[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"antifungal-agents\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:antifungal-agents":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100659753","nanoparticle-based-prunus-salicina-extract-vs-clotrimazole-for-otomycosis-100659753",false,"NCT07867223","Nanoparticle-Based Prunus Salicina Extract vs. Clotrimazole for Otomycosis","Comparative Efficacy of Nanoparticle-Based Prunus Salicina Methanolic Extract Drops Versus Standard Antifungal Therapy for Otomycosis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 16-80 years.\n* Confirmed clinical diagnosis of otomycosis via otoscopic examination (visible fungal elements such as hyphae, spores, curdy precipitates).\n* Willing and able to provide informed consent.\n\nExclusion Criteria:\n\n* Otitis media, malignant otitis externa, chronic mucosal ear discharge.\n* Previous ear surgery or anatomical anomalies.\n* Systemic antifungal or corticosteroid therapy within two weeks prior.\n* Pregnancy or lactation.\n* Concurrent bacterial infection.\n* Diabetes mellitus.","ALL","16 Years","80 Years",{"count":20,"type":21},180,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled superiority trial evaluates the anti-otomycotic efficacy of Prunus salicina methanolic extract in two formulations (standard drops and chitosan nanoparticle-based drops) compared to standard 1% clotrimazole drops in patients diagnosed with otomycosis.",[27,28],"Otomycosis","Antifungal Agents","RECRUITING","2026-10-05",{"date":32,"type":33},"2026-10-09","ACTUAL",{"date":35,"type":33},"2025-07-15",{"date":37,"type":21},"2026-11-15",{"name":39,"class":40},"Deraya University","OTHER"]