[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adhesive-capsulitis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adhesive-capsulitis":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,33,0,25,[9,51,82,111,133,156,186,217,240,262,284,308,330,361,392,417,438,459,484,509,532,560,588,610,633],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100646209","comparison-of-transcatheter-arterial-microembolization-and-corticosteroid-injection-and-for-treatment-of-frozen-shoulder-100646209",false,"NCT07696923","Comparison of Transcatheter Arterial Microembolization and Corticosteroid Injection and for Treatment of Frozen Shoulder","Inclusion Criteria:\n\n* 1). age between 18 to 80 years old;\n* 2). shoulder pain for ≥ 1 month;\n* 3). \\> 30% loss of passive range of motion (ROM) of the affected shoulder in external rotation and\u002For abduction, comparing with the sound side;\n* 4). pain VAS on maximal passive external rotation or abduction \\> 4;\n* 5). showing willing to receive TAME, or shoulder joint injection, and attend regular physical therapy programs for 4 weeks.\n* 6). an empty or soft end feel during passive external rotation or abduction and\u002For night or rest pain.\n\nExclusion Criteria:\n\n* 1). severe systemic disorders including cancer, stroke, or cardiopulmonary diseases;\n* 2). uncontrolled DM;\n* 3). rotator cuff tear or calcification of the affected shoulder;\n* 4). fracture, dislocation, or arthritis of the shoulder due to rheumatic disorders; - 5). a history of allergy to local anesthetics, corticosteroids, imipenem\u002Fcilastatin sodium or contrast medium;\n* 6). pregnancy;\n* 7). corticosteroid joint or subdeltoid bursa injection of the affected shoulder during the preceding three months;\n* 8). receiving TAME of the affected shoulder during the preceding six months.","ALL","18 Years","80 Years",{"count":20,"type":21},94,"ESTIMATED","INTERVENTIONAL",[24],"NA","Objectives： This study aims to compare the efficacy of transcatheter arterial microembolization (TAME) and corticosteroid injection for treatment of frozen shoulder.\n\nBackground： Frozen shoulder (adhesive capsulitis) is a common condition that leads to significant functional impairment and reduced quality of life. Current treatment options are diverse, including pharmacological therapy, physical rehabilitation, corticosteroid injection, hydrodilatation, and the more recently developed transcatheter arterial microembolization (TAME). Corticosteroid injection, due to its anti-inflammatory effects, has been shown in numerous clinical studies to provide short-term pain relief and improved range of motion; however, its benefits are often limited to several weeks or months, and some patients continue to experience persistent symptoms. In contrast, TAME has emerged as a novel treatment for musculoskeletal disorders by targeting abnormal neovascularization and inflammatory processes in the affected tissues, there by achieving pain reduction. Multiple studies from both international and domestic medical centers have demonstrated its safety and efficacy, though most reports focus on case reports or case series observational outcomes. To date, there is a lack of clinical trials directly comparing the therapeutic outcomes of TAME versus corticosteroid injection in patients with frozen shoulder.\n\nStudy Design： This study is a single-center, prospective, randomized controlled trial (RCT).\n\nMethods： A total of 94 patients diagnosed with frozen shoulder in the freeing stage will be recruited from the Department of Physical Medicine and Rehabilitation at Shin Kong Hospital. Eligible patients will be randomly assigned to either the transcatheter arterial microembolization (TAME) group and the corticosteroid injection (CS) group.\n\nThe arterial microvascular embolization group will receive one treatment, while the corticosteroid injection group will receive two corticosteroid injections into the shoulder joint and subacromial bursa, with a two-week interval between the two injections. Additionally, all patients in both groups will undergo 4 weeks of physical therapy.\n\nClinical assessments will be conducted at baseline and at 1, 2, 4, and 6 months after initiation of treatment, including Shoulder Pain and Disability Index (SPADI), the Visual Analogue Scale (VAS) for pain, Shoulder Disability Questionnaire (SDQ), active and passive range of motion (ROM), Short Form-36 (SF-36) for quality of life, and patient-reported global efficacy. Patients will be followed for 6 months after completion of treatment, and statistical analyses will be performed to evaluate the therapeutic outcomes.\n\nEffect： Efficacy comparison: Both the TAME and corticosteroid injection are expected to effectively improve pain, function, and quality of life. However, the TAME group is anticipated to demonstrate greater pain relief and better recovery of shoulder function compared with the corticosteroid injection group, with longer-lasting therapeutic effects.\n\nSafety: Both treatments are considered safe. TAME may lead to temporary local pain, transient radial artery spasm, or low-grade fever, all of which are self-limiting or manageable with supportive care. Corticosteroid injection may be associated with transient hyperglycemia, local injection site pain, or, rarely, infection. No permanent or severe adverse events are expected.\n\nExploration of prognostic factors: By comparing treatment responses between the two groups and incorporating clinical characteristics, imaging findings, and treatment outcomes, this study aims to identify potential prognostic factors that may predict therapeutic response, thereby guiding future clinical decision-making.\n\nIntermediate follow-up results: At 1 to 3 months post-treatment, both groups are expected to show improvement in the clinical outcomes, but the TAME group is expected to demonstrate superior effect compared with that of the corticosteroid injection group.",[27,28,29,30,31],"Frozen Shoulder","Chronic Pain","Adhesive Capsulitis","Transcatheter Arterial Microembolization","Corticosteroid Injection",[33,34,35,36,37],"frozen shoulder","chronic pain","adhesive capsulitis","transcatheter arterial microembolization (TAME)","corticosteroid injection","RECRUITING","2026-08-04",{"date":41,"type":42},"2026-08-05","ACTUAL",{"date":44,"type":42},"2026-08-01",{"date":46,"type":21},"2030-12-31",{"name":48,"class":49},"Shin Kong Wu Ho-Su Memorial Hospital","OTHER",1,{"id":52,"slug":53,"hasResults":12,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":12,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":50},"100649535","effect-of-hormone-replacement-therapy-on-physiotherapy-outcomes-in-postmenopausal-women-with-frozen-shoulder-100649535","NCT07736027","Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder","The Effects of Hormone Replacement Therapy on Clinical and Functional Outcomes in Postmenopausal Women With Frozen Shoulder","Inclusion Criteria:\n\n* Postmenopausal female patients aged 40 to 60 years.\n* Shoulder pain at rest and during activities of daily living lasting for more than 3 months.\n* Clinical diagnosis of Stage I or Stage II frozen shoulder (adhesive capsulitis).\n* Passive range of motion (ROM) loss of greater than 25% compared to the unaffected shoulder in at least two movement planes (flexion, abduction, internal rotation, or external rotation).\n* Reduced range of motion of less than 50% compared to the unaffected side in at least one movement direction (flexion, abduction, internal rotation, or external rotation).\n* Increased restriction of external and internal rotation during glenohumeral abduction from 45 to 90 degrees.\n\nExclusion Criteria:\n\n* Passive external rotation range of motion of less than 30 degrees (\\\u003C30°).\n* Presence of glenohumeral arthritis confirmed by radiography.\n* History or presence of inflammatory joint disease.\n* History of malignancy or active cancer diagnosis.\n* Previous treatment for the current shoulder condition (e.g., physiotherapy and rehabilitation, intra-articular injections, or surgical intervention).\n* Baseline shoulder pain score of less than 3 (\\\u003C3) on the Numeric Pain Rating Scale (NPRS).","FEMALE","40 Years","60 Years",{"count":62,"type":21},56,[24],"The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in postmenopausal women diagnosed with frozen shoulder, with and without Hormone Replacement Therapy (HRT). The findings are expected to contribute to personalized treatment planning for postmenopausal women with frozen shoulder and help fill the gap in current literature.",[27,29,66,67,68,69],"Adhesive Capsulitis of the Shoulder","Hormone Replacement Therapy, Post-Menopausal","Exercise","Physical Therapy",[71],"Frozen Shoulder, Adhesive Capsulitis, Hormone Replacement Therapy, Postmenopause, Physical Therapy, Rehabilitation, Pain Catastrophizing, Range of Motion","NOT_YET_RECRUITING","2026-07-28",{"date":75,"type":42},"2026-07-30",{"date":77,"type":21},"2026-09-01",{"date":79,"type":21},"2027-10-01",{"name":81,"class":49},"Istanbul University - Cerrahpasa",{"id":83,"slug":84,"hasResults":12,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":12,"sex":16,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":22,"phases":94,"briefSummary":95,"conditions":96,"keywords":100,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":108,"locationsCount":110},"100648732","spinal-mobilization-with-arm-movement-and-kaltenborn-mobilization-in-adhesive-capsulitis-100648732","NCT07724691","Spinal Mobilization With Arm Movement and Kaltenborn Mobilization in Adhesive Capsulitis","Effects of Spinal Mobilization With Arm Movement and Kaltenborn Mobilization on Pain, Range of Motion, Functional Reaching, and Disability in Adhesive Capsulitis","SMWAM","Inclusion Criteria:\n\n* Age 35-50 years\n* Both male and female genders\n* Pain rating 3 to 7 on NPRS for at least 3 months\n* Idiopathic frozen shoulder\n* Stage II and III frozen shoulder\n* Positive Apley's Scratch test\n* Unilateral frozen