[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"airway-management\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:airway-management":24},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,41,0,25,[9,43,68,95,131,154,186,217,237,267,298,325,354,377,401,430,458,480,507,536,560,586,612,634,664],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100652560","the-effect-of-ultrasonographic-airway-measurements-and-anatomical-differences-on-laryngeal-mask-placement-in-young-and-older-adults-a-prospective-observational-study-100652560",false,"NCT07776847","The Effect of Ultrasonographic Airway Measurements and Anatomical Differences on Laryngeal Mask Placement in Young and Older Adults: A Prospective Observational Study","Inclusion Criteria:\n\n* Patient or legally appropriate representative\u002Frelative accepts participation as applicable.\n* Surgery suitable for LMA placement.\n* Age 18-40 years or \\>65 years.\n\nExclusion Criteria:\n\n* Pregnancy\n* Age \\\u003C18 years\n* History of upper airway surgery\n* Gastroesophageal reflux disease, ulcer, or gastrointestinal bleeding history\n* Inadequate fasting duration\n* Emergency surgery\n* Requirement for nasogastric tube placement\n* Unstable teeth\n* Mouth opening \\\u003C3 cm\n* Recent pulmonary infection\n* Recent upper airway infection\n* Pulmonary disease associated with increased airway pressures (cystic fibrosis, COPD, interstitial lung disease)\n* Restricted cervical movement \u002F inability to achieve required extension\n* Ultrasound gel allergy\n* Refusal to participate","ALL","18 Years",{"count":19,"type":20},188,"ESTIMATED","OBSERVATIONAL","This prospective observational study aims to compare ultrasonographic upper-airway measurements and age-related anatomical differences between young adults (18-40 years) and older adults (\\>65 years), and to evaluate their effects on laryngeal mask airway (LMA) placement success and position accuracy. Preoperative airway ultrasonography measurements will be assessed, followed by evaluation of LMA placement, ventilation efficacy, insertion attempts, placement time, and complications. Ultrasonography will also be used to assess LMA position after placement, with confirmation by leak testing and fiberoptic evaluation. Preoperative and postoperative gastric volume will additionally be assessed.",[24,25],"Airway Management","Laryngeal Mask Airway Insertion Skill",[27,28,29],"Laryngeal mask airway","airway ultrasonography","geriatrics","RECRUITING","2026-08-17",{"date":33,"type":34},"2026-08-20","ACTUAL",{"date":36,"type":34},"2025-07-01",{"date":38,"type":20},"2027-08-30",{"name":40,"class":41},"Duzce University","OTHER",1,{"id":44,"slug":45,"hasResults":12,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":52,"conditions":53,"keywords":54,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":42},"100651785","artificial-intelligence-assisted-ultrasound-assessment-of-laryngeal-mask-airway-placement-100651785","NCT07766382","Artificial Intelligence-Assisted Ultrasound Assessment of Laryngeal Mask Airway Placement","Artificial Intelligence-Assisted Ultrasound Confirmation of Laryngeal Mask Airway Placement Using Fiberoptic Assessment as the Reference Standard: A Prospective Diagnostic Accuracy Study","Inclusion Criteria:\n\n* Adults undergoing elective surgery under general anesthesia in whom LMA use is clinically planned; ASA physical status I-III; ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Emergency surgery; pregnancy; anticipated difficult airway; major upper airway or neck anatomical abnormality or previous major neck surgery; clinically significant aspiration risk or contraindication to LMA use; inability to obtain adequate ultrasound images or fiberoptic assessment.",{"count":51,"type":20},200,"This prospective observational study aims to develop and evaluate artificial intelligence-based models for the assessment of laryngeal mask airway (LMA) placement in adult patients undergoing elective surgery under general anesthesia. Following LMA insertion, standardized airway ultrasound images will be obtained and fiberoptic assessment will be performed as the anatomical reference standard. Fiberoptic findings will be classified as optimal (Brimacombe grades 3-4) or suboptimal (grades 1-2). Clinical and quantitative airway ultrasound variables will also be recorded. The predictive performance of tabular, image-only, and multimodal artificial intelligence models will be evaluated for identifying optimal versus suboptimal LMA placement.",[24],[55,56,57,58,59],"Laryngeal Mask Airway","Supraglottic Airway","Airway Ultrasonography","Artificial Intelligence","Machine Learning","2026-08-11",{"date":62,"type":34},"2026-08-14",{"date":64,"type":34},"2026-08-10",{"date":66,"type":20},"2027-05-15",{"name":40,"class":41},{"id":69,"slug":70,"hasResults":12,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":76,"enrollmentInfo":77,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":79,"conditions":80,"keywords":81,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":94},"100620283","videolaryngoscopic-difficult-ntubation-and-glottic-view-score-a-multicentre-prospective-study-100620283","NCT07355608","Videolaryngoscopic Difficult ıntubation and Glottic View Score: A Multicentre Prospective Study","Prediction of Difficult Videolaryngoscopic Intubation and Development of a Dedicated Glottic View Score: A Multicentre Prospective Study","VIDIGLOV","Inclusion Criteria:\n\n* Adults\n* Both with normal or predicted difficult airways\n* Undergoing orotracheal intubation with a videolarygoscope\n\nExclusion Criteria:\n\n* Rapid sequence intubation\n* Double lumen tube intubation","100 Years",{"count":78,"type":20},4977,"Background:\n\nVideolaryngoscopy has improved glottic visualization and facilitated tracheal intubation. However, difficulties-including failed intubation-still occur. At present, no prospectively derived classification system exists to assess the difficulty of videolaryngoscopic (VL) intubation across both normal and anticipated difficult airways. Additionally, current glottic view grading systems, designed for direct laryngoscopy, may not adequately capture the specific challenges of VL intubation.\n\nObjectives:\n\nThis study aims to:\n\n1. Develop a predictive model for difficult VL intubation in surgical patients with both normal and anticipated difficult airways.\n2. Create a glottic view scoring system specifically tailored to videolaryngoscopy.\n3. Compare the predictive accuracy of the new scoring system with existing laryngeal view grades in forecasting difficult VL intubation.",[24],[82,83,84],"Airway management","Videolaryngoscope","Difficult airway","NOT_YET_RECRUITING","2026-08-09",{"date":60,"type":34},{"date":89,"type":20},"2026-10-01",{"date":91,"type":20},"2027-02-01",{"name":93,"class":41},"Diskapi Teaching and Research Hospital",2,{"id":96,"slug":97,"hasResults":12,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":103,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":113,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":126,"leadSponsor":128,"locationsCount":42},"100650350","novel-integrated-tube-bougie-prototype-for-endotracheal-intubation-in-airway-simulation-100650350","NCT07747922","Novel Integrated Tube-Bougie Prototype for Endotracheal Intubation in Airway Simulation","A Prospective Randomized Crossover Simulation Study Comparing an Integrated Tube-Bougie Prototype With Standard Stilet-Assisted and Gum Elastic Bougie Assisted Endotracheal Intubation","ITBP","Inclusion Criteria:\n\n* Professional Status: Being an Emergency Medicine Resident actively undergoing specialty training at the University of Health Sciences, Kocaeli City Hospital, Department of Emergency Medicine.\n* Voluntary Participation: Voluntarily agreeing to participate in the study and providing written informed consent prior to enrollment.\n* Postgraduate year (PGY) 1-4 residents.\n* Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n* Refusal to Participate: Declining to participate or refusing to provide written informed consent.\n* Physical or Neurological Limitations: Having any pre-existing physical, motor, or neurological impairment that could interfere with manual dexterity, procedural performance, or airway management simulation (e.g., hand injuries, tremors, etc.).