[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"The Jerzy Kukuczka Academy of Physical Education in Katowice\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":344},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,51,78,113,140,170,204,235,263,289,318],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100652027","the-impact-of-omega-3-fatty-acid-supplementation-on-the-composition-of-erythrocyte-membranes-in-athletes-100652027",false,"NCT07768423","The Impact of Omega-3 Fatty Acid Supplementation on the Composition of Erythrocyte Membranes in Athletes","Effects of Omega-3 Fatty Acid Supplementation on Omega-3 Index, Cognitive Function, Hormonal Profile, Speed, and Endurance in Competitive Athletes Aged 16-35 Years: A Randomized Placebo-Controlled Trial","OMEGA-PERFORM","\\*\\*Inclusion Criteria:\\*\\*\n\n* Male competitive soccer players aged 16-35 years.\n* Regular participation in organized soccer training and competition.\n* A minimum of 6 years of systematic soccer training experience.\n* Participation in regular team training during the study period.\n* Habitual mixed diet.\n* Ability and willingness to maintain usual dietary habits and training load throughout the 4-week intervention.\n* Written informed consent provided by the participant.\n* For participants under 18 years of age, written informed consent provided by a parent or legal guardian and assent provided by the participant.\n\n\\*\\*Exclusion Criteria:\\*\\*\n\n* Current use of omega-3 fatty acid supplements or fish-oil products.\n* Use of omega-3 supplements within the 3 months preceding enrollment.\n* Known allergy or hypersensitivity to fish, seafood, fish oil, or any ingredient of the study supplements.\n* Diagnosed cardiovascular, metabolic, endocrine, gastrointestinal, neurological, inflammatory, autoimmune, or hematological disease.\n* Acute infection, injury, or illness that could affect participation in training or study assessments.\n* Use of medications or dietary supplements that could influence lipid metabolism, inflammatory status, hormonal profile, blood coagulation, cognitive function, or physical performance.\n* Regular use of anticoagulant or antiplatelet medication.\n* Significant change in diet, training volume, or supplementation during the study period.\n* Failure to comply with the supplementation protocol or attendance requirements.\n* Participation in another clinical or nutritional intervention study during the study period.",true,"ALL","16 Years","35 Years",{"count":22,"type":23},200,"ESTIMATED","INTERVENTIONAL",[26],"NA","The aim of this study is to evaluate the effects of omega-3 fatty acid supplementation on the Omega-3 Index, erythrocyte membrane composition, cognitive function, hormonal profile, speed, endurance performance, and hematological parameters in competitive athletes aged 16-35 years.",[29,30,31],"Physical Performance","Cognitive Function","Sports Nutrition",[33,34,35,36,37],"Omega-3 fatty acids","Physical performance","Randomized controlled trial","Erythrocyte membrane fatty acids","Sports nutrition","RECRUITING","2026-08-14",{"date":41,"type":42},"2026-08-17","ACTUAL",{"date":44,"type":42},"2025-01-07",{"date":46,"type":23},"2028-12-31",{"name":48,"class":49},"The Jerzy Kukuczka Academy of Physical Education in Katowice","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":18,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":24,"phases":61,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},"100652229","basal-stimulation-therapy-in-adults-with-schizophrenia-requiring-institutional-care-100652229","NCT07769749","Basal Stimulation Therapy in Adults With Schizophrenia Requiring Institutional Care","The Impact of Basal Stimulation Therapy in Adult Patients With Schizophrenia Requiring Permanent Institutional Care","Study inclusion criteria:\n\n* women and men aged ≥ 55 years,\n* consent of the legal guardian\u002Fcaregiver to participate in the study,\n* schizophrenia clinically confirmed for at least 5 years, with predominance of negative symptoms,\n* stable drug therapy (treatment unchanged for at least 3 months)\n* functional ability of everyday life on the Barthel scale below 40 points.