[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Shifa Tameer-e-Millat University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":249},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,53,80,108,131,169,192,222],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100652741","comparative-effects-of-integrated-versus-sequential-approaches-to-dual-task-training-in-elderly-with-mild-to-moderate-cognitive-impairment-a-four-arm-randomized-controlled-trial-100652741",false,"NCT07775079","Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment","Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment: A Four-Arm Randomized Controlled Trial","nill","Inclusion Criteria:\n\n* Age \\> 55 years\n* MoCA: 10-25\n* MMSE: 10-23\n* Diagnosed cognitive impairment\n* Able to participate in training\n\nExclusion Criteria:\n\n* Severe cognitive impairment\n* Severe physical sensory limitations\n* Unstable medical conditions\n* Participation in other trials",true,"ALL","55 Months","85 Months",{"count":22,"type":23},96,"ESTIMATED","INTERVENTIONAL",[26],"NA","Mild and Moderate cognitive impairment is a condition characterized by a noticeable decline in cognitive abilities, including memory and thinking skills, which is greater than expected for an individual's age but does not significantly interfere with daily life. Early intervention is essential to prevent further cognitive decline and progression to dementia.\n\nDual-task training has emerged as an effective rehabilitation approach that combines cognitive and motor tasks to enhance neuroplasticity and improve both physical and cognitive performance. This study is designed to investigate the effectiveness of dual-task training compared to conventional therapy in individuals with mild cognitive impairment.\n\nParticipants meeting the inclusion criteria will be recruited and randomly allocated into intervention and control groups. The intervention group will receive structured dual-task training, which may include activities such as walking while performing cognitive tasks (e.g., counting, word recall), balance exercises combined with mental tasks, and functional activities requiring divided attention. The control group will receive standard rehabilitation or single-task training.\n\nThe intervention will be conducted over a specified duration (e.g., several weeks), with sessions held multiple times per week. Outcome measures will be assessed at baseline and after completion of the intervention. The primary outcome will be cognitive function measured using the Mini-Mental State Examination (MMSE). Secondary outcomes may include balance, mobility, and functional performance.\n\nData will be analyzed to determine the effectiveness of dual-task training in improving cognitive and functional outcomes. The results of this study may contribute to evidence-based rehabilitation practices and support the use of dual-task interventions in clinical settings.",[29,30],"Mild Cognitive Impairment (MCI)","Moderate Cognitive Impairment",[32,33,34,35,36,37,38,39],"Dual-task training","Cognitive Function","Rehabilitation","MMSE","MoCA","Balance training","Integrated training","Sequential training","RECRUITING","2026-08-19",{"date":43,"type":44},"2026-08-21","ACTUAL",{"date":46,"type":44},"2026-06-25",{"date":48,"type":23},"2026-08-30",{"name":50,"class":51},"Shifa Tameer-e-Millat University","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":18,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":24,"phases":63,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":78,"leadSponsor":79,"locationsCount":52},"100651633","comparative-evaluation-of-immediate-vs-progressive-standing-dual-task-training-in-elderly-with-mild-and-moderate-cognitive-impairment-100651633","NCT07764250","Comparative Evaluation of Immediate vs Progressive Standing Dual Task Training in Elderly With Mild and Moderate Cognitive Impairment","Immediate Versus Progressive-Standing Dual-Task Training: A Comparative Evaluation in Elderly With Mild and Moderate Cognitive Impairment","Inclusion Criteria:\n\nAge ≥55 years Mild or moderate cognitive impairment MoCA 10-25 MMSE 10-23 Able to participate Provides informed consent\n\nExclusion Criteria:\n\nSevere cognitive impairment Severe sensory or musculoskeletal impairments Unstable medical conditions Participation in another intervention study","55 Years","90 Years",{"count":22,"type":23},[26],"older adults with mild and moderate cognitive impairment. compare immediate vs progressive standing dual-task training. assess balance, cognition, executive function, mobility, and quality of life.",[66,67,30],"Cognitive Impairment","Cognitive