\n* Inability to complete all study procedures.",true,{"count":105,"type":20},40,"INTERVENTIONAL",[108],"NA","Endotracheal intubation is a critical airway management procedure that frequently requires adjunctive devices, such as stylets or elastic bougies, to facilitate successful tube placement. Although videolaryngoscopy has become increasingly common, access to videolaryngoscopes remains limited in certain clinical settings, particularly in prehospital and resource-constrained environments. Consequently, stylets and bougies continue to play an essential role in airway management. To address this need, we developed a novel integrated tube-bougie prototype that combines the guidance function of an elastic bougie with an endotracheal tube into a single device.\n\nThis prospective, randomized, crossover simulation study is designed to compare the performance of the integrated tube-bougie prototype with conventional stylet-assisted and elastic bougie-assisted endotracheal intubation. Emergency medicine residents will perform intubations using all three techniques in both normal and difficult airway simulation scenarios according to a randomized crossover sequence.\n\nThe primary outcome is the time to successful endotracheal intubation. Secondary outcomes include first-attempt intubation success, perceived procedural difficulty assessed using a visual analog scale (VAS), incidence of esophageal intubation, dental trauma, and evaluation of the learning curve using cumulative sum (CUSUM) analysis.\n\nThe findings could contribute to the development of alternative airway assistive equipment for emergency airway management and training.",[24,111,112],"Endotracheal Intubation","Difficult Airway",[112,111,24,114,115,116,117,118,119,120,121],"Emergency Medicine","Simulation","Manikin","Bougie","Gum Elastic Bougie","Stylet","EPATS","Medical Education","2026-07-31",{"date":124,"type":34},"2026-08-05",{"date":64,"type":20},{"date":127,"type":20},"2026-08-30",{"name":129,"class":130},"Huseyin Cahit Halhalli, MD","OTHER_GOV",{"id":132,"slug":133,"hasResults":12,"nctId":134,"briefTitle":135,"officialTitle":136,"acronym":4,"eligibilityCriteria":137,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":138,"targetDuration":4,"studyType":106,"phases":140,"briefSummary":141,"conditions":142,"keywords":4,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":4},"100648512","comparison-of-high-flow-nasal-cannula-and-tight-face-mask-for-maintaining-oxygenation-during-rapid-sequence-induction-100648512","NCT07723430","Comparison of High-Flow Nasal Cannula and Tight Face Mask for Maintaining Oxygenation During Rapid Sequence Induction","Comparison of the Effectiveness of High-Flow Oxygen Cannula Versus Tight Face Mask in Maintaining Oxygenation During Rapid Sequence Induction","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Patients requiring rapid sequence induction (RSI) for endotracheal intubation in the operating room, emergency department, or intensive care unit.\n* Patients in whom both high-flow nasal cannula (HFNC) and tight face mask preoxygenation are technically feasible.\n* Patients (or their legally authorized representatives, when applicable) able to provide written informed consent.\n\nExclusion Criteria:\n\n* Patients requiring immediate crash intubation without sufficient time for preoxygenation.\n* Patients with facial deformities, upper airway obstruction, or other conditions preventing the use of either HFNC or a tight face mask.\n* Known contraindications or hypersensitivity to medications used for rapid sequence induction.\n* Pregnant women.\n* Patients younger than 18 years of age.\n* Patients with do-not-intubate (DNI) orders.\n* Patients already intubated or mechanically ventilated before enrollment.\n* Patients who underwent endotracheal intubation within the previous 24 hours.",{"count":139,"type":20},290,[108],"This prospective randomized controlled trial aims to compare the effectiveness of High-Flow Nasal Cannula (HFNC) versus Tight Face Mask (TFM) in maintaining oxygenation during rapid sequence induction (RSI) for endotracheal intubation in adult patients. Participants will be randomly assigned in a 1:1 ratio to receive either HFNC or TFM for preoxygenation before induction of anesthesia. The primary outcome is the lowest peripheral oxygen saturation (SpO₂) recorded from induction until successful endotracheal intubation. Secondary outcomes include the incidence of oxygen desaturation (\\\u003C90%), duration of apnea, duration of laryngoscopy, intubation time, number of intubation attempts, and peri-intubation complications. The study will determine whether HFNC provides superior oxygenation compared with conventional face mask preoxygenation during RSI and may contribute to improving airway management protocols and patient safety.",[143,24,111,144],"Hypoxemia","Rapid Sequence Induction","2026-07-22",{"date":147,"type":34},"2026-07-23",{"date":149,"type":20},"2026-08-01",{"date":151,"type":20},"2027-02-20",{"name":153,"class":41},"Khyber Teaching Hospital",{"id":155,"slug":156,"hasResults":12,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":160,"eligibilityCriteria":161,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":162,"enrollmentInfo":163,"targetDuration":4,"studyType":106,"phases":165,"briefSummary":166,"conditions":167,"keywords":170,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":178,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":42},"100631498","ventilation-safety-in-beach-chair-shoulder-surgery-safelm-versus-i-gel-100631498","NCT07501468","Ventilation Safety in Beach Chair Shoulder Surgery: SafeLM Versus I-gel","Comparison of SafeLM™ Video Laryngeal Mask and I-gel® for Ventilation Safety After Transition to Beach Chair Position in Patients Undergoing Shoulder Surgery: A Prospective Randomized Controlled Study","SAFE-BCP","Inclusion Criteria:\n\n* Patients aged 18-80 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Scheduled for elective shoulder surgery\n* Body mass index (BMI) between 18-40 kg\u002Fm\\^2\n* Adequate preoperative fasting (approximately 8 hours)\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Age \\\u003C18 or \\>80 years\n* Refusal to participate\n* ASA physical status \\>= IV\n* BMI \\>40 kg\u002Fm\\^2\n* Failure of supraglottic airway device placement after three attempts\n* Revision surgery\n* Multiple trauma\n* Maxillofacial fracture\n* Active malignancy receiving radiotherapy or chemotherapy\n* Active infection or ongoing antibiotic therapy (except prophylaxis)\n* Chronic steroid or immunosuppressive therapy\n* Full stomach\n* Gastroesophageal reflux disease\n* History of gastric surgery\n* Gastroparesis\n* Known egg allergy","80 Years",{"count":164,"type":20},70,[108],"This study aims to compare the performance of SafeLM™ video laryngeal mask airway and i-gel® supraglottic airway device in patients undergoing shoulder surgery in the beach chair position under general anesthesia. The primary objective is to evaluate oropharyngeal leak pressure (OLP) within the first 10 minutes after transition to the beach chair position. Secondary objectives include assessment of ventilation safety, need for airway interventions, and postoperative airway-related complications. This prospective randomized study will provide data on the effectiveness and safety of a video-guided supraglottic airway device compared to a conventional device in a clinically challenging position.",[24,168,169,56],"Shoulder Surgery","General Anesthetic",[171,172,173,174,175,176],"Oropharyngeal Leak Pressure","SafeLM","i-gel","Ventilation Safety","Beach Chair Position","Video Laryngeal Mask Airway","2026-07-11",{"date":179,"type":34},"2026-07-14",{"date":181,"type":34},"2026-04-15",{"date":183,"type":20},"2026-09-15",{"name":185,"class":41},"Ankara City Hospital Bilkent",{"id":187,"slug":188,"hasResults":12,"nctId":189,"briefTitle":190,"officialTitle":191,"acronym":192,"eligibilityCriteria":193,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":194,"targetDuration":4,"studyType":106,"phases":195,"briefSummary":196,"conditions":197,"keywords":200,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":214,"leadSponsor":215,"locationsCount":42},"100647255","bronchoscopic-versus-airway-exchange-catheter-guided-endotracheal-tube-exchange-100647255","NCT07706309","Bronchoscopic Versus Airway Exchange Catheter-Guided Endotracheal Tube Exchange","Bronchoscopic Endotracheal Tube Exchange as an Alternative to Airway Exchange Catheter-Guided Tube Exchange: A Prospective Study","Bronchex","Inclusion Criteria:\n\n* Human body donor preserved using the Thiel embalming method.