[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Guarulhos\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":116},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,40,63,87],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100646510","short-implants-in-unitary-implant-supported-rehabilitations-in-the-posterior-maxilla-and-mandible-5-years-of-follow-up-100646510",false,"NCT07688408","Short Implants in Unitary Implant-supported Rehabilitations in the Posterior Maxilla and Mandible: 5 Years of Follow-up","Short Implants (7 and 8 mm) in Unitary Implant-supported Rehabilitations in the Posterior Sector of the Maxilla and Mandible: 5 Years of Follow-up","Inclusion Criteria:\n\n* Individuals (\\> 21 years old), of both sexes, specifically rehabilitated with morse connection implants (Implacil De Bortoli, São Paulo, SP, Brazil) in the posterior region of the jaws for single-sided unsupported restorations, will be included in this study. Individuals will also need to have at least initial radiographic controls (immediately after implant placement) and 12 and 60 months of follow-up after implant placement. Individuals will be included in the population sample, with the following criteria observed: location, implant installation region, implant diameter, and adaptation.\n\nExclusion Criteria:\n\n* Immediate implants will be excluded, individuals with clinical records who, throughout the study, do not have radiographs for evaluation and\u002For radiographs of poor quality that make radiographic measurements impossible; medical records with insufficient data, filled out inappropriately or that indicate doubt about the details of the procedure performed.",true,"ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","Implant-supported rehabilitation of regions with severe bone resorption is a challenge for implant dentists. Structures such as the maxillary sinus and the inferior alveolar canal often make it impossible to use implants of lengths considered standard in the literature. The use of short 7 and 8 mm implants with new macrogeometries and surface treatments, in addition to the application of Morse taper prosthetic connections, has shown results that increasingly encourage their use. However, the longevity of these rehabilitations needs to be constantly evaluated. In this work, unitary implant-supported rehabilitations in the posterior jaws, supported by short (7 and 8 mm) tapered Morse connection implants, will be followed for a period of 5 years. A total of 100 subjects rehabilitated with tapered Morse connection implants, with diameters between 3.5 and 4.5 mm, will be evaluated. Peri-implant bone remodeling, implant stability measured through ISQ and clinical parameters will be evaluated per implant and over the evaluation time. Periapical radiographs will be obtained and digitized, analyzed by software and compared with the initial data. The data obtained will be analyzed, allowing longitudinal evaluations and the success rate of implant restorations supported by short implants.",[25,26],"Periodontitis","Periodontal Disease","NOT_YET_RECRUITING","2026-07-06",{"date":30,"type":31},"2026-07-08","ACTUAL",{"date":33,"type":21},"2026-06-28",{"date":35,"type":21},"2027-02-28",{"name":37,"class":38},"University of Guarulhos","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":49,"conditions":50,"keywords":52,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":4},"100646761","longitudinal-evaluation-of-several-modalities-of-treatment-of-peri-implantitis-5-to-23-years-follow-up-100646761","NCT07684001","Longitudinal Evaluation of Several Modalities of Treatment of Peri-implantitis: 5 to 23 Years Follow-up","longitudinal","Inclusion Criteria:The sample included 300 systemically healthy individuals, over 18 years of age, who received some type of treatment (surgical or non-surgical) for peri-implantitis, associated or not with systemic antibiotic therapy. Subjects cannot have undergone periodontal treatment for at least 6 months prior to the start of the study; agree to participate in the study and agree to sign the ICF.\n\n\\-\n\nExclusion Criteria:Individuals who have lost the treated implants after some peri-implant therapy and those who do not accept to sign the ICF will be excluded.\n\n\\-",{"count":48,"type":21},300,"To evaluate the peri-implant conditions of patients undergoing different surgical and non-surgical techniques, associated or not with regenerative therapies after long periods of time (between 5 and 23 years)\n\n3\\. MATERIAL AND METHODS\n\n3.1. Experimental design This retrospective study will evaluate the peri-implant conditions of patients with peri-implantitis treated at the UnG Clinic using various types of treatments. To this end, participants will be selected from the UnG graduate clinic who received some type of treatment (surgical or non-surgical) until 2021. Participants selected for the study must sign the Informed Consent Form (ICF) after verbal and written explanation of the project. Subjects will receive oral hygiene instruction and professional prophylaxis prior to clinical examinations.\n\n3.2. Sample selection This clinical study will be submitted for approval by the Ethics Committee of the University of Guarulhos (CEP-UnG). Subjects (minimum of 50 and maximum of 300) will be recruited and evaluated at the Implantology clinic of Guarulhos University. This sample was obtained based on the power test so that the study presented a power of around 80%, and NCI and bone loss were considered primary variables.\n\n3.3. Inclusion criteria The sample included 300 systemically healthy individuals, over 18 years of age, who received some type of treatment (surgical or non-surgical) for peri-implantitis, associated or not with systemic antibiotic therapy.\n\n3.4. Sample exclusion criteria Individuals who have lost the implants after some peri-implant therapy;' have undergone periodontal treatment for at least 6 months prior to the start of the study.