[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"University of Vigo\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":268},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,46,75,101,131,156,189,211,242],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100652778","characterization-and-validation-of-the-short-physical-performance-battery-in-individuals-diagnosed-with-parkinsons-disease-100652778",false,"NCT07780461","Characterization and Validation of the Short Physical Performance Battery in Individuals Diagnosed With Parkinson's Disease","Observational Study for the Functional Characterization of the Population Diagnosed With Parkinson's Disease in Galicia, and Validation of the Short Physical Performance Battery in Individuals Diagnosed With Parkinson's Disease","PDSPPB","Inclusion Criteria:\n\n* Clinical diagnosis of Parkinson's disease confirmed by a neurologist.\n* Provision of written informed consent by the participant or, when applicable, by a legally authorized representative.\n\nExclusion Criteria:\n\n* Inability to complete the study assessment procedures.","ALL","18 Years",{"count":20,"type":21},350,"ESTIMATED","1 Week","OBSERVATIONAL","Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with motor and non-motor impairments that affect physical function, mobility, balance, and quality of life. Although Galicia is one of the Spanish regions with a high prevalence of PD, comprehensive information regarding the functional characteristics of this population remains limited.\n\nThis observational cross-sectional study aims to characterize the sociodemographic, clinical, cognitive, behavioral, and functional profile of individuals with Parkinson's disease in Galicia and to evaluate the validity and reliability of the Short Physical Performance Battery (SPPB) in this population. The findings will provide updated information on the functional status of people with PD in Galicia and support the use of the SPPB as a practical tool for the assessment of physical performance in clinical and research settings.",[26],"PARKINSON DISEASE (Disorder)",[28,29,30,31,32],"Parkinson´s Disease","Physical Function","Short Physical Performance Battery (SPPB)","Functional Assessment","Psychometric Validation","RECRUITING","2026-08-18",{"date":36,"type":37},"2026-08-21","ACTUAL",{"date":39,"type":37},"2026-08-01",{"date":41,"type":21},"2026-12-25",{"name":43,"class":44},"University of Vigo","OTHER",2,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},"100649888","immersive-virtual-reality-and-exercise-programs-in-multiple-sclerosis-exerviem-iii-100649888","NCT07738120","Immersive Virtual Reality and Exercise Programs in Multiple Sclerosis: ExeRVIEM III","Effects of a Physiotherapy Program With High-Intensity Exercise and Immersive Virtual Reality in Multiple Sclerosis: Randomized Controlled Trial","ExeRVIEM III","Inclusion Criteria:\n\n* ≥18 years of age.\n* Confirmed diagnosis of MS.\n* Stable disease with no relapse in the previous 6 weeks.\n* Patients who will be take follow up by a neurologist at the referral hospital and will be members of the patient association.\n* Ability to perform moderate exercise.\n* Capacity to provide informed consent.\n\nExclusion Criteria:\n\n* Comorbidities that hinder the development of the VR program\n* Visual or vestibular impairment that would contraindicate VR use.\n* Recent changes in disease modifying therapy.",{"count":55,"type":21},30,"INTERVENTIONAL",[58],"NA","TITLE: Immersive Virtual Reality and Exercise Programs in Multiple Sclerosis: ExeRVIEM III. INTRODUCTION: Multiple sclerosis (MS) is a chronic neuroimmunological and degenerative disease characterized by demyelination within the central nervous system. Its clinical course involves motor impairment, sensory disturbances, cognitive dysfunction, and a progressive decline in functional independence. MS is one of the leading causes of non-traumatic disability in young adults. This highlights the considerable impact of the disease, both in terms of healthcare burden and healthcare expenditure. Within this context, therapeutic exercise has evolved from being considered potentially harmful to being recognized as a safe and effective intervention capable of improving gait, balance, cardiorespiratory fitness, fatigue, and quality of life in people with MS. A model has been proposed for prescribing and progressing exercise