[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Velammal Medical College Hospital and Research Institute\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100653752","magnetic-resonance-imaging-based-risk-stratification-for-defibrillator-implantation-in-heart-failure-patients-requiring-cardiac-resynchronisation-therapy-100653752",false,"NCT07791407","Magnetic Resonance Imaging Based Risk Stratification for Defibrillator Implantation in Heart Failure Patients Requiring Cardiac Resynchronisation Therapy","Magnetic Resonance Imaging Based Risk Stratification for Defibrillator Implantation in Heart Failure Patients Requiring Cardiac Resynchronization Therapy (MADURAI CRT)","MADURAI CRT","Inclusion Criteria:\n\n1. Patients with age ≥18 years\n2. Typical left bundle branch block as defined by Strauss criteria with LVEF ≤35%\n3. Heart failure symptoms despite guideline directed medical therapy (GDMT)\n\nExclusion Criteria:\n\n1. Patients with angiographic evidence of significant coronary artery disease requiring revascularisation. In patients with significant CAD, LVEF will be re-assessed 3 months after revascularisation to decide about CRT\n2. Patients with associated uncorrected congenital or valvular heart disease\n3. Expected life-expectance of \\\u003C12 months due to associated comorbidities\n4. Patients with contrast allergy\n5. Baseline non-LBBB morphology\n6. Renal dysfunction which limits the acquisition of CMR with contrast\n7. Pregnant or lactating women\n8. Patients who are unable to comply with study protocol","ALL","18 Years",{"count":20,"type":21},114,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized study aimed to compare the efficacy of LBBP without defibrillator vs biventricular pacing with defibrillator (BiV-ICD\u002FCRT-D) in patients with LB-NICM and left ventricular ejection fraction (LVEF) ≤35% risk categorized by CMR imaging.",[27],"Non Ischemic Cardiomyopathy",[29],"Cardiac resynchronisation therapy","RECRUITING","2026-08-25",{"date":33,"type":34},"2026-08-27","ACTUAL",{"date":36,"type":21},"2026-08-01",{"date":38,"type":21},"2028-07-15",{"name":40,"class":41},"Velammal Medical College Hospital and Research Institute","OTHER",""]