\n\nThe exclusion criteria from the study will be:\n\n* lack of consent to participate in the study;\n* pregnancy\n* general contraindications (acute inflammatory conditions and diseases accompanied by fever, venous thrombosis, unstable arterial hypertension , early condition after contrast-enhanced computed tomography, early condition after lumbar puncture, general serious condition of the patient )\n* exacerbation of the main disease (acute psychosis, severe anxiety, tendency to active aggression, visual seizures)\n* active cancer;\n* diseases of the nervous system (neuropathies, stroke , damage to the cerebellum, labyrinth) causing altered sensitivity to stimuli;\n* diseases and illnesses of the musculoskeletal system that significantly disturb the body's balance and the mobility of the limbs;\n* pressure ulcers grade IV and V on the Torrance scale.","55 Years",{"count":60,"type":23},12,[26],"The aim of the study is to obtain knowledge of the impact of basal stimulation therapy on the health status of adults suffering from schizophrenia and requiring permanent institutional care.\n\nThe use of basal stimulation therapy in many European centres for several decades, combined with the limited amount of scientific evidence, justifies undertaking the proposed research. Available evidence indicates reduced anxiety and improved quality of life. No such studies have previously been conducted in institutionalized patients with schizophrenia.",[64],"SCHIZOPHRENIA 1 (Disorder)",[66,67],"Basal Stimulation Therapy","Schizophrenia","NOT_YET_RECRUITING","2026-08-12",{"date":71,"type":42},"2026-08-18",{"date":73,"type":23},"2026-09-01",{"date":75,"type":23},"2027-12-31",{"name":48,"class":49},2,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":18,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":24,"phases":89,"briefSummary":90,"conditions":91,"keywords":98,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":110,"leadSponsor":111,"locationsCount":112},"100651606","effectiveness-and-costs-of-pressure-ulcer-treatment-and-the-quality-of-life-of-patients-with-pressure-ulcers-receiving-home-based-and-institutional-care-100651606","NCT07763106","Effectiveness and Costs of Pressure Ulcer Treatment and the Quality of Life of Patients With Pressure Ulcers Receiving Home-Based and Institutional Care","Comparative Assessment of the Effectiveness and Costs of Pressure Ulcer Treatment and the Quality of Life of Patients With Pressure Ulcers Receiving Home-Based and Institutional Care","Inclusion Criteria:\n\n* Women and men aged 60 to 90 years,\n* stage II-IV pressure ulcers in the lumbar-sacral area of the trunk, pelvic girdle, and lower limbs,\n* high risk of pressure ulcers (above 15 points on the Waterlow scale),\n* daily functional ability below 40 points on the Barthel scale,\n* consent from the patient or legal guardian\u002Fcaregiver to participate in the study.\n\nExclusion Criteria:\n\n* General contraindications (acute inflammatory conditions and febrile illnesses, venous thrombosis, cachexia),\n* pressure ulcers requiring surgical treatment (black necrosis, inflammation of bones and soft tissues),\n* tunneling pressure ulcers showing signs of acute inflammation,\n* pressure ulcers showing signs of infection (causing fever, swelling, pain, and unpleasant odor),\n* pressure ulcers with a surface area of less than 0.5 cm2,\n* pressure ulcers occurring on the lower legs or feet in patients with acute and chronic venous insufficiency and diabetes,\n* multiple pressure ulcers (\\>2),\n* malignant tumors,\n* decompensated diabetes,\n* end-stage chronic heart failure,\n* end-stage renal disease,\n* mental illness.","60 Years","90 Years",{"count":88,"type":23},80,[26],"A study aimed at comparing the effectiveness of treatment, costs, and quality of life of patients with pressure ulcers in home care and institutional care.\n\nEighty individuals aged 60-90 years with stage II-IV pressure ulcers can participate in the study.\n\nParticipants will be assessed for factors such as health status, independence, mood, and quality of life.\n\nThe study will allow for better tailoring care to patients' needs. Other benefits of participating in the study is that the participants will receive a detailed assessment of their health, nutrition, quality of life, as well as support in managing their pressure ulcers. They will receive regular care and medical evaluations, which may positively impact their health and well-being.\n\nRefusing to participate in this study will not affect the patients treatment in any way.\n\nPlease ask if there is anything that is unclear or if you would like additional information.