\n* Intact trachea without relevant postmortem or preparation-related lesions.\n* Documented consent for scientific use of the body and confirmation of anatomical suitability by the Institute of Anatomy.\n* Sufficient mobility of the neck, jaw, and laryngeal region to permit realistic tube-exchange maneuvers.\n\nExclusion Criteria:\n\n* Tumor or stenosis involving the larynx, trachea, or central airways.\n* Previous surgery or radiotherapy involving the larynx or oral cavity.\n* Previous pneumonectomy.\n* Previous tracheotomy or laryngectomy.\n* Inability to achieve safe or standardized positioning of the cadaver.\n* Incomplete consent documentation or unclear provenance.\n* Preservation using a fixation method other than the Thiel method.",{"count":94,"type":20},[108],"This prospective experimental study compares two methods for replacing an endotracheal tube in Thiel-embalmed body donors. The conventional method uses an airway exchange catheter based on the Seldinger technique, whereas the investigational method uses a flexible bronchoscope to provide direct visual guidance throughout the exchange.\n\nThe primary outcome is the duration of interrupted ventilation, measured from cessation of ventilation until ventilation is resumed through a correctly positioned replacement tube. Secondary outcomes include unsuccessful tube exchange requiring complete reintubation, duration of individual procedural steps, procedures lasting more than 60 seconds, use of additional rescue equipment, and unforeseen technical difficulties.\n\nBoth techniques will be performed in two Thiel-embalmed donated human bodies using an alternating sequence. Four experienced physicians will perform 40 tube exchanges per technique, resulting in a total of 80 procedures.",[198,24,111,199],"Endotracheal Tube Exchange","Reintubation",[201,202,203,204,205,206,207,208,209],"Airway exchange catheter","bronchoscopy","interventional pneumology","tube exchange","reintubation","endotracheal tube exchange","apnea time","airway management","critical care","2026-07-10",{"date":212,"type":34},"2026-07-15",{"date":210,"type":34},{"date":210,"type":20},{"name":216,"class":41},"Léo Franchetti",{"id":218,"slug":219,"hasResults":12,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":4,"eligibilityCriteria":223,"healthyVolunteers":12,"sex":16,"minAge":224,"maxAge":4,"enrollmentInfo":225,"targetDuration":4,"studyType":106,"phases":227,"briefSummary":228,"conditions":229,"keywords":4,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":230,"lastUpdatePostDateStruct":231,"startDateStruct":232,"completionDateStruct":233,"leadSponsor":235,"locationsCount":4},"100647068","first-attempt-success-in-tracheal-intubation-through-supraglottic-airway-devices-without-fiberoptic-guidance-100647068","NCT07704723","First Attempt Success in Tracheal Intubation Through Supraglottic Airway Devices Without Fiberoptic Guidance","First Attempt Success in Tracheal Intubation Through Supraglottic Airway Devices Without Fiberoptic Guidance: Conventional vs. Video-assisted Supraglottic Airway Devices, a Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 19 years or older.\n* Scheduled to undergo elective surgery under general anesthesia requiring tracheal intubation.\n\nExclusion Criteria:\n\n* Refusal or inability to provide informed consent.\n* Emergency surgery.\n* History of gastroesophageal reflux disease.\n* Previous surgery or radiotherapy involving the upper airway.\n* Severely loose teeth.\n* Any condition considered by the investigator to make study participation inappropriate.","19 Years",{"count":226,"type":20},204,[108],"This randomized controlled trial aims to compare the first-attempt success rate of tracheal intubation through supraglottic airway devices using a conventional intubating supraglottic airway device versus a video-assisted supraglottic airway device without fiberoptic guidance in adult patients undergoing elective surgery under general anesthesia. A total of 204 participants will be randomly assigned to one of the two groups. The primary outcome is the first-attempt success rate of tracheal intubation through the supraglottic airway device. Secondary outcomes include intubation time, number of intubation attempts, overall intubation success, hemodynamic changes, airway-related complications, postoperative sore throat and hoarseness, and adverse events. The results of this study may help identify a safe and effective airway management strategy when fiberoptic bronchoscopy is unavailable.",[24],"2026-07-09",{"date":212,"type":34},{"date":149,"type":20},{"date":234,"type":20},"2029-08-01",{"name":236,"class":41},"Seoul National University Hospital",{"id":238,"slug":239,"hasResults":12,"nctId":240,"briefTitle":241,"officialTitle":242,"acronym":4,"eligibilityCriteria":243,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":244,"enrollmentInfo":245,"targetDuration":4,"studyType":106,"phases":247,"briefSummary":248,"conditions":249,"keywords":252,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":259,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":42},"100645990","comparison-of-three-airway-intubation-devices-for-first-attempt-success-in-general-anesthesia-patients-100645990","NCT07699653","Comparison of Three Airway Intubation Devices for First-Attempt Success in General Anesthesia Patients","Application of SPHJ-II, Visual Lighted Stylet, and Visual Intubation Fiberscope in Endotracheal Intubation in Patients Under General Anesthesia","Inclusion Criteria:\n\n* Age 18 to 65 years, inclusive. American Society of Anesthesiologists (ASA) physical status I to III. Scheduled for surgery under general anesthesia requiring endotracheal intubation.\n\nThe participant or legally authorized representative is fully informed of the purpose, methods, potential risks, and possible benefits of the study and provides written informed consent.\n\nExclusion Criteria:\n\n* Anticipated severe difficulty with mask ventilation, such as severe obesity (BMI \\> 35 kg\u002Fm²) with obstructive sleep apnea syndrome, history of neck radiotherapy, craniofacial malformation, or other conditions judged by the attending anesthesiologist to confer high risk for mask ventilation, and patients requiring awake tracheal intubation.\n\nCervical spine instability, cervical trauma, rheumatoid arthritis involving the cervical spine, ankylosing spondylitis, or any condition requiring absolute cervical immobilization during the procedure.\n\nSignificant airway involvement identified preoperatively, including imaging evidence of tracheal narrowing with minimal diameter \\\u003C 5 mm, severe tracheal compression, displacement or collapse, stridor at rest or after activity, vocal cord paralysis with dyspnea, giant thyroid mass with orthopnea, or other oral, pharyngeal, or laryngeal tumor, edema, stenosis, abscess, or severe upper airway anatomical abnormality affecting glottic exposure or endotracheal tube passage.\n\nHigh risk of reflux and aspiration. Severe cardiovascular disease, severe respiratory disease, severe hepatic or renal dysfunction, severe coagulation disorder, frailty, pregnancy or breastfeeding, or known allergy.\n\nAny other condition making the patient unsuitable for participation in the study, such as psychiatric illness, communication disorder, or poor compliance.","65 Years",{"count":246,"type":20},549,[108],"The goal of this clinical trial is to compare three airway intubation devices in adult patients undergoing general anesthesia who require tracheal intubation. The main questions it aims to answer are:\n\n* Does the SPHJ-II video-assisted adjustable red-light fluoroscopic tracheal intubation scope improve first-attempt intubation success compared with a visual lighted stylet and a visual intubation fiberscope?\n* How do the three devices compare in intubation efficiency, intubation-related complications, and peri-intubation physiological responses?\n\nResearchers will compare the SPHJ-II, the visual lighted stylet, and the visual intubation fiberscope to evaluate their performance during tracheal intubation.