shoulder\n* Frozen shoulder with at least 25% restricted ROM\n* Presence of global restriction in passive range of motion (PROM) in a capsular pattern (ER \\> ABD \\> IR)\n\nExclusion Criteria:\n\n* Arthritic shoulder\n* Rotator cuff disease\n* Post-traumatic stiff shoulder\n* Post-CABG shoulder-hand syndrome\n* Post-stroke frozen shoulder\n* Bilateral frozen shoulder\n* Complex Regional Pain Syndrome\n* Any fracture or other injury\n* Any systemic illness\n* Any inflammatory disease (Rheumatoid arthritis, gout)\n* Any neurological disease\n* Frozen Shoulder secondary to Brachial Plexus Injury, Parkinsonism, Ankylosis, Infection, or Arthroplasty\n* Tendon calcification","30 Years","50 Years",{"count":93,"type":21},50,[24],"To compare the effects of spinal mobilization with arm movement and Kaltenborn Mobilization on pain, range of motion, functional reaching, and disability in patients with Adhesive Capsulitis.",[29,27,97,98,99],"Mulligan Mobilization","Spinal Mobilization","Shoulder Pain",[101],"Adhesive capsulitis, Disability, Kaltenborn, Mulligan, Pain, Range of Motion","2026-07-23",{"date":104,"type":42},"2026-07-24",{"date":106,"type":42},"2026-07-01",{"date":77,"type":21},{"name":109,"class":49},"Riphah International University",2,{"id":112,"slug":113,"hasResults":12,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":4,"eligibilityCriteria":117,"healthyVolunteers":12,"sex":16,"minAge":59,"maxAge":118,"enrollmentInfo":119,"targetDuration":4,"studyType":22,"phases":121,"briefSummary":122,"conditions":123,"keywords":124,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":4},"100648661","comparative-effects-of-gongs-and-maitland-mobilization-in-patients-with-adhesive-capsulitis-100648661","NCT07724613","Comparative Effects of Gongs and Maitland Mobilization in Patients With Adhesive Capsulitis","Comparative Effects of Gongs and Maitland Mobilization on Pain, Range of Motion, and Functional Disability in Patients With Adhesive Capsulitis","Inclusion Criteria:\n\n* Adults aged between 40-65 years.\n* Both male and female genders\n* Stage II and III frozen shoulder\n* Positive Apley's Scratch test\n* Pain rating 3 to 7 on NPRS for at least 3 months\n* Frozen shoulder with at least 25% restricted ROM\n\nExclusion Criteria:\n\n* Mental disorders\n* Arthritic shoulder\n* Rotator cuff disease\n* Post-traumatic stiff shoulder\n* Post-CABG shoulder-hand syndrome\n* Post-stroke frozen shoulder\n* Bilateral frozen shoulder\n* Neurological disorders\n* Frozen Shoulder secondary to Brachial Plexus Injury, Parkinsonism, Ankylosis, Infection, or Arthroplasty","65 Years",{"count":120,"type":21},52,[24],"Adhesive capsulitis is a common musculoskeletal disorder characterized by shoulder pain, restricted range of motion (ROM), and functional disability, leading to limitations in daily activities and reduced quality of life. Manual therapy techniques, including Gong's Mobilization and Maitland Mobilization, are widely used in physiotherapy management; however, evidence comparing their effectiveness remains limited.",[29],[125],"Adhesive capsulitis, frozen shoulder, Gong's mobilization, Maitland mobilization, pain, range of motion, functional disability, physiotherapy.","2026-07-21",{"date":104,"type":42},{"date":129,"type":21},"2026-07",{"date":131,"type":21},"2026-12-30",{"name":109,"class":49},{"id":134,"slug":135,"hasResults":12,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":4,"eligibilityCriteria":139,"healthyVolunteers":140,"sex":16,"minAge":59,"maxAge":60,"enrollmentInfo":141,"targetDuration":4,"studyType":22,"phases":143,"briefSummary":144,"conditions":145,"keywords":146,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":50},"100638452","effects-of-gongs-mobilization-with-and-without-nielasher-technique-on-in-adhesive-capsulitis-100638452","NCT07628335","Effects of Gong's Mobilization With and Without Nielasher Technique on in Adhesive Capsulitis","Effects of Gong's Mobilization With and Without Niel Asher Technique on Shoulder Pain, Range of Motion and Disability in Adhesive Capsulitis","Inclusion Criteria:\n\n* Individuals with age group of 40-60 years.\n* Both Females and males individuals.\n* Individuals diagnosed with Frozen shoulder (Adhesive Capsulitis) within stage II and III of frozen shoulder.\n* Individuals with positive capsular pattern (ER\\>Abd\\> IR).\n* Individuals with ROM loss ≥ 25% in at least two planes compared with the noninvolved shoulder\n\nExclusion Criteria:\n\n* Individuals with rotator cuff tears and overuse injury\n* Individuals with inflammatory diseases (Osteoarthritis, Rheumatoid Arthritis, Gout) and Malignancies\n* Individuals Using Corticosteroid Injections or Medications",true,{"count":142,"type":21},46,[24],"Adhesive Capsulitis causes a progressive tightening of the glenohumeral joint capsule, restricting both active and passive movements and resulting in functional impairments. Joint mobilization is an essential component of physical therapy for managing adhesive capsulitis. Two new techniques are emerging in the treatment of Adhesive capsulitis; one of them is called Gong's Mobilization. This technique emphasizes correcting positional faults by applying controlled, dynamic movements to the glenohumeral joint. The other technique, known as Niel-Asher technique is a five-step trigger point therapy which offers a unique, non-invasive holistic approach to address adhesive capsulitis. This study, will be conducted as a randomized clinical trial at Ghurki Trust Teaching Hospital and Hope Rehabilitation Center, it aims to evaluate the effects of Gong's mobilization with and without Niel-Asher technique on shoulder pain, ROM and disability in Adhesive Capsulitis of patients aged 40-60 years. A non-probability convenience sampling method will recruit 46 participants meeting the inclusion criteria only. Participants will be randomly assigned to Group A (Gong's Mobilization) or Group B (Gong's mobilization and and Niel-Asher technique) with interventions given for four weeks. Pain severity will be measured using the Numeric Pain Rating Scale, Range of Motion will be assessed via goniometer, and disability will be evaluated using the SPADI. Statistical analysis using SPSS will compare outcomes between groups at baseline, at two weeks and post-treatment after 4 weeks.",[29],[29,147],"goniometer","2026-06-04",{"date":150,"type":42},"2026-06-05",{"date":152,"type":42},"2025-12-15",{"date":154,"type":21},"2026-07-15",{"name":109,"class":49},{"id":157,"slug":158,"hasResults":12,"nctId":159,"briefTitle":160,"officialTitle":161,"acronym":162,"eligibilityCriteria":163,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":164,"enrollmentInfo":165,"targetDuration":4,"studyType":22,"phases":167,"briefSummary":168,"conditions":169,"keywords":170,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":178,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":50},"100533757","frozen-shoulder-treatment-with-intra-articular-corticosteroid-injection-and-suprascapular-nerve-block-100533757","NCT06229964","Frozen Shoulder Treatment With Intra-Articular Corticosteroid Injection and Suprascapular Nerve Block","A Double Blinded Randomized Controlled Trial (RCT) Exploring the Additional Effect of a Suprascapular Nerve Block in Combination With an Intra-Articular Corticosteroid Injection in Patients With Frozen Shoulder","FROSTBLOCK","Inclusion Criteria:\n\n* Written informed consent to participate in the study must be obtained from the subject prior to initiation of any study-mandated procedure\n* Suffering from Frozen Shoulder, defined as: Frozen shoulder is a self-limiting disease characterized by pain and functional restriction in both active and passive shoulder motion lasting more than 1 month, for which radiographic findings of the shoulder joint are unremarkable.\n* Dutch or French speaking persons\n* Age ≥ 18 years\n\nExclusion Criteria:\n\n* Subjects with posttraumatic or postsurgical stiff shoulder syndrome\n* History of trauma at the onset of symptoms\n* Subjects with rheumatologic or neurologic disease involving the shoulder\n* Subjects with cervical radiculopathy\n* Coagulation disorder\n* Hypersensitivity to local anesthetics or MRI contrast agent\n* Inability to understand the study procedures\n* Psychiatric illness\n* Pregnancy\n* Subjects who have received prior SSNB in the homolateral shoulder\n* Subjects who have received an IACI in the homolateral shoulder in the 3 months before inclusion• Systematic yeast infections\n* Hypovolaemia\n* Infections at the injection site\n* Medical history of malignant hyperthermia, major conduction disorders, acute cardiac decompensation, shock conditions, convulsions\n\nControl subjects for the diagnostic accuracy part of the study protocol\n\n* Inclusion criteria:\n* Written informed consent to participate in the study must be obtained from the sub-ject prior to initiation of any study-mandated procedure\n* Subjects suffering from shoulder pain that do not fulfill the diagnostic criteria of Frozen Shoulder\n* Dutch or French speaking persons\n* Age ≥ 18 years\n* Contralateral shoulder of Frozen Shoulder subjects\n* Exclusion criteria\n* Subjects with posttraumatic or postsurgical stiff shoulder syndrome\n* History of trauma at the onset of symptoms\n* Subjects with rheumatologic or neurologic disease involving the shoulder\n* Subjects with cervical radiculopathy\n* Coagulation disorder or treatments with anticoagulants\n* Hypersensitivity to MRI contrast agent\n* Inability to understand the study procedures\n* Psychiatric illness\n* Pregnancy\n* Systematic yeast infections\n* Hypovolaemia\n* Infections at the injection site\n* Medical history of malignant hyperthermia, major conductin disorders, acute cardi-ac decompensation, shock conditions, convulsions","99 Years",{"count":166,"type":21},110,[24],"Frozen shoulder remains a challenging disease to treat as pain and loss of range of motion can persist for many months or even years. This loss of function can have a severe impact on the patient's activities, participation and overall quality of life.