\n\nTaking part in this study is entirely voluntary.",[92,93,94,95,96,97],"Pressure Ulcer (PU)","Pressure Ulcers, Bedsores, Decubitus Ulcer","Quality of Life","INSTITUTIONAL CARE","Wound Closure","Wound Care",[99,100,101,102,103,104,105],"Pressure Ulcer","Quality of life","Home-Based","Institutional Care","wound care","wound closure","wound treatment","2026-08-09",{"date":108,"type":42},"2026-08-13",{"date":73,"type":23},{"date":75,"type":23},{"name":48,"class":49},3,{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":18,"minAge":120,"maxAge":4,"enrollmentInfo":121,"targetDuration":4,"studyType":24,"phases":123,"briefSummary":124,"conditions":125,"keywords":128,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":137,"leadSponsor":139,"locationsCount":77},"100650393","snoezelen-therapy-in-adults-with-alcohol-dependence-and-adults-with-schizophrenia-100650393","NCT07748078","Snoezelen Therapy in Adults With Alcohol Dependence and Adults With Schizophrenia","Impact of Snoezelen Therapy in Adults With Alcohol Dependence and Adults With Schizophrenia","1. Adults suffering from schizophrenia requiring permanent institutional care, N=40\n\n   Inclusion criteria:\n   * women and men aged ≥ 18 years,\n   * consent of the patient or legal guardian to participate in the study,\n   * schizophrenia clinically confirmed for at least 5 years, with predominance of negative symptoms,\n   * stable drug therapy (treatment unchanged for at least 3 months)\n   * ability to understand and follow the therapist's instructions,\n   * functional ability of everyday life on the Barthel scale below 40 points,\n\n   Exclusion criteria:\n   * lack of consent to participate in the study;\n   * pregnancy;\n   * general contraindications (acute inflammatory and febrile diseases, venous thrombosis, unstable arterial hypertension, early condition after contrast computed tomography, early condition after lumbar puncture, general serious condition of the patient);\n   * unstable or untreated epilepsy, based on EEG;\n   * exacerbation of the main disease (acute psychosis, severe anxiety, tendency to active aggression, etc.);\n   * active cancer disease;\n   * diseases of the nervous system (neuropathies, stroke, damage to the cerebellum, labyrinth, Parkinson's disease) causing altered sensitivity to stimuli;\n   * diseases and illnesses of the musculoskeletal system that disturb the body's balance and the mobility of the limbs.\n2. Adults (men) suffering from schizophrenia, N=40\n\n   Inclusion criteria:\n   * men aged ≥ 18 years,\n   * consent of the patient or legal guardian to participate in the study,\n   * clinically confirmed schizophrenia with predominance of negative symptoms,\n   * stable drug therapy (treatment unchanged for at least 1 month),\n   * ability to understand and follow the therapist's instructions,\n   * functional ability of everyday life on the Barthel scale above 40 points,\n\n   Exclusion criteria:\n   * lack of consent to participate in the study;\n   * general contraindications (acute inflammatory and febrile diseases, venous thrombosis, unstable arterial hypertension, early condition after contrast computed tomography, early condition after lumbar puncture, general serious condition of the patient);\n   * unstable or untreated epilepsy, based on EEG;\n   * exacerbation of the main disease (acute psychosis, severe anxiety, tendency to active aggression, etc.);\n   * active cancer disease;\n   * diseases of the nervous system (neuropathies, stroke, damage to the cerebellum, labyrinth, Parkinson's disease) causing altered sensitivity to stimuli; diseases and illnesses of the musculoskeletal system disturbing body balance and limb mobility.\n3. Adults (women) addicted to alcohol, N= 60\n\nInclusion criteria:\n\n* female gender;\n* age ≥ 18 years;\n* consent of the patient or legal guardian to participate in the study;\n* alcohol dependence syndrome (F10.2 according to ICD-10);\n* history of depressive and anxiety symptoms;\n* ability to understand and follow the therapist's instructions;\n* functional ability of everyday life on the Barthel scale above 40 points.\n\nExclusion criteria:\n\n* lack of consent to participate in the study;\n* pregnancy;\n* psychoactive substances other than alcohol;\n* exacerbation of the main disease (acute psychosis, severe anxiety, tendency to active aggression, etc.);\n* mental illnesses other than depression and anxiety disorders;\n* psychotic diseases (F20- schizophrenia and other schizophrenic disorders);\n* general contraindications (acute inflammatory and febrile diseases, venous thrombosis, unstable arterial hypertension, early condition after contrast computed tomography, early condition after lumbar puncture, general serious condition of the patient);\n* unstable or untreated epilepsy, based on EEG;\n* active cancer disease;\n* diseases of the nervous system (neuropathies, stroke, damage to the cerebellum, labyrinth, Parkinson's disease) causing altered sensitivity to stimuli;\n* severe cognitive impairment;\n* diagnosis of autism and ADHD;\n* PTSD;\n* intellectual disability (diagnosis F70 - F79);\n* diseases and illnesses of the musculoskeletal system that disturb the body's balance and the mobility of the limbs.","18 Years",{"count":122,"type":23},140,[26],"The purpose of the study: obtaining knowledge about the impact of Snoezelen® therapy on the health of adults suffering from schizophrenia and requiring permanent institutional care, adults suffering from schizophrenia and adults (women) addicted to alcohol.