\n\nParticipants will be randomly assigned to one of the three device groups and undergo tracheal intubation during general anesthesia using the assigned device.",[24,250,251],"General Anesthesia","Tracheal Intubation",[253,254,255,256,257],"SPHI-II","Visual lighted stylet","Visual intubation fiberscope","First-attempt intubation success","Randomized controlled trial","2026-07-08",{"date":260,"type":34},"2026-07-13",{"date":262,"type":20},"2026-07",{"date":264,"type":20},"2026-12-31",{"name":266,"class":41},"Guangzhou University of Chinese Medicine",{"id":268,"slug":269,"hasResults":12,"nctId":270,"briefTitle":271,"officialTitle":272,"acronym":273,"eligibilityCriteria":274,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":275,"targetDuration":4,"studyType":106,"phases":276,"briefSummary":277,"conditions":278,"keywords":279,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":289,"lastUpdatePostDateStruct":290,"startDateStruct":292,"completionDateStruct":294,"leadSponsor":296,"locationsCount":42},"100639500","i-scoop-vs-c-mac-d-blade-videolaryngoscope-for-airway-management-under-spontaneous-breathing-and-analgosedation-100639500","NCT07624162","I-scoop vs. C-Mac D-Blade Videolaryngoscope for Airway Management Under Spontaneous Breathing and Analgosedation","Practicability of Airway Management With the Videolaryngoscopes I-scoop and C-Mac D-Blade Under Spontaneous Breathing and Analgosedation - A Prospective, Randomized, Monocentric Trial","OWN BREATH 2","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Scheduled surgical procedure or intervention under general anesthesia\n* Capacity to give informed consent (free and independent decision-making capacity)\n* Willingness to provide written informed consent after comprehensive verbal and written information about study aims, procedures, and risks\n\nExclusion Criteria:\n\n* Lack of, or withdrawal of, written informed consent\n* Lack of capacity to consent or legal guardianship for health-related decisions\n* Insufficient German language skills for qualified verbal and written informed consent (exclusion to protect patients, since legally valid and substantively meaningful consent is not possible without secured language comprehension)\n* Pregnancy or breastfeeding\n* Current opioid therapy or chronic opioid therapy discontinued less than 1 month before the procedure\n* Known drug or alcohol dependence\n* Known hypersensitivity or allergy to lidocaine or its excipients (glycerol, propyl-4-hydroxybenzoate, methyl-4-hydroxybenzoate)\n* Severe psychiatric disorder impairing capacity to consent or to cooperate\n* Indication for nasal intubation\n* Non-pain-related limitation of mouth opening to less than 16 mm\n* Severe comorbidities with particular risk in the context of the study intervention (e.g., unstable cardiac or pulmonary disease, uncontrolled epilepsy)\n* Participation in another clinical study within the previous 30 days that could influence the present study question",{"count":51,"type":20},[108],"The purpose of this clinical trial is to investigate whether the videolaryngoscope i-scoop makes airway management under spontaneous breathing and analgosedation more clinically practicable than the established standard device, the C-Mac D-Blade videolaryngoscope, in adults undergoing surgery under general anesthesia.\n\nThe main questions it aims to answer are:\n\n• Is good clinical practicability - defined as a successful, easy, and complication-free intubation under spontaneous breathing - more frequently achieved with the i-scoop than with the C-Mac D-Blade?\n\nResearchers will compare the standardized airway management procedure under spontaneous breathing using either the i-scoop or the C-Mac D-Blade.\n\nParticipants will:\n\n* continue breathing on their own during the procedure\n* be randomly assigned (1:1) to one of the two videolaryngoscopes\n* receive standardized analgosedation and topical lidocaine anesthesia of the upper airway before the breathing tube is placed\n* be asked about discomfort and recall of the procedure after surgery (in the recovery room, on postoperative day 1, and at 7 days post-intubation) by a blinded interviewer",[24],[83,280,281,282,283,284,285,286,287,288],"i-scoop","C-Mac D-Blade","Spontaneous breathing","Conscious sedation","Analgosedation","Topical airway anesthesia","Bladeless laryngoscope","Anatomy-guided intubation","Clinical practicability","2026-06-20",{"date":291,"type":34},"2026-06-25",{"date":293,"type":34},"2026-06-18",{"date":295,"type":20},"2028-04-30",{"name":297,"class":41},"Hannover Medical School",{"id":299,"slug":300,"hasResults":12,"nctId":301,"briefTitle":302,"officialTitle":303,"acronym":4,"eligibilityCriteria":304,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":305,"enrollmentInfo":306,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":308,"conditions":309,"keywords":313,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":318,"lastUpdatePostDateStruct":319,"startDateStruct":321,"completionDateStruct":322,"leadSponsor":323,"locationsCount":4},"100619603","evaluation-of-anterior-neck-ultrasound-in-predicting-difficult-airway-in-obese-patients-100619603","NCT07346768","Evaluation of Anterior Neck Ultrasound in Predicting Difficult Airway in Obese Patients","Ultrasound Assessment of Anterior Neck Soft Tissue Thickness to Predict Difficult Airway Risk in Obese Patients Undergoing for Surgery Under General Anesthesia: an Observational Study","Inclusion Criteria:\n\n* Age 18-70 years\n* ASA physical status I-III\n\n  \\* BMI \\>25 kg\u002Fm²\n* Scheduled for elective surgery under general anesthesia\n\nExclusion Criteria:\n\n* Emergency surgery\n* Pregnancy\n* Maxillofacial anomalies or neck masses\n* Rapid sequence induction\n* Previous history of difficult intubation\n* BMI \\>60 kg\u002Fm²","70 Years",{"count":307,"type":20},52,"Obese patients are at increased risk of difficult airway management due to anatomical changes in the anterior neck soft tissues. Accurate preoperative prediction of difficult airway remains challenging using conventional clinical airway assessment tests alone.\n\nThis prospective observational study aims to evaluate the role of ultrasound assessment of anterior neck soft tissue thickness in predicting difficult airway risk in overweight and obese adult patients undergoing elective surgery under general anesthesia. Ultrasound-based anterior neck measurements will be compared with standard clinical airway assessment parameters to determine their diagnostic accuracy for difficult laryngoscopy and intubation.\n\nThe results of this study may contribute to improved preoperative airway risk stratification and safer airway management in obese patients.",[310,24,311,312],"Ultrasonography","Intubation, Intratracheal","Obesity and Overweight",[314,315,316,317],"Obesity","difficult airway","anterior neck ultrasound","ultrasonography","2026-06-12",{"date":320,"type":34},"2026-06-16",{"date":289,"type":20},{"date":289,"type":20},{"name":324,"class":41},"Gaziantep City Hospital",{"id":326,"slug":327,"hasResults":12,"nctId":328,"briefTitle":329,"officialTitle":330,"acronym":331,"eligibilityCriteria":332,"healthyVolunteers":103,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":333,"targetDuration":4,"studyType":106,"phases":335,"briefSummary":336,"conditions":337,"keywords":340,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":345,"lastUpdatePostDateStruct":346,"startDateStruct":348,"completionDateStruct":350,"leadSponsor":352,"locationsCount":42},"100639898","mental-rehearsal-in-emergency-cricothyroidotomy-training-100639898","NCT07625072","Mental Rehearsal in Emergency Cricothyroidotomy Training","Effect of Mental Rehearsal Training on the Effectiveness of Emergency Cricothyroidotomy Training Among Medical Personnel.","MERIT","Inclusion Criteria:\n\n* Medical personnel, including anesthesiology and intensive care specialists, residents, and nursing staff employed within Anesthesiology and Intensive Care Departments of the Medical University of Warsaw network.\n* No prior experience with the use of Mental Rehearsal techniques in performing emergency cricothyroidotomy.\n* Informed consent.\n\nExclusion Criteria:\n\n* Medical personnel involved in the training process of study participants in emergency cricothyroidotomy, including instructors, assisting staff, and examiners.\n* Previous experience with the use of Mental Rehearsal techniques for acquiring competencies in performing emergency cricothyroidotomy.