[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidad Autonoma del Estado de Mexico\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":87},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,58],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":57},"100651370","physiological-changes-in-adult-intensive-care-patients-following-contact-with-their-primary-caregiver-100651370",false,"NCT07761364","Physiological Changes in Adult Intensive Care Patients Following Contact With Their Primary Caregiver","Physiological Changes in Adult Intensive Care Patients Upon Contact With Their Primary Caregiver (CARE-ICU): A Randomized Clinical Trial","CARE-ICU","Inclusion Criteria\n\nPatient Criteria:\n\n* Adults aged 18 years or older.\n* Admission to the intensive care unit (ICU) for 24 to 48 hours.\n* Richmond Agitation-Sedation Scale (RASS) score between -3 and -1 or between 0 and +3.\n* Glasgow Coma Scale score greater than 13.\n\nPrimary Caregiver Criteria:\n\n* Identified as the patient's primary caregiver.\n* Willing and able to participate in the study.\n* Provides written informed consent prior to study participation.\n\nExclusion Criteria\n\nPatient Criteria:\n\n* Diagnosis of a neurological disorder (e.g., cerebrovascular disease or stroke).\n* Multiple organ dysfunction syndrome (MODS).\n* Unstable or difficult-to-control cardiac arrhythmias.\n* Fever (body temperature ≥ 37.5°C) at the time of assessment.\n* Hypertension (blood pressure ≥ 130\u002F80 mmHg) at the time of assessment.\n\nPrimary Caregiver Criteria:\n\n\\- Unable to be present to perform the intervention according to the study protocol.","ALL","18 Years","59 Years",{"count":21,"type":22},80,"ESTIMATED","INTERVENTIONAL",[25],"NA","Patients admitted to intensive care units are exposed to multiple environmental and clinical factors that may affect their physiological responses. This randomized controlled trial aims to evaluate the effect of physical contact with the primary caregiver on physiological parameters in adult patients hospitalized in an intensive care unit.",[28,29],"Critical Illness","Critically Ill Patients",[31,28,29,32,33,34,35,36,37,38,39,40,41,42,43,44],"Intensive Care Unit","Primary Caregiver","Family Caregive","Therapeutic Touch","Physical Contact","Human Touch","Physiological Parameters","Physiological Response","Heart Rate","Blood Pressure","Respiratory Rate","Oxygen Saturation","Critical Care Nursing","Patient-Centered Care","RECRUITING","2026-08-10",{"date":48,"type":49},"2026-08-12","ACTUAL",{"date":51,"type":49},"2026-08-01",{"date":53,"type":22},"2026-08-31",{"name":55,"class":56},"Universidad Autonoma del Estado de Mexico","OTHER",1,{"id":59,"slug":60,"hasResults":11,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":17,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":4,"studyType":23,"phases":69,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":57},"100640913","application-of-neuro-electrostimulation-as-a-treatment-for-patients-with-dry-mouth-100640913","NCT07593495","Application of Neuro-electrostimulation as a Treatment for Patients With Dry Mouth","Inclusion Criteria:\n\n* Patients diagnosed with dry mouth symptoms.\n* Patients who wish to participate in the study.\n* Patients who allow saliva samples to be collected before, during, and after treatment.\n* Patients who allow the application of transcutaneous electrical nerve stimulation (TENS).\n* Patients who do not have any active oral infections.\n* Patients who attend all sialometry assessments and physiotherapy sessions and complete both quality of life questionnaires (initial and final).\n\nExclusion Criteria:\n\n* Patients with any other mucosal alteration.\n* Patients who do not wish to participate in the study.\n* Patients who do not allow the collection of saliva samples.\n* Patients who do not allow the application of transcutaneous electrical nerve stimulation (TENS).\n* Patients with any infectious process in the oral cavity.\n* Because the study requires the use of low-frequency pulse currents, participants with pacemakers, defibrillators, hearing aids, or cochlear implants will also be excluded from the study.",true,"12 Years","90 Years",{"count":68,"type":22},35,[25],"Hyposalivation is a condition that has increased in frequency, primarily due to the degeneration of salivary glands caused by aging, polypharmacy, chronic or autoimmune diseases, or radiation treatments. Most of these factors are associated with the elderly, a growing demographic due to the aging population. Therefore, addressing this condition has become crucial in our population, as has understanding how it affects their quality of life. Given that saliva plays a vital role in maintaining the oral mucosa, tooth structure, initiating digestion, and even speech, a long-term treatment to stimulate salivary production would be extremely helpful in resolving these problems. Currently, only palliative measures that temporarily cover or lubricate the oral cavity and its structures are available.\n\nAmong the most innovative treatments is neuroelectrical stimulation (TENS) as an adjunct in the therapy of dry mouth, which has shown improvement; however, this improvement has not been quantified through objective measurements that would allow for determining the quantity and quality of saliva, nor in the long term. Likewise, the patient's quality of life affected by this condition has not been assessed.\n\nTherefore, the objective of this project is to evaluate the effect on salivary quality and quantity after the application of neuroelectrical stimulation as a treatment for patients with dry mouth, as well as their quality of life.",[72],"Saliva Altered",[74,75,76,77,78],"Saliva","Salivation","Xerostomia","Quality of life","Physical Therapy Modalities","2026-05-13",{"date":81,"type":49},"2026-05-18",{"date":83,"type":49},"2026-02-01",{"date":85,"type":22},"2027-07-31",{"name":55,"class":56},""]