\n\nThe main questions it aims to answer are:\n\nDoes Snoezelen therapy improve the health of adults suffering from schizophrenia and requiring permanent institutional care, adults suffering from schizophrenia and adults (women) addicted to alcohol?\n\nThe participant will participate in Snoezelen® therapy for 6 or 12 weeks, 2 times a week (30 minutes each session).",[64,126,127],"Alcohol Use Disorder","Alcohol Dependence (Primary Condition)",[129,130,131,132],"Snoezelen® therapy","Snoezelen","alcohol dependence","schizophrenia","2026-07-31",{"date":135,"type":42},"2026-08-05",{"date":73,"type":23},{"date":138,"type":23},"2027-12-30",{"name":48,"class":49},{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":4,"eligibilityCriteria":146,"healthyVolunteers":17,"sex":147,"minAge":148,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":24,"phases":152,"briefSummary":153,"conditions":154,"keywords":158,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":167,"leadSponsor":169,"locationsCount":77},"100649607","impact-of-respiratory-training-on-reaction-time-and-other-performance-components-in-young-football-players-100649607","NCT07737379","Impact of Respiratory Training on Reaction Time and Other Performance Components in Young Football Players.","The Impact of Respiratory Training on Reaction Time and Other Components of Performance in Young Football Players.","Inclusion Criteria 50 healthy boys aged 13-15 (born between 2011 and 2013) who:\n\n* are training in football for at least 2 years;\n* have a valid medical clearance to practice football,\n* nave an active membership in the MTS Rybnik Football Academy,\n* have parental\u002Fcaregiver consent for the participation in the study,\n* give an informed consent to participate in the study,\n* did not participate in respiratory or other breathing training over the past year,\n* are attending the training sessions during the 6 months prior to the study at a level of at least 80% of scheduled hours.\n\nExclusion Criteria:\n\n* no valid medical clearance to practice football,\n* currently occurring acute (including respiratory infections) or chronic diseases that may affect sport endurance and safety of training,\n* musculoskeletal injuries requiring treatment or limiting participation in football training, sustained within the 6 months prior to participation in the study,\n* illnesses requiring hospitalization within the 6 months prior to participation in the study,\n* neurological or musculoskeletal conditions requiring physiotherapy within the 6 months prior to participation in the study,\n* diagnosed respiratory diseases (e.g., pharmacologically uncontrolled asthma), cardiovascular diseases, or other conditions constituting a contraindication to sports and physical exertion,\n* contraindications to performing breathing and respiratory exercises, such as: a tendency toward hyperventilation, dizziness during breathing exercises, or recent chest injuries.","MALE","13 Years","15 Years",{"count":151,"type":23},50,[26],"The overall aim of the study is to gain knowledge about the impact of respiratory training on reaction time and other components of performance in young football players.",[155,156,157],"Training Effectiveness","Training Efficiency","Football Players",[159,160,161,162],"repiratory training","reaction time","football players","soccer players","2026-07-27",{"date":165,"type":42},"2026-07-30",{"date":73,"type":23},{"date":168,"type":23},"2027-06-30",{"name":48,"class":49},{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":176,"eligibilityCriteria":177,"healthyVolunteers":17,"sex":18,"minAge":178,"maxAge":179,"enrollmentInfo":180,"targetDuration":4,"studyType":182,"phases":4,"briefSummary":183,"conditions":184,"keywords":187,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":50},"100647432","somatic-and-psychological-profile-of-athletes-across-seasonal-cycles-100647432","NCT07709273","Somatic and Psychological Profile of Athletes Across Seasonal Cycles","Somatic and Psychological Profiles of Athletes Across Seasonal Cycles","ASPeC","Inclusion Criteria\n\n* Male or female athletes.\n* Age 14 to 38 years.\n* Participation in a team sport, including football, volleyball, or ice hockey.\n* Regular training experience of at least 5 years.\n* Current membership in a sports club.\n* Valid medical clearance confirming no contraindications to sport participation.