\n\nThe use of ultrasound-guided (USG) suprascapular nerve blocks (SSNB) and\u002For intra-articular corticoid injections (IACI) has been supported by many studies. However, double blinded randomized clinical trials using a combination of SSNB and IACI are rare.\n\nThe primary objective of this study is to compare the effectiveness of a glenohumeral IACI combined with a SSNB, compared to a glenohumeral IACI combined with a sham SSNB. Outcome measures of interest are shoulder-related disability reported by the patients, shoulder pain and shoulder stiffness. These outcome parameters will be compared between both treatment arms with an intention-to-treat analysis.\n\nAs key secondary objectives, the investigators aim to identify which physical examination tests, or combinations of those, are correlated with MRI diagnostic criteria and favor a more positive evolution. Finally, through predictive analysis the investigators will try to establish which patients benefit the most from the combined SSNB + IACI.",[27,29],[27,66,171,172,173,174,175,176],"Intra-articular corticosteroid injection","ultra-sound guided injection","suprascapular nerve block","Joint Diseases","Musculoskeletal Diseases","Bursitis","2026-05-28",{"date":179,"type":42},"2026-06-01",{"date":181,"type":42},"2025-02-28",{"date":183,"type":21},"2028-05-31",{"name":185,"class":49},"Universitair Ziekenhuis Brussel",{"id":187,"slug":188,"hasResults":12,"nctId":189,"briefTitle":190,"officialTitle":191,"acronym":4,"eligibilityCriteria":192,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":193,"enrollmentInfo":194,"targetDuration":4,"studyType":22,"phases":196,"briefSummary":197,"conditions":198,"keywords":202,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":214,"locationsCount":50},"100630865","efficacy-of-chemically-distinct-nonsteroidal-anti-inflammatory-drugs-nsaids-and-pain-phenotypes-in-adhesive-capsulitis-100630865","NCT07493226","Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis","Comparative Efficacy of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) With Distinct Chemical Structures in Shoulder Adhesive Capsulitis and the Role of Pain Phenotypes","Inclusion Criteria:\n\n1. Being between 18-75 years of age\n2. Having shoulder pain that has lasted for at least one month and being diagnosed with primary frozen shoulder\n3. Having a VAS pain level ≥ 4\u002F10\n4. Having ≥30 degrees of range of motion restriction in at least two planes (flexion, abduction, or external rotation)\n5. Not having any exclusion criteria and agreeing to participate in the study voluntarily\n\nExclusion Criteria:\n\n1. Patients with a history of shoulder trauma, those with musculoskeletal disorders characterized by pain and loss of function in the affected extremity (such as lateral epicondylitis, flexor tendon injury, de Quervein's tenosynovitis)\n2. Presence of neurological involvement such as stroke, brachial plexus injury, Parkinson's disease, and cervical spine injury with or without radiculopathy\n3. History of shoulder surgery, malignancy or tumor in the shoulder, those who have undergone shoulder manipulation\n4. Presence of shoulder arthritis, rotator cuff tear or other shoulder injuries, thoracic outlet syndrome\n5. Systemic disease affecting the shoulder region, severe degeneration or trauma (e.g., osteoarthritis, rheumatoid arthritis, history of labrum or articular cartilage injuries), inflammatory rheumatic diseases\n6. Those who have received steroid injections into the affected extremity within the last 3 months, those using oral steroids or NSAIDs, those receiving any surgical or interventional treatment, or Planned individuals:\n7. Those who are pregnant or lactating\n8. Those with uncontrolled diabetes, heart failure, uncontrolled systemic disease (liver disease, chronic kidney failure, significant endocrine disorders, etc.)\n9. Those with communication problems, severe psychiatric disorders\n10. Those allergic to NSAIDs or with any contraindications\n11. Those with bleeding, coagulation disorders, stomach ulcers, or symptomatic gastritis","75 Years",{"count":195,"type":21},120,[24],"Patients aged 18-75 years who present to a tertiary rehabilitation hospital with shoulder pain and restricted range of motion, and who consent to participate, will be included in the study. Eligibility will be determined based on predefined inclusion and exclusion criteria.\n\nEligible patients will be randomly assigned to receive one of several nonsteroidal anti-inflammatory drugs (NSAIDs) with differing chemical properties (e.g., diclofenac, meloxicam, or indomethacin), in combination with a home-based exercise program for shoulder adhesive capsulitis. Patients' sociodemographic data, as well as detailed clinical and examination findings and baseline outcomes, will be recorded. Patients will be informed about their condition, and modifications to activities of daily living will be recommended.Patients' pain phenotypes (nociceptive, neuropathic, nociplastic) will be categorized based on clinical history and questionnaires, and it will be determined which pain types derive greater benefit from NSAIDs.\n\nFollow-up assessments will be conducted at the end of the first and second weeks. At the first-week follow-up, pain intensity will be evaluated using the Visual Analog Scale (VAS). If the treatment is deemed effective (defined as a ≥3-point reduction or ≥50% decrease in VAS), the same NSAID will be continued for an additional week; otherwise, it will be switched to an alternative NSAID with a different biochemical profile (group). The outcomes assessments will be performed by a blinded evaluator to minimize bias.",[27,29,99,199,200,201],"NSAID (Non-Steroidal Anti-Inflammatory Drug)","Nociplastic Pain","Neuropathic Pain",[33,35,203,204,205,206],"shoulder pain","pain phenotypes","exercises","Nonsteroidal Anti-Inflammatory Drugs","2026-05-11",{"date":209,"type":42},"2026-05-14",{"date":211,"type":42},"2026-04-01",{"date":213,"type":21},"2027-03-30",{"name":215,"class":216},"Konya Beyhekim Training and Research Hospital","OTHER_GOV",{"id":218,"slug":219,"hasResults":12,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":4,"eligibilityCriteria":223,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":193,"enrollmentInfo":224,"targetDuration":4,"studyType":22,"phases":226,"briefSummary":227,"conditions":228,"keywords":229,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":235,"startDateStruct":236,"completionDateStruct":237,"leadSponsor":239,"locationsCount":50},"100630864","usg-guided-shoulder-injections-in-frozen-shoulder-100630864","NCT07493213","USG-Guided Shoulder Injections in Frozen Shoulder","Effectiveness of USG-Guided Shoulder Injections as an Adjunct to a Home Exercise Program in the Conservative Management of Painful Frozen Shoulder and Its Association With Pain Phenotypes","Inclusion Criteria:\n\nAge between 18 and 75 years and willingness to participate in the study\n\nPresence of shoulder pain lasting at least 3 months and a diagnosis of primary frozen shoulder\n\nPain intensity ≥ 4\u002F10 on the Visual Analog Scale (VAS), resistant to medical treatment\u002Fanalgesics\n\nRestriction of ≥30 degrees in at least two planes of shoulder motion (flexion, abduction, or external rotation)\n\n\\-\n\nExclusion Criteria:\n\n* History of shoulder trauma\n\nPresence of neurological conditions such as stroke, brachial plexus injury, Parkinson's disease, or cervical spine pathology with or without radiculopathy\n\nHistory of shoulder surgery, shoulder malignancy or tumor, or prior shoulder manipulation\n\nPresence of shoulder arthritis, rotator cuff tear, other shoulder injuries, or thoracic outlet syndrome\n\nSystemic diseases affecting the shoulder, severe degeneration or trauma (e.g., osteoarthritis, rheumatoid arthritis, labral or articular cartilage injuries), or inflammatory rheumatic diseases\n\nSteroid injection to the affected extremity within the last 3 months, use of oral steroids or NSAIDs, or ongoing surgical\u002Finterventional treatment\n\nPregnancy or lactation\n\nUncontrolled diabetes, heart failure, or uncontrolled systemic diseases (e.g., liver failure, chronic kidney disease, significant endocrine disorders)\n\nCommunication problems or severe psychiatric disorders",{"count":225,"type":21},68,[24],"Frozen shoulder (adhesive capsulitis) is characterized by pain and a progressive restriction of both active and passive shoulder range of motion, significantly impairing daily activities and quality of life. This study aims to evaluate the effectiveness of USG-guided shoulder injections, when added to a home-based exercise program, in the conservative management of patients with chronic, painful frozen shoulder.\n\nIn this prospective randomized study, patients diagnosed with painful frozen shoulder will be included. In addition to a standardized home-based exercise program, patients will receive either USG-guided suprascapular nerve block alone or a combination of suprascapular nerve block and subacromial injection. The effects of these approaches on clinical outcomes will be assessed over a 20-week follow-up period.\n\nPrimary outcome measures include pain intensity assessed by the Visual Analog Scale (VAS), functional status evaluated by the Shoulder Pain and Disability Index (SPADI), and shoulder range of motion. Secondary outcomes include depression level (Beck Depression Inventory), sleep quality, pain phenotype (nociplastic, neuropathic, or nociceptive), hand grip strength, ultrasonographic findings ( (coracohumeral ligament thickness, subacromial bursa thickness) , and patient satisfaction (subjective impression of improvement).