[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"alveolar-ridge-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:alveolar-ridge-deficiency":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100645750","novel-synthetic-membrane-for-horizontal-bone-augmentation-a-case-series-100645750",false,"NCT07701473","Novel Synthetic Membrane for Horizontal Bone Augmentation: A Case Series","Efficacy of a Novel Synthetic GBR Membrane (Inox Nanoksa G-Plus) for Horizontal Ridge Augmentation: A Case Series","Inclusion Criteria:\n\n* Partial edentulism in the maxilla or mandible requiring single or multiple implant-supported restorations.\n* Insufficient bone volume for standard implant placement, defined as:\n\n  * Horizontal defect: residual ridge width \\\u003C 5 mm at the intended implant site, OR\n  * Vertical defect: residual ridge height \\\u003C 8 mm above vital structures (mandibular canal, maxillary sinus, nasal floor).\n* Healthy oral mucosa with no signs of active infection or inflammation at the defect site.\n* Systemically healthy or with well-controlled medical conditions (American Society of Anesthesiologists - ASA class I or II).\n\nExclusion Criteria:\n\n* Untreated periodontitis or active peri-implant disease.\n* Current or previous treatment with intravenous bisphosphonates (or oral bisphosphonates for \\> 3 years).\n* Severe immunosuppression or chronic systemic corticosteroid therapy (\\> 10 mg\u002Fday prednisolone for \\> 3 months).\n* Active smoking (\\> 10 cigarettes per day). Smoking cessation for at least 2 weeks before surgery is required; heavy smokers may be excluded.\n* Pregnant or lactating women.",true,"ALL","18 Years",{"count":20,"type":21},12,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical study is to learn if the Inox Nanoksa G-Plus membrane works to rebuild bone in the upper or lower jaw (ridge augmentation) for adults who need dental implants but do not have enough bone width or height. It will also learn about the safety of this membrane and how patients feel after surgery.\n\n\\- The main questions it aims to answer are: How much pain, swelling, and bleeding do participants experience during the first week after the bone-building surgery? How much new bone width and height does the membrane help grow, as measured on a 3D X-ray (CBCT) taken 6 months after surgery? What medical problems or side effects (such as the membrane becoming visible through the gums, infection, or graft loss) do participants experience? This is a single-treatment study; all participants will receive the same surgery using the Inox Nanoksa G-Plus membrane together with a bone graft material.\n\nParticipants will:\n\nHave surgery to place the membrane and bone graft under their gums to rebuild their jawbone.\n\nTake antibiotics and pain relievers, and use a special mouth rinse for about 2 weeks after surgery.\n\nRate their pain, swelling, and bleeding on simple scales on days 1, 3, and 7 after surgery.\n\nReturn for a checkup at 1 month and have a follow-up 3D X-ray at 6 months. Undergo a second surgery at 6 months to have dental implants placed and to evaluate the newly formed bone.",[27,28],"Alveolar Ridge Deficiency","Alveolar Bone Loss",[30,31,32,33,34,35,36,37,38],"Alveolar Ridge Augmentation","Guided Bone Regeneration","Membranes, Artificial","Bone Transplantation","GBR Membrane","Synthetic Membrane","Inox Nanoksa G-Plus","Vertical Bone Defect","Dental Implant","NOT_YET_RECRUITING","2026-07-13",{"date":42,"type":43},"2026-07-14","ACTUAL",{"date":45,"type":21},"2026-09-01",{"date":47,"type":21},"2027-09-01",{"name":49,"class":50},"Cairo University","OTHER",1,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":66,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":51},"100645193","custom-made-peek-versus-ptfe-membranes-in-maxillary-alveolar-ridge-augmentation-100645193","NCT07679451","Custom-Made PEEK Versus PTFE Membranes in Maxillary Alveolar Ridge Augmentation","Custom-Made Polyether Ether Ketone Membrane Versus Polytetrafluoroethylene Membrane in Maxillary Alveolar Ridge Augmentation: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\nAge between 20 and 45 years. Male or female participants. Presence of single or multiple missing teeth associated with vertical alveolar defects (vertical bone height less than 8 mm), horizontal alveolar defects (ridge width less than 6 mm), or combined defects in the maxillary esthetic zone requiring alveolar ridge augmentation before implant placement.\n\nGood oral hygiene.\n\nExclusion Criteria:\n\nUncontrolled medical disorders contraindicating surgical intervention. Systemic diseases or medications affecting bone metabolism. Current or previous bisphosphonate therapy. History of radiotherapy. History of chemotherapy. Smokers.","20 Years","45 Years",{"count":62,"type":21},30,[24],"This randomized controlled clinical study aims to evaluate and compare the effectiveness of custom-made polyether ether ketone (PEEK) membranes versus polytetrafluoroethylene (PTFE) membranes in guided bone regeneration for maxillary alveolar ridge augmentation in the esthetic zone. Thirty patients requiring ridge augmentation prior to dental implant placement will be enrolled and randomly allocated into two equal groups. Group A will receive customized PEEK membranes, while Group B will be treated with PTFE membranes. Clinical and radiographic assessments, including cone beam computed tomography (CBCT), will be performed immediately postoperatively, at 6 months, and at 12 months to evaluate volumetric, horizontal, and vertical bone gain as well as soft tissue healing and complication rates.",[27],[31,67,68,69,70],"PEEK membrane","PTFE membrane","Ridge augmentation","Maxillary ridge augmentation","RECRUITING","2026-06-25",{"date":74,"type":43},"2026-07-01",{"date":76,"type":43},"2026-01-01",{"date":78,"type":21},"2027-02-01",{"name":80,"class":50},"Mansoura University"]