\n* Ability to understand the study procedures and complete study questionnaires.\n* Willingness to provide informed consent.\n* For participants under 18 years of age, written consent from a parent or legal guardian.\n\nExclusion Criteria\n\n* Does not meet one or more inclusion criteria.\n* Pregnancy, due to exposure to ionizing radiation in adult participants undergoing DEXA.\n* Refusal or inability to provide informed consent.\n* For minors, absence of parental or legal guardian consent.\n* Any medical or organizational condition that, in the investigators' opinion, would prevent safe participation or valid completion of the study procedures.\n\nDEXA will be performed only in adult participants.","14 Years","38 Years",{"count":181,"type":23},300,"OBSERVATIONAL","This observational longitudinal study will examine the somatic and psychological profile of team sport athletes across seasonal training cycles. The study will include male and female athletes who play football, volleyball, or ice hockey. The planned study population consists of 300 participants, including 200 adults aged 18 to 38 years and an additional 100 adolescent athletes aged 14 to 17 years.\n\nParticipants will be assessed at two time points, before and after a transitional period in the annual training cycle, such as the off-season, holiday break, preparatory period, or competitive period. These periods are associated with changes in training load, recovery, daily routine, and lifestyle, and may therefore influence both body composition and psychological functioning. The longitudinal design will allow evaluation of changes over time and identification of factors associated with more favorable or less favorable adaptations.\n\nThe study will assess body composition and selected behavioral and psychological characteristics. Adult participants will undergo body composition assessment using bioelectrical impedance analysis and dual-energy X-ray absorptiometry (DEXA). Adolescent participants included under the approved amendment will undergo the same study procedures except for DEXA. All participants will complete standardized self-report questionnaires assessing eating behavior, physical activity, sport-related perfectionism, and body esteem.\n\nThe questionnaires used in the study include the Three-Factor Eating Questionnaire (TFEQ-13), the International Physical Activity Questionnaire (IPAQ), the sport perfectionism questionnaire, and the Body Esteem Scale. These tools will be used to examine whether eating behaviors, activity patterns outside formal training, perfectionism, and body image are associated with changes in body composition and related characteristics across different phases of the sports season.\n\nThe main goal of the study is to improve understanding of how seasonal changes in training and daily habits affect the physical and psychological characteristics of athletes. The results may help identify factors linked to beneficial or unfavorable changes in body composition and well-being, and may support the development of more individualized monitoring, nutrition, training, and psychological support strategies for athletes.\n\nParticipation in the study is voluntary. All participants, and legal guardians in the case of minors, will receive information about the study procedures, potential risks, and study aims before consent is obtained. Data will be handled confidentially and analyzed in anonymized form. Study findings are intended for scientific publication and for practical application in athlete monitoring and care.",[185,186],"Eating Behavior","Perfectionism",[188,189,190,191,192,193,194,195],"athletes","team sports","body composition","seasonal variation","eating behavior","physical activity","perfectionism","body esteem","2026-07-14",{"date":198,"type":42},"2026-07-16",{"date":200,"type":42},"2026-03-02",{"date":202,"type":23},"2028-12-29",{"name":48,"class":49},{"id":205,"slug":206,"hasResults":11,"nctId":207,"briefTitle":208,"officialTitle":209,"acronym":210,"eligibilityCriteria":211,"healthyVolunteers":17,"sex":18,"minAge":120,"maxAge":85,"enrollmentInfo":212,"targetDuration":4,"studyType":24,"phases":213,"briefSummary":214,"conditions":215,"keywords":220,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":230,"completionDateStruct":232,"leadSponsor":234,"locationsCount":77},"100644813","dietary-macronutrients-and-gut-microbiota-inflammation-and-metabolic-markers-100644813","NCT07672691","Dietary Macronutrients and Gut Microbiota, Inflammation, and Metabolic Markers","Effects of Diets Differing in Macronutrient Composition on Gut Microbiota Composition, Intestinal Inflammation Markers, Gene Expression Profiles, and Blood Biochemical Parameters in Diverse