[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Tainan Hospital, Ministry of Health and Welfare\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":84},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,65],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100649628","chaihushugan-decoction-and-wen-dan-tang-for-insomnia-100649628",false,"NCT07735390","Chaihushugan Decoction and Wen Dan Tang for Insomnia","Effectiveness Evaluation of Chaihushugan Decoction and Wen Dan Tang Used in Treating Insomnia: A Pilot Randomized, Head-to-Head Trial","Inclusion Criteria:\n\n* Patients aged 20 or older seeking treatment at the Traditional Chinese Medicine outpatient clinic with sleep disorders.\n* Meet the diagnostic criteria for chronic insomnia according to the International Classification of Sleep Disorders, Third Edition (ICSD-3).\n* Willing to receive traditional Chinese medicine treatment.\n* Able to provide signed informed consent approved by the National Cheng Kung University Hospital Institutional Review Board.\n\nExclusion Criteria:\n\n* Diagnosed with schizophrenia or narcolepsy.\n* History of neurological diseases (e.g., stroke history, neurodegenerative diseases).\n* History of alcohol or drug addiction.\n* Experiencing major, uncontrollable life-altering stressors (e.g., recent bereavement).","ALL","20 Years",{"count":19,"type":20},24,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate the clinical effectiveness of Traditional Chinese Medicine (TCM) in treating sleep disorders, specifically chronic insomnia. While conventional TCM treatments often rely heavily on subjective patient feedback, this clinical trial incorporates objective diagnostic tools, including Digital Polysomnography (PSG) and actigraphy, to gather data-driven sleep quality metrics.\n\nParticipants will be randomly assigned to receive either Chaihushugan Decoction or Wen Dan Tang for an 8-week treatment period. Subjective improvements will be tracked using standardized clinical questionnaires such as the Insomnia Severity Index (ISI) and Pittsburgh Sleep Quality Index (PSQI). The findings from this trial will help clarify the scientific basis and treatment pathways of these two classic herbal formulations for sleep management.",[26,27],"Insomnia","Sleep Wake Disorders",[29],"Chaihushugan Decoction","RECRUITING","2026-08-04",{"date":33,"type":34},"2026-08-07","ACTUAL",{"date":36,"type":34},"2024-09-13",{"date":38,"type":20},"2029-12-31",{"name":40,"class":41},"Tainan Hospital, Ministry of Health and Welfare","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":59,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":42},"100649273","acupoint-stimulation-and-exercise-for-taiwanese-pre-frail-older-adults-100649273","NCT07732530","Acupoint Stimulation and Exercise for Taiwanese Pre-frail Older Adults","Exploring the Associations Among Frailty, Daily Physical Activity, Sleep, and Traditional Chinese Medicine Constitution in Taiwanese Older Adults, and Evaluating the Effects of Acupoint Stimulation Interventions","Inclusion Criteria:\n\n1. Individuals who are capable of undergoing frailty assessments.\n2. Individuals who possess effective communication skills.\n3. Aged 50 years or older.\n4. Willing to provide written informed consent, keep a 7-day sleep diary, and complete related questionnaires.\n5. Identified as pre-frail (frailty score of 1-2 points) according to the frailty phenotype criteria for the clinical trial phase.\n\nExclusion Criteria:\n\n1\\. Individuals who are unwilling or unable to wear an actigraph (wrist monitor) or undergo physical measurements.","50 Years",{"count":52,"type":20},30,[23],"This study aims to explore the relationships between frailty, daily physical activity, sleep quality, and Traditional Chinese Medicine (TCM) constitutions among older adults in Taiwan. In the trial phase, a randomized controlled trial will be conducted specifically for pre-frail older adults. Participants will be randomly assigned to either the exercise training group (Vivifrail program) or the integrated group combining exercise with daytime and sleep-improving acupoint stimulation. The study evaluates the combined efficacy of these non-invasive interventions on reducing frailty severity, improving sleep, and enhancing daily physical functions.",[56,57,58],"Frailty","Sleep