[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"countryName\":\"Afghanistan\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":196},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,44,75,104,139,169],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100626750","icu-related-out-of-pocket-expenses-icope-100626750",false,"NCT07439692","ICU-related Out of Pocket Expenses (ICOPE)","ICU-related Out of Pocket Expenses (ICOPE) - A Multinational Prospective Study In African And Asian Countries.","ICOPE","Inclusion Criteria:\n\nAll patients admitted to the participating ICUs during a predefined window of 14 days and expected to have a duration of stay \\>24 hours will be eligible for the study.\n\nExclusion Criteria:\n\nlack informed consent.","ALL",{"count":19,"type":20},354,"ESTIMATED","OBSERVATIONAL","The ICU-related Out-of-Pocket Expenses (ICOPE) study is a multinational, prospective observational study conducted in African and Asian countries to quantify ICU-related out-of-pocket expenditures and catastrophic health expenditure among patients and families. The study will include all patients admitted to participating ICUs during a predefined 14-day recruitment window, provided they have an ICU stay longer than 24 hours and informed consent is obtained. A minimum sample size of 354 patients is planned, including both ventilated and non-ventilated patients. Participants will be followed until ICU discharge, with additional follow-up at 30 days and 6 months after admission, resulting in a total study duration of 18 months. The primary objective is to quantify ICU-related out-of-pocket costs and assess the proportion of patients experiencing catastrophic health expenditure, comparing ventilated and non-ventilated groups, while secondary objectives include identifying risk factors for catastrophic expenditure and documenting coping strategies used by families to manage ICU costs.",[24,25],"Cost of ICU","Out of Pocket Expenses",[27,28,29,30],"OOPE","ICU-cost","LMIC","Critical Care","RECRUITING","2026-02-23",{"date":34,"type":35},"2026-02-27","ACTUAL",{"date":37,"type":35},"2024-12-01",{"date":39,"type":20},"2026-07-31",{"name":41,"class":42},"Nat Intensive Care Surveillance - MORU","OTHER",44,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":5},"100451881","phase-4-real-world-safety--efficacy-experience-of-empagliflozin-with-or-without-metformin-in-t2dm-patients---ease-study-100451881","NCT05164263","Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study","Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in Patients With Type II Diabetes Mellitus","EASE","Inclusion Criteria:\n\nPatient with T2DM between 18 to 65 years with HbA1C 7% - 10%, who can give informed consent. Patient uncontrolled on oral antidiabetics and lifestyle modification for at least 3 months. Patient who are empagliflozin naive. eGFR ˃60 mL\u002Fmin\u002F1.73m2.\n\nExclusion Criteria:\n\nType 1 diabetes, History of recurrent urinary tract infection (UTI), fungal infection, renal and\u002For hepatic dysfunctions, where RFT and Urine R\u002FE is abnormal, Diabetic Ketoacidosis and\u002For hyperosmolar hyperglycemic state, severe hypoglycemia, Pregnant or lactating women, Pancreatitis, any serious complications or hypersensitivity.",true,"18 Years","65 Years",{"count":56,"type":20},2000,"INTERVENTIONAL",[59],"PHASE4","Study Objective To evaluate the safety and tolerability of Empagliflozin with or without metformin in patients with Type II Diabetes Mellitus in the Pakistani population.\n\nStudy design Open-label, prospective, observational, single arm, multi-center, post-marketing surveillance study.\n\nSample size The estimated sample size will be n=156. Duration of study 12 months (data lock point will be completion of 6 months' follow-up from the time of last patient's enrollment date) Safety Assessment: Patient will be monitored for Hypoglycemia, Dehydration, Hypotension, Urinary Tract Infections, Fungal Infections, Nausea, Vomiting, Diarrhea, Abdominal Discomfort, Flatulence, Asthenia, Indigestion and Other side effects (if any).\n\nFollow up visits: After recruitment, patient is supposed to have three visits for follow-ups.\n\nVisit 1: 4 to 6 weeks of initiation of therapy. Visit 02: At 12 weeks of initiation of therapy. Visit 03: At 24 weeks of initiation of therapy.\n\nLABORATORY TESTING:\n\nReputable Lab is considered for laboratory testing of diabetes patients i.e. HbA1C%, FBG, RFT and urine R\u002FE. The certified clinical lab will be responsible for receiving and analyzing clinical sample. Patients will have special discount of upto 50% for study related laboratory investigations.\n\nWhere in Urine Routine Examination (Urine R\u002FE), we consider as follows:\n\n* Visual Examination:\n\n  * Urine color: Normal (Yellow), Pale Yellow, Dark Yellow, Brown, Red or Pink or any other.