-for-memory-and-dual-task-postural-control-in-older-adults-with-mild-cognitive-impairment-100652246",false,"NCT07771036","Hippocampal Temporal Interference Stimulation for Memory and Dual-Task Postural Control in Older Adults With Mild Cognitive Impairment","Effects and Underlying Mechanisms of Hippocampal-Targeted Temporal Interference Stimulation on Memory Function and Dual-Task Postural Control in Older Adults With Mild Cognitive Impairment","1. Aged 65 years or older;\n2. Presence of subjective memory complaints;\n3. Objective cognitive impairment: screened using the Montreal Cognitive Assessment-Bejingversion (MoCA-BJ). The MoCA-BJ total score is 30 points. For individuals with \\\u003C12 years ofeducation, 1 point is added to the raw total score (corrected total score capped at 30 points); acorrected total score \\\u003C26 points indicates risk of cognitive impairment;\n4. Clinical Dementia Rating (CDR) score of 0.5;\n5. Does not meet diagnostic criteria for dementia: Mini-Mental State Examination (MMSE) scores\\>18 for illiterate individuals, 221 for those with primary school education, and \\>25 for those withjunior high school education or above;6. Retains independent activities of daily living (ADL) and is capable of cooperating with allassessments and interventions.","ALL","65 Years",{"count":19,"type":20},21,"ESTIMATED","INTERVENTIONAL",[23],"NA","This trial aims to investigate whether a single session of 40 Hz hippocampal temporal interference stimulation can improve memory function and dual-task postural control among older adults with mild cognitive impairment (MCI). The primary research questions to be addressed are as follows:\n\n* Can 40 Hz hippocampal temporal interference stimulation boost memory test performance in older adults with MCI?\n* Can 40 Hz hippocampal temporal interference stimulation improve walking and balance ability under dual-task conditions in older adults with MCI? Researchers will compare active 40 Hz hippocampal temporal interference stimulation against sham stimulation to identify whether this intervention yields positive immediate effects on memory function and dual-task postural control.\n\nParticipants will be required to:\n\n* Attend three laboratory visits over approximately three weeks, and receive one session of active stimulation and one session of sham stimulation in random order, with an interval of at least seven days between the two stimulation visits;\n* Complete memory and motor function assessments before and after each stimulation session;\n* Undergo functional magnetic resonance imaging (fMRI) scans to detect changes in brain activity.",[26],"Mild Cognitive Impairment (MCI)",[28,29,30],"Mild Cognitive Impairment","Temporal Interference Stimulation","TIs","RECRUITING","2026-08-13",{"date":34,"type":35},"2026-08-18","ACTUAL",{"date":37,"type":35},"2026-07-30",{"date":39,"type":20},"2027-07-30",{"name":41,"class":42},"Shanghai University of Sport","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100632792","remotely-supervised-home-based-transcranial-temporal-interference-stimulation-on-motor-symptoms-in-parkinsons-disease-100632792","NCT07518290","Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease","Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease: Protocol For a Double Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of Parkinson's disease according to established clinical criteria\n* Mild-to-moderate disease severity, defined as Hoehn and Yahr stage 1.5-3;\n* Age between 40 and 80 years;\n* Stable anti-parkinsonian medication regimen;\n* Ability to walk unaided for at least 2 minutes.\n\nExclusion Criteria:\n\n* contraindications to TIs (e.g., metal implantation, pacemakers, etc.);\n* the use of DBS;\n* significant cognitive impairment as defined by the diagnosis of Alzheimer's disease or dementia, or Montreal Cognitive Assessment (MoCA) total score\\\u003C21, a recommended threshold for dementia in PD;\n* diagnosis of other neurological conditions such as multiple sclerosis, previous stroke;\n* report of severe lower-extremity arthritis, pain, or orthopedic problems significantly affecting gait;\n* physician-diagnosis of schizophrenia or other psychiatric illness;\n* an unwillingness to cooperate or participate in the study protocol. Eligible and interested participants will then be enrolled and complete baseline assessments before the randomization.","40 Years","80 Years",{"count":54,"type":20},68,[23],"The goal of this clinical trial is to learn if home-based temporal interference stimulation (TIS) works to improve motor symptoms in people with Parkinson's disease (PD). It will also learn about the safety of this treatment. The main questions it aims to answer are:\n\n1. Does home-based TIS improve movement problems such as slow movement, stiffness, and walking difficulty?\n2. Are the effects maintained after the treatment ends?\n3. What medical problems (adverse events) occur during treatment? Researchers will compare active TIS to a sham treatment (a look-alike procedure that does not deliver active stimulation) to see if TIS works.