[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"countryName\":\"Liechtenstein\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":72},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100638802","effectiveness-of-two-different-desensitizing-dental-varnishes-100638802",false,"NCT07622043","Effectiveness of Two Different Desensitizing Dental Varnishes","Effectiveness of Two Different Desensitizing Dental Varnishes: A Prospective, Randomized Split Mouth Clinical Investigation","Inclusion Criteria:\n\n* Informed Consent signed by the subject\n* Age: 18-65 years\n* Hypersensitivity assessment scale ≥ Grade 2 in\n* two non-neighboring teeth in different quadrants\n* The affected teeth are\u002Fhave: vital, caries-free, received no restorations within the last month\n* No change in medication anticipated over the next 3 months (e.g. due to upcoming surgery etc.)\n\nExclusion Criteria:\n\n* Contraindications and limitations of the MD as described in the instructions for use.\n* Known hypersensitivity or allergy to the device material (especially acrylates, mint flavouring)\n* Pregnant or other vulnerable subjects\n* Participants with severe systemic disease\n* Enrolment of employees of the dental clinic of Ivoclar Vivadent AG\n* Recent change in medication concerning Analgesics, NSAIDs, psychotropic drugs, other medications that may alter pain perception\n* Intake of analgesics prior to appointment\n* Professional desensitizing therapy in the last 3 months\n* Bleaching procedures in the last 4 weeks\n* Confounding dental conditions at test sites: defective or extensive restorations, abutment teeth for prostheses, recent restorations, pulpitis\u002Fperiapical pathology.\n* Current or recent use of desensitizing toothpastes or mouthrinses (i.e. products specifically marketed for the treatment of dentin hypersensitivity) within 4 weeks prior to enrolment","ALL","18 Years","65 Years",{"count":20,"type":21},66,"ESTIMATED","INTERVENTIONAL",[24],"NA","Dental varnishes are commonly used to relieve dentin hypersensitivity by forming a protective film that occludes dentinal tubules and reduces fluid flow. This clinical investigation aims to compare the desensitizing effect of a fluoride containing varnish with a fluoride free placebo varnish. Primary and secondary objectives include evaluating short and long term reductions in dentinal hypersensitivity, assessing patient reported outcomes and daily experiences, and monitoring the varnish's tolerability and safety.",[27,28],"Dentin Hypersensitivity","Dentin Desensitizing Agents","RECRUITING","2026-08-18",{"date":32,"type":33},"2026-08-20","ACTUAL",{"date":35,"type":33},"2026-07-13",{"date":37,"type":21},"2027-08",{"name":39,"class":40},"Ivoclar Vivadent AG","INDUSTRY",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":16,"minAge":51,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":41},"100441571","myopia-prevention-with-reading-glasses-100441571","NCT05030103","Myopia Prevention With Reading Glasses","An Open, Prospective Clinical Trial on the Use of Reading Glasses in Children to Prevent Myopia","SMART2","Inclusion Criteria:\n\n1. Children of both sexes from the age of 6\n2. Children whose parents have read and signed the declaration of consent\n3. Spherical equivalent of refraction \\\u003C-0.5 dpt.\n4. Distant vision in both eyes without correction 1.0\n5. Willingness to wear reading glasses\n6. Possibility of a five-year follow-up\n\nExclusion Criteria:\n\n1. Children who already wear glasses\n2. Astigmatism over 1.5 diopters\n3. Anisometropy greater than 1.5 diopters\n4. Eye diseases that affect refraction development",true,"6 Years","25 Years",{"count":54,"type":21},1500,[24],"The last decades have seen a significant increase in myopia in children and young adults. Possible cause: increased near-work (school, computer, smartphone). Rationale: Reading glasses support the accommodative effort of the eyes. By wearing reading glasses, there is less interference with the young eye´s physiological axial growth despite increased near-work. Main objective: does the use of reading glasses during near-work in children and adolescents reduce the incidence of myopia.",[58],"Myopia",[60],"Children, prevention","NOT_YET_RECRUITING","2023-02-22",{"date":64,"type":33},"2023-02-23",{"date":66,"type":21},"2023-10-01",{"date":68,"type":21},"2031-12-31",{"name":70,"class":71},"Reis Augenklinik AG","OTHER",""]