at different stages of MS: passive range-of-motion exercises designed for patients with the most severe symptoms, a second stage incorporating active muscle-strengthening exercises, and finally, integrated exercise programs that incorporate strength, endurance, balance, and coordination training. Evidence from systematic reviews and meta-analyses shows that structured exercise (including high-intensity protocols when performed under supervision) is safe and can improve functional outcomes. Our ExeRVIEM III project (Physiotherapy program with High-Intensity Exercise Program and Immersive Virtual Reality in Multiple Sclerosis) represents a novel strategy to facilitate rehabilitation exercise programs using head-mounted virtual reality displays. HYPOTHESIS: The ExeRVIEM III project, based on training physical function in people with MS, is feasible and safe, and could have a potential clinical impact in the motor and cognitive domains, as well as applicability in community settings, such as patient associations. GENERAL OBJECTIVES: 1.1 To design and implement an ExeRVIEM III exercise program\u002Fprotocol for people with MS. 1.2 To evaluate the safety of the high-intensity virtual reality exercise program. SPECIFIC OBJECTIVES: 2.1 To analyze the possible changes in disability, functional variables, cognitive domains and biomarkers in the short and medium term in people who attend a patient association and carry out the ExeRVIEM III exercise program for people with MS. METHODOLOGY: A randomized controlled trial, double-arm (experimental and control group) study will be conducted at a patient association (Santiago de Compostela, Spain). The intervention will consist of an 6-month supervised virtual rehabilitation program, with two weekly sessions on alternate days, in addition to the standard rehabilitation prescribed by the patient association clinical team (physiotherapy, occupational therapy, and cognitive training sessions). An inmersive virtual reality (IVR) body combat exercise videogame will be used, administered via a virtual reality headset. In accordance with clinical guidelines for IVR, sessions will be intentionally brief (10 minutes) to minimize cybersickness and excessive fatigue. Assessments will be conducted at baseline (week 0) and immediately after the intervention (week 24). Demographic and clinical data will also be collected, including sex, age, comorbidities, disease duration, MS subtype, and pharmacological treatment. Assessments will be conducted at the patient association and in the Neurology Department of the referral hospital. Feasibility, safety, strength parameters, dual-task performance and fatigue levels assessments will be performed at the patient association by physiotherapists, while the remaining assessments will be completed at the hospital by a neurologist specializing in MS. The content of the assessments will be: Patient characteristics that will include data on age, sex, years since diagnosis, MS subtype, and pharmacological treatment. Feasibility: Number of virtual sessions attended by each participant (adherence rate via registration sheet). Rate Perceived Effort using the modified Borg scale, which measures the level of perceived exertion on a scale of 0 to 10 from no effort to maximum effort. Safety: adverse events using the Simulator Sickness Questionnaire (SSQ).Strength parameters using Five times sit to stand test (FTSST) and handgrip test. Functional mobility will be assessed using Timed and Go test (TUG) and with dual task performance using TUG-cog. Level of fatigue using the Fatigue Severity Scale (FSS). Level of disability: using the Expanded Disability Status Scale (EDSS).Gait will be evaluated using the 25Foot Walk Test (25FWT). Manual dexterity will be assessed using 9-Hole Peg Test (9HPT). Cognitive domains evaluated by the Symbol Digit Modalities Test (SDMT)Axonal injury biomarker evaluated by Neurofilament light chain (sNfL) concentrations.",[61,62,63,64,65],"Multiple Sclerosis","Exercise","Physical Therapy","Virtual Reality Exposure Therapy","Rehabilitation Exercise","2026-07-28",{"date":68,"type":37},"2026-07-31",{"date":70,"type":37},"2025-10-06",{"date":72,"type":21},"2026-08-07",{"name":43,"class":44},1,{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":81,"minAge":18,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":56,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":74},"100642415","effect-of-exercise-on-the-width-and-stiffness-of-the-linea-alba-in-postpartum-women-with-diastasis-100642415","NCT07639125","Effect of Exercise on the Width and Stiffness of the Linea Alba in Postpartum Women With Diastasis","Inclusion Criteria:\n\n* Adult woman (\\> 18 years old)\n* Women who agreed to participate and provided written informed consent\n* Women between 6 and 12 weeks postpartum at the time of recruitment.