Populations.","DIETMICRO","Inclusion Criteria:\n\nIn addition to the physical activity requirements described above, the study will include men and women aged 18-60 years with:\n\nBMI not exceeding 40kg\u002Fm²\n\nHabitual mixed diet prior to study enrollment\n\nNormal blood pressure\n\n* Exclusion Criteria:\n\nPoprawiłem już \\*\\*Exclusion Criteria\\*\\* w poprzedniej odpowiedzi - wszystkie te kryteria już tam są wpisane. Oto pełna, ostateczna wersja z wszystkimi wskazanymi kryteriami wyłączenia:\n\n\\*\\*\\* \\*\\*Exclusion Criteria:\\*\\*\n\n* Use of medications regulating \\*\\*glucose levels\\*\\* (e.g., metformin) or \\*\\*blood lipids\\*\\* (e.g., \\*\\*statins\\*\\*)\n* \\*\\*Hypertension\\*\\* or pharmacological treatment for hypertension\n* Diagnosed \\*\\*gastrointestinal disorders\\*\\*, including:\n* Gastric and duodenal ulcers\n* \\*\\*Irritable bowel syndrome (IBS)\\*\\*\n* \\*\\*Ulcerative colitis\\*\\*\n* \\*\\*Celiac disease\\*\\*\n* Chronic use of medications such as:\n* \\*\\*Mesalazine\\*\\*\n* \\*\\*Corticosteroids\\*\\*\n* \\*\\*Statins\\*\\*\n* \\*\\*Proton pump inhibitors (PPI)\\*\\*\n* \\*\\*Non-steroidal anti-inflammatory drugs (NSAIDs)\\*\\*\n* \\*\\*Anticonceptional medications\\*\\*\n* \\*\\*Any supplements\\*\\*\n* \\*\\*Alcohol consumption\\*\\* \\> 2 times\u002Fweek with \\> 15 g alcohol per occasion (approximately 15 g alcohol = 330 mL beer, 150 mL dry red wine, or 50 mL vodka)\n* \\*\\*Smoking cigarettes\\*\\*\n* Following a \\*\\*ketogenic diet\\*\\* or \\*\\*vegetarian diet\\*\\* within \\*\\*1 month\\*\\* prior to study enrollment",{"count":22,"type":23},[26],"Poniżej znajduje się bardziej płynna i mniej powtarzalna wersja tekstu:\n\nThis 12-week randomized controlled trial will investigate the effects of dietary patterns with different macronutrient compositions on gut microbiota, intestinal inflammation, gene expression, and metabolic health in healthy adults.\n\nParticipants will be randomly assigned to one of three dietary interventions: a ketogenic diet (KD), a vegetarian diet (VD), or a control diet (CD) reflecting their habitual mixed dietary pattern. Adherence to the assigned diet will be monitored through dietary records and regular nutritional counseling.\n\nThe study will evaluate changes in gut microbiota composition, inflammatory biomarkers, transcriptomic profiles, and blood biochemical parameters associated with lipid and glucose metabolism. Blood and stool samples will be collected at predefined time points throughout the intervention, while participants in the KD group will additionally undergo ketone monitoring to assess dietary compliance.\n\nBy comparing the ketogenic and vegetarian diets with a standard mixed diet, this study aims to determine their effects on gut health, metabolic function, and systemic inflammation, thereby providing evidence to inform dietary recommendations.\n\nTa wersja eliminuje powtórzenia (\"diet\", \"study\", \"monitor\", \"effects\"), jest bardziej naturalna stylistycznie i odpowiada standardowi językowemu publikacji w czasopismach z zakresu żywienia i medycyny.",[216,217,218,219],"Nutrition","Ketogenic Diet","Gene Expression","Diet",[221,222,223,224,225,226],"ketogenic diet","gene expression","transcriptomics","biochemical parameters","stool microbiome","ketone bodies","2026-07-01",{"date":229,"type":42},"2026-07-02",{"date":231,"type":42},"2024-09-02",{"date":233,"type":23},"2028-12-30",{"name":48,"class":49},{"id":236,"slug":237,"hasResults":11,"nctId":238,"briefTitle":239,"officialTitle":240,"acronym":4,"eligibilityCriteria":241,"healthyVolunteers":17,"sex":18,"minAge":242,"maxAge":85,"enrollmentInfo":243,"targetDuration":4,"studyType":24,"phases":244,"briefSummary":245,"conditions":246,"keywords":249,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":262,"locationsCount":50},"100643004","effects-of-high-dose-vitamin-d-on-hormones-neuromuscular-function-cognition-and-body-composition-in-athletes-100643004","NCT07641075","Effects of High-Dose Vitamin D on Hormones, Neuromuscular Function, Cognition, and Body Composition in Athletes","The Effect of High-dose Vitamin D Supplementation on Selected Hormone Concentrations, Neuromuscular Transmission, Athletic Performance, Cognitive Functions, and Body Composition in Athletes.","Inclusion Criteria:\n\n* a minimum of 8 years of training experience,\n* absence of injuries in the 6 months leading up to the assessments,\n* consistent engagement in training sessions a minimum of 5 times per week over the last 6 months.