[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Sveti Ivan Psychiatric Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":40},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100656704","compulsive-gambling-efficacy-of-deep-transcranial-magnetic-stimulation-with-h7-coil-100656704",false,"NCT07828782","COMpulsive Gambling: Efficacy of DEEP Transcranial Magnetic Stimulation With H7 COIL","COMET-7","Inclusion Criteria:\n\n* confirmed GD diagnosis according to ICD-10 (F63.0)\n* age between 18 and 64 years\n* male gender\n* enrolled in GD treatment at the GD-DH of the UPC Sveti Ivan within two weeks of study inclusion.\n* right-hand dominance\n\nExclusion Criteria:\n\n* diagnosis of a schizophrenia spectrum disorder (ICD-10, F20-F29)\n* diagnosed psychotic episode within six months prior to inclusion\n* current suicidality\n* clinically relevant neurological disorder or history of cerebrovascular insult\n* diagnosis of a mental and behavioral disorder due to the use of psychoactive substances (ICD-10, F10-F19) (except nicotine dependence)\n* diagnosed moderate or severe dementia\n* presence of intracranial implants\n* inability to independently complete questionnaires\n* refusal to participate due to discomfort during DLPFC localization","MALE","18 Years","64 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to investigate whether a treatment called high-frequency repetitive transcranial magnetic stimulation (rTMS) can help reduce the symptoms of gambling disorder and whether it is safe and well tolerated.\n\nThe study will include 60 men aged 18-64 years who have been diagnosed with gambling disorder and are starting treatment at the Gambling Disorder Day Hospital of UPC Sveti Ivan in Zagreb.\n\nParticipants will be randomly assigned to one of two groups. One group will receive active rTMS treatment using the H7 coil, while the other group will receive a sham (placebo) treatment that looks and feels similar but does not provide the active magnetic stimulation. Neither the participants nor the researchers assessing the results will know which treatment each participant received during the study. All participants will continue to receive their usual treatment.\n\nThe study will last six weeks. Participants will complete questionnaires before treatment and six weeks after the intervention. The main goal is to determine whether rTMS reduces the severity of gambling-related symptoms.\n\nThe researchers will also examine whether personal, psychological, and clinical characteristics can help predict who is most likely to benefit from rTMS. In addition, the study will investigate whether rTMS affects autonomic nervous system regulation, measured through heart rate variability (HRV), and will assess the economic impact of this treatment.\n\nOverall, the study is intended to provide better information about the effectiveness, safety, possible predictors of treatment response, effects on the body's regulation, and cost-effectiveness of rTMS for gambling disorder.",[27],"Gambling Disorder","NOT_YET_RECRUITING","2026-09-15",{"date":31,"type":32},"2026-09-18","ACTUAL",{"date":34,"type":21},"2026-10",{"date":36,"type":21},"2027-12",{"name":38,"class":39},"Sveti Ivan Psychiatric Hospital","OTHER",""]