\n\nClinical examinations A single, trained and calibrated examiner will perform all clinical examinations. The examiner will be trained and calibrated before and during the study in order to achieve maximum reproducibility in measurements. The methodology to be used for intra-examiner calibration will be the one recommended by Araujo et al. 2003, in which the standard error of measurement for continuous periodontal clinical parameters is evaluated. For the other clinical variables, the mean level of agreement between the examiners will be determined and considered satisfactory when the value is greater than 90% (Kappa test).\n\nClinical measures\n\nThe following parameters will be recorded at six sites per implant using a periodontal probe North Carolina:\n\n1. Plate index: 0 = absence of plaque; 1 = separate patches of plaque at the cervical margin; 2 = a thin, continuous band of plaque \\[up to 1 mm\\] at the cervical margin of the tooth; 3 = strip of plaque greater than 1 mm, but covering less than 1\u002F3 of the tooth crown; 4 = plaque that covers at least 1\u002F3 but less than 2\u002F3 of the tooth's crown; 5 = plate covering 2\u002F3 or more of the tooth's crown).\n2. Gingival index : 0 = absence of inflammation; 1 = mild inflammation change in color and little change in texture; 2 = moderate inflammation - tempered glasses, redness, edema and hypertrophy; 3 = severe inflammation - marked redness and hyperplasia.\n3. Bleeding on probing: 0 = absence; 1 = presence.\n4. Suppuration: 0 = absence; 1 = presence.\n5. Probing depth: distance (mm) from the peri-implant mucosal margin to the most apical portion of the peri-implant pocket.\n6. Relative attachment level: distance (mm) from the implant shoulder to the most apical portion of the peri-implant pocket.\n7. Keratinized tissue height : vertical distance (mm) measured from the mucogingival line to the peri-implant margin in the center of the buccal face of the implant.\n8. Keratinized tissue thickness 1: measured in the center of the buccal surface of the ridge, at the midpoint between the mucogingival line and the top of the ridge.\n9. Mesial and distal keratinized tissue thickness 2: measured over the ridge (mesial and distal of the implant) when the crown can be removed.\n10. Evaluation of the biotype of peri-implant tissue: thin or thick, according to the visualization of the periodontal probe through the peri-implant tissue.\n\nScrew-retained implant crowns will be removed to observe clinical records, while cemented crowns will not be removed.\n\nRadiographic measurements As a way of evaluating the stability of bone tissue, the interproximal level of the bone crest will be measured by means of periapical radiographs. After the radiographic takes, the radiographs will be scanned and the distance in millimeters from the interproximal bone crest to the base of the implant will be evaluated.",[26,51],"Microbiology",[53,54],"peri-implantitis","periodontal diseases","2026-07-03",{"date":57,"type":31},"2026-07-07",{"date":59,"type":21},"2026-06-29",{"date":61,"type":21},"2027-03-29",{"name":37,"class":38},{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":4,"eligibilityCriteria":68,"healthyVolunteers":16,"sex":17,"minAge":69,"maxAge":4,"enrollmentInfo":70,"targetDuration":71,"studyType":22,"phases":4,"briefSummary":72,"conditions":73,"keywords":76,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":81,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":4},"100624152","3d-printed-customized-bone-graft-for-alveolar-regeneration-longitudinal-cohort-evaluation-100624152","NCT07405918","3D Printed Customized Bone Graft for Alveolar Regeneration: Longitudinal Cohort Evaluation","Inclusion Criteria:\n\n* Systemically healthy individuals\n* over 18 years of age\n* Subjects that received regenerative surgical treatment by customized 3D printed blocks.\n* Subjects must agree to participate in the study and agree to sign the Informed Consent.\n\nExclusion Criteria:\n\n* Subjects with ilness that avoid their presence to the clinical evaluation\n* ISubjects who have lost the customized blocks\n* Subjects who do not agree to participate in the study will be excluded.","15 Years",{"count":20,"type":21},"6 Years","This study will evaluate the behavior of the implant-supported restorations (prosthesis) placed into the areas grafted with the 3D printed customized bone (personalized graft produced to fit a specific bone defect), as well as the volume contraction of the printed bone.",[74,75],"Periodontal Diseases","Periodontal Bone Loss",[77,78,79,80],"Personalized bone graft","3D printed customized bone block","Guided Bone Regeneration","Personalized Medicine",{"date":57,"type":31},{"date":83,"type":21},"2026-07-01",{"date":85,"type":21},"2026-12-01",{"name":37,"class":38},{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":91,"acronym":4,"eligibilityCriteria":92,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":96,"conditions":97,"keywords":102,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":39},"100604653","digital-quantification-of-dental-plaque-based-on-intraoral-scanner-images-100604653","NCT07152314","Digital Quantification of Dental Plaque Based on Intraoral Scanner Images","Inclusion Criteria:\n\n* Presence of at least 20 natural teeth\n* Visible plaque index \\> 20% at initial assessment\n* Age between 18 and 65 years\n* Both sexes eligible\n\nExclusion Criteria:\n\n* Use of fixed orthodontic appliances\n* Presence of extensive restorations or fixed dentures on the anterior teeth\n* Systemic conditions that interfere with the formation of dental biofilm\n* Use of medications that alter salivary flow","65 Years",{"count":95,"type":21},20,"This diagnostic validation study aims to develop and validate a digital method for dental biofilm quantification using three-dimensional images obtained by an intraoral scanner. Twenty participants will undergo intraoral scanning at three time points: before and after plaque disclosure, and after supervised toothbrushing. The digital method's accuracy will be compared with traditional clinical assessment methods (Turesky Plaque Index).",[98,99,100,101,26],"Dental Plaque (Diagnosis)","Dental Plaque Imaging Methods","Dental Plaque","Gingivitis",[103,104,105,106,107],"Dental Biofilm","Intraoral Scanner","Preventive Dentistry","Plaque quantification","Digital Diagnosis","2025-08-28",{"date":110,"type":31},"2025-09-03",{"date":112,"type":21},"2025-09",{"date":114,"type":21},"2026-08",{"name":37,"class":38},""]