\n\nThe results of this study are expected to provide evidence on the comparative effectiveness and additional benefits of different shoulder injection approaches when combined with home-based exercise therapy in patients with chronic frozen shoulder.",[27,29,99,200,201],[27,29,230,231,99,232,233,234,204,205],"Shoulder Injection","Home Exercise Program","Range of Motion","SPADI","Ultrasound-Guided Injection",{"date":209,"type":42},{"date":211,"type":42},{"date":238,"type":21},"2027-06-30",{"name":215,"class":216},{"id":241,"slug":242,"hasResults":12,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":4,"eligibilityCriteria":246,"healthyVolunteers":12,"sex":16,"minAge":247,"maxAge":248,"enrollmentInfo":249,"targetDuration":4,"studyType":22,"phases":251,"briefSummary":252,"conditions":253,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":254,"lastUpdatePostDateStruct":255,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":50},"100640462","effect-of-adding-latissimus-dorsi-myofascial-release-to-scapular-proprioceptive-neuromuscular-facilitation-on-pain-disability-and-range-of-motion-in-adhesive-capsulitis-100640462","NCT07588087","Effect of Adding Latissimus Dorsi Myofascial Release to Scapular Proprioceptive Neuromuscular Facilitation on Pain, Disability, and Range of Motion in Adhesive Capsulitis","Effect of Adding Latissimus Dorsi Myofascial Release to Scapular Proprioceptive Neuromuscular Facilitation on Pain, Disability, and Range of Motion in Adhesive Capsulitis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* 1\\. Age between 35 and 70 years.\n* Both male and female participants.\n* Stiffening (Stage II) phase of frozen shoulder.\n* Pain intensity ≥ 4\u002F10 on NPRS during shoulder movement.\n* Unilateral shoulder involvement.\n* Presence of capsular pattern:ER \\> ABD \\> IR limitation\n* Apley's Scratch Test\n* Limited both ROMs\n* Symptom duration between 3 and 9 months.(Di Mascio et al., 2024)\n\nExclusion Criteria:\n\n* Secondary adhesive capsulitis due to trauma or surgery\n* History of shoulder fracture or dislocation.\n* Bilateral frozen shoulder.\n* Active systemic inflammatory or neurological disease\n* Recent intra-articular corticosteroid injection (within last 3 months)\n* Current anticoagulation therapy or bleeding disorders.\n* Pregnant females.","35 Years","70 Years",{"count":250,"type":21},58,[24],"This randomized controlled trial aims to compare the effects of scapular proprioceptive neuromuscular facilitation (PNF) alone versus PNF combined with latissimus dorsi myofascial release on pain, range of motion, and functional disability in patients with stage II adhesive capsulitis; a condition characterized by capsular stiffness, pain, and restricted shoulder mobility, with outcomes assessed using NPRS, goniometry, and SPADI over a 6-week intervention period.",[29],"2026-05-08",{"date":209,"type":42},{"date":257,"type":42},"2026-04-05",{"date":259,"type":21},"2026-06-08",{"name":261,"class":49},"Ibadat International University, Islamabad",{"id":263,"slug":264,"hasResults":12,"nctId":265,"briefTitle":266,"officialTitle":267,"acronym":268,"eligibilityCriteria":269,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":270,"targetDuration":4,"studyType":22,"phases":272,"briefSummary":273,"conditions":274,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":275,"lastUpdatePostDateStruct":276,"startDateStruct":278,"completionDateStruct":280,"leadSponsor":282,"locationsCount":50},"100529628","evaluation-of-the-efficacy-of-suprascapular-nerve-block-in-adhesive-capsulitis-100529628","NCT06176248","Evaluation of the Efficacy of Suprascapular Nerve Block in Adhesive Capsulitis","Evaluation of the Efficacy of Suprascapular Nerve Block in Adhesive Capsulitis: a Randomized Controlled Superiority Trial","BAC-Reims","Inclusion Criteria:\n\n* Patient treated for adhesive capsulitis corresponding to a loss of passive amplitude of more than 20° in external rotation elbow to body and\u002For abduction in relation to the contralateral shoulder.\n* Patient over 18 years of age\n* Patient covered by a social security scheme\n* Presence of an accompanying person on the day of the procedure for the return trip\n* Patient having signed the consent form to participate in the study\n\nExclusion Criteria:\n\n* Patient protected by law\n* Pregnant women\n* Patient who has had shoulder surgery less than six months old\n* Patient unable to undergo rehabilitation within one month of surgery\n* Allergy to one of the products used (anesthetic, iodinated contrast medium)\n* Neuro-orthopedic disorder hampering clinical recovery\n* Hemostasis disorder contraindicating block (no discontinuation of anticoagulants according to SFAR recommendations, congenital hemostasis disorder)",{"count":271,"type":21},62,[24],"This is a double-blind interventional superiority study evaluating the efficacy of suprascapular nerve block in addition to conventional therapies for adhesive capsulitis.\n\nAdhesive capsulitis is a pathology that results in reduced shoulder mobility due to retraction of the periarticular capsule. It may be primary or secondary to traumatic or neurological events, or associated with diabetes in particular.\n\nThe usual treatment includes re-education sessions to improve joint amplitude and restore shoulder mobility. In persistent forms, intra-articular injection of cortisone is combined with distension of the capsule with a local anaesthetic under radiographic control.\n\nIn some countries, subscapular nerve block (reversible anaesthesia) is used to improve pain. The combination of arthrodistension and subscapular nerve block has never been performed to accelerate the healing process.\n\nThe aim of this study is to compare the performance of these two procedures together against the reference technique alone on time to improvement with the number of patients improved at one month according to the Constant score.\n\nThis score is used to assess shoulder pain and function, with a significant improvement above eight points.",[29],"2026-05-05",{"date":277,"type":42},"2026-05-06",{"date":279,"type":42},"2024-10-11",{"date":281,"type":21},"2027-03",{"name":283,"class":49},"CHU de Reims",{"id":285,"slug":286,"hasResults":12,"nctId":287,"briefTitle":288,"officialTitle":288,"acronym":4,"eligibilityCriteria":289,"healthyVolunteers":12,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":290,"targetDuration":4,"studyType":22,"phases":292,"briefSummary":293,"conditions":294,"keywords":295,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":301,"lastUpdatePostDateStruct":302,"startDateStruct":303,"completionDateStruct":305,"leadSponsor":307,"locationsCount":50},"100638645","effects-of-gongs-mobilization-and-proprioceptive-neuromuscular-facilitation-in-patients-with-adhesive-capsulitis-100638645","NCT07576127","Effects of Gongs Mobilization and Proprioceptive Neuromuscular Facilitation in Patients With Adhesive Capsulitis","Inclusion Criteria:\n\n* Females in the age group between 40-60 years.\n* Diagnosed with Unilateral frozen shoulder.\n* Patients in frozen stage (progressive loss of ROM, marked stiffness with gradual pain reduction).\n* More than 25% painful limitation of GH ROM in two planes, more than 50% in external rotation(arm at 0 degree of abduction).\n\nExclusion Criteria:\n\n* History of surgery on the affected shoulder.\n* Patients having any cervical or thoracic problem.\n* Painful, stiff shoulder after severe trauma, inflammatory diseases such as rheumatoid arthritis and malignancies.\n* Recent fractures in and around the shoulder.\n* Rotator cuff disorder.",{"count":291,"type":21},44,[24],"The randomized controlled trail aims is to evaluate the outcome of Gongs mobilization and PNF in patients with adhesive capsulitis. The significance of this study is to compare Gong's mobilization technique with proprioceptive neuromuscular facilitation (PNF) compare their effects on pain, range of motion, and functional disability. The sample size was calculated with G-power. This study would include total 44 female participants aged 40-60 years will be recruited and randomly assigned to two groups. Group A(Gongs mobilization+ conventional therapy)and Group B(PNF+ Conventional therapy). Intervention will be provided for 4 weeks 3 session per week. Primary outcome measures are pain, ROM and functional disability via NPRS, Goniometer and U-SPADI. Outcomes will be reassessed at baseline, after 2nd week, and after 4th week.",[29],[296,297,298,299,300],"Pain","ROM","Functional Disability","Gongs Mobilization","PNF","2026-05-04",{"date":254,"type":42},{"date":304,"type":42},"2025-09-01",{"date":306,"type":21},"2026-05-15",{"name":109,"class":49},{"id":309,"slug":310,"hasResults":12,"nctId":311,"briefTitle":312,"officialTitle":313,"acronym":4,"eligibilityCriteria":314,"healthyVolunteers":12,"sex":16,"minAge":315,"maxAge":4,"enrollmentInfo":316,"targetDuration":4,"studyType":22,"phases":317,"briefSummary":318,"conditions":319,"keywords":320,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":322,"lastUpdatePostDateStruct":323,"startDateStruct":325,"completionDateStruct":326,"leadSponsor":328,"locationsCount":50},"100630324","effects-of-nunchaku-exercise-for-improving-frozen-shoulder-100630324","NCT07486193","Effects of Nunchaku Exercise for Improving Frozen Shoulder","Effects of Nunchaku Exercise on Adhesive Capsulitis (Frozen Shoulder) in Middle-aged and Older Adults: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Ethnic Chinese;\n* Age 45 years or above;\n* Diagnosed with Adhesive Capsulitis (Frozen Shoulder) and currently in the thawing stage.\n\nExclusion Criteria:\n\n* Presence of secondary causes of shoulder stiffness, including recent trauma, post-surgical stiffness, or structural lesions such as full-thickness rotator cuff tears or severe glenohumeral arthritis;\n* Receipt of recent shoulder treatments known to influence short-term outcomes, including corticosteroid injections within the past three months, hydrodilatation, manipulation under anesthesia, arthroscopic capsular release within the past six months, or structured shoulder physiotherapy within the past three months;\n* Presence of somatic conditions that limit their ability to participate safely in exercise (e.g., inability to walk without an assistive device).","45 Years",{"count":93,"type":21},[24],"The goal of this clinical trial is to investigate if nunchaku exercise works to treat adhesive capsulitis, or frozen shoulder in middle-aged or older adults. It will also learn about the adherence of this exercise intervention. The main questions it aims to answer are:\n\n* Does practicing nunchaku exercises help reduce shoulder pain and improve shoulder movement?