\n  * Urine clarity: Clear, slightly Cloudy, cloudy or turbidity\n* Chemical Examination:\n\n  * Specific gravity\n  * pH\n  * Bilirubin\n  * Urobilinogen\n  * Protein\n  * Ketone\n  * Leukocyte Esterase\n* Microscopic Examination:\n\n  * Red Blood Cells:\n  * Epithelial Cells:\n  * Amorphous:\n  * Pus Cells\n  * Bacteria\n  * Yeast\n  * Casts\n  * Crystals\n\nWhere in Renal Function Test (RFT), we consider as follows:\n\n* Blood Urea Nitrogen (BUN): mg\u002FdL\n* Serum Creatinine: mg\u002FdL\n* Estimated Glomerular Filtration Rate (eGFR): mL\u002Fmin\u002F1.73 m2",[62,63,64],"Type II Diabetes Mellitus","Efficacy, Self","Safety Issues","2026-01-20",{"date":67,"type":35},"2026-01-22",{"date":69,"type":35},"2021-04-01",{"date":71,"type":20},"2027-08-31",{"name":73,"class":74},"Getz Pharma","INDUSTRY",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":52,"sex":17,"minAge":83,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":57,"phases":86,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":103},"100619905","engagement-of-community-through-participatory-learning-and-action-for-control-and-prevention-of-type-ii-diabetes-and-its-risk-factors-100619905","NCT07350694","Engagement of coMmunity Through Participatory Learning and Action for cOntrol and preVEntion of Type II Diabetes and Its Risk Factors","Engagement of coMmunity Through Participatory Learning and Action for cOntrol and preVEntion of Type II Diabetes and Its Risk Factors [EMPOWER-D-Afg]: Feasibility Trial in Rural Kabul-Afghanistan","EMPOWER-D-Afg","Inclusion Criteria:\n\n* For intervention phase: Individuals aged 20 years and above. For baseline and endline assessments (before and after the intervention): Individuals aged 30 years and above.\n* Participants residing in the randomized clusters of Kabul, Afghanistan Individuals willing to participate in the study and provide consent.\n* All individuals with normoglycemia, intermediate hyperglycaemia, and diabetes are encouraged to participate.\n* Participants who can attend the scheduled meetings and interventions as per the study protocol.\n\nExclusion Criteria:\n\n* For Intervention phase: Individuals below the age of 20 years. For baseline and endline assessments (before and after the intervention): individuals below the age of 30 years.\n* Individuals unwilling to provide consent for participation.\n* Participants with reported health conditions that may hinder their active involvement in the study.\n* Individuals with non-compliance with research protocols","20 Years",{"count":85,"type":20},250,[87],"NA","This project aims to adapt, implement, and evaluate PLA based intervention in Rural Kabul, Afghanistan for TIIDM prevention and control.",[90,62],"Diabetes Type 2",[92,93,62,94],"Community-Based Participatory Research","Participatory Learning and Action Research","Intermediate hyperglycemia","2026-01-11",{"date":65,"type":35},{"date":98,"type":35},"2024-12-24",{"date":100,"type":20},"2027-09-30",{"name":102,"class":42},"HealthNet Transcultural Psychosocial Organization",1,{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":17,"minAge":111,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":57,"phases":115,"briefSummary":116,"conditions":117,"keywords":121,"overallStatus":129,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":103},"100591439","culturally-adapted-psychological-support-for-conflict-affected-afghans-study-protocol-on-mental-health--violence-100591439","NCT06980441","Culturally Adapted Psychological Support for Conflict-Affected Afghans: Study Protocol on Mental Health & Violence","Feasibility and Acceptability of Culturally Adapted, Evidence-Informed Psychological Support on Mental Health Symptoms and Violence for Conflict-Affected Populations in Afghanistan: A Study Protocol","Inclusion Criteria:\n\n* Psychological Distress, measured at \\>15 on the Kessler Psychological Distress Scale (K10)\n* Afghan nationality\n* Age between 16 and 30\n* Ability to read and write in Dari\n\nExclusion Criteria:\n\n* Imminent suicide risk\n* Experiencing psychosis\n* Neurological or cognitive disabilities","16 Years","30 Years",{"count":114,"type":20},60,[87],"This pilot study examines the feasibility and acceptability of a culturally adapted psychological intervention-Problem Management Plus with Emotional Processing (PM+ EP)-for young Afghans aged 16-30 experiencing high psychological distress. Through a pilot randomized control trial and qualitative interviews, the study explores whether PM+ EP can reduce symptoms of anxiety, depression, PTSD, and aggression, and improve daily functioning. Findings will inform the potential for a larger trial and address critical mental health and violence prevention needs in conflict-affected Afghan communities.",[118,119,120],"Depression and Suicide Ideation","Anxiety","PTSD",[122,123,124,125,126,127,128],"Youth mental