\n\nParticipants will:\n\n1. Receive active TIS or sham stimulation once a day for 4 weeks at home under remote supervision\n2. Visit the clinic at specific time points for movement assessments\n3. Complete online questionnaires about symptoms and quality of life",[58,59],"PARKINSON DISEASE (Disorder)","Motor Symptoms",[61,62,63,64,65],"Parkinson disease","Transcranial temporal interference stimulation","Home-based intervention","Motor symptom","Randomized controlled trial","2026-08-11",{"date":32,"type":35},{"date":69,"type":35},"2026-04-04",{"date":71,"type":20},"2028-03-30",{"name":41,"class":42},2,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":81,"sex":16,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":21,"phases":86,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":43},"100650672","effects-of-blood-flow-restriction-training-on-neuromuscular-function-and-performance-in-artistic-jump-rope-athletes-100650672","NCT07750977","Effects of Blood Flow Restriction Training on Neuromuscular Function and Performance in Artistic Jump Rope Athletes","Effects of Blood Flow Restriction Training on Upper and Lower Limb Neuromuscular Function, Body Composition, Physiological Responses, and Sport Performance in Artistic Jump Rope Athletes: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Adults aged 18 to 25 years.\n2. Current artistic jump rope athletes with at least 2 years of regular artistic jump rope training experience.\n3. Participants who are able to perform artistic jump rope skills and complete all study-related assessments and training procedures.\n4. Participants who are physically healthy and have no medical conditions that may interfere with exercise testing or blood flow restriction training.\n5. Participants who have no acute or chronic musculoskeletal injuries affecting the upper limbs, lower limbs, or trunk.\n6. Participants who voluntarily agree to participate and provide written informed consent before enrollment.\n\nExclusion Criteria:\n\n1. Participants younger than 18 years or older than 25 years.\n2. Presence of cardiovascular disease, peripheral vascular disease, respiratory disease, neurological disease, metabolic disease, coagulation disorders, history of thrombosis, severe varicose veins, severe hypertension, or other conditions that may affect exercise safety.\n3. Presence of acute or chronic musculoskeletal injuries, including injuries involving muscles, joints, ligaments, tendons, or bones, that prevent safe completion of study procedures.\n4. Significant pain, severe fatigue, insufficient recovery, poor sleep condition, or other health conditions that may affect exercise performance or participant safety.\n5. Use of medications, nutritional supplements, or sports supplements within the previous week that may influence cardiovascular function, muscle metabolism, blood lactate response, heart rate variability, neuromuscular activation, fatigue response, or exercise performance.\n6. Skin damage, infection, dermatological disorders, severe allergy history, or other conditions affecting blood flow restriction cuff application or surface electromyography electrode placement.\n7. Inability to understand the study procedures or inability to complete required assessments, including physical performance tests, blood flow restriction training, or blood lactate testing.\n8. Refusal to participate in blood flow restriction training or withdrawal of informed consent during the study.\n\nExclusion Criteria:\n\n* 1\\. Age younger than 18 years or older than 25 years. 2. Presence of cardiovascular disease, peripheral vascular disease, respiratory disease, neurological disease, metabolic disease, coagulation abnormalities, history of thrombosis, severe varicose veins, severe hypertension, or other conditions that may affect exercise testing or blood flow restriction training safety.\n\n  3\\. Current acute or chronic injuries involving muscles, joints, ligaments, tendons, or bones that prevent safe completion of study procedures.\n\n  4\\. Severe fatigue, poor recovery status, significant pain, insufficient sleep, or other conditions that may influence exercise performance or participant safety.\n\n  5\\. Use of medications, nutritional supplements, or sports supplements that may affect cardiovascular function, muscle metabolism, blood lactate response, heart rate variability, neuromuscular activation, fatigue response, or exercise performance within the previous week.\n\n  6\\. Skin damage, infection, dermatological disorders, severe allergy history, or other conditions affecting blood flow restriction cuff application or surface electromyography electrode placement.\n\n  7\\. Inability or unwillingness to complete study assessments, blood flow restriction training, blood lactate testing, or other required procedures.\n\n  8\\. Withdrawal of consent or inability to comply with the study protocol during the intervention period.",true,"18 Years","25 Years",{"count":85,"type":20},30,[23],"The goal of this randomized controlled trial is to investigate whether blood flow restriction training can improve physical function and sports performance in artistic jump rope athletes. The study will include 30 healthy artistic jump rope athletes aged 18 to 25 years. The main questions this study aims to answer are:\n\n1. Does blood flow restriction training improve neuromuscular function compared with conventional training?