\n* Do people stick with nunchaku exercises better, and spend more time practicing on their own, compared with standard exercises for alleviating frozen-shoulder?\n\nResearchers will compare nunchaku exercise to standard exercises for alleviating frozen-shoulder to see if nunchaku exercise works to alleviate frozen shoulder.\n\nParticipants will:\n\n* Join small group exercise classes for 12 weeks, doing either nunchaku based exercises or standard exercises designed to help relieve frozen shoulder.\n* Have their shoulder pain and movement checked three times:\n\n  * before training\n  * after 6 weeks of training,\n  * after finishing the 12 week program, and\n  * 12 weeks after the program ends.\n* Keep a record of their home practice time.",[29],[27,321,35],"Nunchaku exercise","2026-04-14",{"date":324,"type":42},"2026-04-17",{"date":322,"type":42},{"date":327,"type":21},"2026-12-31",{"name":329,"class":49},"Chinese University of Hong Kong",{"id":331,"slug":332,"hasResults":12,"nctId":333,"briefTitle":334,"officialTitle":335,"acronym":336,"eligibilityCriteria":337,"healthyVolunteers":12,"sex":16,"minAge":338,"maxAge":248,"enrollmentInfo":339,"targetDuration":341,"studyType":342,"phases":4,"briefSummary":343,"conditions":344,"keywords":345,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":357,"leadSponsor":359,"locationsCount":50},"100631025","electrophysiologic-changes-after-extended-360-capsular-release-100631025","NCT07495306","Electrophysiologic Changes After Extended 360° Capsular Release","Electrophysiological Evidence of Neural Function Improvement After Extended Arthroscopic Circumferential Capsular Release for Adhesive Capsulitis","FROZEN-EMG","Inclusion Criteria:\n\n* Age between 21 and 70 years\n* Diagnosis of adhesive capsulitis (frozen shoulder)\n* Persistent symptoms despite conservative treatment (e.g., physical therapy, medication, or intra-articular injections)\n* Planned arthroscopic capsular release surgery\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Known peripheral neuropathy\n* Previous brachial plexus injury\n* History of ipsilateral shoulder neurovascular surgery\n* Previous proximal brachial plexus surgery\n* Coagulation disorders\n* Active infection\n* Pregnancy","21 Years",{"count":340,"type":21},15,"12 Weeks","OBSERVATIONAL","Frozen shoulder (adhesive capsulitis) is a condition characterized by shoulder pain and restricted range of motion, significantly impairing daily living activities. In cases that do not respond to conservative treatment, arthroscopic capsular release is an effective surgical treatment option. The 360° capsular release technique, performed by some surgeons, involves release of the inferior capsule and therefore carries a potential risk of nerve injury due to the anatomical proximity of neurovascular structures such as the axillary nerve. In addition, surgical manipulations performed around the coracoid process may exert mechanical or compressive effects on the musculocutaneous nerve and its sensory continuation, the lateral antebrachial cutaneous nerve, due to their close relationship with the lateral cord of the brachial plexus.\n\nThe aim of this prospective, single-center observational clinical study is to objectively evaluate the morphological and functional effects of inferior capsular release and coracoid region dissection performed during arthroscopic 360° capsular release surgery on the axillary and musculocutaneous nerves, using electromyography (EMG) and nerve conduction studies (NCS) in patients with frozen shoulder.\n\nPatients aged 21-70 years with a diagnosis of frozen shoulder who have not responded to conservative treatments and are scheduled for arthroscopic capsular release will be included in the study. EMG and NCS assessments will be performed at the preoperative baseline, and at 12 weeks postoperatively. For the axillary nerve, the deltoid and teres minor muscles will be evaluated; for the musculocutaneous nerve, the biceps brachii and brachialis muscles will be assessed. Additionally, sensory conduction of the lateral antebrachial cutaneous nerve will be examined. Along with electrophysiological findings, shoulder range of motion (ROM), pain (VAS), muscle strength (MRC), and functional scores will also be recorded.\n\nThis study is expected to provide objective evidence regarding the effects of arthroscopic capsular release surgery on peripheral nerve function, thereby contributing new data on the safety of the surgical technique and enriching the currently limited literature on electromyographic evaluation in frozen shoulder surgery.",[29,27],[29,346,347,348,349,350,351],"360° Capsular Release","Shoulder Arthroscopy","Electromyography","Axillary Nerve","Musculocutaneous Nerve","Peripheral Nerve Function","2026-03-23",{"date":354,"type":42},"2026-03-27",{"date":356,"type":42},"2026-02-26",{"date":358,"type":21},"2027-03-14",{"name":360,"class":49},"Acibadem University",{"id":362,"slug":363,"hasResults":12,"nctId":364,"briefTitle":365,"officialTitle":366,"acronym":367,"eligibilityCriteria":368,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":369,"targetDuration":4,"studyType":22,"phases":370,"briefSummary":371,"conditions":372,"keywords":376,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":383,"lastUpdatePostDateStruct":384,"startDateStruct":386,"completionDateStruct":388,"leadSponsor":390,"locationsCount":50},"100622166","suprascapular-nerve-block-to-improve-tolerance-and-outcomes-of-shoulder-hydrodistension-in-adhesive-capsulitis-100622166","NCT07380087","Suprascapular Nerve Block to Improve Tolerance and Outcomes of Shoulder Hydrodistension in Adhesive Capsulitis","Efficacy of Suprascapular Nerve Block on the Tolerability and Effectiveness of Shoulder Hydrodistension in Patients With Adhesive Capsulitis: A Randomized Clinical Trial","SHINE","Inclusion Criteria\n\n* Adults aged 18 years or older\n* Clinical diagnosis of adhesive capsulitis of the shoulder\n* Persistent pain and functional limitation despite initial conservative treatment\n* Ability to understand study procedures\n* Ability to provide written informed consent\n\nExclusion Criteria\n\n* Known allergy or hypersensitivity to ropivacaine or methylprednisolone\n* Active infection (local or systemic)\n* Uncontrolled coagulopathy or ongoing therapeutic anticoagulation\n* Recent surgery of the affected shoulder\n* Neurological disease affecting the upper limb\n* Pregnancy",{"count":93,"type":21},[24],"Adhesive capsulitis (\"frozen shoulder\") causes significant pain and loss of shoulder mobility. Shoulder hydrodistension is an established treatment that can improve movement and reduce symptoms, but the procedure itself may be painful and difficult for some patients to tolerate.\n\nThis randomized clinical trial will evaluate whether performing a suprascapular nerve block with local anesthetic immediately before hydrodistension can reduce pain during the procedure, improve patient comfort, and potentially enhance clinical outcomes.\n\nParticipants will be randomly assigned to one of two groups:\n\nhydrodistension alone, or\n\nsuprascapular nerve block followed by hydrodistension.\n\nPain, shoulder mobility, functional ability, psychological measures, and quality of life will be assessed at baseline, 1 month, and 3 months after the procedure. The study aims to determine whether adding a suprascapular nerve block provides better tolerability and improved recovery for patients with adhesive capsulitis.",[29,373,374,27,99,375],"Adhesive Capsulitis of Unspecified Shoulder","Adhesive Capsulitis, Shoulder","Shoulder Stiffness",[377,378,99,379,380,381,382],"Shoulder Hydrodistension","Suprascapular Nerve Block","Shoulder Mobility","Randomized Clinical Trial","Pain Management","Rehabilitation","2026-01-26",{"date":385,"type":42},"2026-02-02",{"date":387,"type":21},"2026-03-01",{"date":389,"type":21},"2028-07-31",{"name":391,"class":49},"Universidade do Porto",{"id":393,"slug":394,"hasResults":12,"nctId":395,"briefTitle":396,"officialTitle":397,"acronym":398,"eligibilityCriteria":399,"healthyVolunteers":12,"sex":16,"minAge":59,"maxAge":248,"enrollmentInfo":400,"targetDuration":4,"studyType":22,"phases":401,"briefSummary":402,"conditions":403,"keywords":404,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":408,"lastUpdatePostDateStruct":409,"startDateStruct":411,"completionDateStruct":413,"leadSponsor":415,"locationsCount":50},"100617792","neural-mobilization-and-capsular-stretching-in-adhesive-capsulitis-100617792","NCT07323225","Neural Mobilization and Capsular Stretching in Adhesive Capsulitis","Effectiveness of Combined Neural Mobilization Techniques and Capsular Stretching Exercises in Patients With Adhesive Capsulitis.","RCT","Inclusion Criteria:\n\n* Patients from both gender (male \\&female) will be included if they would have second or third stage AC with their age between forty and seventy years\n* experiencing pain, capsular adhesions, and a reduction of greater than fifty percentage in passive ROM of the GH joint (external rotation, abduction, and internal rotation compared to the sound side\n* lasting for a minimum of three months. Patients with positive upper limb tension test-1 will be also included in this study\n\nExclusion Criteria:\n\n* they would have stroke,Parkinson's diseases that interfere with shoulder muscles activity\n* diabetes\n* traumatic shoulder conditions\n* glenohumeral osteoarthritis confirmed by x-ray\n* previous surgery, and manipulation of the affected GH joint under general anesthesia\n* Patients with passive elbow extension ROM",{"count":93,"type":21},[24],"Restriction of glenohumeral (GH) mobility in patients with