\n* Lack of informed consent.",{"count":334,"type":20},60,[108],"Medical staff at the clinic will participate in standard cricothyroidotomy training supplemented with structured mental rehearsal exercises in order to evaluate the usefulness and effectiveness of this approach as a training tool.",[112,338,24,339],"Medical Training","Cricothyroidotomy",[341,342,343,339,24,344],"Mental Rehearsal","Mental Training","eFONA (Emergency Front of Neck Airway)","Critical care","2026-06-01",{"date":347,"type":34},"2026-06-04",{"date":349,"type":20},"2026-06-08",{"date":351,"type":20},"2028-05-01",{"name":353,"class":41},"Medical University of Warsaw",{"id":355,"slug":356,"hasResults":12,"nctId":357,"briefTitle":358,"officialTitle":359,"acronym":4,"eligibilityCriteria":360,"healthyVolunteers":103,"sex":16,"minAge":17,"maxAge":162,"enrollmentInfo":361,"targetDuration":4,"studyType":106,"phases":363,"briefSummary":364,"conditions":365,"keywords":366,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":369,"lastUpdatePostDateStruct":370,"startDateStruct":372,"completionDateStruct":373,"leadSponsor":375,"locationsCount":4},"100639566","multifunctional-oropharyngeal-airway-and-hypoxemia-in-sedated-gi-endoscopy-a-multicenter-rct-100639566","NCT07623863","Multifunctional Oropharyngeal Airway and Hypoxemia in Sedated GI Endoscopy: A Multicenter RCT","Effect of a Novel Multifunctional Oropharyngeal Airway on Hypoxemia in Patients Undergoing Sedated Gastrointestinal Endoscopy: A Multicenter, Prospective, Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 18-80 years;\n* BMI: 18-30 kg\u002Fm²;\n* ASA class I-II;\n* Scheduled to undergo elective sedated gastrointestinal endoscopy;\n* Willing to participate in this study and able to provide written informed consent.\n\nExclusion Criteria:\n\n* Diagnosed respiratory diseases, including asthma, bronchitis, chronic obstructive pulmonary disease (COPD), emphysema, moderate or severe obstructive sleep apnea (OSA), pulmonary embolism, pulmonary edema, lung cancer, or upper respiratory tract infection, etc.;\n* Coagulation disorders, tendency for oral\u002Fnasal bleeding, mucosal injury, or space-occupying lesions;\n* Severe cardiac insufficiency (≤4 MetS);\n* Severe renal insufficiency (acute kidney injury \\[AKI\\] or chronic kidney disease \\[CKD\\] stage 4 or higher);\n* Severe hepatic insufficiency (Child-Pugh class C or worse);\n* Planned therapeutic endoscopy (e.g., polypectomy, endoscopic mucosal resection \\[EMR\\], or other therapeutic procedures);\n* Pregnancy or breastfeeding;\n* Allergy to the study drugs;\n* Emergency surgery;\n* Daily alcohol intake ≥60 grams;\n* History of psychiatric disorders: e.g., depression, severe central nervous system depression, Parkinson's disease, basal ganglia lesions, schizophrenia, epilepsy, Alzheimer's disease;\n* Myasthenia gravis;\n* Participation in other related clinical trials within the past 3 months;\n* Refusal to participate.",{"count":362,"type":20},1518,[108],"This multicenter, prospective, randomized controlled trial aims to evaluate whether a novel multifunctional oropharyngeal airway (MOPA) reduces the incidence of hypoxemia in 1,518 adult patients (ASA I-II, aged 18-80 years) undergoing elective sedated gastrointestinal endoscopy. Patients are randomized 1:1 to receive either the MOPA (which integrates oxygen delivery, PETCO₂ monitoring, and airway support) or conventional nasal cannula with standard mouthpiece. The primary endpoint is the incidence of hypoxemia (75% ≤ SpO₂ \\\u003C 90% for \\\u003C60 seconds) during the procedure. Secondary outcomes include severe hypoxemia, hypercapnia, PETCO₂ monitoring success, airway interventions, adverse events, and satisfaction scores. The study is conducted across 29 centers in China, with centralized randomization via an EDC system, blinded outcome assessment, and statistical analysis using a two-sided alpha of 0.05 (power 90%). Results are expected to provide high-level evidence for optimizing airway management during sedated endoscopy.",[143,24],[367,368,82,257],"Novel multifunctional oropharyngeal airway","Capnography \u002F PETCO₂ monitoring","2026-05-28",{"date":371,"type":34},"2026-06-03",{"date":345,"type":20},{"date":374,"type":20},"2028-06-01",{"name":376,"class":41},"Qianfoshan Hospital",{"id":378,"slug":379,"hasResults":12,"nctId":380,"briefTitle":381,"officialTitle":382,"acronym":383,"eligibilityCriteria":384,"healthyVolunteers":12,"sex":16,"minAge":4,"maxAge":385,"enrollmentInfo":386,"targetDuration":4,"studyType":106,"phases":388,"briefSummary":389,"conditions":390,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":391,"lastUpdatePostDateStruct":392,"startDateStruct":394,"completionDateStruct":396,"leadSponsor":398,"locationsCount":400},"100513594","laryngoscopy-for-neonatal-and-infant-airway-management-with-supplemental-oxygen-at-different-flow-rates-optimise-2-100513594","NCT05967507","Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)","Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2): a Multi-center, Non-inferiority, Prospective Randomized Controlled Trial","OPTIMISE-2","Inclusion Criteria:\n\n* Pediatric patients requiring oral or nasal tracheal intubation for elective, semi-elective, or urgent surgical and non-surgical indications.\n* Neonates and infants up to 52 weeks postconceptual age, with legal guardians providing written informed consent before the intervention\n\nExclusion Criteria:\n\n* Prediction of difficult intubation upon physical examination or previous history of difficult intubation, mandating a technique different than direct laryngoscopy to secure the airway;\n* Congenital heart disease demanding FiO2 \\\u003C 1.0\n* Cardiopulmonary collapse requiring advanced life support\n* Intubation for emergency surgical and non-surgical indications.","52 Weeks",{"count":387,"type":20},1192,[108],"This study aims to investigate the optimal oxygen flow rate needed during tracheal intubation with the C-MAC video laryngoscope (Karl Storz, Tuttlingen, Germany) using Miller-blade or Macintosh-blade size No. 0 or No. 1 in the operating room or intensive care unit. The investigators hypothesize that the difference between low-flow and high-flow supplemental oxygen is negligible.",[24],"2026-05-09",{"date":393,"type":34},"2026-05-12",{"date":395,"type":34},"2023-12-01",{"date":397,"type":20},"2027-09",{"name":399,"class":41},"Thomas Riva",11,{"id":402,"slug":403,"hasResults":12,"nctId":404,"briefTitle":405,"officialTitle":406,"acronym":4,"eligibilityCriteria":407,"healthyVolunteers":12,"sex":16,"minAge":408,"maxAge":409,"enrollmentInfo":410,"targetDuration":4,"studyType":106,"phases":411,"briefSummary":413,"conditions":414,"keywords":417,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":422,"lastUpdatePostDateStruct":423,"startDateStruct":424,"completionDateStruct":426,"leadSponsor":428,"locationsCount":42},"100639649","phase-4-effective-dose-of-alfentanil-combined-with-propofol-for-laryngeal-mask-airway-insertion-in-children-100639649","NCT07581665","Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children","Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children: A Prospective, Up-and-Down Sequential Allocation Study","Inclusion Criteria:\n\n* Aged 7 to 12 years\n* Undergoing elective day surgery\n* ASA physical status I-II\n* Body Mass Index (BMI) between 14 and 24 kg\u002Fm²\n* Accompanied by a fully capable guardian within 24 hours after discharge\n\nExclusion Criteria:\n\n* Allergy to opioids\n* Unresolved upper respiratory tract infection within the past 1 week\n* Abnormal heart, lung, liver, or kidney function, or metabolic diseases\n* Airway anatomical abnormalities (e.g., micrognathia, laryngomalacia, macroglossia) or OSAHS (Obstructive Sleep Apnea-Hypopnea Syndrome)\n* Use of analgesics, sedatives, or other psychotropic drugs within the past 2 weeks\n* Refusal to sign the informed consent form","7 Years","12 Years",{"count":105,"type":20},[412],"PHASE4","This study uses a prospective, up-and-down sequential allocation method to determine the median effective dose (ED50) and 95% effective dose (ED95) of alfentanil combined with propofol for successful laryngeal mask airway (LMA) insertion in children aged 7-12 undergoing elective day surgery.",[415,24,250,416],"Pediatric Anesthesia","LMA",[418,419,415,416,420,421],"Alfentanil","Propofol","Dixon