\n2. Does blood flow restriction training improve muscle strength, power, body composition, physiological responses, and artistic jump rope performance?\n\nResearchers will compare participants receiving blood flow restriction training with participants performing conventional training to determine whether blood flow restriction training provides additional benefits. Participants will complete an 8-week training program and undergo assessments before and after the intervention, including muscle function tests, physical performance tests, body composition measurements, and physiological response evaluations.",[89,90],"Neuromuscular Function","Athletic Performance Enhancement",[92,93,89],"Blood Flow Restriction Training","Artistic Jump Rope","NOT_YET_RECRUITING","2026-08-03",{"date":97,"type":35},"2026-08-06",{"date":99,"type":20},"2026-08-30",{"date":101,"type":20},"2026-12-15",{"name":41,"class":42},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":81,"sex":16,"minAge":82,"maxAge":83,"enrollmentInfo":110,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":4},"100649545","effects-of-blood-flow-restriction-training-on-physical-function-muscle-adaptations-and-performance-in-roller-skaters-100649545","NCT07736157","Effects of Blood Flow Restriction Training on Physical Function, Muscle Adaptations, and Performance in Roller Skaters","Effects of Blood Flow Restriction Training on Neuromuscular Function, Jump Performance, and Dynamic Balance Under Non-Fatigued and Fatigued Conditions, and on Muscle Morphology, Body Composition, Strength, Physiological Responses, Anaerobic Performance, and Roller Skating-Specific Performance in Competitive Roller Skaters","Inclusion Criteria:\n\n1. Aged 18 to 25 years.\n2. Currently active or trained competitive roller skaters with regular roller skating-specific training experience who meet at least one of the following criteria:\n\n   1. Hold a Chinese National Athlete Grade II classification or higher; or\n   2. Have completed at least 2 years of continuous roller skating-specific training, maintained systematic training during the previous year, and participated in provincial-level competitions.\n3. In good general health, without known cardiovascular, peripheral vascular, respiratory, neurological, metabolic, or coagulation disorders, a history of thrombosis, severe varicose veins, severe hypertension, or other conditions that may affect the safety of blood flow restriction training or high-intensity exercise testing.\n4. No acute or unresolved chronic injury involving the joints, muscles, ligaments, tendons, or bones of the lower limbs, and no clinically significant lower-limb pain that would interfere with roller skating, jumping, or balance testing.\n5. Able to safely complete roller skating-specific testing, jump and balance testing, cycle ergometer-based fatigue induction, and standardized roller skating-specific fatigue induction.\n6. Intact and healthy skin on the thighs, without wounds, infection, skin disease, severe allergy, or other conditions that may interfere with blood flow restriction cuff placement or surface electromyography electrode application.\n7. Stable sleep, training, and recovery status during the week before testing, without evidence of marked fatigue, inadequate recovery, persistent muscle soreness, substantial performance decline, severe sleep insufficiency, or serious psychological distress.\n8. A pain score of 0 to 3 on the Numeric Rating Scale and a pretest rating of perceived exertion of 12 or lower.\n9. No use during the previous week of medications, nutritional supplements, or sports supplements that may affect cardiovascular function, muscle metabolism, blood lactate, heart rate variability, neuromuscular activation, fatigue responses, or exercise performance.\n10. Familiar with the roller skating-specific testing procedures and able to follow all testing and training instructions.\n11. Willing to undergo blood flow restriction training and all required assessments.\n12. Able to understand the study procedures, provide written informed consent, and voluntarily participate.\n\nExclusion Criteria:\n\n1. Age outside the range of 18 to 25 years or failure to meet the required roller skating training, athlete classification, systematic training, or competition-experience criteria.\n2. Cardiovascular disease, peripheral vascular disease, respiratory disease, neurological disease, metabolic disease, coagulation disorder, history of thrombosis, severe varicose veins, severe hypertension, circulatory impairment, or another contraindication to blood flow restriction training or high-intensity exercise testing.\n3. Acute lower-limb musculoskeletal injury or an unresolved chronic injury that prevents safe completion of the testing or fatigue-induction procedures.