adhesive capsulitis (AC) was known owing to capsular adhesion. There is a little evidence about the involvement of neural restriction in limiting range of motion (ROM) of the GH joint in patients with AC. Objectives: The purpose of this study is to investigate the combined effect of median nerve mobilization and capsular stretching on improving shoulder external rotation, abduction and internal rotation ROM among patients with AC. Methods Thirty patients will be randomly assigned into two equal groups : Group (A) will receive median nerve mobilization and capsular stretching while Group (B) will receive only capsular stretching (anterior, posterior and anteroinferior capsular stretching). Both groups will receive passive and self-assisted exercises. All patients in both groups will be evaluated pre and post treatment for GH external rotation, abduction and internal rotation ROM.",[29],[405,406,407],"Adhesive capsulitis","neural mobilization","capsular stretch","2025-12-28",{"date":410,"type":42},"2026-01-07",{"date":412,"type":21},"2026-01-01",{"date":414,"type":21},"2026-04-10",{"name":416,"class":49},"Prince Sattam Bin Abdulaziz University",{"id":418,"slug":419,"hasResults":12,"nctId":420,"briefTitle":421,"officialTitle":422,"acronym":4,"eligibilityCriteria":423,"healthyVolunteers":12,"sex":16,"minAge":59,"maxAge":18,"enrollmentInfo":424,"targetDuration":4,"studyType":22,"phases":426,"briefSummary":427,"conditions":428,"keywords":429,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":408,"lastUpdatePostDateStruct":432,"startDateStruct":434,"completionDateStruct":435,"leadSponsor":436,"locationsCount":50},"100519264","conservative-treatment-of-early-adhesive-capsulitis-100519264","NCT06041282","Conservative Treatment of Early Adhesive Capsulitis","A Multicentre Randomized Controlled Trial of Manipulation Under Anesthesia and Supervised Home Rehabilitation in the Treatment of Early Adhesive Capsulitis","Inclusion Criteria:\n\n* Patients in our hospital who need manual release of periarthritis of shoulder or home rehabilitation treatment;\n* Unilateral and primary periarthritis of shoulder\n* Age ≥40 years old and ≤80 years old, regardless of gender.\n* Forward flexion movement is more than 50% limited compared with the contralateral.\n* Duration of disease ≤3 months\n\nExclusion Criteria:\n\n* Patients with a previous history of shoulder joint surgery\n* Patients who did not complete the follow-up within the specified time\n* Patients with other shoulder diseases.\n* Patient with systemic immune disease.\n* Patients who have participated in clinical trials or are conducting other clinical trials within 3 months before screening\n* Patients with serious primary cardiovascular diseases, lung diseases, endocrine and metabolic diseases, or serious diseases affecting their survival, such as tumor or AIDS, are considered not suitable for admission.\n* Patients with serious liver diseases, kidney diseases, hematological diseases, such as kidney function (BUN, Cr) more than the upper limit of normal, liver function (ALT, AST, TBIL) more than 2 times the upper limit of normal.\n* Patients with viral hepatitis, infectious diseases, abnormal blood coagulation mechanism and other diseases that researchers consider inappropriate for surgery.\n* Pregnant or lactating women, or those planning to get pregnant during the test, with positive urine HCG test results before the test; Menstruating women should wait until their period is over before undergoing surgery.\n* Patients with severe neurological and mental diseases.\n* Suspected or true history of alcohol and drug abuse.",{"count":425,"type":21},300,[24],"A prospective, multicentre, randomized controlled study comparing the efficacy of conservative treatment for early adhesive capsulitis",[29],[430,431],"manipulation under anesthesia","supervised home rehabilitation",{"date":433,"type":42},"2026-01-02",{"date":412,"type":21},{"date":327,"type":21},{"name":437,"class":49},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"id":439,"slug":440,"hasResults":12,"nctId":441,"briefTitle":442,"officialTitle":442,"acronym":4,"eligibilityCriteria":443,"healthyVolunteers":12,"sex":16,"minAge":59,"maxAge":118,"enrollmentInfo":444,"targetDuration":4,"studyType":22,"phases":446,"briefSummary":447,"conditions":448,"keywords":449,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":450,"lastUpdatePostDateStruct":451,"startDateStruct":453,"completionDateStruct":455,"leadSponsor":457,"locationsCount":50},"100618182","additional-effects-of-thoracic-spine-mobilization-combined-with-glenohumeral-joint-mobilization-on-pain-range-of-motion-and-functional-disability-in-adhesive-capsulitis-100618182","NCT07328295","Additional Effects of Thoracic Spine Mobilization Combined With Glenohumeral Joint Mobilization on Pain, Range of Motion, and Functional Disability in Adhesive Capsulitis","Inclusion Criteria:\n\n* • Both male and female patients with a primary complaint of unilateral or bilateral shoulder pain\n\n  * Pain has persisted for at least 3 to 4 months\n  * Decreased shoulder ROM observed, including external shoulder rotation, abduction, internal rotation, and flexion\n  * Age range between 40 to 65 years\n  * Diagnosed with stage 2nd or 3rd of the disease.\n\nExclusion Criteria:\n\n* • Patients if they had any shoulder pain resulting from systematic disease such as Rheumatoid Arthritis (morning stiffness \\> 1 hour, multiple small joints pain\u002Fswelling) Infection, Tumors, and conditions like myelopathy (Hoffman's sign).\n\n  * Recent shoulder joint fracture\u002F trauma.\n  * Thoracic Outlet Syndrome (Roos test).\n  * The presence of Cervical radiculopathy (Spurling's test)",{"count":445,"type":21},34,[24],"Adhesive capsulitis is a debilitating shoulder condition characterized by pain, restricted range of motion (ROM), and significant functional limitations. Conventional treatment primarily targets the glenohumeral joint, often neglecting the role of regional interdependence, particularly the thoracic spine's influence on shoulder mobility. Emerging evidence suggests that thoracic spine mobility plays a crucial role in optimizing shoulder mechanics, yet its therapeutic application in adhesive capsulitis remains underexplored. This study aims to investigate the additional effects of thoracic spine mobilization combined with glenohumeral joint mobilization, providing a more comprehensive rehabilitation approach to enhance pain relief, ROM, and functional outcomes.\n\nA randomized controlled trial (RCT) will be conducted over one year at the Rehabilitation Department of Fauji Foundation Hospital (FFH) after obtaining ethical approval. Participants diagnosed with adhesive capsulitis will be selected through non-probability purposive sampling based on predefined inclusion and exclusion criteria. Subjects will be randomly assigned to either the experimental group receiving thoracic spine mobilization alongside glenohumeral joint mobilization or the control group receiving glenohumeral joint mobilization alone. Randomization will be conducted using the coin toss method and block randomization to ensure balanced subject distribution.\n\nOutcome measures include the Numeric Pain Rating Scale (NPRS) for pain assessment, the Shoulder Pain and Disability Index (SPADI) for functional disability evaluation, and a goniometer for ROM measurement. Baseline and post-treatment scores will be statistically analyzed using SPSS to determine intervention effectiveness. By integrating thoracic spine mobilization into standard treatment, this study seeks to refine clinical rehabilitation protocols, improve functional recovery, and enhance patient outcomes. Findings may contribute to evidence-based practice, supporting the inclusion of thoracic spine mobilization in treatment guidelines for adhesive capsulitis.",[29],[35],"2025-12-26",{"date":452,"type":42},"2026-01-09",{"date":454,"type":42},"2025-01-15",{"date":456,"type":21},"2026-01-15",{"name":458,"class":49},"Foundation University Islamabad",{"id":460,"slug":461,"hasResults":12,"nctId":462,"briefTitle":463,"officialTitle":464,"acronym":4,"eligibilityCriteria":465,"healthyVolunteers":12,"sex":16,"minAge":59,"maxAge":248,"enrollmentInfo":466,"targetDuration":4,"studyType":22,"phases":468,"briefSummary":469,"conditions":470,"keywords":471,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":476,"lastUpdatePostDateStruct":477,"startDateStruct":478,"completionDateStruct":480,"leadSponsor":482,"locationsCount":4},"100614701","effects-of-pectoralis-minor-exercises-on-shoulder-pain-scapular-dyskinesis-and-thoracic-expansion-in-adhesive-capsulitis-patients-100614701","NCT07283016","Effects of Pectoralis Minor Exercises on Shoulder Pain, Scapular Dyskinesis and Thoracic Expansion in Adhesive Capsulitis Patients","Effects of Pectoralis Minor Stretching and Strengthening Exercises on Shoulder Pain, Scapular Dyskinesis and Thoracic Expansion Among Patients With Adhesive Capsulitis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age: 40 - 70 years\n* Gender: Both Male \\& Female\n* Clinical diagnosis of adhesive capsulitis (Thawing stage).\n* Reduced thoracic expansion.\n* Scapular dyskinesis\n\nExclusion Criteria:\n\n* Presence of rotator cuff tear, labral tears, or glenohumeral arthritis confirmed through imaging\n* Post-stroke hemiparesis,\n* Winged scapula due to lesions of long thoracic nerve or spinal accessory nerve.