Method","Effective dose","2026-05-05",{"date":393,"type":34},{"date":425,"type":20},"2026-05-01",{"date":427,"type":20},"2027-03-30",{"name":429,"class":41},"Zhongshan Ophthalmic Center, Sun Yat-sen University",{"id":431,"slug":432,"hasResults":12,"nctId":433,"briefTitle":434,"officialTitle":435,"acronym":4,"eligibilityCriteria":436,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":437,"targetDuration":439,"studyType":21,"phases":4,"briefSummary":440,"conditions":441,"keywords":444,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":422,"lastUpdatePostDateStruct":450,"startDateStruct":452,"completionDateStruct":454,"leadSponsor":456,"locationsCount":42},"100639089","taiwan-ed-airway-quality-surveillance-registry-tear-100639089","NCT07574450","Taiwan ED Airway Quality Surveillance Registry (TEAR)","The Taiwan ED Airway Quality Surveillance Registry (TEAR): A Prospective Multicenter Observational Study","Inclusion Criteria:\n\n* Undergoing tracheal intubation in the emergency department during the study period\n\nExclusion Criteria:\n\n* Prehospital intubation; intubation performed solely for elective anesthesia\u002Fprocedural sedation outside emergency indications",{"count":438,"type":20},1200,"1 Month","This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan. The registry focuses on process quality indicators, including first-pass success, and patient-safety outcomes, including hypoxemia, hypotension, and peri-intubation cardiac arrest within 30 minutes of intubation. Routinely generated laboratory and physiologic variables are also collected to improve risk stratification and identify predictors of major adverse events. The study is non-interventional and does not alter clinical care.",[24,251,442,443],"Emergency Department","Peri-intubation Adverse Events",[445,446,447,448,449],"first-pass success","hypoxemia","hypotension","cardiac arrest","registry",{"date":451,"type":34},"2026-05-08",{"date":453,"type":20},"2026-08",{"date":455,"type":20},"2029-12",{"name":457,"class":41},"Chang Gung Memorial Hospital",{"id":459,"slug":460,"hasResults":12,"nctId":461,"briefTitle":462,"officialTitle":463,"acronym":4,"eligibilityCriteria":464,"healthyVolunteers":103,"sex":16,"minAge":17,"maxAge":465,"enrollmentInfo":466,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":468,"conditions":469,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":425,"lastUpdatePostDateStruct":472,"startDateStruct":474,"completionDateStruct":476,"leadSponsor":478,"locationsCount":42},"100569977","upper-airway-ultrasound-evaluation-100569977","NCT06701253","Upper Airway Ultrasound Evaluation","Ultrasound of the Anterior Neck Tissues, as a New Tool in the Evaluation of Difficult Airway.","Inclusion Criteria: age\\>18, elective surgery under general anesthesia with endotracheal intubation\n\nExclusion Criteria:\n\n* obstetric surgeries,\n* pregnancy,\n* non elective surgeries,\n* patients with previous surgeries involving the anterior surface of the neck (i.e., thyroid surgery),\n* patients with history of cervical radiation.","99 Years",{"count":467,"type":20},500,"Current guidelines support the use of predictive clinical tests in the evaluation of difficult airway, meaning either difficult bag and mask ventilation, conventional laryngoscopy and\u002For endotracheal intubation. However, despite the clinical use of these predictive tests, unpredictive difficult laryngoscopy complicates 1.5-13% of cases. Life threatening scenarios may be encountered in patients with difficult or impossible bag and mask ventilation.\n\nAnaesthesiologists are familiar with the use of ultrasound, with peripheral nerve blockade and central vascular access representing the most popular applications during the last decades. The ultrasound provides real time and accurate images. According to the current literature, there are only a handful of studies relevant to the application of point of care ultrasound (POCUS), as a new tool in the upper airway evaluation. It is a new field of research with high interest.\n\nThis is a prospective observational study to investigate if specific ultrasound measurements of the anterior neck can serve as predictors of difficult airway. The ultrasound parameters will be measured preoperatively, during the preanaesthetic evaluation, along with standard clinical prognostic tools, like the mallampati score. The ultrasound parameters to be investigated are:\n\n1. the distance from thyroid isthmus to skin surface,\n2. the distance from the hyoid bone to the skin surface,\n3. the distance from the anterior commissure of vocal cords to the skin surface,\n4. the distance from skin to the trachea at the level of jugular notch,\n5. the distance from skin to epiglottis corresponding to half of the distance between thyroid cartilage and hyoid bone,\n6. and the angle between glottis and epiglottis. After the induction in anaesthesia, the Cormack Lehane score (grading of the laryngoscopy view) and the Han scale (grading of the degree of difficulty of bag and mask ventilation) will also be recorded.\n\nThe goal of this study is the investigation of the role of POCUS in the evaluation of difficult bag and mask ventilation and difficult intubation. The primary endpoint is the incidence of difficult bag and mask ventilation and the incidence of difficult laryngoscopy and intubation. Secondary endpoints are the correlations between clinical prognostic tools of difficult airway and the POCUS parameters under investigation.",[24,470,471],"Point of Care","Ultrasound",{"date":473,"type":34},"2026-05-04",{"date":475,"type":34},"2021-11-08",{"date":477,"type":20},"2028-06-09",{"name":479,"class":41},"University of Ioannina",{"id":481,"slug":482,"hasResults":12,"nctId":483,"briefTitle":484,"officialTitle":485,"acronym":4,"eligibilityCriteria":486,"healthyVolunteers":103,"sex":16,"minAge":17,"maxAge":487,"enrollmentInfo":488,"targetDuration":4,"studyType":106,"phases":490,"briefSummary":491,"conditions":492,"keywords":493,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":498,"lastUpdatePostDateStruct":499,"startDateStruct":501,"completionDateStruct":503,"leadSponsor":505,"locationsCount":94},"100579562","lma-i-gel-versus-lma-protector-during-minor-urological-procedures-under-general-anesthesia-in-adult-patients-100579562","NCT06825910","LMA I-Gel Versus LMA Protector During Minor Urological Procedures Under General Anesthesia in Adult Patients","Laryngeal Mask Airway I-Gel and Laryngeal Mask Airway Protector for Minor Urological Procedures Under General Anesthesia in Adult Patients: A Randomized Comparative Study","Inclusion Criteria:\n\n* ASA I-II\n* Patients older than 18 years\n* Procedures in supine and lithotomy position\n\nExclusion Criteria:\n\n* Tumors or anatomical anomalies of the upper airway\n* Known history of difficult intubation\n* Limited mouth opening less than 2cm\n* Decreased compliance of the lungs or the thoracic cage\n* Need of mechanical ventilation after the surgery","90 Years",{"count":489,"type":20},100,[108],"This will be a randomized comparative study comparing the two supraglottic devices i-gel and Protector, intraoperatively, during minor urological procedures under general anesthesia in adult patient.",[24,250],[416,494,495,496,497],"Protector","Airway Device Evaluation","iGel","Airway Device Comparison","2026-04-24",{"date":500,"type":34},"2026-04-27",{"date":502,"type":34},"2025-02-01",{"date":504,"type":20},"2026-12-30",{"name":506,"class":41},"Nikolopoulou Maria Zozefin",{"id":508,"slug":509,"hasResults":12,"nctId":510,"briefTitle":511,"officialTitle":512,"acronym":4,"eligibilityCriteria":513,"healthyVolunteers":103,"sex":16,"minAge":514,"maxAge":515,"enrollmentInfo":516,"targetDuration":517,"studyType":21,"phases":4,"briefSummary":518,"conditions":519,"keywords":523,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":527,"lastUpdatePostDateStruct":528,"startDateStruct":530,"completionDateStruct":532,"leadSponsor":534,"locationsCount":42},"100633151","comparison-of-two-airway-devices-i-gel-and-air-q-in-children-aged-1-10-years-during-general-anesthesia-100633151","NCT07522957","Comparison of Two Airway Devices (I-Gel and Air-Q) in Children Aged 1-10 Years During General Anesthesia","Effect of I-gel and Air-Q SP LMAs on Oropharyngeal Leak Pressure and Gastric Insufflation in Children: An Ultrasonography-Guided