\n\nExclusion Criteria:\n\n* History of previous abdominal surgery ( except cesarean section)\n* Presence of abdominal or umbilical hernias\n* Current pregnancy\n* Neuromuscular or systemic conditions affectinf the abdominal wall\n* Active infections\n* Any condition that could intervere with the correct execution of the measurement protocol.\n* Incomplete records or measurements that do not meet elastography quality criteria will be excluded.","FEMALE",{"count":55,"type":21},[58],"his study aims to evaluate the effect of an exercise program in postpartum women with diastasis recti, defined as an inter-rectus distance greater than 2 cm at any of three ultrasound measurement points . Participants will be divided into two groups: an intervention group that will follow a 6-week exercise program and a control group that will receive usual care.\n\nUltrasound assessment of the linea alba will be performed before the intervention and after 6 weeks. The main outcomes will be inter-rectus distance and the stiffness of the linea alba measured using shear wave elastography, along with obstetric and personal clinical variables. Participants will be recruited from primary care centers in the Community of Madrid through midwives during postpartum consultations.",[86],"Diastasis Recti And Weakness Of The Linea Alba",[88,89,90,91],"diastasis recti","Postpartum woman","exercise therapy","ultrasound","NOT_YET_RECRUITING","2026-06-05",{"date":95,"type":37},"2026-06-10",{"date":97,"type":21},"2026-06",{"date":99,"type":21},"2026-09-30",{"name":43,"class":44},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":81,"minAge":18,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":56,"phases":110,"briefSummary":111,"conditions":112,"keywords":116,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":123,"lastUpdatePostDateStruct":124,"startDateStruct":126,"completionDateStruct":128,"leadSponsor":130,"locationsCount":74},"100628350","plyometric-strength-endurance-exercise-in-breast-cancer-100628350","NCT07460492","Plyometric Strength-Endurance Exercise in Breast Cancer","Therapeutic Plyometric-Based Strength-Endurance Exercise Program for Breast Cancer Patients and Survivors to Improve Quality of Life and Physical and Mental Function","Inclusion Criteria:\n\n* Women aged 18 years or older.\n* Prior diagnosis of breast cancer.\n* History of mastectomy, including unilateral procedures, total breast surgery, or breast-conserving surgery.\n* Completion of postoperative chemotherapy or radiotherapy, when indicated.\n* Absence of contraindications for physiotherapy or therapeutic exercise.\n* Willingness to voluntarily participate in the study.\n* Ability to understand and sign the informed consent form.\n* Availability to participate in the training program for the entire intervention period (approximately 12 weeks).\n\nExclusion Criteria\n\n* Participants will be excluded if any of the following conditions are present:\n* Active metastasis to other organs or tissues (e.g., liver, kidney, lung, brain) or stage IV cancer that prevents safe participation in the therapeutic exercise program.\n* Current diagnosis of cardiovascular, respiratory, neuromuscular, or musculoskeletal diseases that contraindicate physical exercise or impair safe completion of the program.\n* Major surgery within the previous 6 months without medical clearance to resume physical activity.\n* Cognitive impairment or mental health conditions that limit comprehension of instructions or safe engagement in the intervention.\n* Current pregnancy.\n* Lack of medical clearance for moderate-to-vigorous physical activity (as indicated by a medical certificate specifying the duration of the restriction and the conditions under which exercise may be resumed).",{"count":109,"type":21},51,[58],"This study aims to compare an adapted plyometric strength-endurance exercise program with conventional strength training in women who are breast cancer survivors or currently undergoing treatment and who participate in provincial support associations. The goal is to determine whether a targeted plyometric intervention can provide additional benefits in physical and mental health outcomes.