[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Zoe Global Limited\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":90},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":34,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100652602","satiety-microbiome-appetite-regulation-and-tracking-energy-across-targeted-snacks-acute-postprandial-study-100652602",false,"NCT07776418","Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Acute Postprandial Study","The ZOE SMART EATS (Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks) Acute Postprandial Study: Investigating the Acute Effects of a High-fibre Plant-based Snack Bar on Subjective Postprandial Hunger, Energy Intake and Eating Behaviour in Healthy UK Adults.","SMARTEATS-PP","Inclusion Criteria:\n\n* Willing and able to follow the study protocol\n* Willing and able to provide informed consent\n* Regular consumption of snacks (≥2 per day)\n* Fibre intake \\\u003C20 g\u002Fd\n* Living in the UK\n\nExclusion Criteria:\n\n* Have BMI of less than 18.5 kg\u002Fm² or more than 40 kg\u002Fm²\n* Have an allergy or intolerance to ingredients in the intervention or control snack bars (including inulin) or cannot eat the food products safely and comfortably for any reason\n* Have a personal medical history of inflammatory bowel disease, coeliac disease, Crohn's disease, irritable bowel syndrome, chronic constipation, or chronic diarrhoea\n* Have started a new supplement in the past month, or are unwilling to maintain current supplement use throughout the study\n* Previously purchased any ZOE products (including Daily30, ZOE gut health bar or ZOE app membership).\n* Have taken any medication or product that may modify the measured study outcomes, in the past 3 months (including but not limited to: fibre supplements, antibiotics, non-topical steroids or other immunosuppressive medicines, probiotics or prebiotics, metformin, GLP-1 receptor agonists, lipid-lowering medications such as fibrates, statins, PCSK9 inhibitors, non-steroidal anti-inflammatory drugs)\n* Have used opiate pain medication or a proton pump inhibitor for 8 or more consecutive days during the past 3 months\n* Have experienced a heart attack, stroke or major surgery in the last 2 months\n* Have received treatment for cancer in the last 3 months\n* Are currently pregnant, breastfeeding or planning a pregnancy\n* Are diagnosed with an eating disorder, type 1 diabetes mellitus or type 2 diabetes mellitus",true,"ALL","35 Years","65 Years",{"count":22,"type":23},54,"ESTIMATED","INTERVENTIONAL",[26],"NA","The goal of this clinical trial is to learn how eating different snack foods affects acute hunger, energy intake and eating behaviour in healthy adults. The study will be conducted remotely over 5 days.\n\nThe main questions it aims to answer are:\n\n1. Does eating a snack bar intervention change how hungry participants feel later in the same day?\n2. Does eating a snack bar intervention change participants' energy intake, nutrient intake and eating behaviour on the same day?\n3. Does eating a snack bar intervention change participants mood, energy levels and alertness later in the same day?\n\nResearchers will compare an intervention snack bar to a control snack bar to see if the intervention improves hunger, energy intake, eating behaviour, and other subjective measures.\n\nParticipants will:\n\n* Eat 2 snack bars for breakfast on 2 separate days, with 2 days in between\n* Not eat anything after 9pm the night before each test day\n* Fill out short online surveys (under 5 minutes) before breakfast and at set times over the next 3 hours\n* Not eat for 3 hours after breakfast\n* Write down everything they eat that day",[29,30,31,32,33],"Healthy Participants","Healthy Adult Subject","Healthy Subjects","Healthy Adult Volunteer","Healthy Adult Participants",[35,36,37,38,39,40,41],"Snacks","Snack foods","Dietary intervention","Hunger","Health","Wellbeing","Nutrition study","NOT_YET_RECRUITING","2026-08-19",{"date":45,"type":46},"2026-08-20","ACTUAL",{"date":48,"type":23},"2026-08-14",{"date":50,"type":23},"2026-10",{"name":52,"class":53},"Zoe Global Limited","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":17,"sex":18,"minAge":61,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":24,"phases":64,"briefSummary":65,"conditions":66,"keywords":75,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":5},"100418985","personalized-responses-to-dietary-composition-trial-3-100418985","NCT04735835","Personalized Responses to Dietary Composition Trial 3","Inclusion Criteria:\n\n* Enrolled in the commercial ZOE testing program\n* Any sex\n* Minimum 18 years of age (minimum 19 years of age in Alabama and Nebraska due to state laws)\n* Body mass index (BMI) of greater than or equal to 16.5 kg\u002Fm2.\n* Living in the continental US states, other than in New York (excluded from the ZOE testing product also as they are unable to access the dried blood spot service provided by Quest), or living in the UK\n* Able and willing to comply with the study protocol and provide informed consent.\n* Under care for chronic medical conditions (including eating disorders, type 1 diabetes, type 2 diabetes), and confirm they have checked with their primary care physician that this study is safe for them (US cohort only)\n\nExclusion Criteria:\n\n* Cannot safely eat the pre-made test meals which contain standard US ingredients, e.g. due to allergy or recent gastrointestinal surgery, or are unwilling to consume these foods.\n* Are pregnant.\n* Have had a heart attack (myocardial infarction), stroke\u002Ftransient ischemic attack (TIA), or major surgery in the last two months.\n* Are unable to read and write in English, as the ZOE app is only available in English.","18 Years",{"count":63,"type":23},250000,[26],"The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and individualized dietary advice. The study incorporates both standardized and controlled dietary intervention, for the purpose of testing postprandial responses to specific mixed meals, in addition to a free-living period with a dietary record for measuring responses to a large variety of meals consumed in a realistic context, where the role of external factors (e.g. exercise, sleep, time of day) on postprandial responses may be determined. For the first time this PREDICT study is built on top of a commercial product which will allow access to a much larger group of participants who are already collecting large amounts of data through digital and biochemical devices that can contribute to science.",[67,68,69,70,71,72,73,74],"Diabetes","Heart Diseases","Diet Habit","Diet Modification","Healthy","Obesity","Metabolism","Microbial Colonization",[76,77,78,79,80],"Gut microbiome","Personalised nutrition","Machine learning","Postprandial metabolism","Metabolic health","RECRUITING","2025-04-11",{"date":84,"type":46},"2025-04-16",{"date":86,"type":46},"2020-07-20",{"date":88,"type":23},"2030-01-01",{"name":52,"class":53},""]