[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidade Federal de Sergipe\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100648126","phase-4-time-to-loss-of-consciousness-with-remimazolam-versus-propofol-for-anesthetic-induction-in-laparoscopic-cholecystectomy-100648126",false,"NCT07717684","Time to Loss of Consciousness With Remimazolam Versus Propofol for Anesthetic Induction in Laparoscopic Cholecystectomy","Time to Loss of Consciousness With Remimazolam Versus Propofol During Anesthetic Induction for Laparoscopic Cholecystectomy: A Single-Center Randomized Controlled Trial","REMIPROP-LOC","Inclusion Criteria:\n\n* Patients aged 18 years or older.\n* American Society of Anesthesiologists (ASA) physical status I or II.\n* Scheduled to undergo elective laparoscopic cholecystectomy under Total Intravenous Anesthesia (TIVA).\n\nExclusion Criteria:\n\n* Patients younger than 18 years or older than 50 years\n* American Society of Anesthesiologists (ASA) physical status III to V\n* Body Mass Index (BMI) \\\u003C 17.5 kg\u002Fm² or \\> 30 kg\u002Fm²\n* Hemodynamically unstable patients\n* Altered or impaired renal or hepatic function\n* Neuromuscular disorders\n* History of alcohol or drug dependence\n* History of allergy or hypersensitivity to any of the anesthetic medications utilized in the protocol","ALL","18 Years","49 Years",{"count":21,"type":22},66,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","The goal of this clinical trial is to compare two medicines used to induce general anesthesia in adults undergoing elective laparoscopic cholecystectomy. The study aims to determine whether remimazolam leads to a different time to loss of consciousness than propofol.\n\nThe main question it aims to answer is: Does remimazolam change the time to loss of consciousness compared with propofol during anesthesia induction?\n\nResearchers will compare remimazolam with propofol to evaluate the time required for participants to lose consciousness. The study will also compare blood pressure, heart rate, and other safety outcomes during anesthesia induction.\n\nParticipants will:\n\n* Be randomly assigned to receive either remimazolam or propofol for anesthesia induction.\n* Receive standard monitoring and anesthesia care throughout surgery.\n* Have their time to loss of consciousness, vital signs, and any adverse events recorded during the induction period.",[28,29],"Intravenous Anesthesia","Cholelithiasis",[31,32,33,28],"Propofol","Remimazolam","General Anesthesia","RECRUITING","2026-08-02",{"date":37,"type":38},"2026-08-04","ACTUAL",{"date":40,"type":22},"2026-08",{"date":42,"type":22},"2027-06",{"name":44,"class":45},"Universidade Federal de Sergipe","OTHER",""]