Quality","Aging",{"date":33,"type":34},{"date":61,"type":34},"2025-06-03",{"date":63,"type":20},"2027-12-31",{"name":40,"class":41},{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":4,"eligibilityCriteria":70,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":71,"targetDuration":4,"studyType":21,"phases":73,"briefSummary":74,"conditions":75,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":83,"locationsCount":42},"100647943","exploration-on-the-relationship-between-distinct-sarcopenia-traditional-chinese-medicine-body-constitution-and-circadian-rhythm-patterns-of-older-adults-and-impact-of-acupoint-stimulated-interventions-100647943","NCT07715721","Exploration on the Relationship Between Distinct Sarcopenia, Traditional Chinese Medicine Body Constitution, and Circadian Rhythm Patterns of Older Adults and Impact of Acupoint-stimulated Interventions","Inclusion Criteria:\n\n* Participants must be able to understand and sign the informed consent form.\n* For the geriatric cohorts: Individuals aged 65 and above.\n* For the adult cohort: Individuals aged between 20 and 64.\n* For the sleep disturbance cohorts: Presenting with a Pittsburgh Sleep Quality Index (PSQI) score of 5 or higher.\n* For the sarcopenia cohort: Evaluated and diagnosed with sarcopenia according to standard geriatric metrics.\n\nExclusion Criteria:\n\n* Individuals with severe cognitive impairment, advanced dementia, or inability to communicate and follow instructions.\n* Individuals with unstable medical conditions, acute cardiovascular events, or severe systemic diseases that preclude safe participation in exercise programs.\n* Individuals with open wounds, active infections, or fractures at the targeted acupoint areas.\n* Any other conditions that, in the judgment of the investigator, would jeopardize candidate safety or compliance.",{"count":72,"type":20},360,[23],"The purpose of this study is to evaluate the clinical efficacy and impact of digital\u002Fremote courses combining traditional Chinese medicine (TCM) acupoint-stimulated interventions, health education, and exercise on sarcopenia and sleep disturbances across distinct age groups. By integrating multidisciplinary expertise encompassing TCM, geriatric medicine, geriatric health, community medicine, and epidemiology at Ministry of Health and Welfare Tainan Hospital, this project aims to explore the correlations among sarcopenia, sleep conditions, and TCM body constitution, while evaluating the feasibility of incorporating the simplified Body Constitution Questionnaire (BCQ) into anti-frailty screenings to establish an evidence-based, TCM-integrated intervention model. A total of at least 360 participants will be recruited at Ministry of Health and Welfare Tainan Hospital across two distinct operational phases. In the first phase, a comprehensive cross-sectional assessment will be conducted on 300 older adults aged 65 and above to establish a geriatric TCM body constitution database, utilizing 7-day actigraphy, scientific tongue and pulse diagnosis, the BCQ, and standard geriatric functional assessment scales (including SARC-F, Fried frailty index, ADL, IADL, WHOQOL-BREF, EQ-5D, mini nutritional assessment, ISI, PSQI, and ECOG score), with eligible and consenting participants referred for overnight polysomnography (PSG) based on physician assessment. In the second phase, longitudinal interventional trials will be executed with 180 participants divided into three specific cohorts. The sarcopenia cohort, comprising 60 older adults aged 65 and above, will undergo a 3-month intervention combining acupoint massage and the Vivifrail exercise program, with data evaluated at baseline, month 1, and month 3, followed by a final tracking period extending to month 4. The geriatric sleep disturbance cohort (60 older adults aged 65 and above) and the adult sleep disturbance cohort (60 younger adults aged 20-64), all presenting with a Pittsburgh Sleep Quality Index (PSQI) score of 5 or higher, will participate in a 2-week curriculum consisting of sleep-related self-acupoint massage and sleep hygiene education, with clinical follow-ups scheduled at baseline, week 2, and week 6, a final tracking assessment at week 7, and intervention compliance monitoring conducted at week 3.",[76,27],"Sarcopenia","2026-07-23",{"date":79,"type":34},"2026-07-27",{"date":81,"type":34},"2023-05-19",{"date":63,"type":20},{"name":40,"class":41},""]