health","Afghanistan","Implementation science","Culturally adapted psychological support","Evidence informed interventions","Mental health symptoms","Psychological experiences","NOT_YET_RECRUITING","2025-05-11",{"date":132,"type":35},"2025-05-20",{"date":134,"type":20},"2025-06",{"date":136,"type":20},"2026-12",{"name":138,"class":42},"Peace of Mind Association (PoMA)",{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":143,"acronym":144,"eligibilityCriteria":145,"healthyVolunteers":11,"sex":17,"minAge":146,"maxAge":147,"enrollmentInfo":148,"targetDuration":150,"studyType":21,"phases":4,"briefSummary":151,"conditions":152,"keywords":155,"overallStatus":129,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":103},"100571067","high-flow-nasal-oxygen-therapy-an-implementation-study-in-pediatric-wards-100571067","NCT06715423","High Flow Nasal Oxygen Therapy an Implementation Study in Pediatric Wards","HFNO","Inclusion Criteria:\n\n* prescription of HFNO by clinician\n* parent consenting to the use of the data","1 Month","5 Years",{"count":149,"type":20},960,"2 Weeks","The purpose of this study is to prospectively evaluate the process of implementing HFNO in several MSF projects, varying according to geographical and programmatic contexts, population, health structures, human resources, and management. It will generate evidence on the operational feasibility (in terms of human resources, equipment, logistics and costs) of integrating HFNO into PICU standard of care, as well as on the users' and caregivers' perspectives on HFNO and on the children clinical outcomes observed where HFNO is implemented. This relevant information will guide MSF in the decision making of scaling up HFNO therapy in its projects.",[153,154],"Moderate Respiratory Distress","Severe Respiratory Distress",[156,157,158,159],"oxygen","high flow","pneumonia","pediatrics","2025-01-28",{"date":162,"type":35},"2025-01-30",{"date":164,"type":20},"2025-01",{"date":166,"type":20},"2025-12",{"name":168,"class":42},"Epicentre",{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":4,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":176,"minAge":4,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":57,"phases":179,"briefSummary":180,"conditions":181,"keywords":183,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":195},"100560062","ecd-newborn-parenting-education-program-100560062","NCT06572254","ECD Newborn Parenting Education Program","Early Childhood Newborn Parenting Education Program at Primary Health Care Facilities of Pakistan: A Feasibility Study","Inclusion Criteria:\n\n1. Normal delivery\n2. No underlying morbidities of the newborn\n3. Are not living in ultra-poverty less than 15000\u002F- total household income.\n\nExclusion Criteria:\n\n1. Newborn or mother with underlying conditions or morbidities\n2. Living under 15000 per month","FEMALE",{"count":178,"type":20},400,[87],"Early childhood development: specifically the first 1000 days of life are of crucial importance. It sets the trajectory for the future and transgenerational health. Life of a neonate is influenced by several factors of which responsive caregiving is one of the most imperative facets. In the earliest days of life, the role of responsive caregiving is vital for the child's growing brain. Interactions between the primary caregiver and the neonate in early infancy period foster social and cognitive growth, build trust, provide sense of security, and helps build brain of the young child. In resource constraints areas, particularly in primary health care settings, there is a lack of initiatives to support responsive caregiving. The investigators intend to do an implementation adaptation and assessment of impact and efficacy of early childhood newborn parenting education program at primary health care facilities of Pakistan and Afghanistan. Investigators already have a structured program at our tertiary health care setting, with this project, investigators now intend to adapt it to primary care settings of Aga Khan Health Services Pakistan and Afghanistan a) explore the impact of newborn parenting education program on parental outcomes b) conduct training for health care providers and asses their pre-post knowledge and skills and c) explore systems readiness to scale up this program at national level. The expected outcome of this research is to build a proof of concept of this intervention in primary healthcare settings and disseminate its findings for a national level scale up and to advocate the importance of it to the government sector, civil society organization and funding agencies.",[182],"Parenting",[184,185,182],"Early childhood development","Responsive caregiving","2024-08-26",{"date":188,"type":35},"2024-08-27",{"date":190,"type":35},"2023-01-01",{"date":192,"type":20},"2025-03-31",{"name":194,"class":42},"Aga Khan University",2,""]