\n\nExclusion Criteria:\n\n* vitamin D supplementation within one month prior to the study,\n* use of multivitamin supplements,\n* intestinal disorders.","17 Years",{"count":22,"type":23},[26],"This study aims to evaluate the effects of high-dose vitamin D3 supplementation on selected physiological, neuromuscular, and cognitive parameters in athletes. At the baseline visit, participants will undergo a series of assessments at the Functional Research Laboratory at AWF Katowice, including a 10 mL venous blood sample collection, body composition analysis (via InBody and DEXA scans), neuromuscular function evaluation using tensiomyography (TMG), and computerized cognitive tests via the Vienna Test System.\n\nFollowing baseline testing, participants will be randomly assigned to either the vitamin D3 group or the placebo group. The active group will receive a daily dose of 4,000 IU of vitamin D3 (1 capsule with dinner), while the control group will receive an identical placebo. The intervention period will last for 4 or 8 weeks. Upon completion of the supplementation period, all baseline assessments will be repeated to evaluate the post-intervention changes.",[247,248],"Vitamin D 25-Hydroxylase Deficiency","Vitamin D Deficiency\u002FInsufficiency",[250,188,251,252,253,254,255],"vitamin D","coggnitive function","neuro-muscular function","hormones","speed","performance","2026-06-08",{"date":258,"type":42},"2026-06-11",{"date":260,"type":42},"2025-07-01",{"date":46,"type":23},{"name":48,"class":49},{"id":264,"slug":265,"hasResults":11,"nctId":266,"briefTitle":267,"officialTitle":268,"acronym":269,"eligibilityCriteria":270,"healthyVolunteers":17,"sex":18,"minAge":120,"maxAge":4,"enrollmentInfo":271,"targetDuration":273,"studyType":182,"phases":4,"briefSummary":274,"conditions":275,"keywords":277,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":50},"100638516","prevalence-of-musculoskeletal-disorders-among-musicians-100638516","NCT07600437","Prevalence of Musculoskeletal Disorders Among Musicians","Assessment of the Prevalence of Playing-related Musculoskeletal Disorders Among Instrumental Musicians","nill","Inclusion Criteria:\n\n* consent to participate in the study,\n* over 18 years of age,\n* professionally active musician - instrumentalist or musician-hobbyist not working as a professionalist musician\n\nExclusion Criteria:\n\n* lack of consent to participate in the study, age under 18,\n* artist - singer,\n* pregnancy,\n* active cancer,\n* acute viral, bacterial or other infections,\n* current exacerbation of chronic diseases or other conditions that may affect playing the instrument (e.g. osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, fibromyalgia, etc.),\n* previous surgeries and serious injuries of the musculoskeletal system (e.g. road accidents) within the last 5 years.",{"count":272,"type":23},450,"1 Day","Research conducted at the Faculty of Physiotherapy, Academy of Physical Education in Katowice, examines musculoskeletal disorders among instrumental musicians.\n\nThe study protocol was approved by the Ethics Committee of Polish Physiotherapy Associationon (Resolution No. 05\u002F06\u002F2025) on June 11, 2025.\n\nThe application form includes QuickDASH software enabling the functioning of the system and the MPIIQM-P system, which monitors the functioning of the musculoskeletal system and its impact on everyday musical performance.",[276],"Musckloskeletal US",[278,279,280],"Playing-related Musculoskeletal Disorders","PRMDs","musicians","2026-05-13",{"date":283,"type":42},"2026-05-20",{"date":285,"type":42},"2025-06-01",{"date":287,"type":23},"2026-06-30",{"name":48,"class":49},{"id":290,"slug":291,"hasResults":11,"nctId":292,"briefTitle":293,"officialTitle":294,"acronym":4,"eligibilityCriteria":295,"healthyVolunteers":17,"sex":18,"minAge":296,"maxAge":297,"enrollmentInfo":298,"targetDuration":4,"studyType":24,"phases":300,"briefSummary":301,"conditions":302,"keywords":304,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":311,"lastUpdatePostDateStruct":312,"startDateStruct":314,"completionDateStruct":316,"leadSponsor":317,"locationsCount":4},"100615795","temporomandibular-joints-mobility-and-head-posture-influence-of-manual-therapy-and-exercises-in-dental-patients-100615795","NCT07297251","Temporomandibular Joints Mobility and Head Posture: Influence of Manual Therapy and Exercises in Dental Patients.","Assessment of Temporomandibular Joint Mobility With Different Head Postures. Analysis of the Influence of Selected Manual Therapy Techniques on Temporomandibular Joint Mobility and Head Posture.","Inclusion Criteria:\n\n* Patients aged 11 to 13 years with a confirmed occlusion class (Class I, II, or III) with parental\u002Flegal guardian consent.\n* Patients aged 13 to 17 years with personal assent and parental\u002Flegal guardian consent.\n* Adult patients (up to 65 years of age) who have provided informed consent.