[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Vivalink\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":54},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,39],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100643953","ai-optimized-single-feature-recognition-model-for-heart-failure-100643953",false,"NCT07667452","AI-Optimized Single-Feature Recognition Model for Heart Failure","Development and Application of a Single-Feature Recognition Model for Heart Failure With Artificial Intelligence-Optimized Algorithms","Inclusion Criteria:\n\n* Age ≥ 18 years old;\n* Body mass index (BMI) \\\u003C 35 kg\u002Fm²;\n* Diagnosed with heart failure: according to \"Chinese Guidelines for Diagnosis and Treatment of Heart Failure in 2024\", \"ESC Guidelines for Diagnosis and Treatment of Acute and Chronic Heart Failure in 2021\", and \"AHA\u002FACC\u002FHFSA Guidelines for Management of Heart Failure in 2022\";\n* NYHA classification II - IV;\n* Able to fully understand the purpose and process of the trial, and willing to sign the informed consent form.\n\nExclusion Criteria:\n\n* Physical disabilities that prevent safe and thorough testing;\n* Open wounds on the chest or the skin is allergic to the patches;\n* Large amount of pericardial effusion, pericardial tamponade, pleural friction rub, pneumothorax, and a large amount of pleural effusion, which may affect data collection;\n* Patients with severe comorbidities or unstable conditions, which may interfere with data collection during the study period;\n* Other situations where the investigator believes the subject is not suitable to participate in this trial, such as those that may increase trial risk, affect the protocol compliance, or impair the subject's ability to complete the trial due to physical or psychological diseases or conditions.","ALL","18 Years",{"count":19,"type":20},50,"ESTIMATED","OBSERVATIONAL","This prospective, single-center and observational study aims to develop and validate the single-feature artificial intelligence algorithm based on data collected via the wearable ECG patches in patients with heart failure (HF).\n\nThe main question: Does the algorithm, using synchronized ECG and accelerometer signals from the ECG patches, achieve accurate detection of heart sounds (S1, S2, and in some patients S3, S4) compared with the Eko CORE 500 digital stethoscope in patients with acute exacerbation of HF? It aims to answer: Participants with confirmed HF (NYHA classification II-IV) will first undergo a 2-minute session of simultaneous ECG patches and digital stethoscope recordings, followed by standard 12-lead ECG, and then the repeated ECG patches and 2-minute heart sound recording session. Data will be used for algorithm training and validation. The primary endpoint is the accuracy of heart sound detection via the Vivalink ECG patches compared with the Eko CORE 500 digital stethoscope.",[24,25],"Cardiac Sound","Heart Failure - NYHA II - IV","RECRUITING","2026-07-18",{"date":29,"type":30},"2026-07-21","ACTUAL",{"date":32,"type":30},"2026-07-16",{"date":34,"type":20},"2027-05-31",{"name":36,"class":37},"Vivalink","INDUSTRY",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":46,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":47,"conditions":48,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":50,"startDateStruct":51,"completionDateStruct":52,"leadSponsor":53,"locationsCount":38},"100643942","single-lead-ecg-conduction-interval-algorithm-100643942","NCT07667465","Single-Lead ECG Conduction Interval Algorithm","Clinical Study on the Optimization Algorithm of Single-Lead Electrocardiogram Conduction Intervals","Inclusion Criteria:\n\n* Age ≥18 years;\n* Body mass index \\\u003C 35 kg\u002Fm²;\n* with stable sinus rhythm;\n* PR interval, QRS duration, or QT interval were stable and at least one was outside the normal range;\n* Able to fully understand the purpose and process of the trial, and willing to sign the informed consent form.\n\nExclusion Criteria:\n\n* Physical disabilities that prevent safe and thorough testing;\n* Open wounds on the chest or skin is allergy to patches;\n* Post-implantation of temporary or permanent cardiac pacemaker, ICD, CRT or CRTD, post-replacement of artificial heart valve, with large amounts of pericardial effusion, pericardial tamponade, pleural friction rub, pneumothorax, large amounts of pleural effusion, etc., which may affect data collection;\n* Patients with severe comorbidities or unstable condition, which may interfere with data collection during the study period;\n* Other situations where the investigator believes the subject is not suitable to participate in this trial, such as those that may increase trial risk, affect the protocol compliance, or impair the subject's ability to complete the trial due to physical or psychological diseases or conditions.",{"count":19,"type":20},"The goal of this prospective, single-center and observational study is to develop and validate an optimization algorithm for single-lead ECG conduction intervals via the wearable ECG patches combined with synchronized heart sound data, and evaluate its agreement with the clinical gold standard (12-lead ECG) in adult patients. The main question: Does the optimized algorithm, based on ECG patches and synchronous heart sound recordings, improve the detection accuracy of PR interval, QRS duration, and QT interval compared with standard 12-lead ECG? It aims to answer: Participants (age ≥18 years, BMI \\\u003C35 kg\u002Fm², stable sinus rhythm with at least one abnormal conduction interval) will first undergo a 2-minute session of simultaneous ECG patches and digital stethoscope recordings, followed by standard 12-lead ECG, and then the repeated ECG patches and 2-minute heart sound recording session. Data will be used for algorithm training and validation. The primary endpoint is the accuracy of the optimized PR interval, QRS duration, and QT interval detection via the Vivalink ECG patches compared with the 12-lead ECG.",[49],"Conduction of Electrocardiogram",{"date":29,"type":30},{"date":32,"type":30},{"date":34,"type":20},{"name":36,"class":37},""]