[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"acl-reconstruction-aclr-with-a-bone-patellar-tendon-bone-bptb-autograft\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:acl-reconstruction-aclr-with-a-bone-patellar-tendon-bone-bptb-autograft":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100655627","effects-of-criteria-versus-time-based-rehabilitation-on-return-to-play-in-football-players-100655627",false,"NCT07815340","Effects Of Criteria Versus Time-Based Rehabilitation On Return To Play In Football Players","Inclusion Criteria:\n\n* Injury Type: ACL reconstruction, hamstring strain, and ankle sprain.\n* Rehabilitation Phase: Phase 3 for ACL injuries, Phase 1\\&2 for hamstring strains and ankle sprains.\n* Football Activity: Active at club or regional football level\n\nExclusion Criteria:\n\n* History of Major surgery in affected limb\n* Chronic neurological or musculoskeletal disorder\n* Non-football athletes","ALL","18 Years","35 Years",{"count":19,"type":20},52,"ESTIMATED","INTERVENTIONAL",[23],"NA","This randomized controlled trial compares criteria-based rehabilitation (CBR) with time-based rehabilitation (TBR) for football players aged 18-35 with ACL reconstruction, hamstring strain, or ankle sprain. Both groups receive a six-week supervised rehabilitation program; the progression rules differ between groups.",[26,27],"Hamstring Muscle Strain","ACL Reconstruction (ACLR) With a Bone-patellar Tendon-bone (BPTB) Autograft",[29,30,31],"ankle sprain","reinjury","reactive strength","NOT_YET_RECRUITING","2026-09-06",{"date":35,"type":36},"2026-09-11","ACTUAL",{"date":38,"type":20},"2026-09",{"date":40,"type":20},"2027-01-05",{"name":42,"class":43},"Riphah International University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":44},"100649093","cryoneurolysis-in-anterior-cruciate-ligament-reconstruction-aclr-100649093","NCT07731178","Cryoneurolysis in Anterior Cruciate Ligament Reconstruction (ACLR)","Evaluating the Efficacy of Preoperative Cryoneurolysis With Iovera on Postoperative Pain, Function, and Opioid Use Following ACL Reconstruction With Bone-Patellar Tendon-Bone Autograft","Inclusion Criteria:\n\n1. Age 18-45 years\n2. Scheduled for primary ACLR with BPTB autograft\n3. Willingness and ability to participate in Iovera\n4. No chronic opioid use preoperatively\n5. No known neurologic disorders affecting the lower extremity\n6. Capacity and willingness to provide informed consent and comply with follow-up schedules\n\nExclusion Criteria:\n\n1. Prior surgery on the affected knee.\n2. Non-English speaking if validated PRO instruments at the site are only available in English; include validated translations if available and approved.\n3. Contraindications to cryoneurolysis (e.g., cryoglobulinemia, cold urticaria, Raynaud's phenomenon, paroxysmal cold hemoglobinuria) or to local anesthetics.\n4. Active skin infection, dermatitis, or compromised skin integrity at or near treatment sites.\n5. Bleeding diathesis or anticoagulant therapy not compatible with minor percutaneous procedures per institutional policy.\n6. Pregnancy or breastfeeding.\n7. Known peripheral neuropathy or significant sensory deficit of the target region.\n8. Any condition that, in the investigator's judgment, increases risk or interferes with participation\n9. Concomitant use of other opioid drugs or prior chronic use.","45 Years",{"count":54,"type":20},150,[23],"The purpose of this research study is to assess whether cryoneurolysis will help control pain after ACLR surgery and decrease the need of opioid medications. The primary objective is to compare postoperative functional recovery between Iovera and sham arms at 1 month after ACLR.",[27],[59],"ACLR","2026-07-23",{"date":62,"type":36},"2026-07-28",{"date":64,"type":20},"2026-08",{"date":66,"type":20},"2028-08",{"name":68,"class":43},"NYU Langone Health"]