\n\nExclusion Criteria:\n\n* Inability to perform required study tests or procedures.\n* Positive safety tests indicating contraindications to manual intervention.\n* History of surgeries or trauma to the maxillofacial region.\n* Genetic defects or neurological disorders.\n* Current orthodontic treatment with fixed appliances.\n* Current splint therapy.\n* Pregnancy.\n* Lack of consent from a parent or legal guardian (for minors).\n* Lack of cooperation from the participant (especially children).","11 Years","65 Years",{"count":299,"type":23},100,[26],"Goal: This clinical study aims to investigate how the range of motion of the temporomandibular joints (TMJ) changes in relation to the patient's head posture. Furthermore, we will assess the efficacy of a specific physiotherapy program in improving TMJ mobility and influencing head alignment in patients undergoing orthodontic treatment or prosthetic reconstruction.\n\nScope: The project will evaluate TMJ function and head alignment in orthodontic or prosthetic patients aged 11-65. The core focus is to analyze the correlation between head posture and TMJ mobility and to measure changes in these parameters before and after the manual physiotherapy intervention.",[303],"Temporomandibular Joint Disorders",[305,306,307,308,309,310],"temporomandibular joint","range of motion","cervical spine","kinematic","manual therapy","exercices","2025-12-19",{"date":313,"type":42},"2025-12-22",{"date":315,"type":23},"2026-01-20",{"date":138,"type":23},{"name":48,"class":49},{"id":319,"slug":320,"hasResults":11,"nctId":321,"briefTitle":322,"officialTitle":323,"acronym":4,"eligibilityCriteria":324,"healthyVolunteers":11,"sex":18,"minAge":325,"maxAge":19,"enrollmentInfo":326,"targetDuration":4,"studyType":24,"phases":327,"briefSummary":328,"conditions":329,"keywords":331,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":337,"lastUpdatePostDateStruct":338,"startDateStruct":340,"completionDateStruct":341,"leadSponsor":343,"locationsCount":77},"100589816","influence-of-sensory-stimulation-on-sensory-parameters-and-motor-function-in-children-with-developmental-coordination-disorder-100589816","NCT06959329","Influence of Sensory Stimulation on Sensory Parameters and Motor Function in Children With Developmental Coordination Disorder","The Influence of Intensified Sensory Stimulation on Upper Extremity Sensory Parameters and Motor Function in Children With Developmental Coordination Disorder","Inclusion Criteria:\n\n* between 12-16 years of age\n* diagnosed severe symptoms of the developmental coordination disorder based on The Movement Assessment Battery for Children 2nd Edition (M-ABC 2), with scores ranging from 40 to 50\n* typical intellectual development (i.e., children attending mainstream education)\n* voluntary participation and informed consent signed by parents or legal guardians\n\nExclusion Criteria:\n\n* current or previous diagnosis of serious orthopaedic or neurological conditions (e.g. fractures, congenital deformities, cerebral palsy, etc.)\n* history of any surgical procedures\n* history of significant musculoskeletal pain or dysfunction lasting more than two weeks and requiring medical or physiotherapeutic intervention, or any such symptoms occurring within one month prior to the study\n* any current musculoskeletal dysfunction and\u002For pain\n* body mass index exceeding 22 kg\u002Fm³","12 Years",{"count":88,"type":23},[26],"The goal of this clinical trial is to evaluate whether intensive sensory stimulation therapy can improve upper limb motor skills and sensory function in children aged 12-16 years with severe symptoms of Developmental Coordination Disorder (DCD). The main questions it aims to answer are:\n\n1. Will children with DCD who undergo intensive sensory stimulation therapy show greater improvement in upper limb motor function compared to those receiving standard therapy?\n2. Will intensive sensory stimulation therapy lead to better sensory function outcomes, including joint position sense, resistance sense, pressure sense, temperature perception, and two-point discrimination? Researchers will compare children receiving intensive sensory stimulation therapy to those receiving standard therapy without intensive sensory stimulation to see if the targeted intervention results in superior improvements in motor and sensory function.",[330],"Developmental Coordination Disorder",[332,333,334,335,336],"developmental coordination disorder","sensory function","motor function","sensory stimulation","adolescents","2025-05-07",{"date":339,"type":42},"2025-05-13",{"date":285,"type":23},{"date":342,"type":23},"2026-04-30",{"name":48,"class":49},""]