[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Shu-Mei Wang\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":64},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100599557","effects-of-ras-in-sz-100599557",false,"NCT07086040","Effects of RAS in SZ","Effects of Rhythmic Auditory Stimulation Therapy on Upper-Limb Movements, Function, and Quality of Life in Patients With Schizophrenia: Randomized Controlled Trials","\\[For SZ patients\\]\n\nInclusion Criteria:\n\n* A diagnosis of schizophrenia or schizoaffective disorder\n* Between 18 to 60 years old\n* Keeping the same antipsychotics and the same dosage at least 4 weeks right before joining the study\n* A Edinburgh Handedness Inventory score of \\> 60\n* A Montreal Cognitive Assessment score of ≥ 24\n\nExclusion Criteria:\n\n* Substance abuse or drug abuse\n* Neurological diseases or medical conditions that affect upper-limb movements and hearing\n* Other psychiatric diagnoses in addition to a diagnosis of schizophrenia or schizoaffective disorder\n\n\\[For healthy participants\\]\n\nInclusion Criteria:\n\n* Between 18 to 60 years old\n* A Edinburgh Handedness Inventory score of \\> 60\n* A Montreal Cognitive Assessment score of ≥ 24\n\nExclusion Criteria:\n\n* Substance abuse or drug abuse\n* Neurological diseases or medical conditions that affect upper-limb movements and hearing\n* Psychiatric diagnoses\n* Taking psychotropic medications\n* Presence of first-degree relatives or siblings with diagnoses of psychiatric diseases.",true,"ALL","18 Years","60 Years",{"count":21,"type":22},140,"ESTIMATED","INTERVENTIONAL",[25],"NA","The two main groups of medicated patients with schizophrenia (SZ) are those receiving second-generation antipsychotics and those receiving first-generation antipsychotics. The purpose of this research project is to target each patient group to examine effects of rhythmic auditory stimulation (RAS) on upper-limb movements in medicated SZ patients in a 6-month follow-up period.\n\nThe main questions of this project are:\n\n1. Does RAS reduce severity of upper-limb bradykinesia (slow movements) and dyskinesia (repetitive and involuntary movements) after intervention, at 3-month follow-up and 6-month follow-up in SZ patients receiving second-generation antipsychotics? and\n2. Does RAS reduce severity of upper-limb bradykinesia and dyskinesia after intervention, at 3-month follow-up and 6-month follow-up in SZ patients receiving first-generation antipsychotics?\n\nResearchers will compare upper-limb movement training with the aid of RAS to upper-limb movement training without the aid of RAS to see if RAS works to improve upper-limb movements in SZ patients. Participants will:\n\n1. Undergo an interview and movement tests and fill out questionnaires before and after the movement training program and at 3-month follow-up and 6-month follow-up; and\n2. Receive movement training for 40 minutes per session for a total of 21 sessions.",[28],"Schizophrenia and Schizoaffective Disorder","NOT_YET_RECRUITING","2025-07-18",{"date":32,"type":33},"2025-07-25","ACTUAL",{"date":35,"type":22},"2025-08-01",{"date":37,"type":22},"2028-07-31",{"name":39,"class":40},"Shu-Mei Wang","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":23,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":41},"100579937","effects-of-ras-in-stroke-100579937","NCT06830785","Effects of RAS in Stroke","Effects of Rhythmic Auditory Stimulation on Upper-limb Movements, Function, and Quality of Life in Stroke Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* (1) Diagnosed with either ischaemic or hemorrhagic stroke, and a first-time occurrence;\n* (2) A unilateral stroke;\n* (3) The onset occurred six months or more prior to the experiment, indicating a chronic stage of stroke;\n* (4) The affected upper limb's proximal and distal joints are between Brunnstrom stages four to six, ensuring that the affected limb can execute the upper-limb functional movement training of this study;\n* (5) The affected upper limb's Modified Ashworth Scale score is ≤ 2, indicating no significant muscle stiffness (spasticity) in the affected limb;\n* (6) A Montreal Cognitive Assessment score of ≥ 24, ensuring comprehension of the instructions given during this study;\n* and (7) when we clap hands next to the affected ear of the participant who closes eyes, the participant is able to indicate the sound's source either verbally or through gestures, indicating no complete hearing loss in the affected ear and the ability to receive rhythmic auditory stimulation.\n\nExclusion Criteria:\n\n* (1) Neurological diseases or medical conditions that affect upper-limb movements or hearing;\n* (2) Being participating in other experimental studies related to drug treatment or upper-limb movement therapy.",{"count":50,"type":22},68,[25],"The goal of this study is to to examine whether rhythmic auditory stimulation improved movement speed, movement function of executing activities of daily living, and movement recovery of the affected upper limb, as well as quality of life in stroke patients. The main questions it aims to answer are:\n\n* Does rhythmic auditory stimulation improve movement speed in stroke patients?\n* Does rhythmic auditory stimulation improve movement function of executing activities of daily living in stroke patients?\n* Does rhythmic auditory stimulation improve movement recovery of the affected upper limb in stroke patients?\n* Does rhythmic auditory stimulation improve quality of life in stroke patients?\n\nResearchers will compare movement training with the aid of rhythmic auditory stimulation to movement training without the aid of rhythmic auditory stimulation to see if rhythmic auditory stimulation works to improve movement speed, movement function of executing activities of daily living, and movement recovery of the affected upper limb, as well as quality of life in stroke patients.\n\nParticipants will:\n\n* Undergo movement tests and fill out questionnaires before and after the movement training program\n* Receive movement training for 40 minutes per session and three sessions per week for a total of 24 sessions",[54],"Stroke","RECRUITING","2025-06-19",{"date":58,"type":33},"2025-06-25",{"date":60,"type":33},"2025-03-26",{"date":62,"type":22},"2026-12-31",{"name":39,"class":40},""]