Impairment, Mild",[69,70,71,72,73],"CI","MCI","DTT","ISDTT","PSDDT","2026-08-09",{"date":76,"type":44},"2026-08-13",{"date":46,"type":44},{"date":48,"type":23},{"name":50,"class":51},{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":18,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":24,"phases":91,"briefSummary":92,"conditions":93,"keywords":95,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":52},"100649492","effects-of-core-stabilization-exercises-on-postural-control-in-spastic-diplegic-cp-children-100649492","NCT07736417","Effects of Core Stabilization Exercises on Postural Control in Spastic Diplegic CP Children","Effects of Core Stabilization Exercises on Postural Control in Spastic Diplegic CP Children: a Randomized Control Trial","Inclusion Criteria:\n\n* Children diagnosed with spastic diplegic cerebral palsy\n* Gross Motor Function Classification System (GMFCS) Levels II-III\n* Stable medical management for at least 3 months prior to enrollment\n* Ability to understand and follow simple verbal instructions\n\nExclusion Criteria:\n\n* Fixed contracture or musculoskeletal deformities limiting exercise\n* Orthopedic surgery or botulinum injection within the previous 3 months\n* Uncontrolled epilepsy\n* Severe visual impairment\n* Participation in another rehabilitation intervention during the study period","4 Years","12 Years",{"count":90,"type":23},60,[26],"This randomized controlled trial will evaluate the effectiveness of a 12-week comprehensive core stabilization exercise program on balance, trunk control, and gross motor function in children with spastic diplegic cerebral palsy. Outcome measures will be assessed at baseline and at the end of the intervention to determine changes following treatment.",[94],"Spastic Diplegic Cerebral Palsy",[96,97,98],"Balance","Trunk control","Gross motor function","NOT_YET_RECRUITING","2026-07-29",{"date":102,"type":44},"2026-07-31",{"date":104,"type":23},"2026-08",{"date":106,"type":23},"2026-11",{"name":50,"class":51},{"id":109,"slug":110,"hasResults":11,"nctId":111,"briefTitle":112,"officialTitle":113,"acronym":4,"eligibilityCriteria":114,"healthyVolunteers":11,"sex":18,"minAge":115,"maxAge":116,"enrollmentInfo":117,"targetDuration":4,"studyType":24,"phases":119,"briefSummary":120,"conditions":121,"keywords":4,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":4},"100649553","systemic-couple-therapy-for-marital-dynamics-and-mental-health-100649553","NCT07736508","Systemic Couple Therapy for Marital Dynamics and Mental Health","Systemic Couple Therapy for Enhancement of Marital Dynamics and Mental Health Among Individuals With Depression: A Mixed Method Approach","Inclusion Criteria:\n\n* Inclusion criteria\n\n  * Participant must be 18 years or older to participate in the study.\n  * At least one partner must meet the diagnostic criteria for depression (mild to moderate) as defined by the DSM-5 TR.\n  * Participants must be married for at least a year to ensure adequate context for systemic couple therapy.\n  * Both partners must agree to participate in the study, showing their willingness to engage in the intervention and complete all required assessments.\n\nExclusion Criteria:\n\n* • Participants with severe depression, psychosis, bipolar disorder, or active substance use disorder will be excluded from the study due to potential interference with therapy.\n\n  * Participants currently engaged in ongoing individual psychotherapy during the study period will be excluded to avoid confounding treatment effects.\n  * Additionally, couples will be excluded if there is presence of domestic violence or abuse, as identified during the initial screening or clinical interview, to ensure participant safety.\n  * Couple who will be undergoing legal separation or divorce proceedings will not be eligible to participate, as the focus of the systemic couple therapy is relational commitment and stability.","18 Years","60 Years",{"count":118,"type":23},48,[26],"The goal of this clinical trial (randomized controlled trial within a mixed-method study) is to learn whether Systemic Couple Therapy (SCT) can treat depression and improve relational functioning in married couples where at least one partner is experiencing mild to moderate depression and relational distress.\n\nThe main questions it aims to answer are:\n\n* Does Systemic Couple Therapy improve relationship quality, marital communication, dyadic coping, interpersonal functioning, and overall mental health?\n* Does Systemic Couple Therapy reduce depressive symptoms compared to Treatment-as-Usual (TAU)? Researchers will compare Systemic Couple Therapy (intervention group) with Treatment-as-Usual (control group) to see if SCT leads to greater improvements in mental health and relational outcomes and greater reduction in depression.