[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidade Federal de Santa Maria\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":47},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100659857","therapeutic-ultrasound-for-muscle-recovery-after-muscle-fatigue-exercise-100659857",false,"NCT07871942","Therapeutic Ultrasound for Muscle Recovery After Muscle Fatigue Exercise","Effects of Therapeutic Ultrasound on Muscle Recovery After Muscle Fatigue Exercise: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Men and women aged 18 to 45 years.\n* Literate participants.\n* Normotensive participants, defined as systolic blood pressure \\\u003C120 mmHg and diastolic blood pressure \\\u003C80 mmHg.\n* Participants in good physical and mental health.\n\nExclusion Criteria:\n\n* Obesity, defined as body mass index (BMI) \\>30 kg\u002Fm².\n* Smoking.\n* Continuous medication use.\n* Previous diagnosis of rheumatological, metabolic, cardiovascular, neurological, oncological, immunological, or hematological diseases.\n* Psychiatric and\u002For cognitive disorders.\n* Musculoskeletal dysfunction or pain on the day of assessment.\n* Consumption of alcoholic or caffeinated beverages or foods on the day of assessment.\n* Performance of intense physical activity within 48 hours before the assessments.",true,"ALL","18 Years","45 Years",{"count":21,"type":22},30,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized, parallel, placebo-controlled, double-blind clinical trial will evaluate the effects of low-intensity therapeutic ultrasound on muscle recovery after a fatiguing handgrip exercise protocol in healthy adults. Eighty volunteers aged 18 to 45 years will be included and assigned to an intervention group or a placebo group.\n\nParticipants will perform a handgrip exercise protocol designed to induce muscle fatigue. The intervention group will receive pulsed low-intensity therapeutic ultrasound applied to the wrist flexor and extensor muscles, while the placebo group will undergo the same procedures with the ultrasound intensity set to zero.\n\nThe main outcome will be pain. Additional outcomes will include muscle strength, perceived exertion, function, range of motion, inflammatory and muscle damage markers, and oxidative stress parameters. Pain will also be assessed 24, 48, and 72 hours after the exercise protocol.",[28,29],"Muscle Fatigue (C23.888.592.612.612)","Delayed Onset Muscle Soreness (DOMS)",[31,32,33,34],"Ultrasonic Therapy","Myalgia","Post-Exercise Recovery Techniques","Inflammation","NOT_YET_RECRUITING","2026-10-06",{"date":38,"type":39},"2026-10-13","ACTUAL",{"date":41,"type":22},"2026-11-01",{"date":43,"type":22},"2028-06-30",{"name":45,"class":46},"Universidade Federal de Santa Maria","OTHER",""]