\n4. Clinically significant lower-limb pain, severe sleep insufficiency, inadequate recovery, suspected overtraining, serious psychological distress, or another condition that may compromise participant safety or data validity.\n5. Use during the previous week of medications, nutritional supplements, or sports supplements that may affect the study outcomes.\n6. Skin wounds, infection, skin disease, severe allergy, or another condition affecting blood flow restriction cuff placement or surface electromyography electrode application.\n7. Inability to understand or comply with the study procedures or to safely complete the required surface electromyography, force-platform, Y-Balance, jump, and fatigue-induction assessments.\n8. Refusal to undergo blood flow restriction training or any required study procedure.\n9. Failure to provide written informed consent.",{"count":85,"type":20},[23],"This randomized controlled trial evaluates the effects of adding blood flow restriction training to regular roller skating training on neuromuscular function under non-fatigued and fatigued conditions, muscle morphology, body composition, physiological responses, lower-limb strength, and roller skating performance in competitive roller skaters.\n\nThirty participants aged 18 to 25 years will be randomly assigned to either a blood flow restriction training group or a regular training control group. Both groups will complete the same standardized 10-week roller skating training program. The blood flow restriction training group will wear pressure cuffs individualized according to each participant's arterial occlusion pressure during selected training sessions three times per week, while the control group will complete the same training without blood flow restriction.\n\nBefore and after the intervention, participants will complete standardized assessments of muscle morphology using musculoskeletal ultrasound, body composition using dual-energy X-ray absorptiometry, and lower-limb strength using handheld dynamometry and one-repetition maximum tests. Physiological responses will be evaluated using blood lactate concentration and heart rate variability. Roller skating performance will be assessed using sprint, repeated-sprint, and endurance skating tests.\n\nNeuromuscular function, jump performance, and balance will also be assessed under both non-fatigued and fatigued conditions. Surface electromyography and force-platform data will be collected simultaneously during selected jump and single-leg balance tasks. The Y-Balance Test will be conducted separately without surface electromyography.\n\nThe study aims to determine whether blood flow restriction training improves muscle and neuromuscular adaptations, body composition, strength, physiological responses, and roller skating performance, and whether it helps roller skaters maintain neuromuscular function, jump performance, and balance during fatigue.",[90],"2026-07-25",{"date":37,"type":35},{"date":117,"type":20},"2026-08-20",{"date":119,"type":20},"2026-11-30",{"name":41,"class":42},{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":127,"eligibilityCriteria":128,"healthyVolunteers":81,"sex":16,"minAge":129,"maxAge":83,"enrollmentInfo":130,"targetDuration":4,"studyType":21,"phases":132,"briefSummary":133,"conditions":134,"keywords":137,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":146,"leadSponsor":148,"locationsCount":43},"100634311","effects-of-low-intensity-blood-flow-restriction-training-on-strength-and-kicking-performance-in-taekwondo-athletes-100634311","NCT07538037","Effects of Low-Intensity Blood Flow Restriction Training on Strength and Kicking Performance in Taekwondo Athletes","Effects of Low-Intensity Blood Flow Restriction Training on Lower-Limb Strength and Kicking Performance in Taekwondo Athletes: A Randomized Controlled Trial","BFRT","Inclusion Criteria:\n\n\\- Taekwondo athletes aged 16-25 years National-level athletes (National Level 1 or higher); Minimum of 3 years of systematic taekwondo training experience; Free from lower-limb injury within the past 6 months; Able to complete the training intervention and testing procedures.\n\nExclusion Criteria:\n\n\\- History of cardiovascular, metabolic, or neurological disorders; Current musculoskeletal injury or pain affecting training; Participation in other structured resistance training programs during the study period; Use of medications or supplements that may affect physical performance Inability or unwillingness to provide informed consent.","16 Years",{"count":131,"type":20},18,[23],"This study aims to investigate the effects of low-intensity blood flow restriction training (LI-BFRT) on lower-limb strength and kicking performance in taekwondo athletes. Blood flow restriction training is a method that partially restricts blood flow to the muscles during exercise, which may improve performance while reducing training load.",[135,136],"Physical Performance","Athletic Performance",[92,138,139,136,140,141],"Low-Intensity Resistance Training","Taekwondo Athletes","Explosive Strength","Anaerobic Power","2026-04-10",{"date":144,"type":35},"2026-04-20",{"date":142,"type":20},{"date":147,"type":20},"2026-06-29",{"name":41,"class":42},""]