\n\nParticipants will:\n\n* Complete standardized psychological assessments at baseline, post-treatment (8 weeks), and 3-month follow-up\n* Participate in 8 weekly Systemic Couple Therapy sessions (intervention group)\n* Receive Treatment-as-Usual such as routine couple therapy services or medication (control group)",[122],"Depression","2026-07-25",{"date":125,"type":44},"2026-07-30",{"date":127,"type":23},"2026-08-01",{"date":129,"type":23},"2026-12-31",{"name":50,"class":51},{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":137,"eligibilityCriteria":138,"healthyVolunteers":11,"sex":18,"minAge":139,"maxAge":140,"enrollmentInfo":141,"targetDuration":4,"studyType":24,"phases":143,"briefSummary":144,"conditions":145,"keywords":157,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":4},"100646492","effect-of-a-structured-educational-intervention-through-mobile-app-on-hemoglobin-a1c-hba1c-self-efficacy-and-self--care-in-adolescent-with-type-1-diabetes-t1dm-100646492","NCT07689318","Effect of a Structured Educational Intervention Through Mobile App on Hemoglobin A1c (HbA1c), Self-Efficacy and Self- Care in Adolescent With Type 1 Diabetes (T1DM)","Effect of a Structured Educational Intervention Through Mobile App on Hemoglobin A1c (HbA1c), Self-Efficacy and Self- Care in Adolescent With Type 1 Diabetes A Pilot RCT","(T1DM)","Inclusion Criteria:\n\nAdolescents aged 10 to 19 years. Diagnosed with Type 1 Diabetes Mellitus (T1DM) by a physician for at least 6 months.\n\nHbA1c greater than or equal to 7%. Have access to a smartphone or tablet (owned by the participant or parent\u002Fguardian).\n\nExclusion Criteria:\n\nUse of an insulin pump. Current use of any smartphone application for diabetes self-management. Presence of comorbid conditions that may interfere with participation in the study.\n\nDiagnosis of intellectual disability or other cognitive impairment documented in the medical record that may limit the participant's ability to complete questionnaires or comply with intervention requirements.","10 Years","19 Years",{"count":142,"type":23},84,[26],"This study aims to evaluate the effectiveness of a mobile health (mHealth) educational intervention for adolescents with Type 1 Diabetes Mellitus (T1DM). Adolescents often face challenges in maintaining optimal blood glucose control and performing regular self-care. In this study, participants will receive structured diabetes education through a mobile application designed to improve their knowledge, self-efficacy (SE), and self-management skills. The impact of the intervention will be assessed by measuring changes in HbA1c levels, diabetes self-efficacy, and self-care (SC)behaviors over time. These findings may help determine whether mobile app-based education can support better diabetes management among adolescents.",[146,147,148,149,150,151,152,153,154,155,156],"Type 1 Diabetes (Juvenile Onset)","Type 1 Diabetes","Type 1 Diabetes Mellitus","HbA1c","HbA1c Level","Self Care","Self Efficacy","Mobile Application","MOBILE WEB-BASED INTERVENTION PROGRAM","Mobile Apps","Nurse Led Intervention",[158,159,160],"type 1 diabetes Mellitus, educational intervention , mobile app, HbA1c","Self Efficacy , Self Care","adolescents","2026-07-07",{"date":163,"type":44},"2026-07-08",{"date":165,"type":23},"2026-07-01",{"date":167,"type":23},"2026-11-30",{"name":50,"class":51},{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":173,"acronym":174,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":18,"minAge":4,"maxAge":60,"enrollmentInfo":176,"targetDuration":4,"studyType":24,"phases":178,"briefSummary":179,"conditions":180,"keywords":182,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":191,"locationsCount":52},"100644017","effectiveness-of-attention-focus-training-on-attention-and-quality-of-life-in-stroke-100644017","NCT07668245","Effectiveness of Attention Focus Training on Attention and Quality of Life in Stroke","AQoLStroke","Inclusion Criteria:\n\n* Participants diagnosed with stroke\n* Able to ambulate at least with assistance\n* Medically stable\n\nExclusion Criteria:\n\n* Severe cognitive impairment (MMSE \\\u003C 24)\n* Pre-existing dementia\n* Visual\u002Fhearing impairment",{"count":177,"type":23},46,[26],"This RCT will determine the effects of attention focus training which is a comprehensive intervention to improve cognitive outcomes. Attention is one of the major cognitive outcome and problems with attention can deteriorate the quality of life of people suffering from stroke. Intervention will be provided for 4 weeks. Outcomes will be assessed at baseline and after provision of intervention.",[181],"Stroke",[183,184,181],"Attention","Quality of life",{"date":186,"type":44},"2026-06-30",{"date":188,"type":23},"2026-07-03",{"date":190,"type":23},"2026-10-03",{"name":50,"class":51},{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":4,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":18,"minAge":199,"maxAge":4,"enrollmentInfo":200,"targetDuration":4,"studyType":24,"phases":202,"briefSummary":203,"conditions":204,"keywords":208,"overallStatus":99,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":52},"100588927","skill-building-education-of-arteriovenous-fistula-self-care-behaviors-and-quality-of-life-of-patients-on-hemodialysis-100588927","NCT06947772","Skill Building Education of Arteriovenous-Fistula Self-Care Behaviors and Quality of Life of Patients on Hemodialysis","Effectiveness of Skill Building Education on Arteriovenous Fistula Self-Care Behaviors and Quality of Life of Patients on Hemodialysis","Inclusion Criteria:\n\n* Inclusion Criteria\n\nThe study will include patients:\n\n1. diagnosed with end-stage renal disease on hemodialysis through an arteriovenous fistula\n2. aged 18 years or above.