[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidade Ceuma\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100641661","effect-of-enamel-cleaning-on-a-remineralizing-paste-for-hypomineralizated-lesions-100641661",false,"NCT07653373","Effect of Enamel Cleaning on a Remineralizing Paste for Hypomineralizated Lesions","The Effect Of Deproteinization On The Performance Of CPP-ACPF On Hypomineralized Enamel: A Clinical Evaluation","ECLIPSE","Inclusion Criteria:\n\n* Children with at least one permanent molar without MIH.\n* At least two permanent molars with mild MIH lesions (demarcated opacities without structural loss)\n* Lesions may be with or without sensitivity\n* Lesions cream-white or yellowish in color\n* Lesions ≥ 2 mm in diameter\n* Lesions may be on the same or different dental arches\n\nExclusion Criteria:\n\n* Visible bacterial biofilm\n* Enamel malformations associated with syndromes\n* Amelogenesis imperfecta\n* Fluorosis\n* Allergy to milk proteins (casein)",true,"ALL","7 Years","9 Years",{"count":22,"type":23},54,"ESTIMATED","INTERVENTIONAL",[26],"NA","Molar-incisor hypomineralization (MIH) is a qualitative defect of dental enamel, in which low mineral content and high protein content compromise the effectiveness of remineralizing treatments. Various agents have been used to remove proteins from hypomineralized enamel, such as sodium hypochlorite (NaOCl). Sodium hypochlorite is an antimicrobial irrigant capable of dissolving tissues. The amorphous calcium fluoride casein phosphate phosphopeptide (CPP-ACPF) is used as a remineralizing agent for MIH lesions, it is capable of stabilizing calcium, phosphate, and fluoride ions on the tooth surface, maintaining them in an amorphous form. Therefore, the objective of this study is to evaluate the clinical performance of CPP-ACPF dental mousse on deproteinized hypomineralized enamel.",[29],"Molar Incisor Hypomineralization",[31,32,33,34],"molar hypomineralization","dental enamel","spectrophotometry","dental remineralization","NOT_YET_RECRUITING","2026-07-06",{"date":38,"type":39},"2026-07-08","ACTUAL",{"date":41,"type":23},"2026-08",{"date":43,"type":23},"2028-04",{"name":45,"class":46},"Universidade Ceuma","OTHER",""]