\n\nUsing a cluster-randomized clinical trial design, the study will assess indicators such as functional capacity, muscle strength, fatigue levels, symptoms related to lymphedema, and overall quality of life. The findings are expected to contribute to a better understanding of how structured exercise programs can support recovery, physical function, and well-being in women affected by breast cancer.",[113,114,115],"Neoplams","Patients","Cancer Survivors",[117,118,119,120,121,122],"Randomized Controlled Trial","Cluster Analysis","quality of life","physical functional performance","functional status","mental health","2026-03-10",{"date":125,"type":37},"2026-03-13",{"date":127,"type":21},"2026-04-20",{"date":129,"type":21},"2027-12-31",{"name":43,"class":44},{"id":132,"slug":133,"hasResults":11,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":138,"sex":17,"minAge":139,"maxAge":140,"enrollmentInfo":141,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":143,"conditions":144,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":74},"100625190","isometric-strength-and-joint-mobility-profile-in-elite-artistic-swimmers-across-competitive-categories-100625190","NCT07419412","Isometric Strength and Joint Mobility Profile in Elite Artistic Swimmers Across Competitive Categories","General Assessment of Strength and Mobility in Artistic Swimmers of the Spanish Swimming Federation","Inclusion Criteria:\n\n* Elite artistic swimmers selected for the Spanish National Artistic Swimming Team (Infant, Junior, or Senior categories).\n* Age consistent with the competitive category: Infant 14-16 years, Junior 16-18 years, Senior ≥18 years.\n* Attendance at the national team training camp where the assessments are performed.\n* Voluntary participation with written informed consent (and assent\u002Fparental or legal guardian consent for minors).\n\nExclusion Criteria:\n\n* Acute musculoskeletal or joint injury affecting the tested regions (shoulder, hip, elbow, knee) at the time of assessment.\n* Chronic, previous, or any other condition that may limit participation or bias the measurements.\n* Inability to attend the assessment session(s) during the training camp.",true,"14 Years","50 Years",{"count":142,"type":21},45,"This cross-sectional observational study aims to establish reference values for joint mobility and isometric muscle strength in elite artistic swimmers across different competitive categories. The study will analyze inter-limb asymmetries and agonist-antagonist strength ratios in upper and lower limbs. Additionally, relationships between isometric strength, countermovement jump performance, and handgrip strength will be explored to assess their utility as functional performance indicators. Participants will be assessed during national team training camps using standardized, validated measurement protocols. The findings are expected to contribute to the identification of sport-specific functional profiles and potential injury risk factors in artistic swimming.",[145,146,147],"Swimming","Stretch","Assessment, Self","2026-02-19",{"date":150,"type":37},"2026-02-23",{"date":152,"type":37},"2026-01-10",{"date":154,"type":21},"2026-03-30",{"name":43,"class":44},{"id":157,"slug":158,"hasResults":11,"nctId":159,"briefTitle":160,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":11,"sex":81,"minAge":162,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":56,"phases":166,"briefSummary":167,"conditions":168,"keywords":173,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":74},"100589273","effects-of-two-strength-exercise-programs-on-upper-limb-functionality-in-breast-cancer-100589273","NCT06952270","Effects of Two Strength Exercise Programs on Upper Limb Functionality in Breast Cancer","Inclusion Criteria:\n\n* Pathological diagnosis of breast cancer.\n* Patients who have undergone a mastectomy, including unilateral, total breast, or breast-conserving surgery.\n* Postoperative chemotherapy or radiotherapy as required.\n* No other malignant tumors in the last 5 years.\n* Absence of contraindications related to physiotherapy or physical exercise.