[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"adult-patients-with-septic-shock-admitted-in-intensive-care-unit\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:adult-patients-with-septic-shock-admitted-in-intensive-care-unit":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100614003","remote-ischemic-postconditioning-in-septic-shock-100614003",false,"NCT07273942","Remote Ischemic Postconditioning in Septic Shock","RIPOST-sepsis","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Hospitalized in intensive care unit for less than 24 hours\n* Septic shock (Sepsis-3 definition) evolving for less than 18 hours\n* Preliminary written informed consent obtained from the patient or his\u002Fher close relative, or use of the emergency procedure in accordance with local regulations\n\nExclusion Criteria:\n\n* Contraindication of the use of a brachial pressure cuff on both arms\n* Cardiac arrest\n* Pregnancy or breast feeding\n* Participation in another interventional study\n* Lack of French national health insurance coverage\n* Patient with any legal protection measure","ALL","18 Years",{"count":19,"type":20},720,"ESTIMATED","INTERVENTIONAL",[23],"NA","Septic shock is a leading cause of death worldwide despite intensive research efforts. Only a few interventions have been proven to be effective in improving patient-centered outcomes. Recent clinical trials have reported the safety and efficacy of remote ischemic postconditioning (RIPOST) in a variety of pathologies, including myocardial infarction, cardiac surgery, and stroke. While RIPOST was mainly tested in pathologies with low mortality rates, several follow-up studies of large randomized clinical trials in acute myocardial infarction and in patients undergoing coronary artery bypass surgery have reported significant decreases (\\> 50%) in long-term mortality. Experimental studies and proof-of-concept clinical trials have also suggested the potential benefits of RIPOST on mortality in sepsis and septic shock. The present protocol aims to test whether this non-invasive, widely available, inexpensive, and innovative intervention can improve survival in septic shock.",[26],"Adult Patients With Septic Shock Admitted in Intensive Care Unit",[28,29,30,31,32],"Septic shock","Remote conditioning","Ischemic conditioning","Ischemia-reperfusion","Intensive care unit","NOT_YET_RECRUITING","2026-10-08",{"date":36,"type":37},"2026-10-09","ACTUAL",{"date":39,"type":20},"2027-01",{"date":41,"type":20},"2029-04",{"name":43,"class":44},"Hospices Civils de Lyon","OTHER",23]