[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adenocarcinoma-of-the-esophagogastric-junction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adenocarcinoma-of-the-esophagogastric-junction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100654498","sino-russian-comparison-of-outcomes-after-proximal-gastrectomy-with-double-tract-reconstruction-100654498",false,"NCT07800819","Sino-Russian Comparison of Outcomes After Proximal Gastrectomy With Double-Tract Reconstruction","Surgical Outcomes and Long-Term Survival of Proximal Gastrectomy With Double-Tract Reconstruction at High-Volume Centers in Russia and China: A Two-Center Retrospective Analysis","RUSCHI-DTR","Inclusion Criteria:\n\n1. Age 18 to 75 years.\n2. Histologically confirmed gastric adenocarcinoma or Siewert type II\u002FIII adenocarcinoma of the esophagogastric junction.\n3. Underwent proximal gastrectomy with double-tract reconstruction.\n4. Surgery performed with curative intent.\n5. At least one valid postoperative follow-up record containing reflux, nutritional, or complication information.\n6. Clinical, pathological, operative, and follow-up data sufficiently complete for analysis, with less than 20 percent missingness in key variables.\n\nExclusion Criteria:\n\n1. Previous gastric or esophageal surgery, except limited endoscopic treatment such as endoscopic mucosal resection.\n2. Synchronous or metachronous malignancy, except cured non-melanoma skin cancer or cervical carcinoma in situ.\n3. Complete absence of follow-up data.\n4. Double-tract reconstruction not completed or changed to another reconstruction method.\n5. Severe preoperative reflux disease, defined as GERD-Q score greater than 8 with a requirement for long-term medication.","ALL","18 Years","75 Years",{"count":21,"type":22},250,"ESTIMATED","OBSERVATIONAL","This two-center retrospective observational cohort study compares Chinese and Russian patients who underwent curative proximal gastrectomy with double-tract reconstruction for proximal gastric adenocarcinoma or Siewert type II\u002FIII adenocarcinoma of the esophagogastric junction. The study evaluates postoperative reflux, nutritional status, perioperative outcomes, complications, and long-term survival. Propensity score matching will be used to improve comparability between the two cohorts.",[26,27],"Gastric Adenocarcinoma","Adenocarcinoma of the Esophagogastric Junction",[29,30,31,32],"Proximal gastrectomy","Double-tract reconstruction","Reflux esophagitis","Postoperative nutrition","NOT_YET_RECRUITING","2026-08-30",{"date":36,"type":37},"2026-09-02","ACTUAL",{"date":39,"type":22},"2026-08-15",{"date":41,"type":22},"2027-08-15",{"name":43,"class":44},"The First Affiliated Hospital with Nanjing Medical University","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":4},"100600300","intraoperative-margin-techniques-for-esophagogastric-junction-adenocarcinoma-a-controlled-study-100600300","NCT07095699","Intraoperative Margin Techniques for Esophagogastric Junction Adenocarcinoma: A Controlled Study","An Exploratory, Parallel Controlled Study to Explore the Effectiveness of Intraoperative Margin Exploration Techniques for Adenocarcinoma of the Esophagogastric Junction","Inclusion Criteria:\n\n* Patients clinically diagnosed with adenocarcinoma of the esophagogastric junction (AEG):\n\nIncluding patients with Siewert type II and III AEG; Including patients in cT1 stage (recommended esophageal resection margin distance ≥1.5cm) and cT2 and above (recommended esophageal resection margin distance ≥3cm);\n\n* Plan to receive surgical resection of AEG;\n* Patients voluntarily participated in this study and signed the informed consent form;\n\nExclusion Criteria:\n\n* Patients who are allergic to methylene blue and fluorescein sodium;\n* Patients with severe cardiovascular or circulatory system diseases and cannot tolerate surgery;\n* Participated in other clinical trials of research drugs or devices in the past month;\n* Unable to understand the test requirements or unable to complete the study follow-up plan;\n* Pregnant and lactating women;\n* Patients who are unable to complete follow-up due to mental illness, cognitive or emotional disorders;\n* Subjects who are considered by the researchers to be unsuitable for participating in the study.","65 Years",{"count":54,"type":22},314,"INTERVENTIONAL",[57],"NA","The goal of this clinical trial is to learn if the EndoScell Scanner (ES) imaging system can accurately assess tumor-free surgical margins during surgery for adenocarcinoma of the esophagogastric junction (AEG), compared with standard frozen-section pathology.\n\nThe main questions it aims to answer are:\n\n* Is ES non-inferior to intraoperative frozen-section pathology in identifying positive or negative tumor margins?\n* Does ES shorten the time needed for margin assessment and reduce the number of additional tissue resections required?\n\nResearchers will compare an ES-assisted surgical arm with a conventional frozen-section arm to see if ES improves margin accuracy, shortens operative time, and increases the rate of complete (R0) tumor removal.\n\nParticipants will\n\n* undergo standard AEG resection with randomized assignment to either ES or frozen-section margin checks;\n* allow collection of margin tissue samples for ES, frozen-section, and final paraffin pathology;\n* attend routine follow-up visits for up to 2 years to monitor for local recurrence.",[27],[61,62,63],"AEG resection","fluorescent","microscope","2025-07-23",{"date":66,"type":37},"2025-07-31",{"date":68,"type":22},"2025-08-15",{"date":70,"type":22},"2028-06-30",{"name":72,"class":44},"Fudan University"]