\n* Willingness to participate in the study and sign the informed consent form.\n\nExclusion Criteria:\n\n* Metastasis to other organs and tissues (liver, kidney, lung, brain, etc.) that prevent participation in the exercise program.\n* Underlying heart disease, cerebrovascular disease, or mental illness that impairs proper execution of the exercise program.\n* Pre-existing shoulder pathology before surgery.\n* Inability to understand the plyometric exercise program.","25 Years","75 Years",{"count":165,"type":21},24,[58],"The goal of this experimental study is to evaluate the effect of a therapeutic exercise program based on upper limb plyometric exercises in breast cancer patients and breast cancer survivors to determine changes in upper limb functionality.\n\nThe main question it aims to answer is: Does upper limb plyometric strength exercise improve upper limb dysfunctions in breast cancer patients and survivors? The researchers will compare the effects of plyometric exercise with the effects of strength training exercise to determine whether plyometric exercise improves shoulder dysfunctions in breast cancer patients and survivors.\n\nParticipants from the Pontevedra group will undergo the intervention using plyometric exercise (Experimental Group), while those from the Vigo group will perform strength training exercise (Control Group). They will complete two sessions per week for six weeks. Outcome variables related to upper limb functionality will be assessed at baseline and after the intervention.",[169,170,171,172],"Breast Cancer Survivor","Breast Cancer","Breast Cancer Patients","Breast Cancer - Female",[174,175,176,177,178,179,180],"breast cancer","plyometric exercise","upper limb","strength training","exercise","Recovery of Function","clinical trial","2025-04-26",{"date":183,"type":37},"2025-04-30",{"date":185,"type":21},"2025-05-02",{"date":187,"type":21},"2025-07",{"name":43,"class":44},{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":138,"sex":17,"minAge":139,"maxAge":18,"enrollmentInfo":196,"targetDuration":4,"studyType":56,"phases":198,"briefSummary":199,"conditions":200,"keywords":4,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":4},"100588346","multidirectional-isometric-assessment-of-the-hip-100588346","NCT06940206","Multidirectional Isometric Assessment of the Hip","Multidirectional Isometric Assessment of the Hip in Young Swimmers","Inclusion Criteria:\n\n* Aged between 14 and 18 years.\n* Swimmers who train at least 15 hours weekly.\n* Swimmers who have participated in the national championship this season.\n\nExclusion Criteria:\n\n* Swimmers with any current hip or lower limb pathology.\n* Swimmers who have required hip surgery.\n* Swimmers who, for any other reason, are unable to complete an isometric maximal strength test.\n* No ability to perform the Multidirectional Isometric Assessment of the Hip without compensatory movements.\n* Refusal to sign informed consent (or legal guardian's consent for minors).",{"count":197,"type":21},55,[58],"With the exception of the shoulder, the hip is among the most frequently injured areas in swimmers. Despite this, hip injuries are often overlooked in training and prevention programmes. Such neglect can cause significant damage to muscles, particularly the adductors, and the joint itself, potentially requiring arthroscopic surgery or even leading to secondary injuries in related structures such as the knee. Furthermore, hip strength and range of motion directly affect swimmers' underwater kicking speed. Although hip assessments are common in other sports, like football, for injury prevention and performance analysis-both dynamically and isometrically-isometric testing is particularly recommended due to its higher reproducibility.\n\nTherefore, this study aims to validate a multidirectional isometric hip test in swimmers and examine agonist-antagonist muscle ratios in young advanced swimmers.\n\nA comparative analysis will be conducted on 30 elite swimmers. This will include a descriptive analysis of the group and comparative analyses between breaststroke\u002Fnon-breaststroke swimmers and between genders. Maximum isometric contractions of both lower limbs will be measured using a Chronojump force sensor (Boscosystem, Barcelona, Spain).