Randomized Study","Inclusion Criteria:\n\n* Children aged 1-10 years\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Scheduled for elective (non-emergency) surgery under general anesthesia\n* Planned use of a supraglottic airway device for airway management\n* Written informed consent obtained from a parent or legal guardian\n\nExclusion Criteria:\n\n* History of conditions associated with increased risk of aspiration (e.g., gastroesophageal reflux)\n* Known or predicted difficult airway (e.g., Mallampati score ≥ 3)\n* Congenital or acquired abnormalities of the face, neck, or upper airway\n* Active upper respiratory tract infection\n* Presence of significant pulmonary disease (e.g., asthma, bronchopulmonary dysplasia, cystic fibrosis)\n* Body mass index above the 95th percentile for age (morbid obesity)\n* Emergency surgery\n* Previous complications related to supraglottic airway device use\n* Failure of device placement or need to switch to an alternative airway management technique\n* Refusal of participation by parent or legal guardian","1 Year","10 Years",{"count":334,"type":20},"1 Day","This study aims to compare two commonly used airway devices (I-gel and Air-Q) in children aged 1-10 years undergoing general anesthesia for surgery. These devices help doctors keep the airway open and support breathing during the operation. The study will evaluate how well each device works, how easy they are to place, and whether they cause air to enter the stomach. Ultrasound will be used to safely check the position of the device and detect any air in the stomach. The results of this study may help improve the safety and effectiveness of airway management in children during anesthesia.",[520,310,521,24,522],"Anesthesia General","Laryngeal Mask Airways","Child",[82,27,524,310,525,526],"Pediatric patients","Gastric insufflation","Supraglottic airway devices","2026-04-21",{"date":529,"type":34},"2026-04-23",{"date":531,"type":20},"2026-04",{"date":533,"type":20},"2026-05",{"name":535,"class":130},"Ankara Etlik City Hospital",{"id":537,"slug":538,"hasResults":12,"nctId":539,"briefTitle":540,"officialTitle":541,"acronym":542,"eligibilityCriteria":543,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":544,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":546,"conditions":547,"keywords":548,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":553,"lastUpdatePostDateStruct":554,"startDateStruct":555,"completionDateStruct":557,"leadSponsor":558,"locationsCount":42},"100635073","tmh-and-ultrasound-for-difficult-airway-prediction-100635073","NCT07547943","TMH And Ultrasound For Difficult Airway Prediction","Comparative Evaluation Of Thyromental Height And Ultrasonographic Airway Measurements In Predicting Difficult Airway: A Prospective Observational Study","TMH-USG","Inclusion Criteria:\n\nAdult patients aged 18 years and older Patients scheduled for elective surgery under general anesthesia Patients requiring endotracheal intubation Patients who provide written informed consent\n\nExclusion Criteria:\n\n* Patients with known upper airway pathology (e.g., tumor, trauma, infection) Patients with previous head and neck surgery or anatomical deformity affecting airway evaluation Patients with limited mouth opening (\\\u003C3 cm) or severe cervical spine restriction Patients with contraindications to ultrasonographic examination Patients requiring rapid sequence induction or emergency surgery Patients who refuse to participate",{"count":545,"type":20},240,"This prospective observational study aims to evaluate the predictive value of thyromental height (TMH) and ultrasonographic airway measurements in predicting difficult airway in adult patients undergoing elective surgery under general anesthesia.\n\nPreoperative airway assessment will include standard clinical evaluation, TMH measurement, and ultrasonographic measurements of anterior neck soft tissue. Perioperative airway management data, including intubation difficulty, number of attempts, and Cormack-Lehane classification, will be recorded.\n\nThe relationship between preoperative measurements and difficult airway will be analyzed to determine their predictive accuracy and clinical usefulness.",[112,24],[549,550,551,552],"Thyromental Height","Airway Ultrasound","Difficult Intubation","Cormack-Lehane","2026-04-17",{"date":529,"type":34},{"date":556,"type":20},"2026-05-15",{"date":66,"type":20},{"name":559,"class":130},"Bursa City Hospital",{"id":561,"slug":562,"hasResults":12,"nctId":563,"briefTitle":564,"officialTitle":565,"acronym":566,"eligibilityCriteria":567,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":244,"enrollmentInfo":568,"targetDuration":4,"studyType":106,"phases":570,"briefSummary":571,"conditions":572,"keywords":574,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":553,"lastUpdatePostDateStruct":579,"startDateStruct":580,"completionDateStruct":582,"leadSponsor":584,"locationsCount":42},"100612161","evaluation-of-sacovlm-video-laryngeal-mask-for-airway-management-in-military-medics-100612161","NCT07249983","Evaluation of SaCoVLM™ Video Laryngeal Mask for Airway Management in Military Medics","Evaluation of SaCoVLM™ Video Laryngeal Mask Airway for Airway Management by Inexperienced Military Medics: A Two-Phase Feasibility Study","SAVER","Inclusion Criteria:\n\n* Elective surgery\n* ASA I-II\n* need for airway management\n\nExclusion Criteria:\n\n* Pregnancy\n* known airway abnormalities\n* allergy to anesthetics",{"count":569,"type":20},50,[108],"A prospective, two-phase interventional study evaluating the performance, safety, and usability of the SaCoVLM™ video laryngeal mask airway for airway management by military medics with limited intubation experience. The study includes simulation-based training and clinical application in sedated patients undergoing elective surgery.",[24,251,573],"Anesthesia",[575,576,577,578],"SaCoVLM™","Video Laryngeal Mask","Military Medic Training","Emergency Airway",{"date":527,"type":34},{"date":581,"type":34},"2026-03-01",{"date":583,"type":20},"2027-01",{"name":585,"class":41},"Charles University, Czech Republic",{"id":587,"slug":588,"hasResults":12,"nctId":589,"briefTitle":590,"officialTitle":591,"acronym":4,"eligibilityCriteria":592,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":593,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":595,"conditions":596,"keywords":601,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":603,"lastUpdatePostDateStruct":604,"startDateStruct":606,"completionDateStruct":608,"leadSponsor":610,"locationsCount":42},"100610009","induction-agent-choice-with-early-mortality-and-prognostic-outcomes-in-critically-ill-patients-100610009","NCT07222007","Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients","Association of Induction Agent Choice With Early Mortality and Prognostic Outcomes in Critically Ill Patients: A Large-Scale Retrospective Cohort Analysis","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Admission to the surgical ICU for critical care\n* Administration of one of the studied induction agents\n* Availability of complete clinical data\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Absence of documented induction agent administration\n* Incomplete or missing medical records",{"count":594,"type":20},4,"The aim of this retrospective cohort study is to compare the safety and efficacy of induction agents for tracheal intubation in critically ill adult patients.",[597,598,599,24,419,600],"Critically Ill","Intubation Complication","Oxygenation","Ketamine",[602],"intubation, critically ill patients, airway management","2026-04-11",{"date":605,"type":34},"2026-04-14",{"date":607,"type":20},"2026-04-18",{"date":609,"type":20},"2026-07-01",{"name":611,"class":130},"Zeliha Alicikus",{"id":613,"slug":614,"hasResults":12,"nctId":615,"briefTitle":616,"officialTitle":616,"acronym":4,"eligibilityCriteria":617,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":618,"targetDuration":4,"studyType":106,"phases":620,"briefSummary":621,"conditions":622,"keywords":4,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":625,"lastUpdatePostDateStruct":626,"startDateStruct":628,"completionDateStruct":630,"leadSponsor":632,"locationsCount":4},"100631108","clinical-study-on-the-efficacy-of-subglottic-suction-in-mechanically-ventilated-patients-guided-by-bedside-ultrasound-100631108","NCT07496385","Clinical Study on the Efficacy of Subglottic Suction in Mechanically Ventilated Patients Guided by Bedside Ultrasound","Inclusion Criteria:\n\n* 1\\. Patients admitted to the ICU with the patient or their legal representative having signed an informed consent form; 2. Patients expected to have an oral artificial airway in place for ≥72 hours; 3. Patients using tracheostomy tubes with subglottic suctioning\n\nExclusion Criteria:\n\n* 1\\) Severe cervical deformity, extensive subcutaneous emphysema, thick dressing coverage, or severe obesity that prevents clear visualization of the subglottic region by ultrasound.