\n* Rotator cuff repair\n* Capsular release\n* Arthroplasty",{"count":467,"type":21},70,[24],"The goal of the current study is to evaluate the effects of pectoralis minor stretching and strengthening with mobility and stability exercises in patients aged 40-70 years with adhesive capsulitis. The main questions it aims to answer are:\n\nDoes the combination of pectoralis minor stretching and strengthening with mobility and stability exercises significantly reduce shoulder pain compared to mobility and stability exercises only? Does the combination of pectoralis minor stretching and strengthening with mobility and stability exercises improve scapular dyskinesis (scapular movement patterns) and thoracic expansion more effectively than mobility and stability exercises? Participants will be assigned to either an experimental group receiving pectoralis minor stretching and strengthening exercises with mobility and stability exercises or a control group receiving mobility and stability exercises only, and will complete standardized assessments of shoulder pain, scapular dyskinesis (scapular movement patterns) and thoracic expansion before and after the intervention.",[29],[472,473,99,474,475],"Strengthening exercises","Scapular dyskinesis","Thoracic Expansion","Pectoralis minor","2025-12-11",{"date":152,"type":42},{"date":479,"type":21},"2025-12",{"date":481,"type":21},"2026-03",{"name":483,"class":49},"Lahore University of Biological and Applied Sciences",{"id":485,"slug":486,"hasResults":12,"nctId":487,"briefTitle":488,"officialTitle":489,"acronym":4,"eligibilityCriteria":490,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":118,"enrollmentInfo":491,"targetDuration":4,"studyType":22,"phases":493,"briefSummary":494,"conditions":495,"keywords":499,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":500,"lastUpdatePostDateStruct":501,"startDateStruct":503,"completionDateStruct":505,"leadSponsor":507,"locationsCount":50},"100611103","the-effects-of-immersive-virtual-reality-in-patients-with-grade-1-2-adhesive-capsulitis-100611103","NCT07236229","The Effects of Immersive Virtual Reality in Patients With Grade 1-2 Adhesive Capsulitis","The Effects of Immersive Virtual Reality-Based Exercise Therapy on Pain, Functionality, Sleep, and Cognitive Functions in Patients With Grade 1-2 Adhesive Capsulitis","Inclusion Criteria:\n\n* Diagnosed with adhesive capsulitis by a doctor\n* Classified as Grade 1-2 adhesive capsulitis\n* Receiving physiotherapy for adhesive capsulitis for the first time\n* Aged between 18 and 64 years\n* Suitable for using a VR headset\n\nExclusion Criteria:\n\n* Previous history of physiotherapy\n* Presence of any mental disorder\n* Recent surgery or any shoulder condition (e.g., fractures around the shoulder region) that contraindicates shoulder mobilization\n* History of receiving injections",{"count":492,"type":21},36,[24],"Adhesive capsulitis (frozen shoulder) is a complex condition characterized by inflammation, fibrosis, and restriction of movement in the shoulder capsule, significantly limiting an individual's participation in daily living activities. It is most commonly observed in individuals aged between 40 and 60 years, and its treatment frequently involves approaches such as manual therapy, exercise, corticosteroid injections, and electrotherapy. However, these conventional methods may be limited by factors such as lack of motivation, pain-related avoidance behavior, and poor treatment adherence.\n\nToday, immersive virtual reality technologies introduce a new dimension to rehabilitation by gamifying exercise, providing sensory feedback, and enabling graded exposure through mechanisms such as distraction and engagement. They also enhance motivation and compliance with exercise programs. Studies in the literature have reported that virtual reality-based exercise is an effective method for reducing pain levels in patients diagnosed with frozen shoulder.\n\nHowever, only a limited number of studies have specifically examined the effects of immersive virtual reality in patients with adhesive capsulitis. To date, no study has investigated the impact of immersive virtual reality interventions on sleep and cognitive functions in these patients. Furthermore, the combined effect of patient education, home exercise programs, and immersive virtual reality therapy has not yet been explored. For these reasons, the present study aims to investigate the effects of immersive virtual reality-based exercise therapy on pain, functionality, sleep, and cognitive functions in patients with Grade 1-2 adhesive capsulitis.",[29,496,497,296,498],"Virtual Reality","Sleep","Cognition",[29,496,497,296,498],"2025-11-27",{"date":502,"type":42},"2025-12-01",{"date":504,"type":21},"2025-11-28",{"date":506,"type":21},"2026-02-27",{"name":508,"class":49},"Bahçeşehir University",{"id":510,"slug":511,"hasResults":12,"nctId":512,"briefTitle":513,"officialTitle":514,"acronym":4,"eligibilityCriteria":515,"healthyVolunteers":12,"sex":16,"minAge":59,"maxAge":60,"enrollmentInfo":516,"targetDuration":4,"studyType":22,"phases":517,"briefSummary":518,"conditions":519,"keywords":520,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":525,"startDateStruct":527,"completionDateStruct":529,"leadSponsor":531,"locationsCount":50},"100608623","additional-effects-of-niel-asher-technique-on-patients-with-adhesive-capsulitis-100608623","NCT07203963","Additional Effects of Niel-asher Technique on Patients With Adhesive Capsulitis","Additional Effects of Niel Asher Technique Along With Sleeper Stretch on Posterior Capsule in Patients With Adhesive Capsulitis.","Inclusion Criteria:\n\n* Age 40-60 years\n* Both Genders: Male and Female\n* Patient falls under diagnostic criteria for adhesive capsulitis which is Painful and limited active and passive glenohumeral ROM in capsular pattern (external rotation\\> abduction\\> internal rotation)\n* Patient diagnosed with adhesive capsulitis by orthopedic or general physician\n* Patient with phase two and three of adhesive capsulitis based on duration of symptoms\n* Patients of adhesive capsulitis with presence of trigger points in rotator cuff muscles and deltoid muscle (trigger points present in at least 1 or 2 of these muscles) based on simon and travell's criteria of trigger points diagnosis.\n\nExclusion Criteria:\n\n* Spinal Injuries and any other co- morbidity\n* Any surgery, infection, trauma, pregnancy, fracture and fall\n* Patient with intra articular steroidal therapy with in last 6 months\n* Patient unwilling to comply follow up schedule\n* Patient involvement in another intervention study\n* Malignancy\n* Patient with thyroid disorders and RA and Glenohumeral OA\n* History of previous surgery or manipulation under anesthesia of affected shoulder\n* Patient with duration of symptoms of less than three months",{"count":492,"type":21},[24],"The aim of this randomized controlled trial is to find the additional effects of Niel-Asher technique along with sleeper stretch and conventional physical therapy on pain, shoulder ranges of motion and functional disability in patients with Adhesive capsulitis",[29],[521,522,523],"Niel-Asher Technique (NAT)","Sleeper stretch","trigger points","2025-11-18",{"date":526,"type":42},"2025-11-24",{"date":528,"type":42},"2025-10-25",{"date":530,"type":21},"2026-09-20",{"name":109,"class":49},{"id":533,"slug":534,"hasResults":12,"nctId":535,"briefTitle":536,"officialTitle":536,"acronym":4,"eligibilityCriteria":537,"healthyVolunteers":140,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":538,"targetDuration":4,"studyType":22,"phases":540,"briefSummary":542,"conditions":543,"keywords":545,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":551,"lastUpdatePostDateStruct":552,"startDateStruct":554,"completionDateStruct":556,"leadSponsor":558,"locationsCount":50},"100230929","phase-4-adhesive-capsulitis-prospective-analysis-of-efficacy-and-financial-impact-for-use-of-physical-therapy-in-treatment-100230929","NCT02283996","Adhesive Capsulitis: Prospective Analysis of Efficacy and Financial Impact for Use of Physical Therapy in Treatment","Inclusion Criteria:\n\n* Patient must be 18 years or older\n* Must meet the following definition for adhesive capsulitis as defined by the American Academy of Orthopedic Surgeons: Self-limiting condition resulting from any inflammatory process about the shoulder in which capsular scar tissue is produced, resulting in pain and limited range of motion; also called frozen shoulder\n* Must be amenable to randomization into either cohort\n\nExclusion Criteria:\n\n* Non-English speaking patients\n* Pregnant women (women of childbearing potential will be advised to undergo regular pregnancy testing)\n* Patients who had previously undergone operative therapy for the condition",{"count":539,"type":21},260,[541],"PHASE4","The purpose of this study is to identify individuals 18 or older who have diagnostic presentation of adhesive capsulitis and randomize them into two arms, distinguished by use of physical therapy and steroid injections compared with steroid injections followed by watchful waiting. This prospective study will be used to determine whether there is a significant impact on patient outcome and whether the additional financial burden is justified. There are no experimental interventions for this study. The use of physical therapy, oral and parenteral corticosteroids, and watchful waiting are offered following the standard of care for adhesive capsulitis. Our hypothesis is that patients will not have a significant difference in outcome between the two study arms. One group will undergo regular physical therapy with corticosteroid injections (Arm 1) and the other will have steroid injections during the inflammatory phase only and then be regularly observed (Arm 2). We also hypothesize there will be a significant financial burden associated with the PT arm that is not justified with the possibility of increased symptom reports in that arm.",[29,27,544],"Shoulder Frozen",[29,27,544,69,546,547,548,549,550],"Corticosteroid Injections","Hydrodilation, Hydro-dilation","Watchful Waiting","Prospective","Glenohumeral Ligament","2025-10-24",{"date":553,"type":42},"2025-10-27",{"date":555,"type":42},"2014-11",{"date":557,"type":21},"2027-12",{"name":559,"class":49},"Massachusetts General Hospital",{"id":561,"slug":562,"hasResults":12,"nctId":563,"briefTitle":564,"officialTitle":565,"acronym":4,"eligibilityCriteria":566,"healthyVolunteers":12,"sex":16,"minAge":247,"maxAge":118,"enrollmentInfo":567,"targetDuration":4,"studyType":22,"phases":568,"briefSummary":569,"conditions":570,"keywords":574,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":580,"startDateStruct":582,"completionDateStruct":584,"leadSponsor":586,"locationsCount":50},"100605543","the-effect-of-fascial-treatment-in-patients-with-adhesive-capsulitis-100605543","NCT07163884","The