\n\nAthletes will stand on a step positioned centrally within a rack or cage, either laterally or frontally depending on the movement assessed (ABD-ADD or flexion-extension, respectively). They will grip the appropriate supports with their hands and perform three maximal efforts of each movement lasting 3 seconds, without compensatory actions (any attempt with compensations will be discounted). There will be a 20-second rest between attempts. All three attempts will be recorded.\n\nTo assess measurement reliability, tests will be repeated after 48 hours for subsequent comparison.",[201,202,147],"Sports Physical Therapy","Hip","2025-04-23",{"date":205,"type":37},"2025-04-27",{"date":207,"type":21},"2025-04-28",{"date":209,"type":21},"2025-06-30",{"name":43,"class":44},{"id":212,"slug":213,"hasResults":11,"nctId":214,"briefTitle":215,"officialTitle":216,"acronym":217,"eligibilityCriteria":218,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":219,"targetDuration":4,"studyType":56,"phases":221,"briefSummary":222,"conditions":223,"keywords":226,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":235,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":241,"locationsCount":5},"100320848","treatment-of-hypertension-during-sleep-100320848","NCT03457168","Treatment of Hypertension During Sleep","A Prospective, Randomized, Open-label Clinical Trial on the Effects of Intensive Versus Conventional Control of Ambulatory-determined Asleep Systolic Blood Pressure Mean on Cardiovascular, Metabolic, and Renal Disease Risks","THADEUS","Inclusion Criteria:\n\n1. Men and women aged ≥18 years.\n2. All participants must: (i) have at randomization sleep-time hypertension according to the current ESH\u002FESC guidelines, i.e., asleep SBP mean ≥120 mmHg;1 (ii) adhere to a routine of daytime activity and nighttime sleep; and (iii) provide their written informed consent to participate into the study.\n\nExclusion Criteria:\n\n1. Pregnancy.\n2. History of drug\u002Falcohol abuse within the last two years.\n3. Night\u002Fshift-work employment.\n4. Previous history of a systemic autoimmune disease or AIDS.\n5. Evidence of a secondary form of hypertension, including coarctation of the aorta, hyperaldosteronism, renal artery stenosis, or pheochromocytoma\n6. CVD disorders (unstable angina pectoris, heart failure, life-threatening arrhythmia, atrial fibrillation, kidney failure, and grade III-IV retinopathy). Previous CVD events will not be exclusionary if full physical and work activities are maintained.\n7. Any surgical or medical condition which might alter the absorption, distribution, metabolism, or excretion of any drug, or, at the discretion of the investigator, might place the subject at higher risk from his\u002Fher participation in the study, or are likely to prevent the subject from complying with the requirements of the study or completing the trial period.\n8. History of malignancy including leukemia and lymphoma (but not basal cell skin cancer), or any other severe, life-threatening disease within the past five years.\n9. Inability to communicate and comply with all study requirements.\n10. Intolerance to ABPM.",{"count":220,"type":21},5320,[58],"On the basis of new evidence on the relationship between achieved office blood pressure (BP) measurements (OBPM) and the risk of cardiovascular disease (CVD) morbidity and mortality documented in the SPRINT trial, the recent 2017 guidelines of the American College of Cardiology (ACC) and the American Heart Association (AHA) have established lower values of 130\u002F80 mmHg for clinic systolic BP (SBP)\u002Fdiastolic BP (DBP) as new diagnostic thresholds for hypertension and therapeutic targets for treatment of all individuals aged ≥18 years regardless of age, sex, or concomitant complications including presence of diabetes, chronic kidney disease (CKD), or history of past CVD event. According to these guidelines, the new proposed ambulatory BP measurment (ABPM) thresholds for diagnosis of hypertension in adults are 130\u002F80 and 110\u002F65 mmHg for the awake and asleep SBP\u002FDBP means, respectively. However, the ACC\u002FAHA guidelines do not provide any scientific evidence documenting neither the equivalence between these ABPM thresholds and the 130\u002F80 mmHg cut-off values for OBPM nor the potential improved CVD event-free survival time of the proposed more intensive control of ambulatory BP.