\n\n  2\\) Coagulopathy (platelets \\\u003C50×10⁹\u002FL) or active bleeding tendency, which may induce airway bleeding due to suctioning procedures.\n\n  3\\) Presence of organic airway disease or previous cervical surgery history, affecting assessment of the subglottic region.\n\n  4\\) Tracheostomy patients. 5) Patients allergic to ultrasound coupling agents, or those unable to cooperate with cervical ultrasound examination due to severe agitation.\n\n  6\\) Patients with existing pulmonary infection upon admission. 7) Patients intubated for treatment of known aspiration. 8) History of lung cancer or head and neck cancer that may produce alpha-amylase in the lungs.\n\n  9\\) History of conditions affecting salivary secretion (e.g., Sjögren's syndrome).",{"count":619,"type":20},321,[108],"Subglottic suctioning, as an important airway management technique, has its operational accuracy and safety directly impacting patient prognosis. Therefore, improving the effectiveness and safety of subglottic suctioning has become a focus of clinical attention. Point-of-care ultrasound, which can provide imaging, can be used to guide subglottic suctioning, enhancing the intuitiveness of the procedure. This study aims to evaluate the safety and effectiveness of subglottic suctioning guided by point-of-care ultrasound in mechanically ventilated patients, in order to help standardize clinical practice and improve medical quality.",[623,624,24],"Ultrasound Guidance","Subglottic Airway Injury","2026-03-22",{"date":627,"type":34},"2026-03-27",{"date":629,"type":20},"2026-04-01",{"date":631,"type":20},"2027-08-01",{"name":633,"class":41},"Ruijin Hospital",{"id":635,"slug":636,"hasResults":12,"nctId":637,"briefTitle":638,"officialTitle":639,"acronym":640,"eligibilityCriteria":641,"healthyVolunteers":103,"sex":16,"minAge":642,"maxAge":643,"enrollmentInfo":644,"targetDuration":4,"studyType":106,"phases":646,"briefSummary":647,"conditions":648,"keywords":651,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":656,"lastUpdatePostDateStruct":657,"startDateStruct":659,"completionDateStruct":660,"leadSponsor":662,"locationsCount":42},"100619946","pediatric-airway-noninferiority-trial-of-devices-for-intubation-assessment-100619946","NCT07351227","Pediatric Airway: Noninferiority Trial of Devices for Intubation Assessment","Comparison of the Effectiveness and Cost-Effectiveness of McGRATH™ MAC and Besdata Videolaryngoscopes in the Orotracheal Intubation of Children: A Non-Inferiority Randomized Clinical Trial","PANDA","Inclusion Criteria:\n\n* The study will include children aged between 6 months and 3 years who are scheduled for elective surgery under general anesthesia at the Children's Institute (Instituto da Criança - ICr) of the Hospital das Clínicas Complex, University of São Paulo Medical School (HC-FMUSP), provided that informed consent is obtained from their parents or legal guardians.\n\nExclusion Criteria:\n\n* Patients under one year of age will be excluded if informed consent is not obtained from their legal guardians, if they are classified as ASA physical status IV or higher, present with hemodynamic instability, or have craniofacial abnormalities or oral deformities suggestive of a potentially difficult airway.","6 Months","3 Years",{"count":645,"type":20},226,[108],"The goal of this clinical trial is to find out whether the BESDATA BD-DF videolaryngoscope works as well as the McGRATH™ MAC videolaryngoscope for placing a breathing tube in infants during surgery. The study will also compare the costs associated with using each device.\n\nThe main questions this study aims to answer are:\n\nIs the BESDATA BD-DF videolaryngoscope as effective as the McGRATH™ MAC videolaryngoscope for successful placement of a breathing tube on the first attempt in infants?\n\nAre there differences between the two devices in terms of procedure time, number of attempts, airway-related complications, and overall costs?\n\nResearchers will compare infants who are intubated using the BESDATA BD-DF videolaryngoscope with infants who are intubated using the McGRATH™ MAC videolaryngoscope to see whether the two devices perform similarly and whether one is more cost-effective than the other.\n\nParticipants will:\n\nBe randomly assigned to have a breathing tube placed using one of the two videolaryngoscopes;\n\nReceive standard general anesthesia for an elective surgical procedure;\n\nHave information collected during and after the procedure to assess safety, effectiveness, and costs.",[311,24,649,650],"Video Laryngoscope","Cost Effectiveness",[83,652,653,654,655],"Pediatric orotracheal intubation","Cost effectiveness","McGrath MAC","BESDATA","2026-03-18",{"date":658,"type":34},"2026-03-20",{"date":581,"type":34},{"date":661,"type":20},"2027-12-31",{"name":663,"class":41},"University of Sao Paulo General Hospital",{"id":665,"slug":666,"hasResults":12,"nctId":667,"briefTitle":668,"officialTitle":669,"acronym":4,"eligibilityCriteria":670,"healthyVolunteers":12,"sex":16,"minAge":17,"maxAge":244,"enrollmentInfo":671,"targetDuration":4,"studyType":106,"phases":672,"briefSummary":673,"conditions":674,"keywords":676,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":680,"lastUpdatePostDateStruct":681,"startDateStruct":683,"completionDateStruct":685,"leadSponsor":687,"locationsCount":42},"100619102","the-90-effective-ventilation-pressure-ep90-for-esophageal-insufflation-avoidance-during-anesthesia-induction-100619102","NCT07340255","The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction","The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: A Bias-Coin Design With Up-and-Down Sequential Allocation Trial","Inclusion Criteria:\n\n1. Age: 18-65 years, regardless of gender;\n2. ASA classification: I-III;\n3. Scheduled for elective general anesthesia surgery;\n4. BMI: 18.0-28.0 kg\u002Fm²;\n5. Preoperative fasting: Solid food \\>6 hours, liquid \\>2 hours;\n6. Less than two from five criteria predicting difficult mask ventilation as described by Langeron et al.(Prediction of difficult mask ventilation. Anesthesiology 2000; 92:1229-36);\n7. No severe underlying conditions such as heart, lung, liver, or kidney disease;\n8. Signed informed consent and ability to cooperate with the study protocol.\n\nExclusion Criteria:\n\n1. Pregnant or breastfeeding women;\n2. History of upper gastrointestinal diseases such as gastroesophageal reflux disease, peptic ulcers, or hiatal hernia;\n3. Recent (within 2 weeks) respiratory infections, chronic cough, similar symptoms, and other known or predictable respiratory system diseases;\n4. Need for emergency surgery or airway obstruction after anesthesia induction requiring urgent intubation;\n5. Inability to achieve adequate oxygenation during mask ventilation (e.g., SpO₂ \\\u003C 92% for 30 seconds, unresponsive to treatment);\n6. History of contraindications or allergies to study medications;\n7. Inability to understand the study content or refusal to cooperate;\n8. Oropharyngeal or facial pathology;\n9. with an indwelling gastric tube, and who had previously undergone gastric surgery.",{"count":334,"type":20},[108],"Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during anesthesia induction and to explore its guiding significance for anesthesia management. The goal is to provide a more precise and personalized ventilation pressure setting standard for clinical anesthesia, thereby enhancing the safety of the anesthesia induction phase.",[24,675],"Induction of Anesthesia",[677,24,678,679],"Esophageal Insufflation","Ventilation","Bias-coin Design","2026-01-13",{"date":682,"type":34},"2026-01-14",{"date":684,"type":34},"2025-09-29",{"date":686,"type":20},"2026-02",{"name":688,"class":41},"Affiliated Hospital of Jiaxing University"]