[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"amputation-of-lower-extremity-all-causes\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:amputation-of-lower-extremity-all-causes":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100598831","gait-and-energy-expenditure-in-children-with-lower-limb-amputation-mapede-100598831",false,"NCT07076602","Gait and Energy Expenditure in Children With Lower Limb Amputation (MAPEDE)","Relation Between Kinematic Gait Parameters and Energy Expenditure in Children With Unilateral Lower Limb Amputation","MAPEDE","Inclusion Criteria:\n\n* Minor aged 7 and over\n* Congenital (transverse agenesis with break in limb continuity) or acquired (any etiology) unilateral transfemoral or transtibial amputation. \\[In the case of femoral agenesis, the flexion axis of the prosthetic knee must coincide with the contralateral one to optimize the analysis of the kinematic parameters of gait\\].\n* Definitive prosthesis in place (no restriction on choice of prosthetic components)\n* Legal representatives not opposing participation in the study for the child\n\nExclusion Criteria:\n\n* Revision surgery on the residual limb within the last 3 months\n* Progressive pathology associated with amputation (unstabilized sarcoma for example) which can strongly influence walking and\u002For energy expenditure\n* Cognitive and\u002For behavioral disorders that may affect compliance or test performance\n* Patient already included in an interventional research protocol that could lead to bias in the present study","ALL","7 Years","17 Years",{"count":21,"type":22},48,"ESTIMATED","OBSERVATIONAL","In lower limb amputation, prosthetic gait has been shown to be particularly energy-intensive. While energy expenditure has been the focus of many studies in adult amputees, this area of research is less developed for paediatric amputees. However, the increase in energy expenditure has implications for the physical, gait, and balance abilities of amputees of all ages. Combined with physical deconditioning, it exposes the patient to a greater risk of a sedentary lifestyle and weight gain, which is detrimental to their prosthetic training, autonomy, and length of hospital stay. However, this increased expenditure and deconditioning is not currently the subject of systematic evaluation in routine clinical practice for this population. In contrast to adults, the gait pattern of children amputees is poorly described, and the relation between energy expenditure and gait is rarely discussed. Oxygen consumption is the most widely used outcome to assess energy expenditure in studies. The main aim of this study was to identify the kinematic gait parameters obtained by quantified gait analysis associated with oxygen consumption during a 6-minute test in children with lower-limb amputations aged 7 years or older. This study also makes it possible to evaluate with the child's physician and rehabilitators the usefulness of measuring energy expenditure to guide medical decisions and rehabilitative care. Finally, it will allow the validation of a tool for this population for measuring energy expenditure that has been presented as more easily applicable in clinical routine than the measurement of oxygen consumption, the Physiological Cost Index (PCI). The validity and reliability of the PCI will therefore be evaluated. This study will therefore facilitate the assessment and monitoring of child amputees and provide guidance for the provision of an evidence-based rehabilitation program.",[26],"Amputation of Lower Extremity, All Causes",[28,29,30,31,32,33,34],"Children","gait analysis","energy expenditure","oxygen consumption","lower extremity amputation","kinematic","psychometry","RECRUITING","2026-09-15",{"date":38,"type":39},"2026-09-16","ACTUAL",{"date":41,"type":39},"2025-10-13",{"date":43,"type":22},"2027-10-13",{"name":45,"class":46},"Rennes University Hospital","OTHER",8]