\n\nResults derived from observational prospective studies consistently document that therapeutic BP targets in hypertensive individuals, i.e., persons at increased CVD risk, should be established in terms of proper control of asleep BP. To date, no prospective randomized study has ever before evaluated which should be the adequate therapeutic ABPM target for most effective reduction of CVD risk. Accordingly, the Tratamiento de Hipertensión Arterial Durante el Sueño study (THADEUS, i.e., Treatment of Hypertension During Sleep) has been designed to prospectively evaluate if \"intensive control\" of asleep SBP mean proposed by the new ACC\u002FAHA guidelines (\\\u003C110 mmHg) in more effective than the so far its \"conventional control\" (\\\u003C120 mmHg) to reduce CVD morbidity and mortality in hypertensive individuals.",[224,225],"Hypertension","Hypertension, Systolic",[227,228,229,230,231,232,233],"Sleep-time hypertension","Ambulatory blood pressure monitoring","Hypertension chronotherapy","Asleep blood pressure","Cardiovascular risk","Type 2 diabetes","Chronic kidney disease","2024-12-03",{"date":236,"type":37},"2024-12-06",{"date":238,"type":37},"2019-02-01",{"date":240,"type":21},"2032-12-31",{"name":43,"class":44},{"id":243,"slug":244,"hasResults":11,"nctId":245,"briefTitle":246,"officialTitle":246,"acronym":4,"eligibilityCriteria":247,"healthyVolunteers":138,"sex":17,"minAge":18,"maxAge":248,"enrollmentInfo":249,"targetDuration":4,"studyType":56,"phases":251,"briefSummary":252,"conditions":253,"keywords":255,"overallStatus":92,"whyStopped":4,"lastUpdateSubmitDate":260,"lastUpdatePostDateStruct":261,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":267,"locationsCount":4},"100563616","effects-of-kinesiotape-or-neuromuscular-taping-on-the-activation-of-the-transversus-abdominis-muscle-a-pilot-study-100563616","NCT06618482","Effects of Kinesiotape or Neuromuscular Taping on the Activation of the Transversus Abdominis Muscle. A Pilot Study","Inclusion Criteria:\n\n* The participants are members of the UVIGO who voluntarily participate in the study with an age between 18 and 35 years.\n* The participants are healthy subjects (men and women) of legal age.\n* All subjects must sign the informed consent prior to the experimentation.\n\nExclusion Criteria:\n\n* \\- Suffering from skin disorders, fragile skin or allergy to adhesive bandages.\n* Elite athletes.\n* Excessive skin hair in the region to apply the bandage.\n* Receive a bandage in the abdominal or lumbar region two weeks prior to the experiment.\n* History of orthopedic\u002Ftraumatic alterations in the lumbopelvic region (deformities, arthrodesis, arthropathy, muscle injuries, fracture or tendinopathy), neurological disorders (central or peripheral), systemic disorders, circulatory disorders (edema, heart failure, thrombosis, renal failure), or surgery in the abdominal-lumbar region in the last 6 months.\n* Perform abdominal or lumbar strength training 48 hours prior to the study.\n* Limitation greater than 50% in the flexion-extension range of motion of the lumbar spine.\n* Consumption of alcoholic beverages or medications 24 hours prior to the experimentation.\n* Pregnancy or having given birth in less than a year.","35 Years",{"count":250,"type":21},12,[58],"The use of adhesive bandages is a widely practiced technique in both clinical and sports settings. There is a great variety of materials used for bandaging, with multiple objectives: limiting movement, correcting joint positions, reducing pain, enhancing sports performance, and reducing the number of injuries.\n\nHowever, current knowledge about their potential effects is still limited, and more studies are needed to determine the most appropriate application parameters.\n\nFor this reason, the objective of the study for which we request your collaboration is to determine to what extent the application of an adhesive bandage (neuromuscular tape) can influence muscle facilitation through fiber recruitment and strength development, to improve performance during exercise.\n\nThe information derived from this research will provide a better understanding of the influence that an adhesive bandage (neuromuscular tape) can have on the neuromuscular system and on strength enhancement.",[254],"Healthy Subjects (HS)",[256,257,258,259],"Kinesiotape","Bandage","Transverse Abdominal","Abdominal Ultrasound","2024-09-25",{"date":262,"type":37},"2024-10-01",{"date":264,"type":21},"2024-09-30",{"date":266,"type":21},"2024-10-16",{"name":43,"class":44},""]