Effect of Fascial Treatment in Patients With Adhesive Capsulitis","Adheziv kapsülit tanılı Hastalarda Fasyal Tedavinin ağrı, Normal Eklem Hareket açıklığı, Propriosepsiyon ve Fasya Mimarisine Etkisinin araştırılması","Inclusion Criteria:\n\n* Patients diagnosed with adhesive capsulitis by a specialist,\n* Patients between the ages of 35 and 60,\n* Those not diagnosed with cervical disc herniation that could cause other shoulder pathologies,\n* Those who have not participated in an upper extremity-related physiotherapy program within the last 6 months,\n* Individuals who volunteer to participate in the study,\n\nExclusion Criteria:\n\n* Individuals who have undergone shoulder surgery consistent with any pathology,\n* Individuals with a neurological history,\n* Individuals diagnosed with diabetes mellitus (DM)",{"count":492,"type":21},[24],"Our study is unique in that it utilizes a self-designed fascial mobilization protocol and ultrasonographic evaluation for adhesive capsulitis. Therefore, the aim of our study is to investigate the effects of fascial therapy on pain, normal joint range of motion, proprioception, and fascial architecture in patients diagnosed with adhesive capsulitis.",[29,571,572,573],"Ultrasonography","Fascia","Treatment (ProudMe)",[575,576,577,578,579],"adhezsiv capsulitis","pain","range of motion","proprioception","fascia architecture",{"date":581,"type":42},"2025-09-09",{"date":583,"type":21},"2025-09-15",{"date":585,"type":21},"2025-11-15",{"name":587,"class":49},"Hasan Kalyoncu University",{"id":589,"slug":590,"hasResults":12,"nctId":591,"briefTitle":592,"officialTitle":593,"acronym":4,"eligibilityCriteria":594,"healthyVolunteers":12,"sex":16,"minAge":247,"maxAge":118,"enrollmentInfo":595,"targetDuration":4,"studyType":22,"phases":597,"briefSummary":598,"conditions":599,"keywords":600,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":604,"lastUpdatePostDateStruct":605,"startDateStruct":607,"completionDateStruct":608,"leadSponsor":609,"locationsCount":50},"100605110","effects-of-exercise-on-adhesive-capsulitis-100605110","NCT07158255","Effects of Exercise on Adhesive Capsulitis","Effect of Exercise Training on Pain, Range of Motion, Functionality and Shoulder Architecture in Patients With Adhesive Capsulitis","Inclusion Criteria:\n\n* Diagnosed with adhesive capsulitis by a physician,\n* Between the ages of 35-60,\n* Not diagnosed with cervical disc herniation that could cause other shoulder pathologies,\n* Not participating in an upper extremity-related physiotherapy program within the last 6 months,\n* Volunteering individuals to participate in the study\n\nExclusion Criteria:\n\n* Individuals who have undergone shoulder surgery consistent with any pathology,\n* Individuals with a neurological history,\n* Individuals diagnosed with diabetes mellitus (DM)",{"count":596,"type":21},32,[24],"Our study aims to investigate the effects of exercise training on pain, range of motion, functionality and shoulder architecture in patients with adhesive capsulitis.",[29,68,571],[575,576,577,601,602,603],"functionality","shoulder architecture","exercise","2025-08-28",{"date":606,"type":42},"2025-09-05",{"date":606,"type":21},{"date":585,"type":21},{"name":587,"class":49},{"id":611,"slug":612,"hasResults":12,"nctId":613,"briefTitle":614,"officialTitle":615,"acronym":616,"eligibilityCriteria":617,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":618,"targetDuration":4,"studyType":22,"phases":620,"briefSummary":621,"conditions":622,"keywords":623,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":625,"lastUpdatePostDateStruct":626,"startDateStruct":628,"completionDateStruct":630,"leadSponsor":631,"locationsCount":50},"100603245","the-impact-of-perineural-injection-therapy-for-adhesive-capsulitis-100603245","NCT07134010","The Impact of Perineural Injection Therapy for Adhesive Capsulitis.","The Impact of Perineural Injection Therapy for Adhesive Capsulitis at a Single Centre University Hospital in Selangor: A Pilot Study","PIT; AC","Inclusion Criteria:\n\n1. Age 18 and above.\n2. Diagnosed with primary adhesive capsulitis by a specialist.\n3. Limitation of range of motion ≥ 50% relative to the normal side or normal reference (in patient with bilateral adhesive capsulitis) in three or more movement directions (i.e., external rotation, abduction, forward flexion, and internal rotation).\n4. Chronic adhesive capsulitis shoulder pain lasting for at least 3 months.\n5. Pain score of at least 4\u002F10 on the Numerical Rating Scale (NRS) during movement, indicating at least moderate pain severity.\n6. Consented to the study.\n\nExclusion Criteria:\n\n1. Received any shoulder pain injection within the past 6 weeks or surgical intervention such manipulation under anesthesia, arthroscopic capsular release, or open surgery for capsular release.\n2. Diagnosed with other shoulder pathology such as neurologic deficits affecting shoulder function, tumour, rotator cuff injury or fracture.\n3. Has history of allergy to dextrose solution.\n4. Patients receiving steroidsimmunosuppressants, psychotropic medication, or other medications that may affect, the clinical outcomes\n5. Patients with haemorrhagic disease, taking anticoagulant drugs, or patients with severe diabetes mellitus having an increased risk of infection (HBA1c \\>8%)\n6. Do not understand Malay or English language.\n7. Unable to follow a 3 steps command.",{"count":619,"type":21},24,[24],"The goal of this clinical trial is to learn if Perineural Injection Therapy (PIT) works to treat adhesive capsulitis (frozen shoulder) in adults. It will also learn about the safety of PIT.\n\nThe main questions it aims to answer are:\n\nDoes PIT reduce shoulder pain and improve shoulder range of motion more effectively than conventional therapy alone?\n\nWhat side effects or medical problems do participants experience when receiving PIT?\n\nResearchers will compare PIT to conventional therapy to see if PIT works better to treat adhesive capsulitis.\n\nParticipants will:\n\nReceive either:\n\nPIT once weekly for 6 weeks plus physiotherapy and oral analgesics (excluding NSAIDs), or\n\nConventional therapy only (physiotherapy and analgesics including NSAIDs)\n\nAttend scheduled follow-up visits at Week 6, 1 month, and 3 months after treatment\n\nPerform daily home-based shoulder exercises and record their analgesic use and any side effects in a patient diary",[29],[624],"Perineural injection therapy in treating Adhesive Capsulitis","2025-08-27",{"date":627,"type":42},"2025-09-04",{"date":629,"type":42},"2025-06-03",{"date":179,"type":21},{"name":632,"class":49},"Universiti Teknologi Mara",{"id":634,"slug":635,"hasResults":12,"nctId":636,"briefTitle":637,"officialTitle":638,"acronym":4,"eligibilityCriteria":639,"healthyVolunteers":12,"sex":16,"minAge":247,"maxAge":118,"enrollmentInfo":640,"targetDuration":4,"studyType":22,"phases":641,"briefSummary":642,"conditions":643,"keywords":644,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":649,"lastUpdatePostDateStruct":650,"startDateStruct":652,"completionDateStruct":654,"leadSponsor":656,"locationsCount":50},"100599097","comparison-of-niel-asher-and-spencer-techniques-in-frozen-shoulder-patients-100599097","NCT07080060","Comparison of Niel-Asher and Spencer Techniques in Frozen Shoulder Patients","Effects of Niel-Asher Technique Versus Spencer Technique Along With Conventional Therapy on Pain, Range of Motion, and Functional Status in Frozen Shoulder Patients","Inclusion Criteria:\n\n* Age group between 35-65 years diagnosed with primary Adhesive Capsulitis.\n* Both gender male and female.\n* Both Active and passive Range of Motion is limited.\n* Stage II Frozen Shoulder patients (Freezing Stage,3-9 months).\n* More than 50% of range of motion is limited in Flexion, Abduction and External rotation as compared to unaffected side.\n* Pain reported on VAS score \\\u003C7\u002F10 in shoulder region.\n* Patients agree to sign written consent form.\n\nExclusion Criteria:\n\n* Patients with systemic illness:\n* Diabetes Mellitus, Thyroid disorders.\n* Rheumatoid Arthritis, Malignancy.\n* Patients with mechanical injuries like:\n* Rotator Cuff injury, Ligamentous Injuries.23\n* Previous Surgery or Manipulation under Anesthesia.\n* Patients with Stage I, III, IV of Frozen Shoulder.\n* Patient reported with VAS score \\>7\u002F10 in shoulder region.",{"count":291,"type":21},[24],"This study aims to compare the effectiveness of two manual therapy techniques-Niel-Asher Technique and Spencer Technique-when combined with conventional physiotherapy in treating patients with frozen shoulder (adhesive capsulitis). Frozen shoulder is a painful condition that limits movement and function of the shoulder joint. The study will include 44 adults aged 35 to 65 years who have been diagnosed with stage II frozen shoulder. Participants will be randomly assigned to one of two groups. Both groups will receive standard physiotherapy, including heat therapy, TENS, and stretching exercises. In addition, one group will receive the Niel-Asher Technique, while the other group will receive the Spencer Technique. Pain, range of motion, and shoulder function will be measured before and after a 4-week treatment period using validated tools such as the Visual Analogue Scale (VAS), a goniometer, and the Shoulder Pain and Disability Index (SPADI). The goal is to determine which manual therapy technique is more effective in improving symptoms and function in patients with frozen shoulder.",[27,29],[645,646,647,296,648],"Manual Therapy","Niel-Asher Technique","Spencer Technique","Range of motion","2025-07-14",{"date":651,"type":42},"2025-07-23",{"date":653,"type":21},"2025-07",{"date":655,"type":21},"2025-11-30",{"name":109,"class":49}]