\n3. who can read and understand the Urdu language.\n\nExclusion Criteria:\n\nExclusion Criteria\n\nThe study will exclude patients:\n\n1. having any physical or mental disabilities that can interfere with their capacity to perform daily life activities.\n2. with any visual and hearing impairment. -","18 Months",{"count":201,"type":23},274,[26],"The purpose of this study is to assess the effectiveness of skill building educational interventions in improving the self-care behaviors and quality of life of AVF in hemodialysis patients. This study will address questions.\n\nWhat is the effect of skill building education on the self-care behaviors of AVF care and quality of life in patients in patients undergoing hemodialysis treatment? A total 274 participants will be recruited from dialysis units of the study hospitals. Using random allocation 137 participants will be assigned to the control group and 137 to the intervention group. The intervention group will additionally receive a skill building education for improving their self-care behaviors and quality of life of AVF.\n\nResearcher will implement skill building educational intervention in interventional group to enhance the self-care behaviors and quality of life. This intervention have two session, first is theoretical and another one is practical. The primary outcome of this study is AVF self-care behaviors and secondary outcome is quality of life related to AVF. This outcome will be assessed using the Self-care Behaviors Scale with Arteriovenous Fistula in Hemodialysis patients (ASBHD-AVF). The secondary outcome will be assessed using the Hemodialysis Access-related Quality of Life (HARQ) which is a self-administered tool develop by Nordyke.\n\nThe primary and secondary outcomes will be assessed at: baseline, after the completion of the intervention, and follow-up data will be collected at the second and sixth weeks after intervention is completed. Data will be analyzed using the Statistical Package of Social Science (SPSS) version 25. Descriptive statistics, means and standard deviations will be used for the continuous variables, while frequencies and percentages will be utilized for categorical demographic data (gender, educational level, hemodialysis frequency, items of self-care behavior scale, QOL). Normality of data will be check and applied test accordingly.",[205,206,207],"Chronic Kidney Disease","Hemodialysis","Hemodialysis Access Failure",[209,210,211,212,213],"Slef-care behaviors","hemodialysis","quality of life","arteriovenous fistula","Kidney disease","2025-04-20",{"date":216,"type":44},"2025-04-27",{"date":218,"type":23},"2025-05-01",{"date":220,"type":23},"2025-08-30",{"name":50,"class":51},{"id":223,"slug":224,"hasResults":11,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":4,"eligibilityCriteria":228,"healthyVolunteers":11,"sex":18,"minAge":229,"maxAge":230,"enrollmentInfo":231,"targetDuration":4,"studyType":24,"phases":233,"briefSummary":234,"conditions":235,"keywords":237,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":240,"lastUpdatePostDateStruct":241,"startDateStruct":243,"completionDateStruct":245,"leadSponsor":247,"locationsCount":248},"100547996","effect-of-facilitated-tucking-and-gentle-human-touch-on-procedural-pain-among-neonates-100547996","NCT06415240","Effect of Facilitated Tucking and Gentle Human Touch on Procedural Pain Among Neonates","Assistant Clinical Nurse Manager Working in Neonatal Intensive Care Unit","Inclusion Criteria:\n\n1. Both term and preterm neonates.\n2. APGAR scores of a minimum of 6 at one minute and 8 at 5 minutes\n3. Admitted to the Neonatal Intensive Care Unit\n4. Undergoing arterial prick for the first time.\n\nExclusion Criteria:\n\n1. Documented birth asphyxia\n2. Congenital anomalies\n3. Neurological diagnosis,\n4. ventilated with paralysis\n5. Extremely premature newborns (Gestational age \\\u003C 28 weeks)","1 Day","28 Days",{"count":232,"type":23},159,[26],"This is a Randomized Control Trial intended to investigate the effect of two non-pharmacological interventions on procedural pain among neonates.",[236],"Non Pharmacological Pain Management",[236,238,239],"Neonates","Procedural Pain","2024-08-19",{"date":242,"type":44},"2024-08-20",{"date":244,"type":44},"2024-05-20",{"date":246,"type":23},"2024-11-30",{"name":50,"class":51},2,""]